-
1
-
-
49549088134
-
CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice
-
[PubMed: 18602275]
-
A postol BL, Simmons DA, Zuccato C, Illes K, Pallos J, Casale M, Conforti P, Ramos C, Roarke M, Kathuria S, et al. CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice. Mol Cell Neurosci. 2008; 39:8-20. [PubMed: 18602275]
-
(2008)
Mol Cell Neurosci
, vol.39
, pp. 8-20
-
-
A Postol, B.L.1
Simmons, D.A.2
Zuccato, C.3
Illes, K.4
Pallos, J.5
Casale, M.6
Conforti, P.7
Ramos, C.8
Roarke, M.9
Kathuria, S.10
-
2
-
-
14844359962
-
Automated microscope system for determining factors that predict neuronal fate
-
[PubMed: 15738408]
-
Arrasate M, Finkbeiner S. Automated microscope system for determining factors that predict neuronal fate. Proc Natl Acad Sci U S A. 2005; 102:3840-3845. [PubMed: 15738408]
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3840-3845
-
-
Arrasate, M.1
Finkbeiner, S.2
-
3
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
[PubMed: 15483602]
-
Arrasate M, Mitra S, Schweitzer ES, Segal MR, Finkbeiner S. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature. 2004; 431:805-810. [PubMed: 15483602]
-
(2004)
Nature
, vol.431
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
4
-
-
55949130712
-
Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats
-
[PubMed: 18922775]
-
Aubry L, Bugi A, Lefort N, Rousseau F, Peschanski M, Perrier AL. Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats. Proc Natl Acad Sci U S A. 2008; 105:16707-16712. [PubMed: 18922775]
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16707-16712
-
-
Aubry, L.1
Bugi, A.2
Lefort, N.3
Rousseau, F.4
Peschanski, M.5
Perrier, A.L.6
-
5
-
-
21544450545
-
P53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease
-
[PubMed: 15996546]
-
Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, et al. p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. Neuron. 2005; 47:29-41. [PubMed: 15996546]
-
(2005)
Neuron
, vol.47
, pp. 29-41
-
-
Bae, B.I.1
Xu, H.2
Igarashi, S.3
Fujimuro, M.4
Agrawal, N.5
Taya, Y.6
Hayward, S.D.7
Moran, T.H.8
Montell, C.9
Ross, C.A.10
-
6
-
-
0036345741
-
Impaired glutamate transport and glutamate-glutamine cycling: Downstream effects of the Huntington mutation
-
[PubMed: 12135980]
-
Behrens PF, Franz P, Woodman B, Lindenberg KS, Landwehrmeyer GB. Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation. Brain. 2002; 125:1908-1922. [PubMed: 12135980]
-
(2002)
Brain
, vol.125
, pp. 1908-1922
-
-
Behrens, P.F.1
Franz, P.2
Woodman, B.3
Lindenberg, K.S.4
Landwehrmeyer, G.B.5
-
7
-
-
1842576585
-
A role for lipoprotein lipase during synaptic remodeling in the adult mouse brain
-
[PubMed: 15056458]
-
Blain JF, Paradis E, Gaudreault SB, Champagne D, Richard D, Poirier J. A role for lipoprotein lipase during synaptic remodeling in the adult mouse brain. Neurobiol Dis. 2004; 15:510-519. [PubMed: 15056458]
-
(2004)
Neurobiol Dis
, vol.15
, pp. 510-519
-
-
Blain, J.F.1
Paradis, E.2
Gaudreault, S.B.3
Champagne, D.4
Richard, D.5
Poirier, J.6
-
8
-
-
79952120621
-
Derivation of Huntington's disease-affected human embryonic stem cell lines
-
[PubMed: 20649476]
-
Bradley CK, Scott HA, Chami O, Peura TT, Dumevska B, Schmidt U, Stojanov T. Derivation of Huntington's disease-affected human embryonic stem cell lines. Stem Cells Dev. 2011; 20:495-502. [PubMed: 20649476]
-
(2011)
Stem Cells Dev
, vol.20
, pp. 495-502
-
-
Bradley, C.K.1
Scott, H.A.2
Chami, O.3
Peura, T.T.4
Dumevska, B.5
Schmidt, U.6
Stojanov, T.7
-
9
-
-
84863230167
-
The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity
-
2012. [PubMed: 22405424]
-
Camnasio S, Carri AD, Lombardo A, Grad I, Mariotti C, Castucci A, Rozell B, Riso PL, Castiglioni V, Zuccato C, Rochon C, Takashima Y, Diaferia G, Biunno I, Gellera C, Jaconi M, Smith A, Hovatta O, Naldini L, Di Donato S, Feki A, Cattaneo E. The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity. Neurobiology of Disease. 2012; 46:41-51. 2012. [PubMed: 22405424]
-
(2012)
Neurobiology of Disease
, vol.46
, pp. 41-51
-
-
Camnasio, S.1
Carri, A.D.2
Lombardo, A.3
Grad, I.4
Mariotti, C.5
Castucci, A.6
Rozell, B.7
Riso, P.L.8
Castiglioni, V.9
Zuccato, C.10
Rochon, C.11
Takashima, Y.12
Diaferia, G.13
Biunno, I.14
Gellera, C.15
Jaconi, M.16
Smith, A.17
Hovatta, O.18
Naldini, L.19
Di Donato, S.20
Feki, A.21
Cattaneo, E.22
more..
