-
1
-
-
34347342722
-
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors
-
Agarwal, N., Pacher, P., Tegeder, I., Amaya, F., Constantin, C.E., Brenner, G.J., Rubino, T., Michalski, C.W., Marsicano, G., Monory, K., Mackie, K., Marian, C., Batkai, S., Parolaro, D., Fischer, M.J., Reeh, P., Kunos, G., Kress, M., Lutz, B., Woolf, C.J. & Kuner, R. (2007) Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat. Neurosci., 10, 870-879.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 870-879
-
-
Agarwal, N.1
Pacher, P.2
Tegeder, I.3
Amaya, F.4
Constantin, C.E.5
Brenner, G.J.6
Rubino, T.7
Michalski, C.W.8
Marsicano, G.9
Monory, K.10
Mackie, K.11
Marian, C.12
Batkai, S.13
Parolaro, D.14
Fischer, M.J.15
Reeh, P.16
Kunos, G.17
Kress, M.18
Lutz, B.19
Woolf, C.J.20
Kuner, R.21
more..
-
2
-
-
64749114255
-
Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain
-
Ahn, K., Johnson, D.S., Mileni, M., Beidler, D., Long, J.Z., McKinney, M.K., Weerapana, E., Sadagopan, N., Liimatta, M., Smith, S.E., Lazerwith, S., Stiff, C., Kamtekar, S., Bhattacharya, K., Zhang, Y., Swaney, S., Van Becelaere, K., Stevens, R.C. & Cravatt, B.F. (2009) Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chem. Biol., 16, 411-420.
-
(2009)
Chem. Biol.
, vol.16
, pp. 411-420
-
-
Ahn, K.1
Johnson, D.S.2
Mileni, M.3
Beidler, D.4
Long, J.Z.5
McKinney, M.K.6
Weerapana, E.7
Sadagopan, N.8
Liimatta, M.9
Smith, S.E.10
Lazerwith, S.11
Stiff, C.12
Kamtekar, S.13
Bhattacharya, K.14
Zhang, Y.15
Swaney, S.16
Van Becelaere, K.17
Stevens, R.C.18
Cravatt, B.F.19
-
3
-
-
79959506821
-
Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain
-
Ahn, K., Smith, S.E., Liimatta, M.B., Beidler, D., Sadagopan, N., Dudley, D.T., Young, T., Wren, P., Zhang, Y., Swaney, S., Van Becelaere, K., Blankman, J.L., Nomura, D.K., Bhattachar, S.N., Stiff, C., Nomanbhoy, T.K., Weerapana, E., Johnson, D.S. & Cravatt, B.F. (2011) Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain. J. Pharmacol. Exp. Ther., 338, 114-124.
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.338
, pp. 114-124
-
-
Ahn, K.1
Smith, S.E.2
Liimatta, M.B.3
Beidler, D.4
Sadagopan, N.5
Dudley, D.T.6
Young, T.7
Wren, P.8
Zhang, Y.9
Swaney, S.10
Van Becelaere, K.11
Blankman, J.L.12
Nomura, D.K.13
Bhattachar, S.N.14
Stiff, C.15
Nomanbhoy, T.K.16
Weerapana, E.17
Johnson, D.S.18
Cravatt, B.F.19
-
4
-
-
0022557314
-
The many possible roles of opioids and related peptides in stress-induced analgesia
-
Akil, H., Young, E., Walker, J.M. & Watson, S.J. (1986) The many possible roles of opioids and related peptides in stress-induced analgesia. Ann. NY Acad. Sci., 467, 140-153.
-
(1986)
Ann. NY Acad. Sci.
, vol.467
, pp. 140-153
-
-
Akil, H.1
Young, E.2
Walker, J.M.3
Watson, S.J.4
-
5
-
-
4344679320
-
An integrated study of heart pain and behavior in freely moving rats (using for as a marker for neuronal activation)
-
Albutaihi, I.A., DeJongste, M.J. & Ter Horst, G.J. (2004) An integrated study of heart pain and behavior in freely moving rats (using for as a marker for neuronal activation). Neurosignals, 13, 207-226.
-
(2004)
Neurosignals
, vol.13
, pp. 207-226
-
-
Albutaihi, I.A.1
DeJongste, M.J.2
Ter Horst, G.J.3
-
6
-
-
33746605204
-
The putative endocannabinoid transport blocker LY2183240 is a potent inhibitor of FAAH and several other brain serine hydrolases
-
Alexander, J.P. & Cravatt, B.F. (2006) The putative endocannabinoid transport blocker LY2183240 is a potent inhibitor of FAAH and several other brain serine hydrolases. J. Am. Chem. Soc., 128, 9699-9704.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 9699-9704
-
-
Alexander, J.P.1
Cravatt, B.F.2
-
7
-
-
80053501638
-
The role of endocannabinoids in pain modulation and the therapeutic potential of inhibiting their enzymatic degradation
-
Alvarez-Jaimes, L.J. & Palmer, J.A. (2011) The role of endocannabinoids in pain modulation and the therapeutic potential of inhibiting their enzymatic degradation. Curr. Pharm. Biotechno., 12, 1644-1659.
-
(2011)
Curr. Pharm. Biotechno.
, vol.12
, pp. 1644-1659
-
-
Alvarez-Jaimes, L.J.1
Palmer, J.A.2
-
8
-
-
0022975114
-
Stress-induced analgesia: adaptive pain suppression
-
Amit, Z. & Galina, Z.H. (1986) Stress-induced analgesia: adaptive pain suppression. Physiol. Rev., 66, 1091-1120.
-
(1986)
Physiol. Rev.
, vol.66
, pp. 1091-1120
-
-
Amit, Z.1
Galina, Z.H.2
-
9
-
-
77952623444
-
CB2: a cannabinoid receptor with an identity crisis
-
Atwood, B.K. & Mackie, K. (2010) CB2: a cannabinoid receptor with an identity crisis. Brit. J. Pharmacol., 160, 467-479.
-
(2010)
Brit. J. Pharmacol.
, vol.160
, pp. 467-479
-
-
Atwood, B.K.1
Mackie, K.2
-
10
-
-
79551586474
-
Intra-periaqueductal gray matter microinjection of orexin-A decreases formalin-induced nociceptive behaviors in adult male rats
-
Azhdari Zarmehri, H., Semnanian, S., Fathollahi, Y., Erami, E., Khakpay, R., Azizi, H. & Rohampour, K. (2011) Intra-periaqueductal gray matter microinjection of orexin-A decreases formalin-induced nociceptive behaviors in adult male rats. J. Pain, 12, 280-287.
-
(2011)
J. Pain
, vol.12
, pp. 280-287
-
-
Azhdari Zarmehri, H.1
Semnanian, S.2
Fathollahi, Y.3
Erami, E.4
Khakpay, R.5
Azizi, H.6
Rohampour, K.7
-
11
-
-
0028101302
-
Columnar organization in the midbrain periaqueductal gray: modules for emotional expression?
-
Bandler, R. & Shipley, M.T. (1994) Columnar organization in the midbrain periaqueductal gray: modules for emotional expression? Trends Neurosci., 17, 379-389.
-
(1994)
Trends Neurosci.
, vol.17
, pp. 379-389
-
-
Bandler, R.1
Shipley, M.T.2
-
12
-
-
0034685843
-
Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat
-
Beaulieu, P., Bisogno, T., Punwar, S., Farquhar-Smith, W.P., Ambrosino, G., Di Marzo, V. & Rice, A.S. (2000) Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat. Eur. J. Pharmacol., 396, 85-92.
-
(2000)
Eur. J. Pharmacol.
, vol.396
, pp. 85-92
-
-
Beaulieu, P.1
Bisogno, T.2
Punwar, S.3
Farquhar-Smith, W.P.4
Ambrosino, G.5
Di Marzo, V.6
Rice, A.S.7
-
13
-
-
0030865871
-
Functional role of high-affinity anandamide transport, as revealed by selective inhibition
-
Beltramo, M., Stella, N., Calignano, A., Lin, S.Y., Makriyannis, A. & Piomelli, D. (1997) Functional role of high-affinity anandamide transport, as revealed by selective inhibition. Science, 277, 1094-1097.
-
(1997)
Science
, vol.277
, pp. 1094-1097
-
-
Beltramo, M.1
Stella, N.2
Calignano, A.3
Lin, S.Y.4
Makriyannis, A.5
Piomelli, D.6
-
14
-
-
84874549162
-
Pain as a reward: changing the meaning of pain from negative to positive co-activates opioid and cannabinoid systems
-
Benedetti, F., Thoen, W., Blanchard, C., Vighetti, S. & Arduino, C. (2013) Pain as a reward: changing the meaning of pain from negative to positive co-activates opioid and cannabinoid systems. Pain, 154, 361-367.
-
(2013)
Pain
, vol.154
, pp. 361-367
-
-
Benedetti, F.1
Thoen, W.2
Blanchard, C.3
Vighetti, S.4
Arduino, C.5
-
15
-
-
36949026887
-
CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus
-
Bequet, F., Uzabiaga, F., Desbazeille, M., Ludwiczak, P., Maftouh, M., Picard, C., Scatton, B. & Le Fur, G. (2007) CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. Eur. J. Neurosci., 26, 3458-3464.
-
(2007)
Eur. J. Neurosci.
, vol.26
, pp. 3458-3464
-
-
Bequet, F.1
Uzabiaga, F.2
Desbazeille, M.3
Ludwiczak, P.4
Maftouh, M.5
Picard, C.6
Scatton, B.7
Le Fur, G.8
-
16
-
-
0033955355
-
Brainstem and hypothalamic areas involved in respiratory chemoreflexes: a Fos study in adult rats
-
Berquin, P., Bodineau, L., Gros, F. & Larnicol, N. (2000) Brainstem and hypothalamic areas involved in respiratory chemoreflexes: a Fos study in adult rats. Brain Res., 857, 30-40.
-
(2000)
Brain Res.
, vol.857
, pp. 30-40
-
-
Berquin, P.1
Bodineau, L.2
Gros, F.3
Larnicol, N.4
-
17
-
-
10744229235
-
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain
-
Bisogno, T., Howell, F., Williams, G., Minassi, A., Cascio, M.G., Ligresti, A., Matias, I., Schiano-Moriello, A., Paul, P., Williams, E.J., Gangadharan, U., Hobbs, C., Di Marzo, V. & Doherty, P. (2003) Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J. Cell Biol., 163, 463-468.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 463-468
-
-
Bisogno, T.1
Howell, F.2
Williams, G.3
Minassi, A.4
Cascio, M.G.5
Ligresti, A.6
Matias, I.7
Schiano-Moriello, A.8
Paul, P.9
Williams, E.J.10
Gangadharan, U.11
Hobbs, C.12
Di Marzo, V.13
Doherty, P.14
-
18
-
-
37149013708
-
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol
-
Blankman, J.L., Simon, G.M. & Cravatt, B.F. (2007) A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. Chem. Biol., 14, 1347-1356.
-
(2007)
Chem. Biol.
, vol.14
, pp. 1347-1356
-
-
Blankman, J.L.1
Simon, G.M.2
Cravatt, B.F.3
-
19
-
-
0017367697
-
9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine
-
Bloom, A.S., Dewey, W.L., Harris, L.S. & Brosius, K.K. (1977) 9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine. J. Pharmacol. Exp. Ther., 200, 263-270.
-
(1977)
J. Pharmacol. Exp. Ther.
, vol.200
, pp. 263-270
-
-
Bloom, A.S.1
Dewey, W.L.2
Harris, L.S.3
Brosius, K.K.4
-
20
-
-
84859051245
-
The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice
-
Booker, L., Kinsey, S.G., Abdullah, R.A., Blankman, J.L., Long, J.Z., Ezzili, C., Boger, D.L., Cravatt, B.F. & Lichtman, A.H. (2012) The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. Brit. J. Pharmacol., 165, 2485-2496.
-
(2012)
Brit. J. Pharmacol.
, vol.165
, pp. 2485-2496
-
-
Booker, L.1
Kinsey, S.G.2
Abdullah, R.A.3
Blankman, J.L.4
Long, J.Z.5
Ezzili, C.6
Boger, D.L.7
Cravatt, B.F.8
Lichtman, A.H.9
-
21
-
-
80051473369
-
Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses
-
Busquets-Garcia, A., Puighermanal, E., Pastor, A., de la Torre, R., Maldonado, R. & Ozaita, A. (2011) Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses. Biol. Psychiat., 70, 479-486.
-
(2011)
Biol. Psychiat.
, vol.70
, pp. 479-486
-
-
Busquets-Garcia, A.1
Puighermanal, E.2
Pastor, A.3
de la Torre, R.4
Maldonado, R.5
Ozaita, A.6
-
22
-
-
84856501971
-
Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase
-
Butler, R.K., Ford, G.K., Hogan, M., Roche, M., Doyle, K.M., Kelly, J.P., Kendall, D.A., Chapman, V. & Finn, D.P. (2012) Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase. J. Psychopharmacol., 26, 83-91.
-
(2012)
J. Psychopharmacol.
, vol.26
, pp. 83-91
-
-
Butler, R.K.1
Ford, G.K.2
Hogan, M.3
Roche, M.4
Doyle, K.M.5
Kelly, J.P.6
Kendall, D.A.7
Chapman, V.8
Finn, D.P.9
-
23
-
-
34147137062
-
Specific alterations of extracellular endocannabinoid levels in the nucleus accumbens by ethanol, heroin, and cocaine self-administration
-
Caille, S., Alvarez-Jaimes, L., Polis, I., Stouffer, D.G. & Parsons, L.H. (2007) Specific alterations of extracellular endocannabinoid levels in the nucleus accumbens by ethanol, heroin, and cocaine self-administration. J. Neurosci., 27, 3695-3702.
-
(2007)
J. Neurosci.
, vol.27
, pp. 3695-3702
-
-
Caille, S.1
Alvarez-Jaimes, L.2
Polis, I.3
Stouffer, D.G.4
Parsons, L.H.5
-
24
-
-
0032537734
-
Control of pain initiation by endogenous cannabinoids
-
Calignano, A., La Rana, G., Giuffrida, A. & Piomelli, D. (1998) Control of pain initiation by endogenous cannabinoids. Nature, 394, 277-281.
-
(1998)
Nature
, vol.394
, pp. 277-281
-
-
Calignano, A.1
La Rana, G.2
Giuffrida, A.3
Piomelli, D.4
-
25
-
-
78649924956
-
Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system
-
Chanda, P.K., Gao, Y., Mark, L., Btesh, J., Strassle, B.W., Lu, P., Piesla, M.J., Zhang, M.Y., Bingham, B., Uveges, A., Kowal, D., Garbe, D., Kouranova, E.V., Ring, R.H., Bates, B., Pangalos, M.N., Kennedy, J.D., Whiteside, G.T. & Samad, T.A. (2010) Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system. Mol. Pharmacol., 78, 996-1003.
-
(2010)
Mol. Pharmacol.
, vol.78
, pp. 996-1003
-
-
Chanda, P.K.1
Gao, Y.2
Mark, L.3
Btesh, J.4
Strassle, B.W.5
Lu, P.6
Piesla, M.J.7
Zhang, M.Y.8
Bingham, B.9
Uveges, A.10
Kowal, D.11
Garbe, D.12
Kouranova, E.V.13
Ring, R.H.14
Bates, B.15
Pangalos, M.N.16
Kennedy, J.D.17
Whiteside, G.T.18
Samad, T.A.19
-
26
-
-
0032588146
-
The cannabinoid CB1 receptor antagonist, SR141716A, selectively facilitates nociceptive responses of dorsal horn neurones in the rat
-
Chapman, V. (1999) The cannabinoid CB1 receptor antagonist, SR141716A, selectively facilitates nociceptive responses of dorsal horn neurones in the rat. Brit. J. Pharmacol., 127, 1765-1767.
-
(1999)
Brit. J. Pharmacol.
, vol.127
, pp. 1765-1767
-
-
Chapman, V.1
-
27
-
-
0031864742
-
CCK(B) receptors in the periaqueductal grey are involved in electroacupuncture antinociception in the rat cold water tail-flick test
-
Chen, X.H., Geller, E.B. & Adler, M.W. (1998) CCK(B) receptors in the periaqueductal grey are involved in electroacupuncture antinociception in the rat cold water tail-flick test. Neuropharmacology, 37, 751-757.
-
(1998)
Neuropharmacology
, vol.37
, pp. 751-757
-
-
Chen, X.H.1
Geller, E.B.2
Adler, M.W.3
-
28
-
-
78649899402
-
Orexins/hypocretins: pain regulation and cellular actions
-
Chiou, L.C., Lee, H.J., Ho, Y.C., Chen, S.P., Liao, Y.Y., Ma, C.H., Fan, P.C., Fuh, J.L. & Wang, S.J. (2010a) Orexins/hypocretins: pain regulation and cellular actions. Curr. Pharm. Design, 16, 3089-3100.
-
(2010)
Curr. Pharm. Design
, vol.16
, pp. 3089-3100
-
-
Chiou, L.C.1
Lee, H.J.2
Ho, Y.C.3
Chen, S.P.4
Liao, Y.Y.5
Ma, C.H.6
Fan, P.C.7
Fuh, J.L.8
Wang, S.J.9
-
29
-
-
84893349638
-
-
Restraint stress induces analgesia through endogenous orexins via OX1 receptor-mediated endocannabinoid retrograde disinhibition in the ventrolateral periaqueductal gray. In Neuroscience 2010, Prog. No. 844.1. San Diego, USA.
