Substance P drives endocannabinoid-mediated disinhibition in a midbrain descending analgesic pathway

Journal of Neuroscience

Volumn 29, Issue 22, 2009, Pages 7220-7229

  Drew, Geoffrey M ^a,b   Lau, Benjamin K ^a   Vaughan, Christopher W ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2 ARACHIDONOYLGLYCEROL; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; ADENOSINE A1 RECEPTOR ANTAGONIST; CANNABINOID 1 RECEPTOR ANTAGONIST; DELTA OPIATE RECEPTOR ANTAGONIST; ENDOCANNABINOID; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; LIPOPROTEIN LIPASE; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; MU OPIATE RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SEROTONIN 1 ANTAGONIST; SUBSTANCE P;

ACTION POTENTIAL; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EVOKED RESPONSE; EXCITATION; FEMALE; GABAERGIC TRANSMISSION; MALE; MEDULLA OBLONGATA; MESENCEPHALON; NERVE CELL; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; SYNAPTIC TRANSMISSION;

AFFERENT PATHWAYS; ANIMALS; ANIMALS, NEWBORN; DRUG INTERACTIONS; ELECTRIC STIMULATION; ENDOCANNABINOIDS; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGENTS; FEMALE; GLUTAMIC ACID; MALE; MEDULLA OBLONGATA; NEURONS; PATCH-CLAMP TECHNIQUES; PERIAQUEDUCTAL GRAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, TACHYKININ; SIGNAL TRANSDUCTION; SUBSTANCE P; SYNAPTIC TRANSMISSION;

EID: 66749083837     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4362-08.2009     Document Type: Article

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