-
10
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group
-
[PubMed: 8458085]
-
Consortium TH. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group. Cell. 1993; 72:971-983. [PubMed: 8458085]
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
Consortium, T.H.1
-
11
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
[PubMed: 19098894]
-
Ebert AD, Yu J, Rose FF Jr, Mattis VB, Lorson CL, Thomson JA, Svendsen CN. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature. 2009; 457:277-280. [PubMed: 19098894]
-
(2009)
Nature
, vol.457
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose, F.F.3
Mattis, V.B.4
Lorson, C.L.5
Thomson, J.A.6
Svendsen, C.N.7
-
12
-
-
77958156339
-
In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: A correlation with Huntington's disease subjects
-
[PubMed: 20494921]
-
Faideau M, Kim J, Cormier K, Gilmore R, Welch M, Auregan G, Dufour N, Guillermier M, Brouillet E, Hantraye P, et al. In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects. Hum Mol Genet. 2010; 19:3053-3067. [PubMed: 20494921]
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3053-3067
-
-
Faideau, M.1
Kim, J.2
Cormier, K.3
Gilmore, R.4
Welch, M.5
Auregan, G.6
Dufour, N.7
Guillermier, M.8
Brouillet, E.9
Hantraye, P.10
-
13
-
-
34047100940
-
N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease
-
[PubMed: 17188796]
-
Fan MM, Raymond LA. N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease. Prog Neurobiol. 2007; 81:272-293. [PubMed: 17188796]
-
(2007)
Prog Neurobiol
, vol.81
, pp. 272-293
-
-
Fan, M.M.1
Raymond, L.A.2
-
14
-
-
77954362528
-
Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression
-
[PubMed: 20442398]
-
Gines S, Paoletti P, Alberch J. Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression. J Biol Chem. 2010; 285:21537-21548. [PubMed: 20442398]
-
(2010)
J Biol Chem
, vol.285
, pp. 21537-21548
-
-
Gines, S.1
Paoletti, P.2
Alberch, J.3
-
15
-
-
33644783812
-
Regional and cellular gene expression changes in human Huntington's disease brain
-
[PubMed: 16467349]
-
Hodges A, Strand AD, Aragaki AK, Kuhn A, Sengstag T, Hughes G, Elliston LA, Hartog C, Goldstein DR, Thu D, et al. Regional and cellular gene expression changes in human Huntington's disease brain. Hum Mol Genet. 2006; 15:965-977. [PubMed: 16467349]
-
(2006)
Hum Mol Genet
, vol.15
, pp. 965-977
-
-
Hodges, A.1
Strand, A.D.2
Aragaki, A.K.3
Kuhn, A.4
Sengstag, T.5
Hughes, G.6
Elliston, L.A.7
Hartog, C.8
Goldstein, D.R.9
Thu, D.10
-
16
-
-
79959796625
-
HD CAG-correlated gene expression changes support a simple dominant gain of function
-
[PubMed: 21536587]
-
Jacobsen JC, Gregory GC, Woda JM, Thompson MN, Coser KR, Murthy V, Kohane IS, Gusella JF, Seong IS, MacDonald ME, et al. HD CAG-correlated gene expression changes support a simple dominant gain of function. Hum Mol Genet. 2011; 20:2846-2860. [PubMed: 21536587]
-
(2011)
Hum Mol Genet
, vol.20
, pp. 2846-2860
-
-
Jacobsen, J.C.1
Gregory, G.C.2
Woda, J.M.3
Thompson, M.N.4
Coser, K.R.5
Murthy, V.6
Kohane, I.S.7
Gusella, J.F.8