-
Chiou, L.C., Teng, S.F. & Chang, L.Y. (2010b) Restraint stress induces analgesia through endogenous orexins via OX1 receptor-mediated endocannabinoid retrograde disinhibition in the ventrolateral periaqueductal gray. In Neuroscience 2010, Prog. No. 844.1. San Diego, USA.
-
(2010)
-
-
Chiou, L.C.1
Teng, S.F.2
Chang, L.Y.3
-
30
-
-
0036221971
-
CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
-
Clayton, N., Marshall, F.H., Bountra, C. & O'Shaughnessy, C.T. (2002) CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain. Pain, 96, 253-260.
-
(2002)
Pain
, vol.96
, pp. 253-260
-
-
Clayton, N.1
Marshall, F.H.2
Bountra, C.3
O'Shaughnessy, C.T.4
-
31
-
-
0030995878
-
Pharmacology and functions of metabotropic glutamate receptors
-
Conn, P.J. & Pin, J.P. (1997) Pharmacology and functions of metabotropic glutamate receptors. Annu. Rev. Pharmacol., 37, 205-237.
-
(1997)
Annu. Rev. Pharmacol.
, vol.37
, pp. 205-237
-
-
Conn, P.J.1
Pin, J.P.2
-
32
-
-
0032777297
-
SR141716A induces in rats a behavioral pattern opposite to that of CB1 receptor agonists
-
Costa, B. & Colleoni, M. (1999) SR141716A induces in rats a behavioral pattern opposite to that of CB1 receptor agonists. Zhongguo Yao Li Xue Bao, 20, 1103-1108.
-
(1999)
Zhongguo Yao Li Xue Bao
, vol.20
, pp. 1103-1108
-
-
Costa, B.1
Colleoni, M.2
-
33
-
-
4644372326
-
The endogenous cannabinoid system and its role in nociceptive behavior
-
Cravatt, B.F. & Lichtman, A.H. (2004) The endogenous cannabinoid system and its role in nociceptive behavior. J. Neurobiol., 61, 149-160.
-
(2004)
J. Neurobiol.
, vol.61
, pp. 149-160
-
-
Cravatt, B.F.1
Lichtman, A.H.2
-
34
-
-
0035979244
-
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
-
Cravatt, B.F., Demarest, K., Patricelli, M.P., Bracey, M.H., Giang, D.K., Martin, B.R. & Lichtman, A.H. (2001) Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proc. Natl. Acad. Sci. USA, 98, 9371-9376.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9371-9376
-
-
Cravatt, B.F.1
Demarest, K.2
Patricelli, M.P.3
Bracey, M.H.4
Giang, D.K.5
Martin, B.R.6
Lichtman, A.H.7
-
35
-
-
3242710172
-
Functional disassociation of the central and peripheral fatty acid amide signaling systems
-
Cravatt, B.F., Saghatelian, A., Hawkins, E.G., Clement, A.B., Bracey, M.H. & Lichtman, A.H. (2004) Functional disassociation of the central and peripheral fatty acid amide signaling systems. Proc. Natl. Acad. Sci. USA, 101, 10821-10826.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10821-10826
-
-
Cravatt, B.F.1
Saghatelian, A.2
Hawkins, E.G.3
Clement, A.B.4
Bracey, M.H.5
Lichtman, A.H.6
-
36
-
-
0030152342
-
Endothelin-1 in periaqueductal gray area of mice induces analgesia via glutamatergic receptors
-
D'Amico, M., Berrino, L., Maione, S., Filippelli, A., de Novellis, V. & Rossi, F. (1996) Endothelin-1 in periaqueductal gray area of mice induces analgesia via glutamatergic receptors. Pain, 65, 205-209.
-
(1996)
Pain
, vol.65
, pp. 205-209
-
-
D'Amico, M.1
Berrino, L.2
Maione, S.3
Filippelli, A.4
de Novellis, V.5
Rossi, F.6
-
37
-
-
0035918311
-
The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism
-
De Petrocellis, L., Bisogno, T., Maccarrone, M., Davis, J.B., Finazzi-Agro, A. & Di Marzo, V. (2001) The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism. J. Biol. Chem., 276, 12856-12863.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12856-12863
-
-
De Petrocellis, L.1
Bisogno, T.2
Maccarrone, M.3
Davis, J.B.4
Finazzi-Agro, A.5
Di Marzo, V.6
-
38
-
-
0023469731
-
GABAergic modulation of the analgesic effects of morphine microinjected in the ventral periaqueductal gray matter of the rat
-
Depaulis, A., Morgan, M.M. & Liebeskind, J.C. (1987) GABAergic modulation of the analgesic effects of morphine microinjected in the ventral periaqueductal gray matter of the rat. Brain Res., 436, 223-228.
-
(1987)
Brain Res.
, vol.436
, pp. 223-228
-
-
Depaulis, A.1
Morgan, M.M.2
Liebeskind, J.C.3
-
39
-
-
57349137829
-
Modulation of the anti-nociceptive effects of 2-arachidonoyl glycerol by peripherally administered FAAH and MGL inhibitors in a neuropathic pain model
-
Desroches, J., Guindon, J., Lambert, C. & Beaulieu, P. (2008) Modulation of the anti-nociceptive effects of 2-arachidonoyl glycerol by peripherally administered FAAH and MGL inhibitors in a neuropathic pain model. Brit. J. Pharmacol., 155, 913-924.
-
(2008)
Brit. J. Pharmacol.
, vol.155
, pp. 913-924
-
-
Desroches, J.1
Guindon, J.2
Lambert, C.3
Beaulieu, P.4
-
40
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane, W.A., Hanus, L., Breuer, A., Pertwee, R.G., Stevenson, L.A., Griffin, G., Gibson, D., Mandelbaum, A., Etinger, A. & Mechoulam, R. (1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science, 258, 1946-1949.
-
(1992)
Science
, vol.258
, pp. 1946-1949
-
-
Devane, W.A.1
Hanus, L.2
Breuer, A.3
Pertwee, R.G.4
Stevenson, L.A.5
Griffin, G.6
Gibson, D.7
Mandelbaum, A.8
Etinger, A.9
Mechoulam, R.10
-
41
-
-
48249097797
-
Endocannabinoids: synthesis and degradation
-
Di Marzo, V. (2008) Endocannabinoids: synthesis and degradation. Rev. Physiol. Bioch. P., 160, 1-24.
-
(2008)
Rev. Physiol. Bioch. P.
, vol.160
, pp. 1-24
-
-
Di Marzo, V.1
-
42
-
-
84864624995
-
Inhibitors of endocannabinoid breakdown for pain: not so FA(AH)cile, after all
-
Di Marzo, V. (2012) Inhibitors of endocannabinoid breakdown for pain: not so FA(AH)cile, after all. Pain, 153, 1785-1786.
-
(2012)
Pain
, vol.153
, pp. 1785-1786
-
-
Di Marzo, V.1
-
43
-
-
17844388556
-
Endocannabinoid control of food intake and energy balance
-
Di Marzo, V. & Matias, I. (2005) Endocannabinoid control of food intake and energy balance. Nat. Neurosci., 8, 585-589.
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 585-589
-
-
Di Marzo, V.1
Matias, I.2
-
44
-
-
0028589390
-
Formation and inactivation of endogenous cannabinoid anandamide in central neurons
-
Di Marzo, V., Fontana, A., Cadas, H., Schinelli, S., Cimino, G., Schwartz, J.C. & Piomelli, D. (1994) Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature, 372, 686-691.
-
(1994)
Nature
, vol.372
, pp. 686-691
-
-
Di Marzo, V.1
Fontana, A.2
Cadas, H.3
Schinelli, S.4
Cimino, G.5
Schwartz, J.C.6
Piomelli, D.7
-
45
-
-
0032055496
-
The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide
-
Di Marzo, V., Bisogno, T., Sugiura, T., Melck, D. & De Petrocellis, L. (1998) The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide. Biochem. J., 331(Pt 1), 15-19.
-
(1998)
Biochem. J.
, vol.331
, Issue.PT 1
, pp. 15-19
-
-
Di Marzo, V.1
Bisogno, T.2
Sugiura, T.3
Melck, D.4
De Petrocellis, L.5
-
46
-
-
0035397895
-
Anandamide: some like it hot
-
Di Marzo, V., Bisogno, T. & De Petrocellis, L. (2001) Anandamide: some like it hot. Trends Pharmacol. Sci., 22, 346-349.
-
(2001)
Trends Pharmacol. Sci.
, vol.22
, pp. 346-349
-
-
Di Marzo, V.1
Bisogno, T.2
De Petrocellis, L.3
-
47
-
-
4544275181
-
The endocannabinoid system and its therapeutic exploitation
-
Di Marzo, V., Bifulco, M. & De Petrocellis, L. (2004) The endocannabinoid system and its therapeutic exploitation. Nat. Rev. Drug Discov., 3, 771-784.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 771-784
-
-
Di Marzo, V.1
Bifulco, M.2
De Petrocellis, L.3
-
48
-
-
0037207088
-
A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation
-
Dinh, T.P., Freund, T.F. & Piomelli, D. (2002) A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation. Chem. Phys. Lipids, 121, 149-158.
-
(2002)
Chem. Phys. Lipids
, vol.121
, pp. 149-158
-
-
Dinh, T.P.1
Freund, T.F.2
Piomelli, D.3
-
49
-
-
6944247598
-
RNA interference suggests a primary role for monoacylglycerol lipase in the degradation of the endocannabinoid 2-arachidonoylglycerol
-
Dinh, T.P., Kathuria, S. & Piomelli, D. (2004) RNA interference suggests a primary role for monoacylglycerol lipase in the degradation of the endocannabinoid 2-arachidonoylglycerol. Mol. Pharmacol., 66, 1260-1264.
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 1260-1264
-
-
Dinh, T.P.1
Kathuria, S.2
Piomelli, D.3
-
50
-
-
0036844373
-
'Knock-down' of spinal CB1 receptors produces abnormal pain and elevates spinal dynorphin content in mice
-
Dogrul, A., Gardell, L.R., Ma, S., Ossipov, M.H., Porreca, F. & Lai, J. (2002) 'Knock-down' of spinal CB1 receptors produces abnormal pain and elevates spinal dynorphin content in mice. Pain, 100, 203-209.
-
(2002)
Pain
, vol.100
, pp. 203-209
-
-
Dogrul, A.1
Gardell, L.R.2
Ma, S.3
Ossipov, M.H.4
Porreca, F.5
Lai, J.6
-
51
-
-
1842714365
-
Multiple metabotropic glutamate receptor subtypes modulate GABAergic neurotransmission in rat periaqueductal grey neurons in vitro
-
Drew, G.M. & Vaughan, C.W. (2004) Multiple metabotropic glutamate receptor subtypes modulate GABAergic neurotransmission in rat periaqueductal grey neurons in vitro. Neuropharmacology, 46, 927-934.
-
(2004)
Neuropharmacology
, vol.46
, pp. 927-934
-
-
Drew, G.M.1
Vaughan, C.W.2
-
52
-
-
38549118811
-
Glutamate spillover modulates GABAergic synaptic transmission in the rat midbrain periaqueductal grey via metabotropic glutamate receptors and endocannabinoid signaling
-
Drew, G.M., Mitchell, V.A. & Vaughan, C.W. (2008) Glutamate spillover modulates GABAergic synaptic transmission in the rat midbrain periaqueductal grey via metabotropic glutamate receptors and endocannabinoid signaling. J. Neurosci., 28, 808-815.
-
(2008)
J. Neurosci.
, vol.28
, pp. 808-815
-
-
Drew, G.M.1
Mitchell, V.A.2
Vaughan, C.W.3
-
53
-
-
66749083837
-
Substance P drives endocannabinoid-mediated disinhibition in a midbrain descending analgesic pathway
-
Drew, G.M., Lau, B.K. & Vaughan, C.W. (2009) Substance P drives endocannabinoid-mediated disinhibition in a midbrain descending analgesic pathway. J. Neurosci., 29, 7220-7229.
-
(2009)
J. Neurosci.
, vol.29
, pp. 7220-7229
-
-
Drew, G.M.1
Lau, B.K.2
Vaughan, C.W.3
-
54
-
-
0032494704
-
A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain
-
Egertova, M., Giang, D.K., Cravatt, B.F. & Elphick, M.R. (1998) A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain. Proc. Biol. Sci., 265, 2081-2085.
-
(1998)
Proc. Biol. Sci.
, vol.265
, pp. 2081-2085
-
-
Egertova, M.1
Giang, D.K.2
Cravatt, B.F.3
Elphick, M.R.4
-
55
-
-
0038738350
-
Comparative analysis of fatty acid amide hydrolase and cb(1) cannabinoid receptor expression in the mouse brain: evidence of a widespread role for fatty acid amide hydrolase in regulation of endocannabinoid signaling
-
Egertova, M., Cravatt, B.F. & Elphick, M.R. (2003) Comparative analysis of fatty acid amide hydrolase and cb(1) cannabinoid receptor expression in the mouse brain: evidence of a widespread role for fatty acid amide hydrolase in regulation of endocannabinoid signaling. Neuroscience, 119, 481-496.
-
(2003)
Neuroscience
, vol.119
, pp. 481-496
-
-
Egertova, M.1
Cravatt, B.F.2
Elphick, M.R.3
-
56
-
-
5044236417
-
Fatty acid amide hydrolase in brain ventricular epithelium: mutually exclusive patterns of expression in mouse and rat
-
Egertova, M., Michael, G.J., Cravatt, B.F. & Elphick, M.R. (2004) Fatty acid amide hydrolase in brain ventricular epithelium: mutually exclusive patterns of expression in mouse and rat. J. Chem. Neuroanat., 28, 171-181.
-
(2004)
J. Chem. Neuroanat.
, vol.28
, pp. 171-181
-
-
Egertova, M.1
Michael, G.J.2
Cravatt, B.F.3
Elphick, M.R.4
-
57
-
-
14844323722
-
Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors
-
Farrant, M. & Nusser, Z. (2005) Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors. Nat. Rev. Neurosci., 6, 215-229.
-
(2005)
Nat. Rev. Neurosci.
, vol.6
, pp. 215-229
-
-
Farrant, M.1
Nusser, Z.2
-
58
-
-
0030278184
-
Stress-induced analgesia. The role of hormones produced by the hypophyseal-adrenocortical system
-
Filaretov, A.A., Bogdanov, A.I. & Yarushkina, N.I. (1996) Stress-induced analgesia. The role of hormones produced by the hypophyseal-adrenocortical system. Neurosci. Behav. Physiol., 26, 572-578.
-
(1996)
Neurosci. Behav. Physiol.
, vol.26
, pp. 572-578
-
-
Filaretov, A.A.1
Bogdanov, A.I.2
Yarushkina, N.I.3
-
59
-
-
3843083058
-
Evidence for differential modulation of conditioned aversion and fear-conditioned analgesia by CB1 receptors
-
Finn, D.P., Beckett, S.R., Richardson, D., Kendall, D.A., Marsden, C.A. & Chapman, V. (2004) Evidence for differential modulation of conditioned aversion and fear-conditioned analgesia by CB1 receptors. Eur. J. Neurosci., 20, 848-852.
-
(2004)
Eur. J. Neurosci.
, vol.20
, pp. 848-852
-
-
Finn, D.P.1
Beckett, S.R.2
Richardson, D.3
Kendall, D.A.4
Marsden, C.A.5
Chapman, V.6
-
60
-
-
0036379225
-
Pavlovian conditioning of opioid and nonopioid pain inhibitory mechanisms in humans
-
Flor, H., Birbaumer, N., Schulz, R., Grusser, S.M. & Mucha, R.F. (2002) Pavlovian conditioning of opioid and nonopioid pain inhibitory mechanisms in humans. Eur. J. Pain, 6, 395-402.
-
(2002)
Eur. J. Pain
, vol.6
, pp. 395-402
-
-
Flor, H.1
Birbaumer, N.2
Schulz, R.3
Grusser, S.M.4
Mucha, R.F.5
-
61
-
-
84876947593
-
Transport of endocannabinoids across the plasma membrane and within the cell
-
Fowler, C.J. (2013) Transport of endocannabinoids across the plasma membrane and within the cell. FEBS J., 280, 1895-1904.
-
(2013)
FEBS J.
, vol.280
, pp. 1895-1904
-
-
Fowler, C.J.1
-
62
-
-
0037904681
-
Excitement reduces inhibition via endocannabinoids
-
Freund, T.F. & Hajos, N. (2003) Excitement reduces inhibition via endocannabinoids. Neuron, 38, 362-365.
-
(2003)
Neuron
, vol.38
, pp. 362-365
-
-
Freund, T.F.1
Hajos, N.2
-
63
-
-
0029094470
-
Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations
-
Galiegue, S., Mary, S., Marchand, J., Dussossoy, D., Carriere, D., Carayon, P., Bouaboula, M., Shire, D., Le Fur, G. & Casellas, P. (1995) Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations. Eur. J. Biochem., 232, 54-61.
-
(1995)
Eur. J. Biochem.
, vol.232
, pp. 54-61
-
-
Galiegue, S.1
Mary, S.2
Marchand, J.3
Dussossoy, D.4
Carriere, D.5
Carayon, P.6
Bouaboula, M.7
Shire, D.8
Le Fur, G.9
Casellas, P.10
-
64
-
-
76649137560
-
Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice
-
Gao, Y., Vasilyev, D.V., Goncalves, M.B., Howell, F.V., Hobbs, C., Reisenberg, M., Shen, R., Zhang, M.Y., Strassle, B.W., Lu, P., Mark, L., Piesla, M.J., Deng, K., Kouranova, E.V., Ring, R.H., Whiteside, G.T., Bates, B., Walsh, F.S., Williams, G., Pangalos, M.N., Samad, T.A. & Doherty, P. (2010) Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice. J. Neurosci., 30, 2017-2024.
