Repeat instability as the basis for human diseases and as a potential target for therapy

Nature Reviews Molecular Cell Biology

Volumn 11, Issue 3, 2010, Pages 165-170

  Castel, Arturo López ^a   Cleary, John D ^a,b   Pearson, Christopher E ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SPECIFICITY; DISEASE COURSE; DISEASE SEVERITY; DNA METABOLISM; DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; DNA SEQUENCE; DNA STRUCTURE; DRUG TARGETING; EPIGENETICS; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; HUMAN; NEUROLOGIC DISEASE; NEUROMUSCULAR DISEASE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; RNA STRUCTURE;

ANIMALS; BASE SEQUENCE; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DRUG THERAPY; GENETIC PREDISPOSITION TO DISEASE; GENOMIC INSTABILITY; HUMANS; MICE; MODELS, BIOLOGICAL; TRANSCRIPTION, GENETIC; TRINUCLEOTIDE REPEAT EXPANSION; TRINUCLEOTIDE REPEATS;

EID: 77649144557     PISSN: 14710072     EISSN: 14710080     Source Type: Journal    
DOI: 10.1038/nrm2854     Document Type: Review

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