Seong, I.S.9
Macdonald, M.E.10
-
17
-
-
80555149443
-
Cholesterol metabolism in Huntington disease
-
[PubMed: 21894212]
-
Karasinska JM, Hayden MR. Cholesterol metabolism in Huntington disease. Nat Rev Neurol. 2011; 7:561-572. [PubMed: 21894212]
-
(2011)
Nat Rev Neurol
, vol.7
, pp. 561-572
-
-
Karasinska, J.M.1
Hayden, M.R.2
-
18
-
-
84355161952
-
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease
-
[PubMed: 22113611]
-
Koch P, Breuer P, Peitz M, Jungverdorben J, Kesavan J, Poppe D, Doerr J, Ladewig J, Mertens J, Tuting T, et al. Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease. Nature. 2011; 480:543-546. [PubMed: 22113611]
-
(2011)
Nature
, vol.480
, pp. 543-546
-
-
Koch, P.1
Breuer, P.2
Peitz, M.3
Jungverdorben, J.4
Kesavan, J.5
Poppe, D.6
Doerr, J.7
Ladewig, J.8
Mertens, J.9
Tuting, T.10
-
19
-
-
77349122826
-
CAG-repeat length and the age of onset in Huntington disease (HD): A review and validation study of statistical approaches
-
[PubMed: 19548255]
-
Langbehn DR, Hayden MR, Paulsen JS. CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches. Am J Med Genet B Neuropsychiatr Genet. 2010; 153B:397-408. [PubMed: 19548255]
-
(2010)
Am J Med Genet B Neuropsychiatr Genet
, vol.153B
, pp. 397-408
-
-
Langbehn, D.R.1
Hayden, M.R.2
Paulsen, J.S.3
-
20
-
-
14644430451
-
Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila
-
Lievens JC, Rival T, Iche M, Chneiweiss H, Birman S. Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila. Hum Mol Genet. 2005
-
(2005)
Hum Mol Genet
-
-
Lievens, J.C.1
Rival, T.2
Iche, M.3
Chneiweiss, H.4
Birman, S.5
-
21
-
-
0034702030
-
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
-
[PubMed: 10814708]
-
Luthi-Carter R, Strand A, Peters NL, Solano SM, Hollingsworth ZR, Menon AS, Frey AS, Spektor BS, Penney EB, Schilling G, et al. Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum Mol Genet. 2000; 9:1259-1271. [PubMed: 10814708]
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1259-1271
-
-
Luthi-Carter, R.1
Strand, A.2
Peters, N.L.3
Solano, S.M.4
Hollingsworth, Z.R.5
Menon, A.S.6
Frey, A.S.7
Spektor, B.S.8
Penney, E.B.9
Schilling, G.10
-
22
-
-
79952710923
-
Induced pluripotent stem cells: A new revolution for clinical neurology?
-
[PubMed: 21435601]
-
Mattis VB, Svendsen CN. Induced pluripotent stem cells: a new revolution for clinical neurology? Lancet Neurol. 2011; 10:383-394. [PubMed: 21435601]
-
(2011)
Lancet Neurol
, vol.10
, pp. 383-394
-
-
Mattis, V.B.1
Svendsen, C.N.2
-
23
-
-
77955500335
-
Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease
-
[PubMed: 20670829]
-
Miller JP, Holcomb J, Al-Ramahi I, de Haro M, Gafni J, Zhang N, Kim E, Sanhueza M, Torcassi C, Kwak S, et al. Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease. Neuron. 2010; 67:199-212. [PubMed: 20670829]
-
(2010)
Neuron
, vol.67
, pp. 199-212
-
-
Miller, J.P.1
Holcomb, J.2
Al-Ramahi, I.3
De Haro, M.4
Gafni, J.5
Zhang, N.6
Kim, E.7
Sanhueza, M.8
Torcassi, C.9
Kwak, S.10
-
24
-
-
76049118555
-
Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease
