The kinase DYRK phosphorylates protein-synthesis initiation factor elF2Bε at Ser539 and the microtubule-associated protein tau at Thr212: Potential role for DYRK as a glycogen synthase kinase 3-priming kinase

Biochemical Journal

Volumn 355, Issue 3, 2001, Pages 609-615

  Woods, Yvonne L ^a   Cohen, Philip ^a   Becker, Walter ^b   Jakes, Ross ^c   Goedert, Michel ^c   Wang, Xuemin ^a   Proud, Christopher G ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Alzheimer's disease; Down's syndrome; Insulin action; Protein phosphorylation; Signal transduction

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; BRAIN; DISEASES; ENZYMES;

INITIATION FACTORS;

BIOCHEMISTRY;

GLYCOGEN SYNTHASE KINASE 3; INITIATION FACTOR 2; PROLINE; PROTEIN KINASE; PROTEIN KINASE DYRK; PROTEIN SUBUNIT; SERINE; TAU PROTEIN; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION;

ANIMALIA; EUKARYOTA;

EID: 0035340295     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3550609     Document Type: Article

References (30)

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