-
1
-
-
27644578059
-
Cannabinoid mechanisms of pain suppression
-
Walker, J.M. & Hohmann, A.G. Cannabinoid mechanisms of pain suppression. Handb. Exp. Pharmacol. 168, 509-554 (2005).
-
(2005)
Handb. Exp. Pharmacol
, vol.168
, pp. 509-554
-
-
Walker, J.M.1
Hohmann, A.G.2
-
2
-
-
33748703859
-
The endocannabinoid system as an emerging target of pharmacotherapy
-
Pacher, P., Batkai, S. & Kunos, G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol. Rev. 58, 389-462 (2006).
-
(2006)
Pharmacol. Rev
, vol.58
, pp. 389-462
-
-
Pacher, P.1
Batkai, S.2
Kunos, G.3
-
3
-
-
0037661996
-
Role of endogenous cannabinoids in synaptic signaling
-
Freund, T.F., Katona, I. & Piomelli, D. Role of endogenous cannabinoids in synaptic signaling. Physiol. Rev. 83, 1017-1066 (2003).
-
(2003)
Physiol. Rev
, vol.83
, pp. 1017-1066
-
-
Freund, T.F.1
Katona, I.2
Piomelli, D.3
-
4
-
-
21344432777
-
The endocannabinoid system: A drug discovery perspective
-
Piomelli, D. The endocannabinoid system: a drug discovery perspective. Curr. Opin. Investig. Drugs 6, 672-679 (2005).
-
(2005)
Curr. Opin. Investig. Drugs
, vol.6
, pp. 672-679
-
-
Piomelli, D.1
-
5
-
-
33746621595
-
The cannabinoid WIN55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurin
-
Patwardhan, A.M. et al. The cannabinoid WIN55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurin. Proc. Natl. Acad. Sci. USA 103, 11393-11398 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11393-11398
-
-
Patwardhan, A.M.1
-
6
-
-
1842534335
-
+ channels by membrane lipids
-
+ channels by membrane lipids. Science 304, 265-270 (2004).
-
(2004)
Science
, vol.304
, pp. 265-270
-
-
Oliver, D.1
-
7
-
-
0033555839
-
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
-
Ledent, C. et al. Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 283, 401-404 (1999).
-
(1999)
Science
, vol.283
, pp. 401-404
-
-
Ledent, C.1
-
8
-
-
0033545866
-
Increased mortality, hypoactivity and hypoalgesia in cannabinoid CB1 receptor knockout mice
-
Zimmer, A., Zimmer, A.M., Hohmann, A.G., Herkenham, M. & Bonner, T.I. Increased mortality, hypoactivity and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc. Natl. Acad. Sci. USA 96, 5780-5785 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5780-5785
-
-
Zimmer, A.1
Zimmer, A.M.2
Hohmann, A.G.3
Herkenham, M.4
Bonner, T.I.5
-
9
-
-
33646062552
-
CB2 cannabinoid receptor mediation of antinociception
-
Ibrahim, M.M. et al. CB2 cannabinoid receptor mediation of antinociception. Pain 122, 36-42 (2006).
-
(2006)
Pain
, vol.122
, pp. 36-42
-
-
Ibrahim, M.M.1
-
10
-
-
0029155706
-
Inducible gene targeting in mice
-
Kuhn, R., Schwenk, F., Aguet, M. & Rajewsky, K. Inducible gene targeting in mice. Science 269, 1427-1429 (1995).
-
(1995)
Science
, vol.269
, pp. 1427-1429
-
-
Kuhn, R.1
Schwenk, F.2
Aguet, M.3
Rajewsky, K.4
-
11
-
-
0141865717
-
CB1 cannabinoid receptors and on-demand defense against excitotoxicity
-
Marsicano, G. et al. CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science 302, 84-88 (2003).