-
[PubMed: 19955426]
-
Molero AE, Gokhan S, Gonzalez S, Feig JL, Alexandre LC, Mehler MF. Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease. Proc Natl Acad Sci U S A. 2009; 106:21900-21905. [PubMed: 19955426]
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 21900-21905
-
-
Molero, A.E.1
Gokhan, S.2
Gonzalez, S.3
Feig, J.L.4
Alexandre, L.C.5
Mehler, M.F.6
-
25
-
-
79952172335
-
LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress
-
[PubMed: 21362567]
-
Nguyen HN, Byers B, Cord B, Shcheglovitov A, Byrne J, Gujar P, Kee K, Schule B, Dolmetsch RE, Langston W, et al. LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell. 2011; 8:267-280. [PubMed: 21362567]
-
(2011)
Cell Stem Cell
, vol.8
, pp. 267-280
-
-
Nguyen, H.N.1
Byers, B.2
Cord, B.3
Shcheglovitov, A.4
Byrne, J.5
Gujar, P.6
Kee, K.7
Schule, B.8
Dolmetsch, R.E.9
Langston, W.10
-
26
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
[PubMed: 18691744]
-
Park IH, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, Lensch MW, Cowan C, Hochedlinger K, Daley GQ. Disease-specific induced pluripotent stem cells. Cell. 2008; 134:877-886. [PubMed: 18691744]
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.H.1
Arora, N.2
Huo, H.3
Maherali, N.4
Ahfeldt, T.5
Shimamura, A.6
Lensch, M.W.7
Cowan, C.8
Hochedlinger, K.9
Daley, G.Q.10
-
27
-
-
79952255488
-
Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene
-
[PubMed: 21368041]
-
Pruunsild P, Sepp M, Orav E, Koppel I, Timmusk T. Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene. J Neurosci. 2011; 31:3295-3308. [PubMed: 21368041]
-
(2011)
J Neurosci
, vol.31
, pp. 3295-3308
-
-
Pruunsild, P.1
Sepp, M.2
Orav, E.3
Koppel, I.4
Timmusk, T.5
-
28
-
-
79957440957
-
Striatal neurons expressing full-length mutant huntingtin exhibit decreased Ncadherin and altered neuritogenesis
-
[PubMed: 21447599]
-
Reis SA, Thompson MN, Lee JM, Fossale E, Kim HH, Liao JK, Moskowitz MA, Shaw SY, Dong L, Haggarty SJ, et al. Striatal neurons expressing full-length mutant huntingtin exhibit decreased Ncadherin and altered neuritogenesis. Hum Mol Genet. 2011; 20:2344-2355. [PubMed: 21447599]
-
(2011)
Hum Mol Genet
, vol.20
, pp. 2344-2355
-
-
Reis, S.A.1
Thompson, M.N.2
Lee, J.M.3
Fossale, E.4
Kim, H.H.5
Liao, J.K.6
Moskowitz, M.A.7
Shaw, S.Y.8
Dong, L.9
Haggarty, S.J.10
-
29
-
-
84856963229
-
Age, CAG repeat length, and clinical progression in Huntington's disease
-
[PubMed: 22173986]
-
Rosenblatt A, Kumar BV, Mo A, Welsh CS, Margolis RL, Ross CA. Age, CAG repeat length, and clinical progression in Huntington's disease. Mov Disord. 2012; 27:272-276. [PubMed: 22173986]
-
(2012)
Mov Disord
, vol.27
, pp. 272-276
-
-
Rosenblatt, A.1
Kumar, B.V.2
Mo, A.3
Welsh, C.S.4
Margolis, R.L.5
Ross, C.A.6
-
30
-
-
3142514201
-
Protein aggregation and neurodegenerative disease
-
[PubMed: 15272267]
-
Ross CA, Poirier MA. Protein aggregation and neurodegenerative disease. Nat Med. 2004; 10(Suppl):S10-S17. [PubMed: 15272267]
-
(2004)
Nat Med
, vol.10
, pp. S10-S17
-
-
Ross, C.A.1
Poirier, M.A.2
