메뉴 건너뛰기




Volumn 61, Issue 1, 2004, Pages 149-160

The endogenous cannabinoid system and its role in nociceptive behavior

Author keywords

Agonist; Antagonist; Cannabinoid; CB1 receptor; CB2 receptor; Endocannabinoid; Fatty acid amide hydrolase; Inhibitor; Pain

Indexed keywords

ANANDAMIDE; CANNABINOID; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABIS; ETHANOLAMINE; FATTY ACID AMIDASE; G PROTEIN COUPLED RECEPTOR; MONOACYLGLYCEROL; TETRAHYDROCANNABINOL;

EID: 4644372326     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.20080     Document Type: Review
Times cited : (179)

References (109)
  • 1
    • 0034638450 scopus 로고    scopus 로고
    • Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons
    • Ahluwalia J, Urban L, Capogna M, Bevan S, Nagy I. 2000. Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons. Neuroscience 100:685-688.
    • (2000) Neuroscience , vol.100 , pp. 685-688
    • Ahluwalia, J.1    Urban, L.2    Capogna, M.3    Bevan, S.4    Nagy, I.5
  • 2
    • 0037330445 scopus 로고    scopus 로고
    • Intrathecally applied fluribiprofen produces an endocannabinoid-dependent antinociception in the rat formalin test
    • Ates M, Hamza M, Seidel K, Kotalla CE, Ledent C, Guhring H. 2003. Intrathecally applied fluribiprofen produces an endocannabinoid-dependent antinociception in the rat formalin test. Eur J Neurosci 17:597-604.
    • (2003) Eur J Neurosci , vol.17 , pp. 597-604
    • Ates, M.1    Hamza, M.2    Seidel, K.3    Kotalla, C.E.4    Ledent, C.5    Guhring, H.6
  • 3
    • 0033528763 scopus 로고    scopus 로고
    • Characterization of the hypnotic properties of oleamide
    • Basile AS, Hanus L, Mendelson WB. 1999. Characterization of the hypnotic properties of oleamide. Neuroreport 10:947-951.
    • (1999) Neuroreport , vol.10 , pp. 947-951
    • Basile, A.S.1    Hanus, L.2    Mendelson, W.B.3
  • 5
    • 0030865871 scopus 로고    scopus 로고
    • Functional role of high-affinity anandamide transport, as revealed by selective inhibition
    • Beltramo M, Stella N, Calignano A, Lin SY, Makriyannis A, Piomelli D. 1997. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. Science 277:1094-1097.
    • (1997) Science , vol.277 , pp. 1094-1097
    • Beltramo, M.1    Stella, N.2    Calignano, A.3    Lin, S.Y.4    Makriyannis, A.5    Piomelli, D.6
  • 8
    • 0034951162 scopus 로고    scopus 로고
    • The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain
    • Bridges D, Ahmand K, Rice AS. 2001. The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain. Br J Pharmacol 133:586-594.
    • (2001) Br J Pharmacol , vol.133 , pp. 586-594
    • Bridges, D.1    Ahmand, K.2    Rice, A.S.3
  • 9
    • 0031033841 scopus 로고    scopus 로고
    • Occurence and biosynthesis of endogenous cannabinoid precursor, N-arachidonyl phosphatidylethanolamine, in rat brain
    • Cadas H, di Tomaso E, Piomelli D. 1997. Occurence and biosynthesis of endogenous cannabinoid precursor, N-arachidonyl phosphatidylethanolamine, in rat brain. J Neurosci 17:1226-1242.
    • (1997) J Neurosci , vol.17 , pp. 1226-1242
    • Cadas, H.1    Di Tomaso, E.2    Piomelli, D.3
  • 10
    • 0032537734 scopus 로고    scopus 로고
    • Control of pain initiation by endogenous cannabinoids
    • Calignano A, La Rana G, Giuffrida A, Piomelli D. 1998. Control of pain initiation by endogenous cannabinoids. Nature 394:277-281.
    • (1998) Nature , vol.394 , pp. 277-281
    • Calignano, A.1    La Rana, G.2    Giuffrida, A.3    Piomelli, D.4
  • 11
    • 0032588146 scopus 로고    scopus 로고
    • The cannabinoid CB1 receptor antagonist, SR141716A, selectively facilitates nociceptive responses of dorsal horn neurones in the rat
    • Chapman V. 1999. The cannabinoid CB1 receptor antagonist, SR141716A, selectively facilitates nociceptive responses of dorsal horn neurones in the rat. Br J Pharmacol 127:1765-1767.