-
(2010)
J. Neurosci.
, vol.30
, pp. 2017-2024
-
-
Gao, Y.1
Vasilyev, D.V.2
Goncalves, M.B.3
Howell, F.V.4
Hobbs, C.5
Reisenberg, M.6
Shen, R.7
Zhang, M.Y.8
Strassle, B.W.9
Lu, P.10
Mark, L.11
Piesla, M.J.12
Deng, K.13
Kouranova, E.V.14
Ring, R.H.15
Whiteside, G.T.16
Bates, B.17
Walsh, F.S.18
Williams, G.19
Pangalos, M.N.20
Samad, T.A.21
Doherty, P.22
more..
-
65
-
-
33947489961
-
Isolation, structure and partial synthesis of an active constituent of hashish
-
Gaoni, Y. & Mechoulam, R. (1964) Isolation, structure and partial synthesis of an active constituent of hashish. J. Am. Chem. Soc., 86, 1646-1647.
-
(1964)
J. Am. Chem. Soc.
, vol.86
, pp. 1646-1647
-
-
Gaoni, Y.1
Mechoulam, R.2
-
66
-
-
0025878961
-
Molecular cloning of a human cannabinoid receptor which is also expressed in testis
-
Gerard, C.M., Mollereau, C., Vassart, G. & Parmentier, M. (1991) Molecular cloning of a human cannabinoid receptor which is also expressed in testis. Biochem. J., 279(Pt 1), 129-134.
-
(1991)
Biochem. J.
, vol.279
, Issue.PT 1
, pp. 129-134
-
-
Gerard, C.M.1
Mollereau, C.2
Vassart, G.3
Parmentier, M.4
-
67
-
-
48249115990
-
Beta-caryophyllene is a dietary cannabinoid
-
Gertsch, J., Leonti, M., Raduner, S., Racz, I., Chen, J.Z., Xie, X.Q., Altmann, K.H., Karsak, M. & Zimmer, A. (2008) Beta-caryophyllene is a dietary cannabinoid. Proc. Natl. Acad. Sci. USA, 105, 9099-9104.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 9099-9104
-
-
Gertsch, J.1
Leonti, M.2
Raduner, S.3
Racz, I.4
Chen, J.Z.5
Xie, X.Q.6
Altmann, K.H.7
Karsak, M.8
Zimmer, A.9
-
68
-
-
84874649914
-
The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model
-
Ghosh, S., Wise, L.E., Chen, Y., Gujjar, R., Mahadevan, A., Cravatt, B.F. & Lichtman, A.H. (2013) The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model. Life Sci., 92, 498-505.
-
(2013)
Life Sci.
, vol.92
, pp. 498-505
-
-
Ghosh, S.1
Wise, L.E.2
Chen, Y.3
Gujjar, R.4
Mahadevan, A.5
Cravatt, B.F.6
Lichtman, A.H.7
-
69
-
-
23044479980
-
Anandamide transport: a critical review
-
Glaser, S.T., Kaczocha, M. & Deutsch, D.G. (2005) Anandamide transport: a critical review. Life Sci., 77, 1584-1604.
-
(2005)
Life Sci.
, vol.77
, pp. 1584-1604
-
-
Glaser, S.T.1
Kaczocha, M.2
Deutsch, D.G.3
-
70
-
-
0034058250
-
Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide
-
Gonsiorek, W., Lunn, C., Fan, X., Narula, S., Lundell, D. & Hipkin, R.W. (2000) Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide. Mol. Pharmacol., 57, 1045-1050.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 1045-1050
-
-
Gonsiorek, W.1
Lunn, C.2
Fan, X.3
Narula, S.4
Lundell, D.5
Hipkin, R.W.6
-
71
-
-
0032898720
-
Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors
-
Goparaju, S.K., Ueda, N., Taniguchi, K. & Yamamoto, S. (1999) Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors. Biochem. Pharmacol., 57, 417-423.
-
(1999)
Biochem. Pharmacol.
, vol.57
, pp. 417-423
-
-
Goparaju, S.K.1
Ueda, N.2
Taniguchi, K.3
Yamamoto, S.4
-
72
-
-
84872812654
-
Contribution of genetic variants to pain susceptibility in Parkinson disease
-
Greenbaum, L., Tegeder, I., Barhum, Y., Melamed, E., Roditi, Y. & Djaldetti, R. (2012) Contribution of genetic variants to pain susceptibility in Parkinson disease. Eur. J. Pain, 16, 1243-1250.
-
(2012)
Eur. J. Pain
, vol.16
, pp. 1243-1250
-
-
Greenbaum, L.1
Tegeder, I.2
Barhum, Y.3
Melamed, E.4
Roditi, Y.5
Djaldetti, R.6
-
73
-
-
84863635267
-
Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-alpha initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia
-
Gregg, L.C., Jung, K.M., Spradley, J.M., Nyilas, R., Suplita, R.L. II., Zimmer, A., Watanabe, M., Mackie, K., Katona, I., Piomelli, D. & Hohmann, A.G. (2012) Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-alpha initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. J. Neurosci., 32, 9457-9468.
-
(2012)
J. Neurosci.
, vol.32
, pp. 9457-9468
-
-
Gregg, L.C.1
Jung, K.M.2
Spradley, J.M.3
Nyilas, R.4
Suplita II, R.L.5
Zimmer, A.6
Watanabe, M.7
Mackie, K.8
Katona, I.9
Piomelli, D.10
Hohmann, A.G.11
-
74
-
-
2942639913
-
Endogenous neurotensin facilitates visceral nociception and is required for stress-induced antinociception in mice and rats
-
Gui, X., Carraway, R.E. & Dobner, P.R. (2004) Endogenous neurotensin facilitates visceral nociception and is required for stress-induced antinociception in mice and rats. Neuroscience, 126, 1023-1032.
-
(2004)
Neuroscience
, vol.126
, pp. 1023-1032
-
-
Gui, X.1
Carraway, R.E.2
Dobner, P.R.3
-
75
-
-
0343091558
-
Modulation of carbachol-induced antinociception from the rat periaqueductal gray
-
Guimaraes, A.P., Guimaraes, F.S. & Prado, W.A. (2000) Modulation of carbachol-induced antinociception from the rat periaqueductal gray. Brain Res. Bull., 51, 471-478.
-
(2000)
Brain Res. Bull.
, vol.51
, pp. 471-478
-
-
Guimaraes, A.P.1
Guimaraes, F.S.2
Prado, W.A.3
-
76
-
-
84926231211
-
Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain
-
Guindon, J., Guijarro, A., Piomelli, D. & Hohmann, A.G. (2011) Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. Brit. J. Pharmacol., 163, 1464-1478.
-
(2011)
Brit. J. Pharmacol.
, vol.163
, pp. 1464-1478
-
-
Guindon, J.1
Guijarro, A.2
Piomelli, D.3
Hohmann, A.G.4
-
77
-
-
84870915147
-
Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment
-
Guindon, J., Lai, Y., Takacs, S.M., Bradshaw, H.B. & Hohmann, A.G. (2013) Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment. Pharmacol. Res., 67, 94-109.
-
(2013)
Pharmacol. Res.
, vol.67
, pp. 94-109
-
-
Guindon, J.1
Lai, Y.2
Takacs, S.M.3
Bradshaw, H.B.4
Hohmann, A.G.5
-
78
-
-
84857794906
-
Regulation of endocannabinoid release by G proteins: a paracrine mechanism of G protein-coupled receptor action
-
Gyombolai, P., Pap, D., Turu, G., Catt, K.J., Bagdy, G. & Hunyady, L. (2012) Regulation of endocannabinoid release by G proteins: a paracrine mechanism of G protein-coupled receptor action. Mol. Cell. Endocrinol., 353, 29-36.
-
(2012)
Mol. Cell. Endocrinol.
, vol.353
, pp. 29-36
-
-
Gyombolai, P.1
Pap, D.2
Turu, G.3
Catt, K.J.4
Bagdy, G.5
Hunyady, L.6
-
79
-
-
12844284453
-
The wake-promoting peptide orexin-B inhibits glutamatergic transmission to dorsal raphe nucleus serotonin neurons through retrograde endocannabinoid signaling
-
Haj-Dahmane, S. & Shen, R.Y. (2005) The wake-promoting peptide orexin-B inhibits glutamatergic transmission to dorsal raphe nucleus serotonin neurons through retrograde endocannabinoid signaling. J. Neurosci., 25, 896-905.
-
(2005)
J. Neurosci.
, vol.25
, pp. 896-905
-
-
Haj-Dahmane, S.1
Shen, R.Y.2
-
80
-
-
55949098666
-
Modulation of opioids via protection of anandamide degradation by fatty acid amide hydrolase
-
Haller, V.L., Stevens, D.L. & Welch, S.P. (2008) Modulation of opioids via protection of anandamide degradation by fatty acid amide hydrolase. Eur. J. Pharmacol., 600, 50-58.
-
(2008)
Eur. J. Pharmacol.
, vol.600
, pp. 50-58
-
-
Haller, V.L.1
Stevens, D.L.2
Welch, S.P.3
-
81
-
-
0035957425
-
2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor
-
Hanus, L., Abu-Lafi, S., Fride, E., Breuer, A., Vogel, Z., Shalev, D.E., Kustanovich, I. & Mechoulam, R. (2001) 2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor. Proc. Natl. Acad. Sci. USA, 98, 3662-3665.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3662-3665
-
-
Hanus, L.1
Abu-Lafi, S.2
Fride, E.3
Breuer, A.4
Vogel, Z.5
Shalev, D.E.6
Kustanovich, I.7
Mechoulam, R.8
-
82
-
-
48749116524
-
Effects of URB597 as an inhibitor of fatty acid amide hydrolase on modulation of nociception in a rat model of cholestasis
-
Hasanein, P., Shahidi, S., Komaki, A. & Mirazi, N. (2008) Effects of URB597 as an inhibitor of fatty acid amide hydrolase on modulation of nociception in a rat model of cholestasis. Eur. J. Pharmacol., 591, 132-135.
-
(2008)
Eur. J. Pharmacol.
, vol.591
, pp. 132-135
-
-
Hasanein, P.1
Shahidi, S.2
Komaki, A.3
Mirazi, N.4
-
83
-
-
12344311450
-
(2+) dependency for triggering retrograde endocannabinoid signal
-
(2+) dependency for triggering retrograde endocannabinoid signal. Neuron, 45, 257-268.
-
(2005)
Neuron
, vol.45
, pp. 257-268
-
-
Hashimotodani, Y.1
Ohno-Shosaku, T.2
Tsubokawa, H.3
Ogata, H.4
Emoto, K.5
Maejima, T.6
Araishi, K.7
Shin, H.S.8
Kano, M.9
-
84
-
-
34249936616
-
(2+) -assisted receptor-driven endocannabinoid release: mechanisms that associate presynaptic and postsynaptic activities
-
(2+) -assisted receptor-driven endocannabinoid release: mechanisms that associate presynaptic and postsynaptic activities. Curr. Opin. Neurobiol., 17, 360-365.
-
(2007)
Curr. Opin. Neurobiol.
, vol.17
, pp. 360-365
-
-
Hashimotodani, Y.1
Ohno-Shosaku, T.2
Kano, M.3
-
85
-
-
63449092750
-
Descending control of nociception: specificity, recruitment and plasticity
-
Heinricher, M.M., Tavares, I., Leith, J.L. & Lumb, B.M. (2009) Descending control of nociception: specificity, recruitment and plasticity. Brain Res. Rev., 60, 214-225.
-
(2009)
Brain Res. Rev.
, vol.60
, pp. 214-225
-
-
Heinricher, M.M.1
Tavares, I.2
Leith, J.L.3
Lumb, B.M.4
-
86
-
-
0025954862
-
Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study
-
Herkenham, M., Lynn, A.B., Johnson, M.R., Melvin, L.S., de Costa, B.R. & Rice, K.C. (1991) Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study. J. Neurosci., 11, 563-583.
-
(1991)
J. Neurosci.
, vol.11
, pp. 563-583
-
-
Herkenham, M.1
Lynn, A.B.2
Johnson, M.R.3
Melvin, L.S.4
de Costa, B.R.5
Rice, K.C.6
-
87
-
-
80054029943
-
Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition
-
Ho, Y.C., Lee, H.J., Tung, L.W., Liao, Y.Y., Fu, S.Y., Teng, S.F., Liao, H.T., Mackie, K. & Chiou, L.C. (2011) Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. J. Neurosci., 31, 14600-14610.
-
(2011)
J. Neurosci.
, vol.31
, pp. 14600-14610
-
-
Ho, Y.C.1
Lee, H.J.2
Tung, L.W.3
Liao, Y.Y.4
Fu, S.Y.5
Teng, S.F.6
Liao, H.T.7
Mackie, K.8
Chiou, L.C.9
-
88
-
-
0029070520
-
Inhibition of noxious stimulus-evoked activity of spinal cord dorsal horn neurons by the cannabinoid WIN 55,212-2
-
Hohmann, A.G., Martin, W.J., Tsou, K. & Walker, J.M. (1995) Inhibition of noxious stimulus-evoked activity of spinal cord dorsal horn neurons by the cannabinoid WIN 55, 212-2. Life Sci., 56, 2111-2118.
-
(1995)
Life Sci.
, vol.56
, pp. 2111-2118
-
-
Hohmann, A.G.1
Martin, W.J.2
Tsou, K.3
Walker, J.M.4
-
89
-
-
0033064793
-
Cannabinoid suppression of noxious heat-evoked activity in wide dynamic range neurons in the lumbar dorsal horn of the rat
-
Hohmann, A.G., Tsou, K. & Walker, J.M. (1999a) Cannabinoid suppression of noxious heat-evoked activity in wide dynamic range neurons in the lumbar dorsal horn of the rat. J. Neurophysiol., 81, 575-583.
-
(1999)
J. Neurophysiol.
, vol.81
, pp. 575-583
-
-
Hohmann, A.G.1
Tsou, K.2
Walker, J.M.3
-
90
-
-
13044258892
-
Intrathecal cannabinoid administration suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in rat spinal cord: comparison with morphine
-
Hohmann, A.G., Tsou, K. & Walker, J.M. (1999b) Intrathecal cannabinoid administration suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in rat spinal cord: comparison with morphine. Zhongguo Yao Li Xue Bao, 20, 1132-1136.
-
(1999)
Zhongguo Yao Li Xue Bao
, vol.20
, pp. 1132-1136
-
-
Hohmann, A.G.1
Tsou, K.2
Walker, J.M.3
-
91
-
-
21344444379
-
An endocannabinoid mechanism for stress-induced analgesia
-
Hohmann, A.G., Suplita, R.L., Bolton, N.M., Neely, M.H., Fegley, D., Mangieri, R., Krey, J.F., Walker, J.M., Holmes, P.V., Crystal, J.D., Duranti, A., Tontini, A., Mor, M., Tarzia, G. & Piomelli, D. (2005) An endocannabinoid mechanism for stress-induced analgesia. Nature, 435, 1108-1112.
-
(2005)
Nature
, vol.435
, pp. 1108-1112
-
-
Hohmann, A.G.1
Suplita, R.L.2
Bolton, N.M.3
Neely, M.H.4
Fegley, D.5
Mangieri, R.6
Krey, J.F.7
Walker, J.M.8
Holmes, P.V.9
Crystal, J.D.10
Duranti, A.11
Tontini, A.12
Mor, M.13
Tarzia, G.14
Piomelli, D.15
-
92
-
-
61449206997
-
An NK1 receptor antagonist microinjected into the periaqueductal gray blocks lateral hypothalamic-induced antinociception in rats
-
Holden, J.E., Pizzi, J.A. & Jeong, Y. (2009) An NK1 receptor antagonist microinjected into the periaqueductal gray blocks lateral hypothalamic-induced antinociception in rats. Neurosci. Lett., 453, 115-119.
-
(2009)
Neurosci. Lett.
, vol.453
, pp. 115-119
-
-
Holden, J.E.1
Pizzi, J.A.2
Jeong, Y.3
-
93
-
-
0033081871
-
Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: a novel circuit implicated in metabolic and endocrine regulations
-
Horvath, T.L., Diano, S. & van den Pol, A.N. (1999a) Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: a novel circuit implicated in metabolic and endocrine regulations. J. Neurosci., 19, 1072-1087.
-
(1999)
J. Neurosci.
, vol.19
, pp. 1072-1087
-
-
Horvath, T.L.1
Diano, S.2
van den Pol, A.N.3
-
94
-
-
0033552658
-
Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system
-
Horvath, T.L., Peyron, C., Diano, S., Ivanov, A., Aston-Jones, G., Kilduff, T.S. & van Den Pol, A.N. (1999b) Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system. J. Comp. Neurol., 415, 145-159.
-
(1999)
J. Comp. Neurol.
, vol.415
, pp. 145-159
-
-
Horvath, T.L.1
Peyron, C.2
Diano, S.3
Ivanov, A.4
Aston-Jones, G.5
Kilduff, T.S.6
van Den Pol, A.N.7
-
95
-
-
18444376760
-
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
-
Howlett, A.C., Barth, F., Bonner, T.I., Cabral, G., Casellas, P., Devane, W.A., Felder, C.C., Herkenham, M., Mackie, K., Martin, B.R., Mechoulam, R. & Pertwee, R.G. (2002) International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol. Rev., 54, 161-202.