-
31
-
-
78650031174
-
Huntington's disease: From molecular pathogenesis to clinical treatment
-
[PubMed: 21163446]
-
Ross CA, Tabrizi SJ. Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurol. 2011; 10:83-98. [PubMed: 21163446]
-
(2011)
Lancet Neurol
, vol.10
, pp. 83-98
-
-
Ross, C.A.1
Tabrizi, S.J.2
-
32
-
-
33750706557
-
Transcription meets metabolism in neurodegeneration
-
[PubMed: 17088887]
-
Ross CA, Thompson LM. Transcription meets metabolism in neurodegeneration. Nat Med. 2006; 12:1239-1241. [PubMed: 17088887]
-
(2006)
Nat Med
, vol.12
, pp. 1239-1241
-
-
Ross, C.A.1
Thompson, L.M.2
-
33
-
-
38449103454
-
Molecular evolution of the human SRPX2 gene that causes brain disorders of the Rolandic and Sylvian speech areas
-
[PubMed: 17942002]
-
Royer B, Soares DC, Barlow PN, Bontrop RE, Roll P, Robaglia-Schlupp A, Blancher A, Levasseur A, Cau P, Pontarotti P, et al. Molecular evolution of the human SRPX2 gene that causes brain disorders of the Rolandic and Sylvian speech areas. BMC Genet. 2007; 8:72. [PubMed: 17942002]
-
(2007)
BMC Genet
, vol.8
, pp. 72
-
-
Royer, B.1
Soares, D.C.2
Barlow, P.N.3
Bontrop, R.E.4
Roll, P.5
Robaglia-Schlupp, A.6
Blancher, A.7
Levasseur, A.8
Cau, P.9
Pontarotti, P.10
-
34
-
-
79955786943
-
Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells
-
[PubMed: 21508222]
-
Seibler P, Graziotto J, Jeong H, Simunovic F, Klein C, Krainc D. Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells. J Neurosci. 2011; 31:5970-5976. [PubMed: 21508222]
-
(2011)
J Neurosci
, vol.31
, pp. 5970-5976
-
-
Seibler, P.1
Graziotto, J.2
Jeong, H.3
Simunovic, F.4
Klein, C.5
Krainc, D.6
-
35
-
-
26444441008
-
HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism
-
[PubMed: 16115812]
-
Seong IS, Ivanova E, Lee JM, Choo YS, Fossale E, Anderson M, Gusella JF, Laramie JM, Myers RH, Lesort M, et al. HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism. Hum Mol Genet. 2005; 14:2871-2880. [PubMed: 16115812]
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2871-2880
-
-
Seong, I.S.1
Ivanova, E.2
Lee, J.M.3
Choo, Y.S.4
Fossale, E.5
Erson, M.6
Gusella, J.F.7
Laramie, J.M.8
Myers, R.H.9
Lesort, M.10
-
36
-
-
34447324387
-
Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain
-
[PubMed: 17409200]
-
Shelbourne PF, Keller-McGandy C, Bi WL, Yoon SR, Dubeau L, Veitch NJ, Vonsattel JP, Wexler NS, Arnheim N, Augood SJ. Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain. Hum Mol Genet. 2007; 16:1133-1142. [PubMed: 17409200]
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1133-1142
-
-
Shelbourne, P.F.1
Keller-McGandy, C.2
Bi, W.L.3
Yoon, S.R.4
Dubeau, L.5
Veitch, N.J.6
Vonsattel, J.P.7
Wexler, N.S.8
Arnheim, N.9
Augood, S.J.10
-
37
-
-
0027377151
-
Correlation between the onset age of Huntington's disease and length of the trinucleotide repeat in IT-15
-
Stine OC, Pleasant N, Franz ML, Abbott MH, Folstein SE, Ross CA. Correlation between the onset age of Huntington's disease and length of the trinucleotide repeat in IT-15. Hum Mol Genetics. 1993; 2:1547-1549.