    • (1999) Br J Pharmacol , vol.127 , pp. 1765-1767
    • Chapman, V.1
  • 12
    • 0034778455 scopus 로고    scopus 로고
    • Functional changes in the inhibitory effect of spinal cannabinoid receptor activation in nerve injured rats
    • Chapman V. 2001. Functional changes in the inhibitory effect of spinal cannabinoid receptor activation in nerve injured rats. Neuropharmacology 41:870-877.
    • (2001) Neuropharmacology , vol.41 , pp. 870-877
    • Chapman, V.1
  • 13
    • 0036221971 scopus 로고    scopus 로고
    • CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
    • Clayton N, Marshall FH, Bountra C, O'Shaughnessy CT. 2002. CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain. Pain 96:253-260.
    • (2002) Pain , vol.96 , pp. 253-260
    • Clayton, N.1    Marshall, F.H.2    Bountra, C.3    O'Shaughnessy, C.T.4
  • 14
    • 0038545287 scopus 로고    scopus 로고
    • Increased seizure susceptibility and pro-convulsant activity of anandamide in mice lacking fatty acid amide hydrolase
    • Clement AC, Hawkins EG, Lichtman AH, Cravatt BF. 2003. Increased seizure susceptibility and pro-convulsant activity of anandamide in mice lacking fatty acid amide hydrolase. J Neurosci 23:3916-3923.
    • (2003) J Neurosci , vol.23 , pp. 3916-3923
    • Clement, A.C.1    Hawkins, E.G.2    Lichtman, A.H.3    Cravatt, B.F.4
  • 15
    • 0036157693 scopus 로고    scopus 로고
    • Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat
    • Conti S, Costa B, Colleoni M, Parolaro D, Giagnoni G. 2002. Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat. Br J Pharmacol 135:181-187.
    • (2002) Br J Pharmacol , vol.135 , pp. 181-187
    • Conti, S.1    Costa, B.2    Colleoni, M.3    Parolaro, D.4    Giagnoni, G.5
  • 16
    • 0032777297 scopus 로고    scopus 로고
    • SR141716A induces in rats a behavioral pattern opposite to that of CB1 receptor agonists
    • Costa B, Colleoni M. 1999. SR141716A induces in rats a behavioral pattern opposite to that of CB1 receptor agonists. Zhongguo Yao Li Xue Bao 20:1103-1108.
    • (1999) Zhongguo Yao Li Xue Bao , vol.20 , pp. 1103-1108
    • Costa, B.1    Colleoni, M.2
  • 17
    • 1242296234 scopus 로고    scopus 로고
    • Repeated treatment with the synthetic cannabinoid WIN 55,212-2 reduces both hyperalgesia and production of pronociceptive mediators in a rat model of neuropathic pain
    • Costa B, Colleoni M, Conti S, Trovato AE, Bianchi M, Sotgui ML, Giagnoni G. 2004. Repeated treatment with the synthetic cannabinoid WIN 55,212-2 reduces both hyperalgesia and production of pronociceptive mediators in a rat model of neuropathic pain. Br J Pharmacol 141:4-8.
    • (2004) Br J Pharmacol , vol.141 , pp. 4-8
    • Costa, B.1    Colleoni, M.2    Conti, S.3    Trovato, A.E.4    Bianchi, M.5    Sotgui, M.L.6    Giagnoni, G.7
  • 19
  • 20
    • 0037207093 scopus 로고    scopus 로고
    • The enzymatic inactivation of the fatty acid amide class of signaling lipids
    • Cravatt BF, Lichtman AH. 2002. The enzymatic inactivation of the fatty acid amide class of signaling lipids. Chem Phys Lipids 121:135-148.
    • (2002) Chem Phys Lipids , vol.121 , pp. 135-148
    • Cravatt, B.F.1    Lichtman, A.H.2
  • 23
    • 0032784084 scopus 로고    scopus 로고
    • Cannabimimetic fatty acid derivatives: The anandamide family and other endocannabinoids
    • Di Marzo V, Bisogno T, De Petrocellis L, Melck D, Martin BR. 1999. Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids. Curr Med Chem 6:721-744.