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 161-202
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
Cabral, G.4
Casellas, P.5
Devane, W.A.6
Felder, C.C.7
Herkenham, M.8
Mackie, K.9
Martin, B.R.10
Mechoulam, R.11
Pertwee, R.G.12
-
96
-
-
4644331847
-
Cannabinoid physiology and pharmacology: 30 years of progress
-
Howlett, A.C., Breivogel, C.S., Childers, S.R., Deadwyler, S.A., Hampson, R.E. & Porrino, L.J. (2004) Cannabinoid physiology and pharmacology: 30 years of progress. Neuropharmacology, 47(Suppl 1), 345-358.
-
(2004)
Neuropharmacology
, vol.47
, Issue.SUPPL. 1
, pp. 345-358
-
-
Howlett, A.C.1
Breivogel, C.S.2
Childers, S.R.3
Deadwyler, S.A.4
Hampson, R.E.5
Porrino, L.J.6
-
97
-
-
0037062411
-
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
-
Huang, S.M., Bisogno, T., Trevisani, M., Al-Hayani, A., De Petrocellis, L., Fezza, F., Tognetto, M., Petros, T.J., Krey, J.F., Chu, C.J., Miller, J.D., Davies, S.N., Geppetti, P., Walker, J.M. & Di Marzo, V. (2002) An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc. Natl. Acad. Sci. USA, 99, 8400-8405.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8400-8405
-
-
Huang, S.M.1
Bisogno, T.2
Trevisani, M.3
Al-Hayani, A.4
De Petrocellis, L.5
Fezza, F.6
Tognetto, M.7
Petros, T.J.8
Krey, J.F.9
Chu, C.J.10
Miller, J.D.11
Davies, S.N.12
Geppetti, P.13
Walker, J.M.14
Di Marzo, V.15
-
98
-
-
84864577250
-
An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee
-
Huggins, J.P., Smart, T.S., Langman, S., Taylor, L. & Young, T. (2012) An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee. Pain, 153, 1837-1846.
-
(2012)
Pain
, vol.153
, pp. 1837-1846
-
-
Huggins, J.P.1
Smart, T.S.2
Langman, S.3
Taylor, L.4
Young, T.5
-
99
-
-
0041836218
-
Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS
-
Ibrahim, M.M., Deng, H., Zvonok, A., Cockayne, D.A., Kwan, J., Mata, H.P., Vanderah, T.W., Lai, J., Porreca, F., Makriyannis, A. & Malan, T.P. Jr. (2003) Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS. Proc. Natl. Acad. Sci. USA, 100, 10529-10533.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10529-10533
-
-
Ibrahim, M.M.1
Deng, H.2
Zvonok, A.3
Cockayne, D.A.4
Kwan, J.5
Mata, H.P.6
Vanderah, T.W.7
Lai, J.8
Porreca, F.9
Makriyannis, A.10
Malan Jr, T.P.11
-
100
-
-
33646062552
-
CB(2) cannabinoid receptor mediation of antinociception
-
Ibrahim, M.M., Rude, M.L., Stagg, N.J., Mata, H.P., Lai, J., Vanderah, T.W., Porreca, F., Buckley, N.E., Makriyannis, A. & Malan, T.P. Jr. (2006) CB(2) cannabinoid receptor mediation of antinociception. Pain, 122, 36-42.
-
(2006)
Pain
, vol.122
, pp. 36-42
-
-
Ibrahim, M.M.1
Rude, M.L.2
Stagg, N.J.3
Mata, H.P.4
Lai, J.5
Vanderah, T.W.6
Porreca, F.7
Buckley, N.E.8
Makriyannis, A.9
Malan Jr, T.P.10
-
101
-
-
84893349761
-
In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects
-
doi: 10.1111/bph.12298. [Epub ahead of print].
-
Ignatowska-Jankowska, B.M., Ghosh, S., Crowe, M.S., Kinsey, S.G., Niphakis, M.J., Abdullah, R.A., Tao, Q., O'Neal, S.T., Walentiny, D.M., Wiley, J.L., Cravatt, B.F. & Lichtman, A.H. (2013) In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects. Brit. J. Pharmacol., doi: 10.1111/bph.12298. [Epub ahead of print].
-
(2013)
Brit. J. Pharmacol.
-
-
Ignatowska-Jankowska, B.M.1
Ghosh, S.2
Crowe, M.S.3
Kinsey, S.G.4
Niphakis, M.J.5
Abdullah, R.A.6
Tao, Q.7
O'Neal, S.T.8
Walentiny, D.M.9
Wiley, J.L.10
Cravatt, B.F.11
Lichtman, A.H.12
-
102
-
-
0028272375
-
Facilitation of the arterial baroreflex by the ventrolateral part of the midbrain periaqueductal grey matter in rats
-
Inui, K., Murase, S. & Nosaka, S. (1994) Facilitation of the arterial baroreflex by the ventrolateral part of the midbrain periaqueductal grey matter in rats. J. Physiol., 477(Pt 1), 89-101.
-
(1994)
J. Physiol.
, vol.477
, Issue.PT 1
, pp. 89-101
-
-
Inui, K.1
Murase, S.2
Nosaka, S.3
-
103
-
-
0035142746
-
In vitro and in vivo pharmacological characterization of JTE-907, a novel selective ligand for cannabinoid CB2 receptor
-
Iwamura, H., Suzuki, H., Ueda, Y., Kaya, T. & Inaba, T. (2001) In vitro and in vivo pharmacological characterization of JTE-907, a novel selective ligand for cannabinoid CB2 receptor. J. Pharmacol. Exp. Ther., 296, 420-425.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 420-425
-
-
Iwamura, H.1
Suzuki, H.2
Ueda, Y.3
Kaya, T.4
Inaba, T.5
-
104
-
-
0034070409
-
Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter
-
Jarrahian, A., Manna, S., Edgemond, W.S., Campbell, W.B. & Hillard, C.J. (2000) Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter. J. Neurochem., 74, 2597-2606.
-
(2000)
J. Neurochem.
, vol.74
, pp. 2597-2606
-
-
Jarrahian, A.1
Manna, S.2
Edgemond, W.S.3
Campbell, W.B.4
Hillard, C.J.5
-
105
-
-
79951518976
-
Discovery of PF-04457845: a highly potent, orally bioavailable, and selective urea FAAH inhibitor
-
Johnson, D.S., Stiff, C., Lazerwith, S.E., Kesten, S.R., Fay, L.K., Morris, M., Beidler, D., Liimatta, M.B., Smith, S.E., Dudley, D.T., Sadagopan, N., Bhattachar, S.N., Kesten, S.J., Nomanbhoy, T.K., Cravatt, B.F. & Ahn, K. (2011) Discovery of PF-04457845: a highly potent, orally bioavailable, and selective urea FAAH inhibitor. ACS Med. Chem. Lett., 2, 91-96.
-
(2011)
ACS Med. Chem. Lett.
, vol.2
, pp. 91-96
-
-
Johnson, D.S.1
Stiff, C.2
Lazerwith, S.E.3
Kesten, S.R.4
Fay, L.K.5
Morris, M.6
Beidler, D.7
Liimatta, M.B.8
Smith, S.E.9
Dudley, D.T.10
Sadagopan, N.11
Bhattachar, S.N.12
Kesten, S.J.13
Nomanbhoy, T.K.14
Cravatt, B.F.15
Ahn, K.16
-
106
-
-
0019973624
-
Neurotensin: topographical distribution of brain sites involved in hypothermia and antinociception
-
Kalivas, P.W., Jennes, L., Nemeroff, C.B. & Prange, A.J. Jr. (1982) Neurotensin: topographical distribution of brain sites involved in hypothermia and antinociception. J. Comp. Neurol., 210, 225-238.
-
(1982)
J. Comp. Neurol.
, vol.210
, pp. 225-238
-
-
Kalivas, P.W.1
Jennes, L.2
Nemeroff, C.B.3
Prange Jr, A.J.4
-
107
-
-
58249113979
-
Endocannabinoid-mediated control of synaptic transmission
-
Kano, M., Ohno-Shosaku, T., Hashimotodani, Y., Uchigashima, M. & Watanabe, M. (2009) Endocannabinoid-mediated control of synaptic transmission. Physiol. Rev., 89, 309-380.
-
(2009)
Physiol. Rev.
, vol.89
, pp. 309-380
-
-
Kano, M.1
Ohno-Shosaku, T.2
Hashimotodani, Y.3
Uchigashima, M.4
Watanabe, M.5
-
108
-
-
0037234363
-
Modulation of anxiety through blockade of anandamide hydrolysis
-
Kathuria, S., Gaetani, S., Fegley, D., Valino, F., Duranti, A., Tontini, A., Mor, M., Tarzia, G., La Rana, G., Calignano, A., Giustino, A., Tattoli, M., Palmery, M., Cuomo, V. & Piomelli, D. (2003) Modulation of anxiety through blockade of anandamide hydrolysis. Nat. Med., 9, 76-81.
-
(2003)
Nat. Med.
, vol.9
, pp. 76-81
-
-
Kathuria, S.1
Gaetani, S.2
Fegley, D.3
Valino, F.4
Duranti, A.5
Tontini, A.6
Mor, M.7
Tarzia, G.8
La Rana, G.9
Calignano, A.10
Giustino, A.11
Tattoli, M.12
Palmery, M.13
Cuomo, V.14
Piomelli, D.15
-
109
-
-
0345621691
-
Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons
-
Katona, I., Sperlagh, B., Sik, A., Kafalvi, A., Vizi, E.S., Mackie, K. & Freund, T.F. (1999) Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons. J. Neurosci., 19, 4544-4558.
-
(1999)
J. Neurosci.
, vol.19
, pp. 4544-4558
-
-
Katona, I.1
Sperlagh, B.2
Sik, A.3
Kafalvi, A.4
Vizi, E.S.5
Mackie, K.6
Freund, T.F.7
-
110
-
-
79959705331
-
Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey
-
Kawahara, H., Drew, G.M., Christie, M.J. & Vaughan, C.W. (2011) Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. Brit. J. Pharmacol., 163, 1214-1222.
-
(2011)
Brit. J. Pharmacol.
, vol.163
, pp. 1214-1222
-
-
Kawahara, H.1
Drew, G.M.2
Christie, M.J.3
Vaughan, C.W.4
-
111
-
-
79957687799
-
Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain
-
Khasabova, I.A., Chandiramani, A., Harding-Rose, C., Simone, D.A. & Seybold, V.S. (2011) Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. Pharmacol. Res., 64, 60-67.
-
(2011)
Pharmacol. Res.
, vol.64
, pp. 60-67
-
-
Khasabova, I.A.1
Chandiramani, A.2
Harding-Rose, C.3
Simone, D.A.4
Seybold, V.S.5
-
112
-
-
70349110145
-
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain
-
Kinsey, S.G., Long, J.Z., O'Neal, S.T., Abdullah, R.A., Poklis, J.L., Boger, D.L., Cravatt, B.F. & Lichtman, A.H. (2009) Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. J. Pharmacol. Exp. Ther., 330, 902-910.
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.330
, pp. 902-910
-
-
Kinsey, S.G.1
Long, J.Z.2
O'Neal, S.T.3
Abdullah, R.A.4
Poklis, J.L.5
Boger, D.L.6
Cravatt, B.F.7
Lichtman, A.H.8
-
113
-
-
78649685454
-
Fatty acid amide hydrolase and monoacylglycerol lipase inhibitors produce anti-allodynic effects in mice through distinct cannabinoid receptor mechanisms
-
Kinsey, S.G., Long, J.Z., Cravatt, B.F. & Lichtman, A.H. (2010) Fatty acid amide hydrolase and monoacylglycerol lipase inhibitors produce anti-allodynic effects in mice through distinct cannabinoid receptor mechanisms. J. Pain, 11, 1420-1428.
-
(2010)
J. Pain
, vol.11
, pp. 1420-1428
-
-
Kinsey, S.G.1
Long, J.Z.2
Cravatt, B.F.3
Lichtman, A.H.4
-
114
-
-
84878069411
-
Repeated low-dose administration of the monoacylglycerol lipase inhibitor JZL184 retains cannabinoid receptor type 1-mediated antinociceptive and gastroprotective effects
-
Kinsey, S.G., Wise, L.E., Ramesh, D., Abdullah, R., Selley, D.E., Cravatt, B.F. & Lichtman, A.H. (2013) Repeated low-dose administration of the monoacylglycerol lipase inhibitor JZL184 retains cannabinoid receptor type 1-mediated antinociceptive and gastroprotective effects. J. Pharmacol. Exp. Ther., 345, 492-501.
-
(2013)
J. Pharmacol. Exp. Ther.
, vol.345
, pp. 492-501
-
-
Kinsey, S.G.1
Wise, L.E.2
Ramesh, D.3
Abdullah, R.4
Selley, D.E.5
Cravatt, B.F.6
Lichtman, A.H.7
-
115
-
-
0030853692
-
SR141716A is an inverse agonist at the human cannabinoid CB1 receptor
-
Landsman, R.S., Burkey, T.H., Consroe, P., Roeske, W.R. & Yamamura, H.I. (1997) SR141716A is an inverse agonist at the human cannabinoid CB1 receptor. Eur. J. Pharmacol., 334, R1-R2.
-
(1997)
Eur. J. Pharmacol.
, vol.334
-
-
Landsman, R.S.1
Burkey, T.H.2
Consroe, P.3
Roeske, W.R.4
Yamamura, H.I.5
-
116
-
-
54349116152
-
Muscarinic modulation of synaptic transmission via endocannabinoid signalling in the rat midbrain periaqueductal gray
-
Lau, B.K. & Vaughan, C.W. (2008) Muscarinic modulation of synaptic transmission via endocannabinoid signalling in the rat midbrain periaqueductal gray. Mol. Pharmacol., 74, 1392-1398.
-
(2008)
Mol. Pharmacol.
, vol.74
, pp. 1392-1398
-
-
Lau, B.K.1
Vaughan, C.W.2
-
117
-
-
30044435435
-
The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins
-
Lauckner, J.E., Hille, B. & Mackie, K. (2005) The cannabinoid agonist WIN55, 212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins. Proc. Natl. Acad. Sci. USA, 102, 19144-19149.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 19144-19149
-
-
Lauckner, J.E.1
Hille, B.2
Mackie, K.3
-
118
-
-
0008390266
-
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity
-
de Lecea, L., Kilduff, T.S., Peyron, C., Gao, X., Foye, P.E., Danielson, P.E., Fukuhara, C., Battenberg, E.L., Gautvik, V.T., Bartlett, F.S. II., Frankel, W.N., van den Pol, A.N., Bloom, F.E., Gautvik, K.M. & Sutcliffe, J.G. (1998) The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc. Natl. Acad. Sci. USA, 95, 322-327.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 322-327
-
-
de Lecea, L.1
Kilduff, T.S.2
Peyron, C.3
Gao, X.4
Foye, P.E.5
Danielson, P.E.6
Fukuhara, C.7
Battenberg, E.L.8
Gautvik, V.T.9
Bartlett II, F.S.10
Frankel, W.N.11
van den Pol, A.N.12
Bloom, F.E.13
Gautvik, K.M.14
Sutcliffe, J.G.15
-
119
-
-
0033555839
-
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
-
Ledent, C., Valverde, O., Cossu, G., Petitet, F., Aubert, J.F., Beslot, F., Bohme, G.A., Imperato, A., Pedrazzini, T., Roques, B.P., Vassart, G., Fratta, W. & Parmentier, M. (1999) Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science, 283, 401-404.
-
(1999)
Science
, vol.283
, pp. 401-404
-
-
Ledent, C.1
Valverde, O.2
Cossu, G.3
Petitet, F.4
Aubert, J.F.5
Beslot, F.6
Bohme, G.A.7
Imperato, A.8
Pedrazzini, T.9
Roques, B.P.10
Vassart, G.11
Fratta, W.12
Parmentier, M.13
-
120
-
-
33645935391
-
Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids
-
Leung, D., Saghatelian, A., Simon, G.M. & Cravatt, B.F. (2006) Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids. Biochemistry, 45, 4720-4726.
-
(2006)
Biochemistry
, vol.45
, pp. 4720-4726
-
-
Leung, D.1
Saghatelian, A.2
Simon, G.M.3
Cravatt, B.F.4
-
121
-
-
0017361449
-
Evaluation of the periaqueductal central gray (PAG) as a morphine-specific locus of action and examination of morphine-induced and stimulation-produced analgesia at coincident PAG loci
-
Lewis, V.A. & Gebhart, G.F. (1977) Evaluation of the periaqueductal central gray (PAG) as a morphine-specific locus of action and examination of morphine-induced and stimulation-produced analgesia at coincident PAG loci. Brain Res., 124, 283-303.
-
(1977)
Brain Res.
, vol.124
, pp. 283-303
-
-
Lewis, V.A.1
Gebhart, G.F.2
-
122
-
-
79954511348
-
Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibition
-
Liao, H.T., Lee, H.J., Ho, Y.C. & Chiou, L.C. (2011) Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibition. Brit. J. Pharmacol., 163, 330-345.
-
(2011)
Brit. J. Pharmacol.