-
(2003)
Science
, vol.302
, pp. 84-88
-
-
Marsicano, G.1
-
12
-
-
1942423228
-
Conditional gene deletion in primary nociceptive neurons of trigeminal ganglia and dorsal root ganglia
-
Agarwal, N., Offermanns, S. & Kuner, R. Conditional gene deletion in primary nociceptive neurons of trigeminal ganglia and dorsal root ganglia. Genesis 38, 122-129 (2004).
-
(2004)
Genesis
, vol.38
, pp. 122-129
-
-
Agarwal, N.1
Offermanns, S.2
Kuner, R.3
-
13
-
-
0036682222
-
The endogenous cannabinoid system controls extinction of aversive memories
-
Marsicano, G. et al. The endogenous cannabinoid system controls extinction of aversive memories. Nature 418, 530-534 (2002).
-
(2002)
Nature
, vol.418
, pp. 530-534
-
-
Marsicano, G.1
-
14
-
-
0033785482
-
Changes in the cannabinoid receptor binding, G protein coupling and cyclic AMP cascade in the CNS of rats tolerant to and dependent on the synthetic cannabinoid compound CP55,940
-
Rubino, T., Vigano, D., Massi, P. & Parolaro, D. Changes in the cannabinoid receptor binding, G protein coupling and cyclic AMP cascade in the CNS of rats tolerant to and dependent on the synthetic cannabinoid compound CP55,940. J. Neurochem. 75, 2080-2086 (2000).
-
(2000)
J. Neurochem
, vol.75
, pp. 2080-2086
-
-
Rubino, T.1
Vigano, D.2
Massi, P.3
Parolaro, D.4
-
15
-
-
0033490464
-
Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity
-
Ji, R.R., Baba, H., Brenner, G.J. & Woolf, C.J. Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat. Neurosci. 2, 1114-1119 (1999).
-
(1999)
Nat. Neurosci
, vol.2
, pp. 1114-1119
-
-
Ji, R.R.1
Baba, H.2
Brenner, G.J.3
Woolf, C.J.4
-
16
-
-
8844234340
-
The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory pain
-
Hartmann, B. et al. The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory pain. Neuron 44, 637-650 (2004).
-
(2004)
Neuron
, vol.44
, pp. 637-650
-
-
Hartmann, B.1
-
17
-
-
0023221062
-
Experimental acute pancreatitis. In vitro magnetic resonance characteristics
-
Tsay, D.G. et al. Experimental acute pancreatitis. In vitro magnetic resonance characteristics. Invest. Radiol. 22, 556-561 (1987).
-
(1987)
Invest. Radiol
, vol.22
, pp. 556-561
-
-
Tsay, D.G.1
-
18
-
-
0032588211
-
i in the ATP-induced heat sensitization process of rat nociceptive neurons
-
i in the ATP-induced heat sensitization process of rat nociceptive neurons. J. Neurophysiol. 81, 2612-2619 (1999).
-
(1999)
J. Neurophysiol
, vol.81
, pp. 2612-2619
-
-
Kress, M.1
Guenther, S.2
-
19
-
-
0141832155
-
Topical cannabinoid antinociception: Synergy with spinal sites
-
Dogrul, A. et al. Topical cannabinoid antinociception: synergy with spinal sites. Pain 105, 11-16 (2003).
-
(2003)
Pain
, vol.105
, pp. 11-16
-
-
Dogrul, A.1
-
20
-
-
0015445325
-
The ring test: A quantitative method for assessing the 'cataleptic' effect of cannabis in mice
-
Pertwee, R.G. The ring test: a quantitative method for assessing the 'cataleptic' effect of cannabis in mice. Br. J. Pharmacol. 46, 753-763 (1972).
-
(1972)
Br. J. Pharmacol
, vol.46
, pp. 753-763
-
-
Pertwee, R.G.1
-
21
-
-
0031779305
-
Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors
-
Richardson, J.D., Kilo, S. & Hargreaves, K.M. Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. Pain 75, 111-119 (1998).