    • (1999) Curr Med Chem , vol.6 , pp. 721-744
    • Di Marzo, V.1    Bisogno, T.2    De Petrocellis, L.3    Melck, D.4    Martin, B.R.5
  • 26
    • 0037207088 scopus 로고    scopus 로고
    • A role for monoacylglyceride lipase in 2-arachidonoylglycerol inactivation
    • Dinh TP, Freund TF, Piomelli D. 2002. A role for monoacylglyceride lipase in 2-arachidonoylglycerol inactivation. Chem Phys Lipids 2002:149-158.
    • (2002) Chem Phys Lipids , vol.2002 , pp. 149-158
    • Dinh, T.P.1    Freund, T.F.2    Piomelli, D.3
  • 27
    • 0036844373 scopus 로고    scopus 로고
    • "Knock-down" of spinal CB1 receptors produces abnormal pain and elevates spinal dynorphin content in mice
    • Dogrul A, Gardell LR, Ma S, Ossipov MH, Porreca F, Lai J. 2002. "Knock-down" of spinal CB1 receptors produces abnormal pain and elevates spinal dynorphin content in mice. Pain 100:203-209.
    • (2002) Pain , vol.100 , pp. 203-209
    • Dogrul, A.1    Gardell, L.R.2    Ma, S.3    Ossipov, M.H.4    Porreca, F.5    Lai, J.6
  • 28
    • 0034119759 scopus 로고    scopus 로고
    • Activation of spinal cannabinoid I receptors inhibits C-fibre driven hyperexcitable neuronal responses and increases [35]SGTPgammaS bindiing in the dorsal horn of the spinal cord of noninflamed and inflamed rats
    • Drew LJ, Harris J, Millns PJ, Kendall DA, Chapman V. 2000. Activation of spinal cannabinoid I receptors inhibits C-fibre driven hyperexcitable neuronal responses and increases [35]SGTPgammaS bindiing in the dorsal horn of the spinal cord of noninflamed and inflamed rats. Eur J Neurosci 12:2079-2086.
    • (2000) Eur J Neurosci , vol.12 , pp. 2079-2086
    • Drew, L.J.1    Harris, J.2    Millns, P.J.3    Kendall, D.A.4    Chapman, V.5
  • 29
    • 0032494704 scopus 로고    scopus 로고
    • A new perspective on cannabinoid signalling: Complimentary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain
    • Egertova M, Giang DK, Cravatt BF, Elphick MR. 1998. A new perspective on cannabinoid signalling: Complimentary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain. Proc R Soc Lond B 265:2081-2085.
    • (1998) Proc R Soc Lond B , vol.265 , pp. 2081-2085
    • Egertova, M.1    Giang, D.K.2    Cravatt, B.F.3    Elphick, M.R.4
  • 31
    • 0035059241 scopus 로고    scopus 로고
    • The role of central and peripheral cannabinoid 1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain
    • Fox A, Kesingland A, Gentry C, McNair K, Patel S, Urban L, James I. 2001. The role of central and peripheral cannabinoid 1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain. Pain 92:91-100.
    • (2001) Pain , vol.92 , pp. 91-100
    • Fox, A.1    Kesingland, A.2    Gentry, C.3    McNair, K.4    Patel, S.5    Urban, L.6    James, I.7
  • 33
    • 0034978249 scopus 로고    scopus 로고
    • Mechanisms of endocannabinoid inactivation: Biochemistry and pharmacology
    • Giuffrida A, Beltramo M, Piomelli D. 2001. Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology. J Pharmacol Exp Ther 298:7-14.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 7-14
    • Giuffrida, A.1    Beltramo, M.2    Piomelli, D.3
  • 35
    • 0032559369 scopus 로고    scopus 로고
    • Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand
    • Goparaju SK, Ueda N, Yamaguchi H, Yamamoto S. 1998. Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand. FEES Lett 422:69-73.
    • (1998) FEES Lett , vol.422 , pp. 69-73
    • Goparaju, S.K.1    Ueda, N.2    Yamaguchi, H.3    Yamamoto, S.4
  • 38
    • 0342762087 scopus 로고    scopus 로고
    • The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuorpathic pain
    • Herzberg U, Eliav E, Bennett GJ, Kopin IJ. 1997. The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuorpathic pain. Neurosci Lett 221:157-160.
    • (1997) Neurosci Lett , vol.221 , pp. 157-160
    • Herzberg, U.1    Eliav, E.2    Bennett, G.J.3    Kopin, I.J.4
  • 39
    • 0033666960 scopus 로고    scopus 로고
    • The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes
    • Hillard CJ, Jarrahian A. 2000. The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes. Chem Phys Lipids 108:123-134.