, vol.163
, pp. 330-345
-
-
Liao, H.T.1
Lee, H.J.2
Ho, Y.C.3
Chiou, L.C.4
-
123
-
-
0030087731
-
Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement
-
Lichtman, A.H., Cook, S.A. & Martin, B.R. (1996) Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement. J. Pharmacol. Exp. Ther., 276, 585-593.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.276
, pp. 585-593
-
-
Lichtman, A.H.1
Cook, S.A.2
Martin, B.R.3
-
124
-
-
0036089489
-
Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo
-
Lichtman, A.H., Hawkins, E.G., Griffin, G. & Cravatt, B.F. (2002) Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo. J. Pharmacol. Exp. Ther., 302, 73-79.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.302
, pp. 73-79
-
-
Lichtman, A.H.1
Hawkins, E.G.2
Griffin, G.3
Cravatt, B.F.4
-
125
-
-
4644354869
-
Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity
-
Lichtman, A.H., Leung, D., Shelton, C.C., Saghatelian, A., Hardouin, C., Boger, D.L. & Cravatt, B.F. (2004a) Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity. J. Pharmacol. Exp. Ther., 311, 441-448.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.311
, pp. 441-448
-
-
Lichtman, A.H.1
Leung, D.2
Shelton, C.C.3
Saghatelian, A.4
Hardouin, C.5
Boger, D.L.6
Cravatt, B.F.7
-
126
-
-
2442510225
-
Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia
-
Lichtman, A.H., Shelton, C.C., Advani, T. & Cravatt, B.F. (2004b) Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. Pain, 109, 319-327.
-
(2004)
Pain
, vol.109
, pp. 319-327
-
-
Lichtman, A.H.1
Shelton, C.C.2
Advani, T.3
Cravatt, B.F.4
-
127
-
-
37349020974
-
Multiple pathways involved in the biosynthesis of anandamide
-
Liu, J., Wang, L., Harvey-White, J., Huang, B.X., Kim, H.Y., Luquet, S., Palmiter, R.D., Krystal, G., Rai, R., Mahadevan, A., Razdan, R.K. & Kunos, G. (2008) Multiple pathways involved in the biosynthesis of anandamide. Neuropharmacology, 54, 1-7.
-
(2008)
Neuropharmacology
, vol.54
, pp. 1-7
-
-
Liu, J.1
Wang, L.2
Harvey-White, J.3
Huang, B.X.4
Kim, H.Y.5
Luquet, S.6
Palmiter, R.D.7
Krystal, G.8
Rai, R.9
Mahadevan, A.10
Razdan, R.K.11
Kunos, G.12
-
128
-
-
67651100845
-
Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism
-
Long, J.Z., Nomura, D.K. & Cravatt, B.F. (2009a) Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism. Chem. Biol., 16, 744-753.
-
(2009)
Chem. Biol.
, vol.16
, pp. 744-753
-
-
Long, J.Z.1
Nomura, D.K.2
Cravatt, B.F.3
-
129
-
-
73949109254
-
Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo
-
Long, J.Z., Nomura, D.K., Vann, R.E., Walentiny, D.M., Booker, L., Jin, X., Burston, J.J., Sim-Selley, L.J., Lichtman, A.H., Wiley, J.L. & Cravatt, B.F. (2009b) Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. Proc. Natl. Acad. Sci. USA, 106, 20270-20275.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 20270-20275
-
-
Long, J.Z.1
Nomura, D.K.2
Vann, R.E.3
Walentiny, D.M.4
Booker, L.5
Jin, X.6
Burston, J.J.7
Sim-Selley, L.J.8
Lichtman, A.H.9
Wiley, J.L.10
Cravatt, B.F.11
-
130
-
-
79955918810
-
Pharmacogenetics of new analgesics
-
Lotsch, J. & Geisslinger, G. (2011) Pharmacogenetics of new analgesics. Brit. J. Pharmacol., 163, 447-460.
-
(2011)
Brit. J. Pharmacol.
, vol.163
, pp. 447-460
-
-
Lotsch, J.1
Geisslinger, G.2
-
131
-
-
0028823316
-
Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor
-
Mackie, K., Lai, Y., Westenbroek, R. & Mitchell, R. (1995) Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor. J. Neurosci., 15, 6552-6561.
-
(1995)
J. Neurosci.
, vol.15
, pp. 6552-6561
-
-
Mackie, K.1
Lai, Y.2
Westenbroek, R.3
Mitchell, R.4
-
132
-
-
0032401793
-
Characterisation of mGluRs which modulate nociception in the PAG of the mouse
-
Maione, S., Marabese, I., Leyva, J., Palazzo, E., de Novellis, V. & Rossi, F. (1998) Characterisation of mGluRs which modulate nociception in the PAG of the mouse. Neuropharmacology, 37, 1475-1483.
-
(1998)
Neuropharmacology
, vol.37
, pp. 1475-1483
-
-
Maione, S.1
Marabese, I.2
Leyva, J.3
Palazzo, E.4
de Novellis, V.5
Rossi, F.6
-
133
-
-
0033975262
-
Periaqueductal gray matter metabotropic glutamate receptors modulate formalin-induced nociception
-
Maione, S., Oliva, P., Marabese, I., Palazzo, E., Rossi, F., Berrino, L. & Filippelli, A. (2000) Periaqueductal gray matter metabotropic glutamate receptors modulate formalin-induced nociception. Pain, 85, 183-189.
-
(2000)
Pain
, vol.85
, pp. 183-189
-
-
Maione, S.1
Oliva, P.2
Marabese, I.3
Palazzo, E.4
Rossi, F.5
Berrino, L.6
Filippelli, A.7
-
134
-
-
33644766044
-
Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors
-
Maione, S., Bisogno, T., de Novellis, V., Palazzo, E., Cristino, L., Valenti, M., Petrosino, S., Guglielmotti, V., Rossi, F. & Di Marzo, V. (2006) Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors. J. Pharmacol. Exp. Ther., 316, 969-982.
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.316
, pp. 969-982
-
-
Maione, S.1
Bisogno, T.2
de Novellis, V.3
Palazzo, E.4
Cristino, L.5
Valenti, M.6
Petrosino, S.7
Guglielmotti, V.8
Rossi, F.9
Di Marzo, V.10
-
135
-
-
0034886018
-
CB2 cannabinoid receptor-mediated peripheral antinociception
-
Malan, T.P. Jr., Ibrahim, M.M., Deng, H., Liu, Q., Mata, H.P., Vanderah, T., Porreca, F. & Makriyannis, A. (2001) CB2 cannabinoid receptor-mediated peripheral antinociception. Pain, 93, 239-245.
-
(2001)
Pain
, vol.93
, pp. 239-245
-
-
Malan Jr, T.P.1
Ibrahim, M.M.2
Deng, H.3
Liu, Q.4
Mata, H.P.5
Vanderah, T.6
Porreca, F.7
Makriyannis, A.8
-
136
-
-
34447573681
-
Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception
-
Marabese, I., Rossi, F., Palazzo, E., de Novellis, V., Starowicz, K., Cristino, L., Vita, D., Gatta, L., Guida, F., Di Marzo, V., Rossi, F. & Maione, S. (2007) Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception. J. Neurophysiol., 98, 43-53.
-
(2007)
J. Neurophysiol.
, vol.98
, pp. 43-53
-
-
Marabese, I.1
Rossi, F.2
Palazzo, E.3
de Novellis, V.4
Starowicz, K.5
Cristino, L.6
Vita, D.7
Gatta, L.8
Guida, F.9
Di Marzo, V.10
Rossi, F.11
Maione, S.12
-
137
-
-
26844448746
-
Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli
-
Maresz, K., Carrier, E.J., Ponomarev, E.D., Hillard, C.J. & Dittel, B.N. (2005) Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli. J. Neurochem., 95, 437-445.
-
(2005)
J. Neurochem.
, vol.95
, pp. 437-445
-
-
Maresz, K.1
Carrier, E.J.2
Ponomarev, E.D.3
Hillard, C.J.4
Dittel, B.N.5
-
138
-
-
77955053537
-
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
-
Marrs, W.R., Blankman, J.L., Horne, E.A., Thomazeau, A., Lin, Y.H., Coy, J., Bodor, A.L., Muccioli, G.G., Hu, S.S., Woodruff, G., Fung, S., Lafourcade, M., Alexander, J.P., Long, J.Z., Li, W., Xu, C., Moller, T., Mackie, K., Manzoni, O.J., Cravatt, B.F. & Stella, N. (2010) The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nat. Neurosci., 13, 951-957.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 951-957
-
-
Marrs, W.R.1
Blankman, J.L.2
Horne, E.A.3
Thomazeau, A.4
Lin, Y.H.5
Coy, J.6
Bodor, A.L.7
Muccioli, G.G.8
Hu, S.S.9
Woodruff, G.10
Fung, S.11
Lafourcade, M.12
Alexander, J.P.13
Long, J.Z.14
Li, W.15
Xu, C.16
Moller, T.17
Mackie, K.18
Manzoni, O.J.19
Cravatt, B.F.20
Stella, N.21
more..
-
139
-
-
0036682222
-
The endogenous cannabinoid system controls extinction of aversive memories
-
Marsicano, G., Wotjak, C.T., Azad, S.C., Bisogno, T., Rammes, G., Cascio, M.G., Hermann, H., Tang, J., Hofmann, C., Zieglgansberger, W., Di Marzo, V. & Lutz, B. (2002) The endogenous cannabinoid system controls extinction of aversive memories. Nature, 418, 530-534.
-
(2002)
Nature
, vol.418
, pp. 530-534
-
-
Marsicano, G.1
Wotjak, C.T.2
Azad, S.C.3
Bisogno, T.4
Rammes, G.5
Cascio, M.G.6
Hermann, H.7
Tang, J.8
Hofmann, C.9
Zieglgansberger, W.10
Di Marzo, V.11
Lutz, B.12
-
140
-
-
0029036140
-
An examination of the central sites of action of cannabinoid-induced antinociception in the rat
-
Martin, W.J., Patrick, S.L., Coffin, P.O., Tsou, K. & Walker, J.M. (1995) An examination of the central sites of action of cannabinoid-induced antinociception in the rat. Life Sci., 56, 2103-2109.
-
(1995)
Life Sci.
, vol.56
, pp. 2103-2109
-
-
Martin, W.J.1
Patrick, S.L.2
Coffin, P.O.3
Tsou, K.4
Walker, J.M.5
-
141
-
-
0029816889
-
Suppression of noxious stimulus-evoked activity in the ventral posterolateral nucleus of the thalamus by a cannabinoid agonist: correlation between electrophysiological and antinociceptive effects
-
Martin, W.J., Hohmann, A.G. & Walker, J.M. (1996) Suppression of noxious stimulus-evoked activity in the ventral posterolateral nucleus of the thalamus by a cannabinoid agonist: correlation between electrophysiological and antinociceptive effects. J. Neurosci., 16, 6601-6611.
-
(1996)
J. Neurosci.
, vol.16
, pp. 6601-6611
-
-
Martin, W.J.1
Hohmann, A.G.2
Walker, J.M.3
-
142
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda, L.A., Lolait, S.J., Brownstein, M.J., Young, A.C. & Bonner, T.I. (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature, 346, 561-564.
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
143
-
-
37349043211
-
Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area
-
Matyas, F., Urban, G.M., Watanabe, M., Mackie, K., Zimmer, A., Freund, T.F. & Katona, I. (2008) Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area. Neuropharmacology, 54, 95-107.
-
(2008)
Neuropharmacology
, vol.54
, pp. 95-107
-
-
Matyas, F.1
Urban, G.M.2
Watanabe, M.3
Mackie, K.4
Zimmer, A.5
Freund, T.F.6
Katona, I.7
-
144
-
-
0029012014
-
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
-
Mechoulam, R., Ben-Shabat, S., Hanus, L., Ligumsky, M., Kaminski, N.E., Schatz, A.R., Gopher, A., Almog, S., Martin, B.R., Compton, D.R., Pertwee, R.G., Griffin, G., Bayewitch, M., Barg, J. & Vogel, Z. (1995) Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem. Pharmacol., 50, 83-90.
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 83-90
-
-
Mechoulam, R.1
Ben-Shabat, S.2
Hanus, L.3
Ligumsky, M.4
Kaminski, N.E.5
Schatz, A.R.6
Gopher, A.7
Almog, S.8
Martin, B.R.9
Compton, D.R.10
Pertwee, R.G.11
Griffin, G.12
Bayewitch, M.13
Barg, J.14
Vogel, Z.15
-
145
-
-
0032563792
-
An analgesia circuit activated by cannabinoids
-
Meng, I.D., Manning, B.H., Martin, W.J. & Fields, H.L. (1998) An analgesia circuit activated by cannabinoids. Nature, 395, 381-383.
-
(1998)
Nature
, vol.395
, pp. 381-383
-
-
Meng, I.D.1
Manning, B.H.2
Martin, W.J.3
Fields, H.L.4
-
146
-
-
0036277865
-
Descending control of pain
-
Millan, M.J. (2002) Descending control of pain. Prog. Neurobiol., 66, 355-474.
-
(2002)
Prog. Neurobiol.
, vol.66
, pp. 355-474
-
-
Millan, M.J.1
-
147
-
-
66549112067
-
Neurotensin inhibition of GABAergic transmission via mGluR-induced endocannabinoid signalling in rat periaqueductal grey
-
Mitchell, V.A., Kawahara, H. & Vaughan, C.W. (2009) Neurotensin inhibition of GABAergic transmission via mGluR-induced endocannabinoid signalling in rat periaqueductal grey. J. Physiol., 587, 2511-2520.
-
(2009)
J. Physiol.
, vol.587
, pp. 2511-2520
-
-
Mitchell, V.A.1
Kawahara, H.2
Vaughan, C.W.3
-
148
-
-
79960329361
-
Cholecystokinin exerts an effect via the endocannabinoid system to inhibit GABAergic transmission in midbrain periaqueductal gray
-
Mitchell, V.A., Jeong, H.J., Drew, G.M. & Vaughan, C.W. (2011) Cholecystokinin exerts an effect via the endocannabinoid system to inhibit GABAergic transmission in midbrain periaqueductal gray. Neuropsychopharmacol., 36, 1801-1810.
-
(2011)
Neuropsychopharmacol.
, vol.36
, pp. 1801-1810
-
-
Mitchell, V.A.1
Jeong, H.J.2
Drew, G.M.3
Vaughan, C.W.4
-
149
-
-
0030785650
-
Involvement of the cholinergic system and periaqueductal gray matter in the modulation of tonic immobility in the guinea pig
-
Monassi, C.R., Hoffmann, A. & Menescal-de-Oliveira, L. (1997) Involvement of the cholinergic system and periaqueductal gray matter in the modulation of tonic immobility in the guinea pig. Physiol. Behav., 62, 53-59.
-
(1997)
Physiol. Behav.
, vol.62
, pp. 53-59
-
-
Monassi, C.R.1
Hoffmann, A.2
Menescal-de-Oliveira, L.3
-
150
-
-
0032584966
-
Immobility and flight associated with antinociception produced by activation of the ventral and lateral/dorsal regions of the rat periaqueductal gray
-
Morgan, M.M., Whitney, P.K. & Gold, M.S. (1998) Immobility and flight associated with antinociception produced by activation of the ventral and lateral/dorsal regions of the rat periaqueductal gray. Brain Res., 804, 159-166.
-
(1998)
Brain Res.
, vol.804
, pp. 159-166
-
-
Morgan, M.M.1
Whitney, P.K.2
Gold, M.S.3
-
151
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro, S., Thomas, K.L. & Abu-Shaar, M. (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature, 365, 61-65.
-
(1993)
Nature
, vol.365
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
152
-
-
0038521050
-
Selective activation of cannabinoid CB(2) receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation
-
Nackley, A.G., Makriyannis, A. & Hohmann, A.G. (2003a) Selective activation of cannabinoid CB(2) receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation. Neuroscience, 119, 747-757.
-
(2003)
Neuroscience
, vol.119
, pp. 747-757
-
-
Nackley, A.G.1
Makriyannis, A.2
Hohmann, A.G.3
-
153
-
-
0037475146
-
A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation
-
Nackley, A.G., Suplita, R.L. II. & Hohmann, A.G. (2003b) A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation. Neuroscience, 117, 659-670.
-
(2003)
Neuroscience
, vol.117
, pp. 659-670
-
-
Nackley, A.G.1
Suplita II, R.L.2
Hohmann, A.G.3
-
154
-
-
0037458721
-
Group I metabotropic glutamate receptors modulate glutamate and gamma-aminobutyric acid release in the periaqueductal grey of rats
-
de Novellis, V., Marabese, I., Palazzo, E., Rossi, F., Berrino, L., Rodella, L., Bianchi, R. & Maione, S. (2003) Group I metabotropic glutamate receptors modulate glutamate and gamma-aminobutyric acid release in the periaqueductal grey of rats. Eur. J. Pharmacol., 462, 73-81.
-
(2003)
Eur. J. Pharmacol.
, vol.462
, pp. 73-81
-
-
de Novellis, V.1
Marabese, I.2
Palazzo, E.3
Rossi, F.4
Berrino, L.5
Rodella, L.6
Bianchi, R.7
Maione, S.8
-
155
-
-
0027937531
-
Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization
-
Nusser, Z., Mulvihill, E., Streit, P. & Somogyi, P. (1994) Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization. Neuroscience, 61, 421-427.
-
(1994)
Neuroscience
, vol.61
, pp. 421-427
-
-
Nusser, Z.1
Mulvihill, E.2
Streit, P.3
Somogyi, P.4
-
156
-
-
38749090554
-
Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals
-
Nyilas, R., Dudok, B., Urban, G.M., Mackie, K., Watanabe, M., Cravatt, B.F., Freund, T.F. & Katona, I. (2008) Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals. J. Neurosci., 28, 1058-1063.
