Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 316, Issue 3, 2006, Pages 969-982

  Maione, Sabatino ^a   Bisogno, Tiziana ^b   De Novellis, Vito ^a   Palazzo, Enza ^a   Cristino, Luigia ^b   Valenti, Marta ^b   Petrosino, Stefania ^b   Guglielmotti, Vittorio ^b   Rossi, Francesco ^a   Di Marzo, Vincenzo ^b  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 ARACHIDONOYLGLYCEROL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ANANDAMIDE; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR AGONIST; CAPSAICIN; CARBAMIC ACID DERIVATIVE; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; ENDOCANNABINOID; FATTY ACID AMIDASE; HYDROLASE INHIBITOR; UNCLASSIFIED DRUG; URB 597; VANILLOID RECEPTOR 1;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL ACTIVITY; CELL STIMULATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; HEALTH STATUS; IMMUNOHISTOCHEMISTRY; MALE; NOCICEPTION; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TAIL FLICK TEST; TEMPERATURE;

AMIDOHYDROLASES; ANALGESIA; ANIMALS; BENZAMIDES; CARBAMATES; ENDOCANNABINOIDS; IMMUNOHISTOCHEMISTRY; MALE; MEDULLA OBLONGATA; MORPHOLINES; NAPHTHALENES; PAIN; PERIAQUEDUCTAL GRAY; RATS; RATS, WISTAR; RECEPTOR, CANNABINOID, CB1; TRPV CATION CHANNELS;

EID: 33644766044     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.093286     Document Type: Article

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