    • (2000) Chem Phys Lipids , vol.108 , pp. 123-134
    • Hillard, C.J.1    Jarrahian, A.2
  • 40
    • 0037207078 scopus 로고    scopus 로고
    • Spinal and peripheral mechanisms of cannabinoid antinociception: Behavioral, neurophysiological, and neuroanatomical perspectives
    • Hohmann AG. 2002. Spinal and peripheral mechanisms of cannabinoid antinociception: behavioral, neurophysiological, and neuroanatomical perspectives. Chem Phys Lipids 31:173-190.
    • (2002) Chem Phys Lipids , vol.31 , pp. 173-190
    • Hohmann, A.G.1
  • 41
    • 1642498189 scopus 로고    scopus 로고
    • Selective activation of cannabinoid CB2 receptors suppresses hyperalgesia evoked by intradermal capsaicin
    • Hohmann AG, Farthing JN, Zvonok AM, Makriyannis A. 2004. Selective activation of cannabinoid CB2 receptors suppresses hyperalgesia evoked by intradermal capsaicin. J Pharmacol Exp Ther 308:446-453.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 446-453
    • Hohmann, A.G.1    Farthing, J.N.2    Zvonok, A.M.3    Makriyannis, A.4
  • 42
    • 0029070520 scopus 로고
    • Inhibition of noxious stimulus-evoked activity of spinal cord dorsal horn neurons by the cannabinoid WIN 55,212-2
    • Hohmann AG, Martin WJ, Tsou K, Walker JM. 1995. Inhibition of noxious stimulus-evoked activity of spinal cord dorsal horn neurons by the cannabinoid WIN 55,212-2. Life Sci 56:2111-2118.
    • (1995) Life Sci , vol.56 , pp. 2111-2118
    • Hohmann, A.G.1    Martin, W.J.2    Tsou, K.3    Walker, J.M.4
  • 43
    • 0032484245 scopus 로고    scopus 로고
    • Cannabinoid modulaton of wide dynamic range neurons in the lumbar dorsal horn of the rat by spinally administered WIN55.212-2
    • Hohmann AG, Tsou K, Walker JM. 1998. Cannabinoid modulaton of wide dynamic range neurons in the lumbar dorsal horn of the rat by spinally administered WIN55.212-2. Neurosci Lett 257:119-122.
    • (1998) Neurosci Lett , vol.257 , pp. 119-122
    • Hohmann, A.G.1    Tsou, K.2    Walker, J.M.3
  • 45
    • 0035142746 scopus 로고    scopus 로고
    • In vitro and in vivo pharmacological characterization of JTE-907, a novel selective ligand for the cannabinoid CB2 receptor
    • Iwamura H, Suzuki H, Ueda Y, Kaya T, Inaba T. 2001. In vitro and in vivo pharmacological characterization of JTE-907, a novel selective ligand for the cannabinoid CB2 receptor. J Pharmacol Exp Ther 296:420-425.
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 420-425
    • Iwamura, H.1    Suzuki, H.2    Ueda, Y.3    Kaya, T.4    Inaba, T.5
  • 46
    • 0031776783 scopus 로고    scopus 로고
    • The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain
    • Jaggar SI, Hasnie FS, Sellaturay S, Rice AS. 1998. The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. Pain 76:189-199.
    • (1998) Pain , vol.76 , pp. 189-199
    • Jaggar, S.I.1    Hasnie, F.S.2    Sellaturay, S.3    Rice, A.S.4
  • 48
    • 0034747415 scopus 로고    scopus 로고
    • Selective cannabinoid CB1 receptor activation inhibits spinal nociceptive transmission in vivo
    • Kelly S, Chapman V. 2001. Selective cannabinoid CB1 receptor activation inhibits spinal nociceptive transmission in vivo. J Neurophys 86:3061-3064.
    • (2001) J Neurophys , vol.86 , pp. 3061-3064
    • Kelly, S.1    Chapman, V.2
  • 51
    • 0038361307 scopus 로고    scopus 로고
    • Discovering potent and selective inhibitors of enzymes in complex proteomes
    • Leung D, Hardouin C, Boger DL, Cravatt BF. 2003. Discovering potent and selective inhibitors of enzymes in complex proteomes. Nat Biotechnol 21:687-691.