-
(2008)
J. Neurosci.
, vol.28
, pp. 1058-1063
-
-
Nyilas, R.1
Dudok, B.2
Urban, G.M.3
Mackie, K.4
Watanabe, M.5
Cravatt, B.F.6
Freund, T.F.7
Katona, I.8
-
157
-
-
65749102603
-
Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia
-
Nyilas, R., Gregg, L.C., Mackie, K., Watanabe, M., Zimmer, A., Hohmann, A.G. & Katona, I. (2009) Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia. Eur. J. Neurosci., 29, 1964-1978.
-
(2009)
Eur. J. Neurosci.
, vol.29
, pp. 1964-1978
-
-
Nyilas, R.1
Gregg, L.C.2
Mackie, K.3
Watanabe, M.4
Zimmer, A.5
Hohmann, A.G.6
Katona, I.7
-
158
-
-
0029120580
-
Distributions of the mRNAs for L-2-amino-4-phosphonobutyrate-sensitive metabotropic glutamate receptors, mGluR4 and mGluR7, in the rat brain
-
Ohishi, H., Akazawa, C., Shigemoto, R., Nakanishi, S. & Mizuno, N. (1995) Distributions of the mRNAs for L-2-amino-4-phosphonobutyrate-sensitive metabotropic glutamate receptors, mGluR4 and mGluR7, in the rat brain. J. Comp. Neurol., 360, 555-570.
-
(1995)
J. Comp. Neurol.
, vol.360
, pp. 555-570
-
-
Ohishi, H.1
Akazawa, C.2
Shigemoto, R.3
Nakanishi, S.4
Mizuno, N.5
-
159
-
-
34548512479
-
Biosynthetic pathways of the endocannabinoid anandamide
-
Okamoto, Y., Wang, J., Morishita, J. & Ueda, N. (2007) Biosynthetic pathways of the endocannabinoid anandamide. Chem. Biodivers., 4, 1842-1857.
-
(2007)
Chem. Biodivers.
, vol.4
, pp. 1842-1857
-
-
Okamoto, Y.1
Wang, J.2
Morishita, J.3
Ueda, N.4
-
160
-
-
80054988724
-
The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nociceptive tone
-
Olango, W.M., Roche, M., Ford, G.K., Harhen, B. & Finn, D.P. (2012) The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nociceptive tone. Brit. J. Pharmacol., 165, 2549-2560.
-
(2012)
Brit. J. Pharmacol.
, vol.165
, pp. 2549-2560
-
-
Olango, W.M.1
Roche, M.2
Ford, G.K.3
Harhen, B.4
Finn, D.P.5
-
161
-
-
29844444786
-
Role of periaqueductal grey prostaglandin receptors in formalin-induced hyperalgesia
-
Oliva, P., Berrino, L., de Novellis, V., Palazzo, E., Marabese, I., Siniscalco, D., Scafuro, M., Mariani, L., Rossi, F. & Maione, S. (2006) Role of periaqueductal grey prostaglandin receptors in formalin-induced hyperalgesia. Eur. J. Pharmacol., 530, 40-47.
-
(2006)
Eur. J. Pharmacol.
, vol.530
, pp. 40-47
-
-
Oliva, P.1
Berrino, L.2
de Novellis, V.3
Palazzo, E.4
Marabese, I.5
Siniscalco, D.6
Scafuro, M.7
Mariani, L.8
Rossi, F.9
Maione, S.10
-
162
-
-
0035134263
-
Metabotropic and NMDA glutamate receptors participate in the cannabinoid-induced antinociception
-
Palazzo, E., Marabese, I., de Novellis, V., Oliva, P., Rossi, F., Berrino, L. & Maione, S. (2001) Metabotropic and NMDA glutamate receptors participate in the cannabinoid-induced antinociception. Neuropharmacology, 40, 319-326.
-
(2001)
Neuropharmacology
, vol.40
, pp. 319-326
-
-
Palazzo, E.1
Marabese, I.2
de Novellis, V.3
Oliva, P.4
Rossi, F.5
Berrino, L.6
Maione, S.7
-
163
-
-
0037192598
-
Interaction between vanilloid and glutamate receptors in the central modulation of nociception
-
Palazzo, E., de Novellis, V., Marabese, I., Cuomo, D., Rossi, F., Berrino, L. & Maione, S. (2002) Interaction between vanilloid and glutamate receptors in the central modulation of nociception. Eur. J. Pharmacol., 439, 69-75.
-
(2002)
Eur. J. Pharmacol.
, vol.439
, pp. 69-75
-
-
Palazzo, E.1
de Novellis, V.2
Marabese, I.3
Cuomo, D.4
Rossi, F.5
Berrino, L.6
Maione, S.7
-
164
-
-
80054821338
-
EP1 receptor within the ventrolateral periaqueductal grey controls thermonociception and rostral ventromedial medulla cell activity in healthy and neuropathic rat
-
Palazzo, E., Guida, F., Gatta, L., Luongo, L., Boccella, S., Bellini, G., Marabese, I., de Novellis, V., Rossi, F. & Maione, S. (2011) EP1 receptor within the ventrolateral periaqueductal grey controls thermonociception and rostral ventromedial medulla cell activity in healthy and neuropathic rat. Mol. Pain, 7, 82.
-
(2011)
Mol. Pain
, vol.7
, pp. 82
-
-
Palazzo, E.1
Guida, F.2
Gatta, L.3
Luongo, L.4
Boccella, S.5
Bellini, G.6
Marabese, I.7
de Novellis, V.8
Rossi, F.9
Maione, S.10
-
165
-
-
84871380135
-
Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor
-
Pamplona, F.A., Ferreira, J., Menezes de Lima, O. Jr., Duarte, F.S., Bento, A.F., Forner, S., Villarinho, J.G., Bellocchio, L., Wotjak, C.T., Lerner, R., Monory, K., Lutz, B., Canetti, C., Matias, I., Calixto, J.B., Marsicano, G., Guimaraes, M.Z. & Takahashi, R.N. (2012) Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor. Proc. Natl. Acad. Sci. USA, 109, 21134-21139.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 21134-21139
-
-
Pamplona, F.A.1
Ferreira, J.2
Menezes de Lima Jr, O.3
Duarte, F.S.4
Bento, A.F.5
Forner, S.6
Villarinho, J.G.7
Bellocchio, L.8
Wotjak, C.T.9
Lerner, R.10
Monory, K.11
Lutz, B.12
Canetti, C.13
Matias, I.14
Calixto, J.B.15
Marsicano, G.16
Guimaraes, M.Z.17
Takahashi, R.N.18
-
166
-
-
0033452453
-
Neuropeptide FF and modulation of pain
-
Panula, P., Kalso, E., Nieminen, M., Kontinen, V.K., Brandt, A. & Pertovaara, A. (1999) Neuropeptide FF and modulation of pain. Brain Res., 848, 191-196.
-
(1999)
Brain Res.
, vol.848
, pp. 191-196
-
-
Panula, P.1
Kalso, E.2
Nieminen, M.3
Kontinen, V.K.4
Brandt, A.5
Pertovaara, A.6
-
167
-
-
84894559946
-
FAAH selectively influences placebo effects
-
doi:10.1038/mp.2013.124. [Epub ahead of print].
-
Pecina, M., Martinez-Jauand, M., Hodgkinson, C., Stohler, C.S., Goldman, D. & Zubieta, J.K. (2013) FAAH selectively influences placebo effects. Mol. Psychiatr., doi:10.1038/mp.2013.124. [Epub ahead of print].
-
(2013)
Mol. Psychiatr.
-
-
Pecina, M.1
Martinez-Jauand, M.2
Hodgkinson, C.3
Stohler, C.S.4
Goldman, D.5
Zubieta, J.K.6
-
168
-
-
77956691506
-
Effects of central neuropeptide S in the mouse formalin test
-
Peng, Y.L., Zhang, J.N., Chang, M., Li, W., Han, R.W. & Wang, R. (2010) Effects of central neuropeptide S in the mouse formalin test. Peptides, 31, 1878-1883.
-
(2010)
Peptides
, vol.31
, pp. 1878-1883
-
-
Peng, Y.L.1
Zhang, J.N.2
Chang, M.3
Li, W.4
Han, R.W.5
Wang, R.6
-
169
-
-
68449087610
-
Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain sensitization
-
Pernia-Andrade, A.J., Kato, A., Witschi, R., Nyilas, R., Katona, I., Freund, T.F., Watanabe, M., Filitz, J., Koppert, W., Schuttler, J., Ji, G., Neugebauer, V., Marsicano, G., Lutz, B., Vanegas, H. & Zeilhofer, H.U. (2009) Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain sensitization. Science, 325, 760-764.
-
(2009)
Science
, vol.325
, pp. 760-764
-
-
Pernia-Andrade, A.J.1
Kato, A.2
Witschi, R.3
Nyilas, R.4
Katona, I.5
Freund, T.F.6
Watanabe, M.7
Filitz, J.8
Koppert, W.9
Schuttler, J.10
Ji, G.11
Neugebauer, V.12
Marsicano, G.13
Lutz, B.14
Vanegas, H.15
Zeilhofer, H.U.16
-
170
-
-
0018822714
-
Bombesin: receptor distribution in brain and effects on nociception and locomotor activity
-
Pert, A., Moody, T.W., Pert, C.B., Dewald, L.A. & Rivier, J. (1980) Bombesin: receptor distribution in brain and effects on nociception and locomotor activity. Brain Res., 193, 209-220.
-
(1980)
Brain Res.
, vol.193
, pp. 209-220
-
-
Pert, A.1
Moody, T.W.2
Pert, C.B.3
Dewald, L.A.4
Rivier, J.5
-
171
-
-
12744258029
-
Inverse agonism and neutral antagonism at cannabinoid CB1 receptors
-
Pertwee, R.G. (2005) Inverse agonism and neutral antagonism at cannabinoid CB1 receptors. Life Sci., 76, 1307-1324.
-
(2005)
Life Sci.
, vol.76
, pp. 1307-1324
-
-
Pertwee, R.G.1
-
172
-
-
38349158960
-
The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin
-
Pertwee, R.G. (2008a) The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. Brit. J. Pharmacol., 153, 199-215.
-
(2008)
Brit. J. Pharmacol.
, vol.153
, pp. 199-215
-
-
Pertwee, R.G.1
-
173
-
-
43949121784
-
Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond
-
Pertwee, R.G. (2008b) Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond. Addict. Biol., 13, 147-159.
-
(2008)
Addict. Biol.
, vol.13
, pp. 147-159
-
-
Pertwee, R.G.1
-
174
-
-
84871389314
-
Lipoxin A4 is an allosteric endocannabinoid that strengthens anandamide-induced CB1 receptor activation
-
Pertwee, R.G. (2012) Lipoxin A4 is an allosteric endocannabinoid that strengthens anandamide-induced CB1 receptor activation. Proc. Natl. Acad. Sci. USA, 109, 20781-20782.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 20781-20782
-
-
Pertwee, R.G.1
-
175
-
-
84893150605
-
Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applications
-
Pertwee, R.G. (2013) Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applications. Proc. Nutr. Soc., 18, 1-10.
-
(2013)
Proc. Nutr. Soc.
, vol.18
, pp. 1-10
-
-
Pertwee, R.G.1
-
176
-
-
78650120798
-
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB(1) and CB(2)
-
Pertwee, R.G., Howlett, A.C., Abood, M.E., Alexander, S.P., Di Marzo, V., Elphick, M.R., Greasley, P.J., Hansen, H.S., Kunos, G., Mackie, K., Mechoulam, R. & Ross, R.A. (2010) International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB(1) and CB(2). Pharmacol. Rev., 62, 588-631.
-
(2010)
Pharmacol. Rev.
, vol.62
, pp. 588-631
-
-
Pertwee, R.G.1
Howlett, A.C.2
Abood, M.E.3
Alexander, S.P.4
Di Marzo, V.5
Elphick, M.R.6
Greasley, P.J.7
Hansen, H.S.8
Kunos, G.9
Mackie, K.10
Mechoulam, R.11
Ross, R.A.12
-
177
-
-
0032402181
-
Neurons containing hypocretin (orexin) project to multiple neuronal systems
-
Peyron, C., Tighe, D.K., van den Pol, A.N., de Lecea, L., Heller, H.C., Sutcliffe, J.G. & Kilduff, T.S. (1998) Neurons containing hypocretin (orexin) project to multiple neuronal systems. J. Neurosci., 18, 9996-10015.
-
(1998)
J. Neurosci.
, vol.18
, pp. 9996-10015
-
-
Peyron, C.1
Tighe, D.K.2
van den Pol, A.N.3
de Lecea, L.4
Heller, H.C.5
Sutcliffe, J.G.6
Kilduff, T.S.7
-
178
-
-
0028912822
-
The metabotropic glutamate receptors: structure and functions
-
Pin, J.P. & Duvoisin, R. (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology, 34, 1-26.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1-26
-
-
Pin, J.P.1
Duvoisin, R.2
-
179
-
-
0034212295
-
The endocannabinoid system as a target for therapeutic drugs
-
Piomelli, D., Giuffrida, A., Calignano, A. & Rodriguez de Fonseca, F. (2000) The endocannabinoid system as a target for therapeutic drugs. Trends Pharmacol. Sci., 21, 218-224.
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, pp. 218-224
-
-
Piomelli, D.1
Giuffrida, A.2
Calignano, A.3
Rodriguez de Fonseca, F.4
-
180
-
-
0033561178
-
Hypothalamic hypocretin (orexin): robust innervation of the spinal cord
-
van den Pol, A.N. (1999) Hypothalamic hypocretin (orexin): robust innervation of the spinal cord. J. Neurosci., 19, 3171-3182.
-
(1999)
J. Neurosci.
, vol.19
, pp. 3171-3182
-
-
van den Pol, A.N.1
-
181
-
-
0036260823
-
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor
-
Porter, A.C., Sauer, J.M., Knierman, M.D., Becker, G.W., Berna, M.J., Bao, J., Nomikos, G.G., Carter, P., Bymaster, F.P., Leese, A.B. & Felder, C.C. (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J. Pharmacol. Exp. Ther., 301, 1020-1024.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.301
, pp. 1020-1024
-
-
Porter, A.C.1
Sauer, J.M.2
Knierman, M.D.3
Becker, G.W.4
Berna, M.J.5
Bao, J.6
Nomikos, G.G.7
Carter, P.8
Bymaster, F.P.9
Leese, A.B.10
Felder, C.C.11
-
182
-
-
84868151583
-
Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids
-
Puighermanal, E., Busquets-Garcia, A., Maldonado, R. & Ozaita, A. (2012) Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids. Philos. T. Roy. Soc. B., 367, 3254-3263.
-
(2012)
Philos. T. Roy. Soc. B.
, vol.367
, pp. 3254-3263
-
-
Puighermanal, E.1
Busquets-Garcia, A.2
Maldonado, R.3
Ozaita, A.4
-
183
-
-
58149343351
-
Interferon-gamma is a critical modulator of CB(2) cannabinoid receptor signaling during neuropathic pain
-
Racz, I., Nadal, X., Alferink, J., Banos, J.E., Rehnelt, J., Martin, M., Pintado, B., Gutierrez-Adan, A., Sanguino, E., Bellora, N., Manzanares, J., Zimmer, A. & Maldonado, R. (2008a) Interferon-gamma is a critical modulator of CB(2) cannabinoid receptor signaling during neuropathic pain. J. Neurosci., 28, 12136-12145.
-
(2008)
J. Neurosci.
, vol.28
, pp. 12136-12145
-
-
Racz, I.1
Nadal, X.2
Alferink, J.3
Banos, J.E.4
Rehnelt, J.5
Martin, M.6
Pintado, B.7
Gutierrez-Adan, A.8
Sanguino, E.9
Bellora, N.10
Manzanares, J.11
Zimmer, A.12
Maldonado, R.13
-
184
-
-
58149339634
-
Crucial role of CB(2) cannabinoid receptor in the regulation of central immune responses during neuropathic pain
-
Racz, I., Nadal, X., Alferink, J., Banos, J.E., Rehnelt, J., Martin, M., Pintado, B., Gutierrez-Adan, A., Sanguino, E., Manzanares, J., Zimmer, A. & Maldonado, R. (2008b) Crucial role of CB(2) cannabinoid receptor in the regulation of central immune responses during neuropathic pain. J. Neurosci., 28, 12125-12135.
-
(2008)
J. Neurosci.
, vol.28
, pp. 12125-12135
-
-
Racz, I.1
Nadal, X.2
Alferink, J.3
Banos, J.E.4
Rehnelt, J.5
Martin, M.6
Pintado, B.7
Gutierrez-Adan, A.8
Sanguino, E.9
Manzanares, J.10
Zimmer, A.11
Maldonado, R.12
-
185
-
-
0014690325
-
Surgery in the rat during electrical analgesia induced by focal brain stimulation
-
Reynolds, D.V. (1969) Surgery in the rat during electrical analgesia induced by focal brain stimulation. Science, 164, 444-445.
-
(1969)
Science
, vol.164
, pp. 444-445
-
-
Reynolds, D.V.1
-
186
-
-
0031660109
-
Cannabinoid receptor activation differentially regulates the various adenylyl cyclase isozymes
-
Rhee, M.H., Bayewitch, M., Avidor-Reiss, T., Levy, R. & Vogel, Z. (1998) Cannabinoid receptor activation differentially regulates the various adenylyl cyclase isozymes. J. Neurochem., 71, 1525-1534.
-
(1998)
J. Neurochem.
, vol.71
, pp. 1525-1534
-
-
Rhee, M.H.1
Bayewitch, M.2
Avidor-Reiss, T.3
Levy, R.4
Vogel, Z.5
-
187
-
-
0031032872
-
SR 141716A, a cannabinoid receptor antagonist, produces hyperalgesia in untreated mice
-
Richardson, J.D., Aanonsen, L. & Hargreaves, K.M. (1997) SR 141716A, a cannabinoid receptor antagonist, produces hyperalgesia in untreated mice. Eur. J. Pharmacol., 319, R3-R4.