-
(1998)
Pain
, vol.75
, pp. 111-119
-
-
Richardson, J.D.1
Kilo, S.2
Hargreaves, K.M.3
-
22
-
-
27644549880
-
A cannabinoid agonist, WIN55,212-2, reduces neuropathic nociception induced by paclitaxel in rats
-
Pascual, D., Goicoechea, C., Suardiaz, M. & Martin, M.I. A cannabinoid agonist, WIN55,212-2, reduces neuropathic nociception induced by paclitaxel in rats. Pain 118, 23-34 (2005).
-
(2005)
Pain
, vol.118
, pp. 23-34
-
-
Pascual, D.1
Goicoechea, C.2
Suardiaz, M.3
Martin, M.I.4
-
23
-
-
0035059241
-
The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain
-
Fox, A. et al. The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain. Pain 92, 91-100 (2001).
-
(2001)
Pain
, vol.92
, pp. 91-100
-
-
Fox, A.1
-
24
-
-
3242659177
-
Transdermal delivery of the synthetic cannabinoid WIN55,212-2: In vitro/in vivo correlation
-
Valiveti, S., Hammell, D.C., Earles, D.C. & Stinchcomb, A.L. Transdermal delivery of the synthetic cannabinoid WIN55,212-2: in vitro/in vivo correlation. Pharm Res. 21, 1137-1145 (2004).
-
(2004)
Pharm Res
, vol.21
, pp. 1137-1145
-
-
Valiveti, S.1
Hammell, D.C.2
Earles, D.C.3
Stinchcomb, A.L.4
-
25
-
-
0034951162
-
The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain
-
Bridges, D., Ahmad, K. & Rice, A.S. The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain. Br. J. Pharmacol. 133, 586-594 (2001).
-
(2001)
Br. J. Pharmacol
, vol.133
, pp. 586-594
-
-
Bridges, D.1
Ahmad, K.2
Rice, A.S.3
-
26
-
-
0034255439
-
Spared nerve injury: An animal model of persistent peripheral neuropathic pain
-
Decosterd, I. & Woolf, C.J. Spared nerve injury: an animal model of persistent peripheral neuropathic pain. Pain 87, 149-158 (2000).
-
(2000)
Pain
, vol.87
, pp. 149-158
-
-
Decosterd, I.1
Woolf, C.J.2
-
27
-
-
0032940633
-
Localization of central cannabinoid CB1 receptor messenger RNA in neuronal subpopulations of rat dorsal root ganglia: A double-label in situ hybridization study
-
Hohmann, A.G. & Herkenham, M. Localization of central cannabinoid CB1 receptor messenger RNA in neuronal subpopulations of rat dorsal root ganglia: a double-label in situ hybridization study. Neuroscience 90, 923-931 (1999).
-
(1999)
Neuroscience
, vol.90
, pp. 923-931
-
-
Hohmann, A.G.1
Herkenham, M.2
-
28
-
-
0038182182
-
Localisation of cannabinoid receptor 1 in rat dorsal root ganglion using in situ hybridisation and immunohistochemistry
-
Bridges, D. et al. Localisation of cannabinoid receptor 1 in rat dorsal root ganglion using in situ hybridisation and immunohistochemistry. Neuroscience 119, 803-812 (2003).
-
(2003)
Neuroscience
, vol.119
, pp. 803-812
-
-
Bridges, D.1
-
29
-
-
33748804164
-
Co-expression of the voltage-gated potassium channel Kv1.4 with transient receptor potential channels (TRPV1 and TRPV2) and the cannabinoid receptor CB1 in rat dorsal root ganglion neurons
-
Binzen, U. et al. Co-expression of the voltage-gated potassium channel Kv1.4 with transient receptor potential channels (TRPV1 and TRPV2) and the cannabinoid receptor CB1 in rat dorsal root ganglion neurons. Neuroscience 142, 527-539 (2006).