    • (2003) Nat Biotechnol , vol.21 , pp. 687-691
    • Leung, D.1    Hardouin, C.2    Boger, D.L.3    Cravatt, B.F.4
  • 52
    • 0030087731 scopus 로고    scopus 로고
    • Investigation of brain sites mediating cannabinoid-induced antinociception in rats: Evidence supporting periaqueductal gray involvement
    • Lichtman AH, Cook SA, Martin BR. 1996. Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement. J Pharmacol Exp Ther 276:585-593.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 585-593
    • Lichtman, A.H.1    Cook, S.A.2    Martin, B.R.3
  • 53
    • 0036089489 scopus 로고    scopus 로고
    • Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo
    • Lichtman AH, Hawkins EG, Griffin G, Cravatt BF. 2002. Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo. J Pharmacol Exp Ther 302:73-79.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 73-79
    • Lichtman, A.H.1    Hawkins, E.G.2    Griffin, G.3    Cravatt, B.F.4
  • 54
    • 4644354869 scopus 로고    scopus 로고
    • Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: Evidence for an unprecedented combination of potency and selectivity
    • to appear
    • Lichtman AH, Leung D, Shelton C, Saghatelian A, Hardouin C, Boger DL, Cravatt BF. 2004a. Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity. J Pharmacol Exp Ther, to appear.
    • (2004) J Pharmacol Exp Ther
    • Lichtman, A.H.1    Leung, D.2    Shelton, C.3    Saghatelian, A.4    Hardouin, C.5    Boger, D.L.6    Cravatt, B.F.7
  • 55
    • 0025943354 scopus 로고
    • Spinal and supraspinal mechanisms of cannabinoid-induced antinociception
    • Lichtman AH, Martin BR. 1991. Spinal and supraspinal mechanisms of cannabinoid-induced antinociception. J Pharmacol Exp Ther 258:517-523.
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 517-523
    • Lichtman, A.H.1    Martin, B.R.2
  • 56
    • 4644355300 scopus 로고    scopus 로고
    • The selective cannabinoid antagonist, SR141716A, blocks cannabinoid-induced antinociception following intraventricular administration in rats
    • Lichtman AH, Martin BR. 1997. The selective cannabinoid antagonist, SR141716A, blocks cannabinoid-induced antinociception following intraventricular administration in rats. Brain Res 629:300-304.
    • (1997) Brain Res , vol.629 , pp. 300-304
    • Lichtman, A.H.1    Martin, B.R.2
  • 57
    • 2442510225 scopus 로고    scopus 로고
    • Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia
    • Lichtman AH, Shelton CC, Advani T, Cravatt BF. 2004b. Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. Pain 109:319-327.
    • (2004) Pain , vol.109 , pp. 319-327
    • Lichtman, A.H.1    Shelton, C.C.2    Advani, T.3    Cravatt, B.F.4
  • 58
    • 0026675157 scopus 로고
    • The antinociceptive effects of intrathecally administered cannabinoids are influenced by lipophilicity
    • Lichtman AH, Smith PB, Martin BR. 1992. The antinociceptive effects of intrathecally administered cannabinoids are influenced by lipophilicity. Pain 51:19-26.
    • (1992) Pain , vol.51 , pp. 19-26
    • Lichtman, A.H.1    Smith, P.B.2    Martin, B.R.3
  • 59
    • 0141738711 scopus 로고    scopus 로고
    • Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behavior in rats
    • Lim G, Sung B, Ji RR, Mao J. 2003. Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behavior in rats. Pain 105:275-283.
    • (2003) Pain , vol.105 , pp. 275-283
    • Lim, G.1    Sung, B.2    Ji, R.R.3    Mao, J.4
  • 64
    • 0032459476 scopus 로고    scopus 로고
    • Cannabinoid transmission and pain perception
    • Martin BR, Lichtman AH. 1998. Cannabinoid transmission and pain perception. Neurobiol Dis 5:447-461.
    • (1998) Neurobiol Dis , vol.5 , pp. 447-461
    • Martin, B.R.1    Lichtman, A.H.2
  • 65
    • 0029816889 scopus 로고    scopus 로고
    • Suppression of noxious stimulus-evoked activity in the ventral posterolateral nucleus of the thalamus by a cannabinoid agonist: Correlation between electrophysiological and antinociceptiv effects
    • Martin WJ, Hohmann AG, Walker JM. 1996. Suppression of noxious stimulus-evoked activity in the ventral posterolateral nucleus of the thalamus by a cannabinoid agonist: correlation between electrophysiological and antinociceptiv effects. J Neurosci 16:6601-6611.