-
(1993)
Hum Mol Genetics
, vol.2
, pp. 1547-1549
-
-
Stine, O.C.1
Pleasant, N.2
Franz, M.L.3
Abbott, M.H.4
Folstein, S.E.5
Ross, C.A.6
-
38
-
-
0032409396
-
A new method for the rapid and long term growth of human neural precursor cells
-
[PubMed: 9874150]
-
Svendsen CN, ter Borg MG, Armstrong RJ, Rosser AE, Chandran S, Ostenfeld T, Caldwell MA. A new method for the rapid and long term growth of human neural precursor cells. J Neurosci Methods. 1998; 85:141-152. [PubMed: 9874150]
-
(1998)
J Neurosci Methods
, vol.85
, pp. 141-152
-
-
Svendsen, C.N.1
Ter Borg, M.G.2
Armstrong, R.J.3
Rosser, A.E.4
Chandran, S.5
Ostenfeld, T.6
Caldwell, M.A.7
-
39
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
[PubMed: 18035408]
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomodo K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007; 131:861-872. [PubMed: 18035408]
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomodo, K.6
Yamanaka, S.7
-
40
-
-
10644273486
-
High mobility group box protein-1 inhibits microglial Abeta clearance and enhances Abeta neurotoxicity
-
[PubMed: 15499593]
-
Takata K, Kitamura Y, Tsuchiya D, Kawasaki T, Taniguchi T, Shimohama S. High mobility group box protein-1 inhibits microglial Abeta clearance and enhances Abeta neurotoxicity. J Neurosci Res. 2004; 78:880-891. [PubMed: 15499593]
-
(2004)
J Neurosci Res
, vol.78
, pp. 880-891
-
-
Takata, K.1
Kitamura, Y.2
Tsuchiya, D.3
Kawasaki, T.4
Taniguchi, T.5
Shimohama, S.6
-
41
-
-
79961219601
-
Important Role of Oxidative Stress Biomarkers in Huntington's Disease
-
[PubMed: 21678912]
-
Tunez I, Sanchez-Lopez F, Aguera E, Fernandez-Bolanos R, Sanchez FM, Tasset-Cuevas I. Important Role of Oxidative Stress Biomarkers in Huntington's Disease. J Med Chem. 2011; 54:5602-5606. [PubMed: 21678912]
-
(2011)
J Med Chem
, vol.54
, pp. 5602-5606
-
-
Tunez, I.1
Sanchez-Lopez, F.2
Aguera, E.3
Fernandez-Bolanos, R.4
Sanchez, F.M.5
Tasset-Cuevas, I.6
-
43
-
-
33846225133
-
Huntington's disease
-
[PubMed: 17240289]
-
Walker FO. Huntington's disease. Lancet. 2007; 369:218-228. [PubMed: 17240289]
-
(2007)
Lancet
, vol.369
, pp. 218-228
-
-
Walker, F.O.1
-
44
-
-
70449534692
-
Polymorphism of HD and UCHL-1 genes in Huntington's disease
-
[PubMed: 19683447]
-
Xu EH, Tang Y, Li D, Jia JP. Polymorphism of HD and UCHL-1 genes in Huntington's disease. J Clin Neurosci. 2009; 16:1473-1477. [PubMed: 19683447]
-
(2009)
J Clin Neurosci
, vol.16
, pp. 1473-1477
-
-
Xu, E.H.1
Tang, Y.2
Li, D.3
Jia, J.P.4
-
45
-
-
65649116572
-
Human induced pluripotent stem cells free of vector and transgene sequences
-
[PubMed: 19325077]
-
Yu J, Hu K, Smuga-Otta K, Tian S, Stewart R, Slukvin I, Thomson JA. Human induced pluripotent stem cells free of vector and transgene sequences. Science. 2009; 324:797-801. [PubMed: 19325077]
-
(2009)
Science
, vol.324
, pp. 797-801
-
-
Yu, J.1
Hu, K.2
Smuga-Otta, K.3
Tian, S.4
Stewart, R.5
Slukvin, I.6
Thomson, J.A.7
-
46
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
[PubMed: 18029452]
-
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science. 2007; 318:1917-1920. [PubMed: 18029452]
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
Nie, J.7
Jonsdottir, G.A.8
Ruotti, V.9
Stewart, R.10
-
47
-
-
84873337576
-
Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem Cells
-
2:RRN1193[PubMed: 21037797]
-
Zhang N, An MC, Montoro D, Ellerby LM. Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem Cells. PLoS Curr. 2010; 2:RRN1193. [PubMed: 21037797]
-
(2010)
Plos Curr
-
-
Zhang, N.1
An, M.C.2
Montoro, D.3
Ellerby, L.M.4
-
48
-
-
68849083063
-
Brain-derived neurotrophic factor in neurodegenerative diseases
-
[PubMed: 19498435]
-
Zuccato C, Cattaneo E. Brain-derived neurotrophic factor in neurodegenerative diseases. Nat Rev Neurol. 2009; 5:311-322. [PubMed: 19498435]
-
(2009)
Nat Rev Neurol
, vol.5
, pp. 311-322
-
-
Zuccato, C.1
Cattaneo, E.2
-
49
-
-
77955643169
-
Molecular mechanisms and potential therapeutical targets in Huntington's disease
-
[PubMed: 20664076]
-
Zuccato C, Valenza M, Cattaneo E. Molecular mechanisms and potential therapeutical targets in Huntington's disease. Physiol Rev. 2010; 90:905-981. [PubMed: 20664076]
-
(2010)
Physiol Rev
, vol.90
, pp. 905-981
-
-
Zuccato, C.1
Valenza, M.2
Cattaneo, E.3
|