The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 52, 2005, Pages 19144-19149

  Lauckner, Jane E ^a   Hille, Bertil ^a   Mackie, Ken ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Aminoalkylindole; Inositol phosphate; Neurons; Phospholipase C

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 ARACHIDONOYLGLYCEROL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CANNABIDIOL; CANNABINOID 1 RECEPTOR; DANTROLENE; DEXANABINOL; FURA 2; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROQUINONE; HYDROQUINONE DERIVATIVE; INDOLE DERIVATIVE; INOSITOL PHOSPHATE; METHANANDAMIDE; PERTUSSIS TOXIN; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; PYRIDINIUM DERIVATIVE; RIMONABANT; THAPSIGARGIN; UNCLASSIFIED DRUG; XESTOSPONGIN D;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; EMBRYO; HIPPOCAMPUS; HUMAN; HUMAN CELL; NERVE CELL; PHOTOMETRY; PRIORITY JOURNAL;

ANALGESICS; ANIMALS; ARACHIDONIC ACIDS; CALCIUM; CANNABINOIDS; CELL LINE; CYCLOHEXANOLS; CYTOPLASM; DNA, COMPLEMENTARY; ENDOPLASMIC RETICULUM; EXCITATORY AMINO ACID ANTAGONISTS; FLUORESCENT DYES; FURA-2; GLYCERIDES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HIPPOCAMPUS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MORPHOLINES; NAPHTHALENES; NEURONS; PERTUSSIS TOXIN; PHOSPHOLIPASE C; PIPERIDINES; PROTEIN BINDING; PROTEIN CONFORMATION; PYRAZOLES; RATS; RECEPTOR, CANNABINOID, CB1; RYANODINE; TETRAHYDROCANNABINOL; TIME FACTORS;

CANNABIS;

EID: 30044435435     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0509588102     Document Type: Article

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