    • (1996) J Neurosci , vol.16 , pp. 6601-6611
    • Martin, W.J.1    Hohmann, A.G.2    Walker, J.M.3
  • 66
    • 0027444581 scopus 로고
    • Antinociceptive actions of cannabinoids following intraventricular administration in rats
    • Martin WJ, Lai NK, Patrick SL, Tsou K, Walker JM. 1993. Antinociceptive actions of cannabinoids following intraventricular administration in rats. Brain Res 629:300-304.
    • (1993) Brain Res , vol.629 , pp. 300-304
    • Martin, W.J.1    Lai, N.K.2    Patrick, S.L.3    Tsou, K.4    Walker, J.M.5
  • 67
    • 0033027735 scopus 로고    scopus 로고
    • Spinal cannabinoids are anti-allodynic in rats with persistent inflammation
    • Martin WJ, Loo CM, Basbaum AI. 1999. Spinal cannabinoids are anti-allodynic in rats with persistent inflammation. Pain 82:199-205.
    • (1999) Pain , vol.82 , pp. 199-205
    • Martin, W.J.1    Loo, C.M.2    Basbaum, A.I.3
  • 68
    • 0029036140 scopus 로고
    • An examination of central sites of action of cannabinoid-induced antinociception in the rat
    • Martin WJ, Patrick SL, Coffin PO, Tsou K, Walker JM. 1995. An examination of central sites of action of cannabinoid-induced antinociception in the rat. Life Sci 56:2103-2109.
    • (1995) Life Sci , vol.56 , pp. 2103-2109
    • Martin, W.J.1    Patrick, S.L.2    Coffin, P.O.3    Tsou, K.4    Walker, J.M.5
  • 70
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI. 1990. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346:561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 76
    • 0035838275 scopus 로고    scopus 로고
    • CB1 receptor mediated analgesia from the nucleus reticularis gigantocellularis pars alpha is activated in an anmial model of neuropathic pain
    • Monhemius R, Azami J, Green DL, Roberts MH. 2001. CB1 receptor mediated analgesia from the nucleus reticularis gigantocellularis pars alpha is activated in an anmial model of neuropathic pain. Brain Res 908:67-74.
    • (2001) Brain Res , vol.908 , pp. 67-74
    • Monhemius, R.1    Azami, J.2    Green, D.L.3    Roberts, M.H.4
  • 77
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S, Thomas KL, Abu-Shaar M. 1993. Molecular characterization of a peripheral receptor for cannabinoids. Nature 365:61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 78
    • 0038521050 scopus 로고    scopus 로고
    • Selective activation of cannabinoid CB2 receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation
    • Nackley AG, Makriyannis A, Hohmann AG. 2003. Selective activation of cannabinoid CB2 receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation. Neuroscience 119:747-757.
    • (2003) Neuroscience , vol.119 , pp. 747-757
    • Nackley, A.G.1    Makriyannis, A.2    Hohmann, A.G.3
  • 80
    • 1242294480 scopus 로고    scopus 로고
    • Molecular characterization of a phospholipase D generating anandamide and its congeners
    • Okamoto Y, Morishita J, Tsuboi K, Tonai T, Ueda N. 2004. Molecular characterization of a phospholipase D generating anandamide and its congeners. J Biol Chem 279:5298-5305.
    • (2004) J Biol Chem , vol.279 , pp. 5298-5305
    • Okamoto, Y.1    Morishita, J.2    Tsuboi, K.3    Tonai, T.4    Ueda, N.5
  • 81
    • 0035235117 scopus 로고    scopus 로고
    • Proteins regulating the biosynthesis and inactivation of neuromodulatory fatty acid amides
    • Patricelli, MP, Cravatt, BF. 2001. Proteins regulating the biosynthesis and inactivation of neuromodulatory fatty acid amides. Vitam Horm 62:95-131.
    • (2001) Vitam Horm , vol.62 , pp. 95-131
    • Patricelli, M.P.1    Cravatt, B.F.2
  • 82
    • 0035150352 scopus 로고    scopus 로고
    • Cannabinoid receptors and pain
    • Pertwee RG. 2001. Cannabinoid receptors and pain. Prog Neurobiol 63:569-611.