-
(1997)
Eur. J. Pharmacol.
, vol.319
-
-
Richardson, J.D.1
Aanonsen, L.2
Hargreaves, K.M.3
-
188
-
-
0031974179
-
Hypoactivity of the spinal cannabinoid system results in NMDA-dependent hyperalgesia
-
Richardson, J.D., Aanonsen, L. & Hargreaves, K.M. (1998a) Hypoactivity of the spinal cannabinoid system results in NMDA-dependent hyperalgesia. J. Neurosci., 18, 451-457.
-
(1998)
J. Neurosci.
, vol.18
, pp. 451-457
-
-
Richardson, J.D.1
Aanonsen, L.2
Hargreaves, K.M.3
-
189
-
-
0031779305
-
Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors
-
Richardson, J.D., Kilo, S. & Hargreaves, K.M. (1998b) Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. Pain, 75, 111-119.
-
(1998)
Pain
, vol.75
, pp. 111-119
-
-
Richardson, J.D.1
Kilo, S.2
Hargreaves, K.M.3
-
190
-
-
0030005401
-
Function of metabotropic glutamate receptors in learning and memory
-
Riedel, G. (1996) Function of metabotropic glutamate receptors in learning and memory. Trends Neurosci., 19, 219-224.
-
(1996)
Trends Neurosci.
, vol.19
, pp. 219-224
-
-
Riedel, G.1
-
191
-
-
0028129936
-
SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
-
Rinaldi-Carmona, M., Barth, F., Héaulme, M., Shire, D., Calandra, B., Congy, C., Martinez, S., Maruani, J., Néliat, G., Caput, D., Ferrara, P., Soubrié, P., Brelière, J.C. & Le Fur, G. (1994) SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett., 350, 240-244.
-
(1994)
FEBS Lett.
, vol.350
, pp. 240-244
-
-
Rinaldi-Carmona, M.1
Barth, F.2
Héaulme, M.3
Shire, D.4
Calandra, B.5
Congy, C.6
Martinez, S.7
Maruani, J.8
Néliat, G.9
Caput, D.10
Ferrara, P.11
Soubrié, P.12
Brelière, J.C.13
Le Fur, G.14
-
192
-
-
1242269973
-
Substance P microinjected into the periaqueductal gray matter induces antinociception and is released following morphine administration
-
Rosen, A., Zhang, Y.X., Lund, I., Lundeberg, T. & Yu, L.C. (2004) Substance P microinjected into the periaqueductal gray matter induces antinociception and is released following morphine administration. Brain Res., 1001, 87-94.
-
(2004)
Brain Res.
, vol.1001
, pp. 87-94
-
-
Rosen, A.1
Zhang, Y.X.2
Lund, I.3
Lundeberg, T.4
Yu, L.C.5
-
193
-
-
84879135358
-
Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons: distinctive sufficiency for hippocampus-dependent and amygdala-dependent synaptic and behavioral functions
-
Ruehle, S., Remmers, F., Romo-Parra, H., Massa, F., Wickert, M., Wortge, S., Haring, M., Kaiser, N., Marsicano, G., Pape, H.C. & Lutz, B. (2013) Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons: distinctive sufficiency for hippocampus-dependent and amygdala-dependent synaptic and behavioral functions. J. Neurosci., 33, 10264-10277.
-
(2013)
J. Neurosci.
, vol.33
, pp. 10264-10277
-
-
Ruehle, S.1
Remmers, F.2
Romo-Parra, H.3
Massa, F.4
Wickert, M.5
Wortge, S.6
Haring, M.7
Kaiser, N.8
Marsicano, G.9
Pape, H.C.10
Lutz, B.11
-
194
-
-
34250750792
-
The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3′-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice
-
Russo, R., Loverme, J., La Rana, G., Compton, T.R., Parrott, J., Duranti, A., Tontini, A., Mor, M., Tarzia, G., Calignano, A. & Piomelli, D. (2007) The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3′-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice. J. Pharmacol. Exp. Ther., 322, 236-242.
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.322
, pp. 236-242
-
-
Russo, R.1
Loverme, J.2
La Rana, G.3
Compton, T.R.4
Parrott, J.5
Duranti, A.6
Tontini, A.7
Mor, M.8
Tarzia, G.9
Calignano, A.10
Piomelli, D.11
-
195
-
-
20244380014
-
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
-
Sakurai, T., Amemiya, A., Ishii, M., Matsuzaki, I., Chemelli, R.M., Tanaka, H., Williams, S.C., Richarson, J.A., Kozlowski, G.P., Wilson, S., Arch, J.R., Buckingham, R.E., Haynes, A.C., Carr, S.A., Annan, R.S., McNulty, D.E., Liu, W.S., Terrett, J.A., Elshourbagy, N.A., Bergsma, D.J. & Yanagisawa, M. (1998) Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell, 92, 573-585.
-
(1998)
Cell
, vol.92
, pp. 573-585
-
-
Sakurai, T.1
Amemiya, A.2
Ishii, M.3
Matsuzaki, I.4
Chemelli, R.M.5
Tanaka, H.6
Williams, S.C.7
Richarson, J.A.8
Kozlowski, G.P.9
Wilson, S.10
Arch, J.R.11
Buckingham, R.E.12
Haynes, A.C.13
Carr, S.A.14
Annan, R.S.15
McNulty, D.E.16
Liu, W.S.17
Terrett, J.A.18
Elshourbagy, N.A.19
Bergsma, D.J.20
Yanagisawa, M.21
more..
-
196
-
-
84859793552
-
Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions
-
Sasso, O., Bertorelli, R., Bandiera, T., Scarpelli, R., Colombano, G., Armirotti, A., Moreno-Sanz, G., Reggiani, A. & Piomelli, D. (2012) Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions. Pharmacol. Res., 65, 553-563.
-
(2012)
Pharmacol. Res.
, vol.65
, pp. 553-563
-
-
Sasso, O.1
Bertorelli, R.2
Bandiera, T.3
Scarpelli, R.4
Colombano, G.5
Armirotti, A.6
Moreno-Sanz, G.7
Reggiani, A.8
Piomelli, D.9
-
197
-
-
0034740567
-
Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes
-
Savinainen, J.R., Jarvinen, T., Laine, K. & Laitinen, J.T. (2001) Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes. Brit. J. Pharmacol., 134, 664-672.
-
(2001)
Brit. J. Pharmacol.
, vol.134
, pp. 664-672
-
-
Savinainen, J.R.1
Jarvinen, T.2
Laine, K.3
Laitinen, J.T.4
-
198
-
-
0032490395
-
Identification of somatostatin sst2(a) receptor expressing neurones in central regions involved in nociception
-
Schindler, M., Holloway, S., Hathway, G., Woolf, C.J., Humphrey, P.P. & Emson, P.C. (1998) Identification of somatostatin sst2(a) receptor expressing neurones in central regions involved in nociception. Brain Res., 798, 25-35.
-
(1998)
Brain Res.
, vol.798
, pp. 25-35
-
-
Schindler, M.1
Holloway, S.2
Hathway, G.3
Woolf, C.J.4
Humphrey, P.P.5
Emson, P.C.6
-
199
-
-
77956181836
-
Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
-
Schlosburg, J.E., Blankman, J.L., Long, J.Z., Nomura, D.K., Pan, B., Kinsey, S.G., Nguyen, P.T., Ramesh, D., Booker, L., Burston, J.J., Thomas, E.A., Selley, D.E., Sim-Selley, L.J., Liu, Q.S., Lichtman, A.H. & Cravatt, B.F. (2010) Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system. Nat. Neurosci., 13, 1113-1119.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1113-1119
-
-
Schlosburg, J.E.1
Blankman, J.L.2
Long, J.Z.3
Nomura, D.K.4
Pan, B.5
Kinsey, S.G.6
Nguyen, P.T.7
Ramesh, D.8
Booker, L.9
Burston, J.J.10
Thomas, E.A.11
Selley, D.E.12
Sim-Selley, L.J.13
Liu, Q.S.14
Lichtman, A.H.15
Cravatt, B.F.16
-
200
-
-
0021099820
-
Metabolism of N-acylethanolamine phospholipids by a mammalian phosphodiesterase of the phospholipase D type
-
Schmid, P.C., Reddy, P.V., Natarajan, V. & Schmid, H.H. (1983) Metabolism of N-acylethanolamine phospholipids by a mammalian phosphodiesterase of the phospholipase D type. J. Biol. Chem., 258, 9302-9306.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 9302-9306
-
-
Schmid, P.C.1
Reddy, P.V.2
Natarajan, V.3
Schmid, H.H.4
-
201
-
-
80052029740
-
Biochemical characterization and in vitro activity of AZ513, a noncovalent, reversible, and noncompetitive inhibitor of fatty acid amide hydrolase
-
Scott, C.W., Tian, G., Yu, X.H., Paschetto, K.A., Wilkins, D.E., Meury, L., Cao, C.Q., Varnes, J. & Edwards, P.D. (2011) Biochemical characterization and in vitro activity of AZ513, a noncovalent, reversible, and noncompetitive inhibitor of fatty acid amide hydrolase. Eur. J. Pharmacol., 667, 74-79.
-
(2011)
Eur. J. Pharmacol.
, vol.667
, pp. 74-79
-
-
Scott, C.W.1
Tian, G.2
Yu, X.H.3
Paschetto, K.A.4
Wilkins, D.E.5
Meury, L.6
Cao, C.Q.7
Varnes, J.8
Edwards, P.D.9
-
202
-
-
80054990781
-
Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors
-
Serrano, A. & Parsons, L.H. (2011) Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors. Pharmacol. Therapeut., 132, 215-241.
-
(2011)
Pharmacol. Therapeut.
, vol.132
, pp. 215-241
-
-
Serrano, A.1
Parsons, L.H.2
-
203
-
-
0029937282
-
Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures
-
Shen, M., Piser, T.M., Seybold, V.S. & Thayer, S.A. (1996) Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures. J. Neurosci., 16, 4322-4334.
-
(1996)
J. Neurosci.
, vol.16
, pp. 4322-4334
-
-
Shen, M.1
Piser, T.M.2
Seybold, V.S.3
Thayer, S.A.4
-
204
-
-
81055130228
-
The major central endocannabinoid directly acts at GABA(A) receptors
-
Sigel, E., Baur, R., Racz, I., Marazzi, J., Smart, T.G., Zimmer, A. & Gertsch, J. (2011) The major central endocannabinoid directly acts at GABA(A) receptors. Proc. Natl. Acad. Sci. USA, 108, 18150-18155.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 18150-18155
-
-
Sigel, E.1
Baur, R.2
Racz, I.3
Marazzi, J.4
Smart, T.G.5
Zimmer, A.6
Gertsch, J.7
-
205
-
-
33748743637
-
Endocannabinoid biosynthesis proceeding through Glycerophospho-N-Acyl ethanolamine and a role for alpha/beta hydrolase 4 in this pathway
-
Simon, G.M. & Cravatt, B.F. (2006) Endocannabinoid biosynthesis proceeding through Glycerophospho-N-Acyl ethanolamine and a role for alpha/beta hydrolase 4 in this pathway. J. Biol. Chem., 281, 26465-26472.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26465-26472
-
-
Simon, G.M.1
Cravatt, B.F.2
-
206
-
-
77954582423
-
Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo
-
Simon, G.M. & Cravatt, B.F. (2010) Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo. Mol. BioSyst., 6, 1411-1418.
-
(2010)
Mol. BioSyst.
, vol.6
, pp. 1411-1418
-
-
Simon, G.M.1
Cravatt, B.F.2
-
207
-
-
39149110920
-
The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats
-
Sink, K.S., McLaughlin, P.J., Wood, J.A., Brown, C., Fan, P., Vemuri, V.K., Peng, Y., Olszewska, T., Thakur, G.A., Makriyannis, A., Parker, L.A. & Salamone, J.D. (2008) The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats. Neuropsychopharmacol., 33, 946-955.
-
(2008)
Neuropsychopharmacol.
, vol.33
, pp. 946-955
-
-
Sink, K.S.1
McLaughlin, P.J.2
Wood, J.A.3
Brown, C.4
Fan, P.5
Vemuri, V.K.6
Peng, Y.7
Olszewska, T.8
Thakur, G.A.9
Makriyannis, A.10
Parker, L.A.11
Salamone, J.D.12
-
208
-
-
0037062436
-
A missense mutation in human fatty acid amide hydrolase associated with problem drug use
-
Sipe, J.C., Chiang, K., Gerber, A.L., Beutler, E. & Cravatt, B.F. (2002) A missense mutation in human fatty acid amide hydrolase associated with problem drug use. Proc. Natl. Acad. Sci. USA, 99, 8394-8399.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8394-8399
-
-
Sipe, J.C.1
Chiang, K.2
Gerber, A.L.3
Beutler, E.4
Cravatt, B.F.5
-
209
-
-
84893390871
-
-
Bisarylimidazolyl fatty acid amide hydrolase inhibitors. Available online
-
Sit, S. & Xie, K. (2002) Bisarylimidazolyl fatty acid amide hydrolase inhibitors. Available online http://patents.justia.com/patent/20020188009.
-
(2002)
-
-
Sit, S.1
Xie, K.2
-
210
-
-
84893408945
-
-
Oxime carbamoyl fatty acid amide hydrolase inhibitors. Available online
-
Sit, S. & Xie, K. (2003) (Oxime) carbamoyl fatty acid amide hydrolase inhibitors. Available online http://patentscope.wipo.int/search/en/WO2003065989.
-
(2003)
-
-
Sit, S.1
Xie, K.2
-
211
-
-
37249040918
-
Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways
-
Starowicz, K., Maione, S., Cristino, L., Palazzo, E., Marabese, I., Rossi, F., de Novellis, V. & Di Marzo, V. (2007) Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways. J. Neurosci., 27, 13739-13749.
-
(2007)
J. Neurosci.
, vol.27
, pp. 13739-13749
-
-
Starowicz, K.1
Maione, S.2
Cristino, L.3
Palazzo, E.4
Marabese, I.5
Rossi, F.6
de Novellis, V.7
Di Marzo, V.8
-
212
-
-
0032495194
-
Evidence for a role of endogenous cannabinoids in the modulation of acute and tonic pain sensitivity
-
Strangman, N.M., Patrick, S.L., Hohmann, A.G., Tsou, K. & Walker, J.M. (1998) Evidence for a role of endogenous cannabinoids in the modulation of acute and tonic pain sensitivity. Brain Res., 813, 323-328.
-
(1998)
Brain Res.
, vol.813
, pp. 323-328
-
-
Strangman, N.M.1
Patrick, S.L.2
Hohmann, A.G.3
Tsou, K.4
Walker, J.M.5
-
213
-
-
0028970517
-
2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain
-
Sugiura, T., Kondo, S., Sukagawa, A., Nakane, S., Shinoda, A., Itoh, K., Yamashita, A. & Waku, K. (1995) 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. Biochem. Bioph. Res. Co., 215, 89-97.
-
(1995)
Biochem. Bioph. Res. Co.
, vol.215
, pp. 89-97
-
-
Sugiura, T.1
Kondo, S.2
Sukagawa, A.3
Nakane, S.4
Shinoda, A.5
Itoh, K.6
Yamashita, A.7
Waku, K.8
-
214
-
-
0034614374
-
Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells
-
Sugiura, T., Kondo, S., Kishimoto, S., Miyashita, T., Nakane, S., Kodaka, T., Suhara, Y., Takayama, H. & Waku, K. (2000) Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells. J. Biol. Chem., 275, 605-612.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 605-612
-
-
Sugiura, T.1
Kondo, S.2
Kishimoto, S.3
Miyashita, T.4
Nakane, S.5
Kodaka, T.6
Suhara, Y.7
Takayama, H.8
Waku, K.9
-
215
-
-
0036019386
-
Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance
-
Sugiura, T., Kobayashi, Y., Oka, S. & Waku, K. (2002) Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. Prostag. Leukotr. Ess., 66, 173-192.
-
(2002)
Prostag. Leukotr. Ess.
, vol.66
, pp. 173-192
-
-
Sugiura, T.1
Kobayashi, Y.2
Oka, S.3
Waku, K.4
-
216
-
-
3042737612
-
Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D
-
Sun, Y.X., Tsuboi, K., Okamoto, Y., Tonai, T., Murakami, M., Kudo, I. & Ueda, N. (2004) Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D. Biochem. J., 380, 749-756.
-
(2004)
Biochem. J.
, vol.380
, pp. 749-756
-
-
Sun, Y.X.1
Tsuboi, K.2
Okamoto, Y.3
Tonai, T.4
Murakami, M.5
Kudo, I.6
Ueda, N.7
-
217
-
-
0029930179
-
Somatostatin receptor subtypes SSTR2 and SSTR5 couple negatively to an L-type Ca2+ current in the pituitary cell line AtT-20
-
Tallent, M., Liapakis, G., O'Carroll, A.M., Lolait, S.J., Dichter, M. & Reisine, T. (1996) Somatostatin receptor subtypes SSTR2 and SSTR5 couple negatively to an L-type Ca2+ current in the pituitary cell line AtT-20. Neuroscience, 71, 1073-1081.
-
(1996)
Neuroscience
, vol.71
, pp. 1073-1081
-
-
Tallent, M.1
Liapakis, G.2
O'Carroll, A.M.3
Lolait, S.J.4
Dichter, M.5
Reisine, T.6
-
218
-
-
0035960059
-
Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites
-
Tamaru, Y., Nomura, S., Mizuno, N. & Shigemoto, R. (2001) Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites. Neuroscience, 106, 481-503.
