메뉴 건너뛰기




Volumn 153, Issue 9, 2012, Pages 1785-1786

Inhibitors of endocannabinoid breakdown for pain: Not so FA(AH)cile, after all

Author keywords

[No Author keywords available]

Indexed keywords

ANANDAMIDE; CANNABINOID 1 RECEPTOR; DRONABINOL; ENDOCANNABINOID; FATTY ACID AMIDASE; FATTY ACID AMIDASE INHIBITOR; NAPROXEN; PF 04457845; PLACEBO; UNCLASSIFIED DRUG;

EID: 84864624995     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2012.06.016     Document Type: Editorial
Times cited : (33)

References (14)
  • 2
    • 80053943575 scopus 로고    scopus 로고
    • Nonopioid placebo analgesia is mediated by CB1 cannabinoid receptors
    • F. Benedetti, M. Amanzio, R. Rosato, and C. Blanchard Nonopioid placebo analgesia is mediated by CB1 cannabinoid receptors Nat Med 17 2011 1228 1230
    • (2011) Nat Med , vol.17 , pp. 1228-1230
    • Benedetti, F.1    Amanzio, M.2    Rosato, R.3    Blanchard, C.4
  • 3
    • 77952885551 scopus 로고    scopus 로고
    • The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl- serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice
    • B. Costa, I. Bettoni, S. Petrosino, F. Comelli, G. Giagnoni, and V. Di Marzo The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl- serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice Pharmacol Res 61 2010 537 546
    • (2010) Pharmacol Res , vol.61 , pp. 537-546
    • Costa, B.1    Bettoni, I.2    Petrosino, S.3    Comelli, F.4    Giagnoni, G.5    Di Marzo, V.6
  • 4
    • 0029904838 scopus 로고    scopus 로고
    • Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
    • B.F. Cravatt, D.K. Giang, S.P. Mayfield, D.L. Boger, R.A. Lerner, and N.B. Gilula Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides Nature 384 1996 83 87
    • (1996) Nature , vol.384 , pp. 83-87
    • Cravatt, B.F.1    Giang, D.K.2    Mayfield, S.P.3    Boger, D.L.4    Lerner, R.A.5    Gilula, N.B.6
  • 5
    • 84857382479 scopus 로고    scopus 로고
    • Discovery of prostamide F2α and its role in inflammatory pain and dorsal horn nociceptive neuron hyperexcitability
    • L. Gatta, F. Piscitelli, C. Giordano, S. Boccella, A. Lichtman, S. Maione, and V. Di Marzo Discovery of prostamide F2α and its role in inflammatory pain and dorsal horn nociceptive neuron hyperexcitability PLoS One 7 2012 1 12
    • (2012) PLoS One , vol.7 , pp. 1-12
    • Gatta, L.1    Piscitelli, F.2    Giordano, C.3    Boccella, S.4    Lichtman, A.5    Maione, S.6    Di Marzo, V.7
  • 7
    • 84857125719 scopus 로고    scopus 로고
    • Contributions of endocannabinoid signaling to psychiatric disorders in humans: Genetic and biochemical evidence
    • C.J. Hillard, K.M. Weinlander, and K.L. Stuhr Contributions of endocannabinoid signaling to psychiatric disorders in humans: genetic and biochemical evidence Neuroscience 204 2012 207 229
    • (2012) Neuroscience , vol.204 , pp. 207-229
    • Hillard, C.J.1    Weinlander, K.M.2    Stuhr, K.L.3
  • 8
    • 24744469860 scopus 로고    scopus 로고
    • Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system
    • E.D. Högestätt, B.A. Jönsson, A. Ermund, D.A. Andersson, H. Björk, J.P. Alexander, B.F. Cravatt, A.I. Basbaum, and P.M. Zygmunt Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system J Biol Chem 280 2005 31405 31412
    • (2005) J Biol Chem , vol.280 , pp. 31405-31412
    • Högestätt, E.D.1    Jönsson, B.A.2    Ermund, A.3    Andersson, D.A.4    Björk, H.5    Alexander, J.P.6    Cravatt, B.F.7    Basbaum, A.I.8    Zygmunt, P.M.9
  • 9
    • 84864577250 scopus 로고    scopus 로고
    • An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee
    • J.P. Huggins, T.S. Smart, S. Langman, L. Taylor, and T. Young An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee PAIN® 153 2012 1837 1846
    • (2012) PAIN® , vol.153 , pp. 1837-1846
    • Huggins, J.P.1    Smart, T.S.2    Langman, S.3    Taylor, L.4    Young, T.5
  • 10
    • 74549185125 scopus 로고    scopus 로고
    • FAAH and MAGL inhibitors: Therapeutic opportunities from regulating endocannabinoid levels
    • S. Petrosino, and V. Di Marzo FAAH and MAGL inhibitors: therapeutic opportunities from regulating endocannabinoid levels Curr Opin Investig Drugs 11 2010 51 62
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 51-62
    • Petrosino, S.1    Di Marzo, V.2
  • 11
    • 84862077780 scopus 로고    scopus 로고
    • "redundancy" of endocannabinoid inactivation: New challenges and opportunities for pain control
    • doi:10.1021/cn300015x in press
    • Piscitelli F, Di Marzo V. "Redundancy" of endocannabinoid inactivation: new challenges and opportunities for pain control. ACS Chem Neurosci, in press, http://dx.doi.org/10.1021/cn300015x.
    • ACS Chem Neurosci
    • Piscitelli, F.1    Di Marzo, V.2
  • 12
    • 84859324853 scopus 로고    scopus 로고
    • Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain
    • B.P. Roques, M.C. Fournié-Zaluski, and M. Wurm Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain Nat Rev Drug Discov 11 2012 292 310
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 292-310
    • Roques, B.P.1    Fournié-Zaluski, M.C.2    Wurm, M.3
  • 13
    • 79960043805 scopus 로고    scopus 로고
    • Cannabinoid 1 (CB1) receptor-pharmacology, role in pain and recent developments in emerging CB1 agonists
    • R. Talwar, and V.K. Potluri Cannabinoid 1 (CB1) receptor-pharmacology, role in pain and recent developments in emerging CB1 agonists CNS Neurol Disord Drug Targets 10 2011 536 544
    • (2011) CNS Neurol Disord Drug Targets , vol.10 , pp. 536-544
    • Talwar, R.1    Potluri, V.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.