    • (2001) Prog Neurobiol , vol.63 , pp. 569-611
    • Pertwee, R.G.1
  • 86
    • 0031974179 scopus 로고    scopus 로고
    • Hypoactivity of the spinal cannabinoid system results in NMDA-dependent hyperalgesia
    • Richardson JD, Aanonsen L, Hargreaves K. 1998a. Hypoactivity of the spinal cannabinoid system results in NMDA-dependent hyperalgesia. J Neurosci 18:451-457.
    • (1998) J Neurosci , vol.18 , pp. 451-457
    • Richardson, J.D.1    Aanonsen, L.2    Hargreaves, K.3
  • 87
    • 0031779305 scopus 로고    scopus 로고
    • Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors
    • Richardson JD, Kilo S, Hargreaves KM. 1998b. Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. Pain 75:111-119.
    • (1998) Pain , vol.75 , pp. 111-119
    • Richardson, J.D.1    Kilo, S.2    Hargreaves, K.M.3
  • 88
    • 0028129936 scopus 로고
    • SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
    • Rinaldi-Carmona M, et al. 1994. SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEES Lett 350:240-244.
    • (1994) FEES Lett , vol.350 , pp. 240-244
    • Rinaldi-Carmona, M.1
  • 90
    • 0032777310 scopus 로고    scopus 로고
    • CB1 receptor localization in rat spinal cord and roots, dorsal root ganglion, and peripheral nerve
    • Sanudo-Pena MC, Strangman NM, Mackie K, Walker JM, Tsou K. 1999. CB1 receptor localization in rat spinal cord and roots, dorsal root ganglion, and peripheral nerve. Zhongguo Yao Li Xue Bao 20:1115-1120.
    • (1999) Zhongguo Yao Li Xue Bao , vol.20 , pp. 1115-1120
    • Sanudo-Pena, M.C.1    Strangman, N.M.2    Mackie, K.3    Walker, J.M.4    Tsou, K.5
  • 92
    • 0035831179 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor upregulation in a rat model of chronic neuropathic pain
    • Siegling A, Hofmann HA, Denzer D, Mauler F, Vry D. 2001. Cannabinoid CB1 receptor upregulation in a rat model of chronic neuropathic pain. Eur J Pharmacol 415:R5-R7.
    • (2001) Eur J Pharmacol , vol.415
    • Siegling, A.1    Hofmann, H.A.2    Denzer, D.3    Mauler, F.4    Vry, D.5
  • 93
    • 4644373803 scopus 로고    scopus 로고
    • 2002. Bisarylimidazolyl fatty acid amide hydrolase inhibitors. Patent W0 02/087569
    • Sit S-Y, Xie K. 2002. Bisarylimidazolyl fatty acid amide hydrolase inhibitors. Patent W0 02/087569.
    • Sit, S.-Y.1    Xie, K.2
  • 94
    • 4644321841 scopus 로고    scopus 로고
    • 2003. (Oxime)carbamoyl fatty acid amide hydrolase inhibitors. Patent Application US 2003/0195226 A1
    • Sit S-Y, Xie K. 2003. (Oxime)carbamoyl fatty acid amide hydrolase inhibitors. Patent Application US 2003/0195226 A1.
    • Sit, S.-Y.1    Xie, K.2
  • 95
    • 0032056333 scopus 로고    scopus 로고
    • Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats
    • Smith FL, Fujimori K, Lowe J, Welch SP. 1998. Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. Pharmacol Biochem Behav 60:183-191.
    • (1998) Pharmacol Biochem Behav , vol.60 , pp. 183-191
    • Smith, F.L.1    Fujimori, K.2    Lowe, J.3    Welch, S.P.4
  • 96
    • 0025943354 scopus 로고
    • Spinal and supraspinal mechanisms of cannabinoid-induced antinociception
    • Smith PB, Martin BR. 1992. Spinal and supraspinal mechanisms of cannabinoid-induced antinociception. J Pharmacol Exp Ther 258:517-523.
    • (1992) J Pharmacol Exp Ther , vol.258 , pp. 517-523
    • Smith, P.B.1    Martin, B.R.2
  • 97
    • 0030870722 scopus 로고    scopus 로고
    • A second endogenous cannabinoid that modulates long term potentiation
    • Stella N, Schweitzer P, Piomelli D. 1997. A second endogenous cannabinoid that modulates long term potentiation. Nature 388:773-778.