-
(2001)
Neuroscience
, vol.106
, pp. 481-503
-
-
Tamaru, Y.1
Nomura, S.2
Mizuno, N.3
Shigemoto, R.4
-
219
-
-
0028287446
-
Histamine-induced modulation of nociceptive responses
-
Thoburn, K.K., Hough, L.B., Nalwalk, J.W. & Mischler, S.A. (1994) Histamine-induced modulation of nociceptive responses. Pain, 58, 29-37.
-
(1994)
Pain
, vol.58
, pp. 29-37
-
-
Thoburn, K.K.1
Hough, L.B.2
Nalwalk, J.W.3
Mischler, S.A.4
-
220
-
-
0030044427
-
Suppression of noxious stimulus-evoked expression of Fos protein-like immunoreactivity in rat spinal cord by a selective cannabinoid agonist
-
Tsou, K., Lowitz, K.A., Hohmann, A.G., Martin, W.J., Hathaway, C.B., Bereiter, D.A. & Walker, J.M. (1996) Suppression of noxious stimulus-evoked expression of Fos protein-like immunoreactivity in rat spinal cord by a selective cannabinoid agonist. Neuroscience, 70, 791-798.
-
(1996)
Neuroscience
, vol.70
, pp. 791-798
-
-
Tsou, K.1
Lowitz, K.A.2
Hohmann, A.G.3
Martin, W.J.4
Hathaway, C.B.5
Bereiter, D.A.6
Walker, J.M.7
-
221
-
-
0031929438
-
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
-
Tsou, K., Brown, S., Sanudo-Pena, M.C., Mackie, K. & Walker, J.M. (1998a) Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience, 83, 393-411.
-
(1998)
Neuroscience
, vol.83
, pp. 393-411
-
-
Tsou, K.1
Brown, S.2
Sanudo-Pena, M.C.3
Mackie, K.4
Walker, J.M.5
-
222
-
-
0032476070
-
Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry
-
Tsou, K., Nogueron, M.I., Muthian, S., Sanudo-Pena, M.C., Hillard, C.J., Deutsch, D.G. & Walker, J.M. (1998b) Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry. Neurosci. Lett., 254, 137-140.
-
(1998)
Neurosci. Lett.
, vol.254
, pp. 137-140
-
-
Tsou, K.1
Nogueron, M.I.2
Muthian, S.3
Sanudo-Pena, M.C.4
Hillard, C.J.5
Deutsch, D.G.6
Walker, J.M.7
-
223
-
-
67649448978
-
Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system
-
Tsujino, N. & Sakurai, T. (2009) Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system. Pharmacol. Rev., 61, 162-176.
-
(2009)
Pharmacol. Rev.
, vol.61
, pp. 162-176
-
-
Tsujino, N.1
Sakurai, T.2
-
224
-
-
67650564947
-
Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors
-
Turu, G., Varnai, P., Gyombolai, P., Szidonya, L., Offertaler, L., Bagdy, G., Kunos, G. & Hunyady, L. (2009) Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors. J. Biol. Chem., 284, 16914-16921.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 16914-16921
-
-
Turu, G.1
Varnai, P.2
Gyombolai, P.3
Szidonya, L.4
Offertaler, L.5
Bagdy, G.6
Kunos, G.7
Hunyady, L.8
-
225
-
-
0034095022
-
Reduction of stress-induced analgesia but not of exogenous opioid effects in mice lacking CB1 receptors
-
Valverde, O., Ledent, C., Beslot, F., Parmentier, M. & Roques, B.P. (2000) Reduction of stress-induced analgesia but not of exogenous opioid effects in mice lacking CB1 receptors. Eur. J. Neurosci., 12, 533-539.
-
(2000)
Eur. J. Neurosci.
, vol.12
, pp. 533-539
-
-
Valverde, O.1
Ledent, C.2
Beslot, F.3
Parmentier, M.4
Roques, B.P.5
-
226
-
-
26844504226
-
Identification and functional characterization of brainstem cannabinoid CB2 receptors
-
Van Sickle, M.D., Duncan, M., Kingsley, P.J., Mouihate, A., Urbani, P., Mackie, K., Stella, N., Makriyannis, A., Piomelli, D., Davison, J.S., Marnett, L.J., Di Marzo, V., Pittman, Q.J., Patel, K.D. & Sharkey, K.A. (2005) Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science, 310, 329-332.
-
(2005)
Science
, vol.310
, pp. 329-332
-
-
Van Sickle, M.D.1
Duncan, M.2
Kingsley, P.J.3
Mouihate, A.4
Urbani, P.5
Mackie, K.6
Stella, N.7
Makriyannis, A.8
Piomelli, D.9
Davison, J.S.10
Marnett, L.J.11
Di Marzo, V.12
Pittman, Q.J.13
Patel, K.D.14
Sharkey, K.A.15
-
227
-
-
23744501056
-
Inhibition of fatty acid amide hydrolase and monoacylglycerol lipase by the anandamide uptake inhibitor VDM11: evidence that VDM11 acts as an FAAH substrate
-
Vandevoorde, S. & Fowler, C.J. (2005) Inhibition of fatty acid amide hydrolase and monoacylglycerol lipase by the anandamide uptake inhibitor VDM11: evidence that VDM11 acts as an FAAH substrate. Brit. J. Pharmacol., 145, 885-893.
-
(2005)
Brit. J. Pharmacol.
, vol.145
, pp. 885-893
-
-
Vandevoorde, S.1
Fowler, C.J.2
-
228
-
-
0033952656
-
Actions of cannabinoids on membrane properties and synaptic transmission in rat periaqueductal gray neurons in vitro
-
Vaughan, C.W., Connor, M., Bagley, E.E. & Christie, M.J. (2000) Actions of cannabinoids on membrane properties and synaptic transmission in rat periaqueductal gray neurons in vitro. Mol. Pharmacol., 57, 288-295.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 288-295
-
-
Vaughan, C.W.1
Connor, M.2
Bagley, E.E.3
Christie, M.J.4
-
229
-
-
33646365073
-
Characterization of chronic constriction of the saphenous nerve, a model of neuropathic pain in mice showing rapid molecular and electrophysiological changes
-
Walczak, J.S., Pichette, V., Leblond, F., Desbiens, K. & Beaulieu, P. (2006) Characterization of chronic constriction of the saphenous nerve, a model of neuropathic pain in mice showing rapid molecular and electrophysiological changes. J. Neurosci. Res., 83, 1310-1322.
-
(2006)
J. Neurosci. Res.
, vol.83
, pp. 1310-1322
-
-
Walczak, J.S.1
Pichette, V.2
Leblond, F.3
Desbiens, K.4
Beaulieu, P.5
-
230
-
-
0034891711
-
Cannabinoids and pain
-
Walker, J.M., Strangman, N.M. & Huang, S.M. (2001) Cannabinoids and pain. Pain Res. Manag., 6, 74-79.
-
(2001)
Pain Res. Manag.
, vol.6
, pp. 74-79
-
-
Walker, J.M.1
Strangman, N.M.2
Huang, S.M.3
-
231
-
-
0037036436
-
Astrocytes in culture produce anandamide and other acylethanolamides
-
Walter, L., Franklin, A., Witting, A., Moller, T. & Stella, N. (2002) Astrocytes in culture produce anandamide and other acylethanolamides. J. Biol. Chem., 277, 20869-20876.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 20869-20876
-
-
Walter, L.1
Franklin, A.2
Witting, A.3
Moller, T.4
Stella, N.5
-
232
-
-
0034708537
-
Antinociceptive effects induced by intra-periaqueductal grey administration of neuropeptide Y in rats
-
Wang, J.Z., Lundeberg, T. & Yu, L. (2000) Antinociceptive effects induced by intra-periaqueductal grey administration of neuropeptide Y in rats. Brain Res., 859, 361-363.
-
(2000)
Brain Res.
, vol.859
, pp. 361-363
-
-
Wang, J.Z.1
Lundeberg, T.2
Yu, L.3
-
233
-
-
0035793994
-
Anti-nociceptive effect of neuropeptide Y in periaqueductal grey in rats with inflammation
-
Wang, J.Z., Lundeberg, T. & Yu, L.C. (2001) Anti-nociceptive effect of neuropeptide Y in periaqueductal grey in rats with inflammation. Brain Res., 893, 264-267.
-
(2001)
Brain Res.
, vol.893
, pp. 264-267
-
-
Wang, J.Z.1
Lundeberg, T.2
Yu, L.C.3
-
234
-
-
13244273392
-
Persistent pain and stress activate pain-inhibitory orexin pathways
-
Watanabe, S., Kuwaki, T., Yanagisawa, M., Fukuda, Y. & Shimoyama, M. (2005) Persistent pain and stress activate pain-inhibitory orexin pathways. NeuroReport, 16, 5-8.
-
(2005)
NeuroReport
, vol.16
, pp. 5-8
-
-
Watanabe, S.1
Kuwaki, T.2
Yanagisawa, M.3
Fukuda, Y.4
Shimoyama, M.5
-
235
-
-
0031842048
-
A differential modulation of allodynia, hyperalgesia and nociception by neuropeptide FF in the periaqueductal gray of neuropathic rats: interactions with morphine and naloxone
-
Wei, H., Panula, P. & Pertovaara, A. (1998) A differential modulation of allodynia, hyperalgesia and nociception by neuropeptide FF in the periaqueductal gray of neuropathic rats: interactions with morphine and naloxone. Neuroscience, 86, 311-319.
-
(1998)
Neuroscience
, vol.86
, pp. 311-319
-
-
Wei, H.1
Panula, P.2
Pertovaara, A.3
-
236
-
-
33845981826
-
A second fatty acid amide hydrolase with variable distribution among placental mammals
-
Wei, B.Q., Mikkelsen, T.S., McKinney, M.K., Lander, E.S. & Cravatt, B.F. (2006) A second fatty acid amide hydrolase with variable distribution among placental mammals. J. Biol. Chem., 281, 36569-36578.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 36569-36578
-
-
Wei, B.Q.1
Mikkelsen, T.S.2
McKinney, M.K.3
Lander, E.S.4
Cravatt, B.F.5
-
237
-
-
28844447455
-
A role for cannabinoid receptors, but not endogenous opioids, in the antinociceptive activity of the CB2-selective agonist, GW405833
-
Whiteside, G.T., Gottshall, S.L., Boulet, J.M., Chaffer, S.M., Harrison, J.E., Pearson, M.S., Turchin, P.I., Mark, L., Garrison, A.E. & Valenzano, K.J. (2005) A role for cannabinoid receptors, but not endogenous opioids, in the antinociceptive activity of the CB2-selective agonist, GW405833. Eur. J. Pharmacol., 528, 65-72.
-
(2005)
Eur. J. Pharmacol.
, vol.528
, pp. 65-72
-
-
Whiteside, G.T.1
Gottshall, S.L.2
Boulet, J.M.3
Chaffer, S.M.4
Harrison, J.E.5
Pearson, M.S.6
Turchin, P.I.7
Mark, L.8
Garrison, A.E.9
Valenzano, K.J.10
-
238
-
-
84872166758
-
Postsynaptic mGluR mediated excitation of neurons in midbrain periaqueductal grey
-
Wilson-Poe, A.R., Mitchell, V.A. & Vaughan, C.W. (2013) Postsynaptic mGluR mediated excitation of neurons in midbrain periaqueductal grey. Neuropharmacology, 66, 348-354.
-
(2013)
Neuropharmacology
, vol.66
, pp. 348-354
-
-
Wilson-Poe, A.R.1
Mitchell, V.A.2
Vaughan, C.W.3
-
239
-
-
84870559880
-
Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat
-
Woodhams, S.G., Wong, A., Barrett, D.A., Bennett, A.J., Chapman, V. & Alexander, S.P. (2012) Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat. Brit. J. Pharmacol., 167, 1609-1619.
-
(2012)
Brit. J. Pharmacol.
, vol.167
, pp. 1609-1619
-
-
Woodhams, S.G.1
Wong, A.2
Barrett, D.A.3
Bennett, A.J.4
Chapman, V.5
Alexander, S.P.6
-
240
-
-
0025353131
-
Cholinergic neurons of the feline pontomesencephalon. II. Ascending anatomical projections
-
Woolf, N.J., Harrison, J.B. & Buchwald, J.S. (1990) Cholinergic neurons of the feline pontomesencephalon. II. Ascending anatomical projections. Brain Res., 520, 55-72.
-
(1990)
Brain Res.
, vol.520
, pp. 55-72
-
-
Woolf, N.J.1
Harrison, J.B.2
Buchwald, J.S.3
-
241
-
-
24044458606
-
Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons
-
Wotherspoon, G., Fox, A., McIntyre, P., Colley, S., Bevan, S. & Winter, J. (2005) Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons. Neuroscience, 135, 235-245.
-
(2005)
Neuroscience
, vol.135
, pp. 235-245
-
-
Wotherspoon, G.1
Fox, A.2
McIntyre, P.3
Colley, S.4
Bevan, S.5
Winter, J.6
-
242
-
-
77955861834
-
Role of midbrain periaqueductal gray P2X3 receptors in electroacupuncture-mediated endogenous pain modulatory systems
-
Xiao, Z., Ou, S., He, W.J., Zhao, Y.D., Liu, X.H. & Ruan, H.Z. (2010) Role of midbrain periaqueductal gray P2X3 receptors in electroacupuncture-mediated endogenous pain modulatory systems. Brain Res., 1330, 31-44.
-
(2010)
Brain Res.
, vol.1330
, pp. 31-44
-
-
Xiao, Z.1
Ou, S.2
He, W.J.3
Zhao, Y.D.4
Liu, X.H.5
Ruan, H.Z.6
-
243
-
-
46749122290
-
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia
-
Xie, X., Wisor, J.P., Hara, J., Crowder, T.L., LeWinter, R., Khroyan, T.V., Yamanaka, A., Diano, S., Horvath, T.L., Sakurai, T., Toll, L. & Kilduff, T.S. (2008) Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. J. Clin. Invest., 118, 2471-2481.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2471-2481
-
-
Xie, X.1
Wisor, J.P.2
Hara, J.3
Crowder, T.L.4
LeWinter, R.5
Khroyan, T.V.6
Yamanaka, A.7
Diano, S.8
Horvath, T.L.9
Sakurai, T.10
Toll, L.11
Kilduff, T.S.12
-
244
-
-
33846455132
-
TRPV1 receptor mediates glutamatergic synaptic input to dorsolateral periaqueductal gray (dl-PAG) neurons
-
Xing, J. & Li, J. (2007) TRPV1 receptor mediates glutamatergic synaptic input to dorsolateral periaqueductal gray (dl-PAG) neurons. J. Neurophysiol., 97, 503-511.
-
(2007)
J. Neurophysiol.
, vol.97
, pp. 503-511
-
-
Xing, J.1
Li, J.2
-
245
-
-
43049098978
-
Purinergic P2X receptors presynaptically increase glutamatergic synaptic transmission in dorsolateral periaqueductal gray
-
Xing, J., Lu, J. & Li, J. (2008) Purinergic P2X receptors presynaptically increase glutamatergic synaptic transmission in dorsolateral periaqueductal gray. Brain Res., 1208, 46-55.
-
(2008)
Brain Res.
, vol.1208
, pp. 46-55
-
-
Xing, J.1
Lu, J.2
Li, J.3
-
246
-
-
79957998368
-
Oxytocin in the periaqueductal grey regulates nociception in the rat
-
Yang, J., Li, P., Liang, J.Y., Pan, Y.J., Yan, X.Q., Yan, F.L., Hao, F., Zhang, X.Y., Zhang, J., Qiu, P.Y. & Wang, D.X. (2011) Oxytocin in the periaqueductal grey regulates nociception in the rat. Regul. Peptides, 169, 39-42.
-
(2011)
Regul. Peptides
, vol.169
, pp. 39-42
-
-
Yang, J.1
Li, P.2
Liang, J.Y.3
Pan, Y.J.4
Yan, X.Q.5
Yan, F.L.6
Hao, F.7
Zhang, X.Y.8
Zhang, J.9
Qiu, P.Y.10
Wang, D.X.11
-
247
-
-
0038684167
-
Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models
-
Zhang, J., Hoffert, C., Vu, H.K., Groblewski, T., Ahmad, S. & O'Donnell, D. (2003) Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models. Eur. J. Neurosci., 17, 2750-2754.
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 2750-2754
-
-
Zhang, J.1
Hoffert, C.2
Vu, H.K.3
Groblewski, T.4
Ahmad, S.5
O'Donnell, D.6
-
248
-
-
0033545866
-
Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
-
Zimmer, A., Zimmer, A.M., Hohmann, A.G., Herkenham, M. & Bonner, T.I. (1999) Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc. Natl. Acad. Sci. USA, 96, 5780-5785.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5780-5785
-
-
Zimmer, A.1
Zimmer, A.M.2
Hohmann, A.G.3
Herkenham, M.4
Bonner, T.I.5
-
249
-
-
0033614984
-
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
-
Zygmunt, P.M., Petersson, J., Andersson, D.A., Chuang, H., Sorgard, M., Di Marzo, V., Julius, D. & Hogestatt, E.D. (1999) Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature, 400, 452-457.
-
(1999)
Nature
, vol.400
, pp. 452-457
-
-
Zygmunt, P.M.1
Petersson, J.2
Andersson, D.A.3
Chuang, H.4
Sorgard, M.5
Di Marzo, V.6
Julius, D.7
Hogestatt, E.D.8
|