An endocannabinoid mechanism for stress-induced analgesia

Nature

Volumn 435, Issue 7045, 2005, Pages 1108-1112

  Hohmann, Andrea G ^a   Suplita, Richard L ^a   Bolton, Nathan M ^a   Neely, Mark H ^a   Fegley, Darren ^b   Mangieri, Regina ^b   Krey, Jocelyn F ^c   Walker, J Michael ^c   Holmes, Philip V ^a   Crystal, Jonathon D ^a   Duranti, Andrea ^d   Tontini, Andrea ^d   Mor, Marco ^e   Tarzia, Giorgio ^d   Piomelli, Daniele ^b  

^a University of Georgia ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BROWN UNIVERSITY   (United States)

^d UNIVERSITY OF URBINO   (Italy)

^e UNIVERSITY OF PARMA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; DISEASES; FATTY ACIDS; GLYCEROL; LIPIDS; NEUROPHYSIOLOGY; STRESSES;

ANALGESIA; BRAIN PATHWAYS; HYDROLASE; LIPASE;

MEDICAL PROBLEMS;

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 2 ARACHIDONOYLGLYCEROL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; ACYLGLYCEROL LIPASE; ANANDAMIDE; BIPHENYL 3 YL CARBAMIC ACID CYCLOHEXYL ESTER; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR AGONIST; CANNABINOID RECEPTOR ANTAGONIST; CARBAMIC ACID DERIVATIVE; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; ENDOCANNABINOID; ENZYME INHIBITOR; FATTY ACID AMIDASE; MORPHINE; NALTREXONE; OPIATE; OPIATE ANTAGONIST; RIMONABANT; SR 141617A; UNCLASSIFIED DRUG; URB 524; URB 602;

MEDICINE;

ADOLESCENT; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; DRUG TARGETING; DRUG TOLERANCE; ENZYME INHIBITION; INTRACEREBRAL DRUG ADMINISTRATION; MALE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; STRESS; STRESS INDUCED ANALGESIA;

ANALGESIA; ANIMALS; ARACHIDONIC ACIDS; BIOLOGICAL TRANSPORT; BIPHENYL COMPOUNDS; ENDOCANNABINOIDS; GLYCERIDES; HYDROLYSIS; MALE; MESENCEPHALON; MONOACYLGLYCEROL LIPASES; POLYUNSATURATED ALKAMIDES; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTOR, CANNABINOID, CB1; STRESS;

CANNABIS SATIVA;

EID: 21344444379     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03658     Document Type: Article

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