    • (1997) Nature , vol.388 , pp. 773-778
    • Stella, N.1    Schweitzer, P.2    Piomelli, D.3
  • 98
    • 0032495194 scopus 로고    scopus 로고
    • Evidence for a role for endogenous cannabinoids in the modulation of acute and tonic pain sensitivity
    • Strangman NM, Patrick SL, Hohmann AG, Tsou K, Walker JM. 1998. Evidence for a role for endogenous cannabinoids in the modulation of acute and tonic pain sensitivity. Brain Res 813:323-328.
    • (1998) Brain Res , vol.813 , pp. 323-328
    • Strangman, N.M.1    Patrick, S.L.2    Hohmann, A.G.3    Tsou, K.4    Walker, J.M.5
  • 99
    • 0032778413 scopus 로고    scopus 로고
    • The cannabinoid WIN 55,212-2 inhibits the activity dependent facilitation of spinal nociceptive responses
    • Strangman NM, Walker JM. 1999. The cannabinoid WIN 55,212-2 inhibits the activity dependent facilitation of spinal nociceptive responses. J Neurophys 81:472-477.
    • (1999) J Neurophys , vol.81 , pp. 472-477
    • Strangman, N.M.1    Walker, J.M.2
  • 100
    • 0029798721 scopus 로고    scopus 로고
    • Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonylethanolamine, an endogenous cannabinoid receptor ligand in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine
    • Sugiura T, Kondo S, Sukagawa A, Tonegawa T, Nakane S, Yamshita A, Waku K. 1996. Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonylethanolamine, an endogenous cannabinoid receptor ligand in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine. Eur J Biochem 240:53-62.
    • (1996) Eur J Biochem , vol.240 , pp. 53-62
    • Sugiura, T.1    Kondo, S.2    Sukagawa, A.3    Tonegawa, T.4    Nakane, S.5    Yamshita, A.6    Waku, K.7
  • 101
    • 0031929438 scopus 로고    scopus 로고
    • Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
    • Tsou K, Brown S, Sanudo-Pena MC, Mackie K, Walker JM, 1998. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience 83:393-411.
    • (1998) Neuroscience , vol.83 , pp. 393-411
    • Tsou, K.1    Brown, S.2    Sanudo-Pena, M.C.3    Mackie, K.4    Walker, J.M.5
  • 102
    • 0034095022 scopus 로고    scopus 로고
    • Reduction of stress-induced analgesia but not exogenous opioid effects in mice lacking CB1 receptors
    • Valverde O, Ledent C, Beslot F, Parmentier M, Roques BP, 2000. Reduction of stress-induced analgesia but not exogenous opioid effects in mice lacking CB1 receptors. Eur J Neurosci 12:533-539.
    • (2000) Eur J Neurosci , vol.12 , pp. 533-539
    • Valverde, O.1    Ledent, C.2    Beslot, F.3    Parmentier, M.4    Roques, B.P.5
  • 103
    • 0036015096 scopus 로고    scopus 로고
    • Evaluation of CB1 receptor knockout mice in the Morris water maze
    • Varvel SA, Lichtman AH. 2002. Evaluation of CB1 receptor knockout mice in the Morris water maze. J Pharmacol Exp Ther 301:915-924.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 915-924
    • Varvel, S.A.1    Lichtman, A.H.2
  • 106
    • 0019605642 scopus 로고
    • The antinociceptive effects of intrathecally-administered levonantradol and deacetyllevonantradol in the rat
    • Yaksh TL. 1981. The antinociceptive effects of intrathecally-administered levonantradol and deacetyllevonantradol in the rat. J Clin Pharmacol 21:3348-3408.
    • (1981) J Clin Pharmacol , vol.21 , pp. 3348-3408
    • Yaksh, T.L.1
  • 107
    • 0038684167 scopus 로고    scopus 로고
    • Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models
    • Zhang J, Hoffet C, Vu HK, Groblewski T, Ahmad S, O'Donnell D. 2003. Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models. Eur J Neurosci 17:2750-2754.
    • (2003) Eur J Neurosci , vol.17 , pp. 2750-2754
    • Zhang, J.1    Hoffet, C.2    Vu, H.K.3    Groblewski, T.4    Ahmad, S.5    O'Donnell, D.6
  • 108
    • 0033545866 scopus 로고    scopus 로고
    • Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
    • Zimmer A, Zimmer AM, Hohmann AG, Herkenham M, Bonner TI. 1999. Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc Natl Acad Sci 96:5780-5785.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 5780-5785
    • Zimmer, A.1    Zimmer, A.M.2    Hohmann, A.G.3    Herkenham, M.4    Bonner, T.I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.