-
(2006)
Neuroscience
, vol.142
, pp. 527-539
-
-
Binzen, U.1
-
30
-
-
33751244807
-
Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain
-
Mitrirattanakul, S. et al. Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain. Pain 126, 102-114 (2006).
-
(2006)
Pain
, vol.126
, pp. 102-114
-
-
Mitrirattanakul, S.1
-
31
-
-
0028931849
-
An amino-terminal variant of the central cannabinoid receptor resulting from alternative splicing
-
Shire, D. et al. An amino-terminal variant of the central cannabinoid receptor resulting from alternative splicing. J. Biol. Chem. 270, 3726-3731 (1995).
-
(1995)
J. Biol. Chem
, vol.270
, pp. 3726-3731
-
-
Shire, D.1
-
33
-
-
0027444581
-
Antinociceptive actions of cannabinoids following intraventricular administration in rats
-
Martin, W.J., Lai, N.K., Patrick, S.L., Tsou, K. & Walker, J.M. Antinociceptive actions of cannabinoids following intraventricular administration in rats. Brain Res. 629, 300-304 (1993).
-
(1993)
Brain Res
, vol.629
, pp. 300-304
-
-
Martin, W.J.1
Lai, N.K.2
Patrick, S.L.3
Tsou, K.4
Walker, J.M.5
-
34
-
-
7744233610
-
Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling
-
Azad, S.C. et al. Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling. J. Neurosci. 24, 9953-9961 (2004).
-
(2004)
J. Neurosci
, vol.24
, pp. 9953-9961
-
-
Azad, S.C.1
-
35
-
-
0032563792
-
An analgesia circuit activated by cannabinoids
-
Meng, I.D., Manning, B.H., Martin, W.J. & Fields, H.L. An analgesia circuit activated by cannabinoids. Nature 395, 381-383 (1998).
-
(1998)
Nature
, vol.395
, pp. 381-383
-
-
Meng, I.D.1
Manning, B.H.2
Martin, W.J.3
Fields, H.L.4
-
36
-
-
0043073239
-
Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats
-
Finn, D.P. et al. Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats. Neuropharmacology 45, 594-604 (2003).
-
(2003)
Neuropharmacology
, vol.45
, pp. 594-604
-
-
Finn, D.P.1
-
37
-
-
0033027735
-
Spinal cannabinoids are anti-allodynic in rats with persistent inflammation
-
Martin, W.J., Loo, C.M. & Basbaum, A.I. Spinal cannabinoids are anti-allodynic in rats with persistent inflammation. Pain 82, 199-205 (1999).
-
(1999)
Pain
, vol.82
, pp. 199-205
-
-
Martin, W.J.1
Loo, C.M.2
Basbaum, A.I.3
-
38
-
-
0032537734
-
Control of pain initiation by endogenous cannabinoids
-
Calignano, A., La Rana, G., Giuffrida, A. & Piomelli, D. Control of pain initiation by endogenous cannabinoids. Nature 394, 277-281 (1998).
-
(1998)
Nature
, vol.394
, pp. 277-281
-
-
Calignano, A.1
La Rana, G.2
Giuffrida, A.3
Piomelli, D.4
-
39
-
-
0030438459
-
Peripheral morphine analgesia: Synergy with central sites and a target of morphine tolerance
-
Kolesnikov, Y.A., Jain, S., Wilson, R. & Pasternak, G.W. Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance. J. Pharmacol. Exp. Ther. 279, 502-506 (1996).
-
(1996)
J. Pharmacol. Exp. Ther
, vol.279
, pp. 502-506
-
-
Kolesnikov, Y.A.1
Jain, S.2
Wilson, R.3
Pasternak, G.W.4
-
41
-
-
0037966402
-
Intraplantar injection of anandamide inhibits mechanically evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats
-
Sokal, D.M., Elmes, S.J., Kendall, D.A. & Chapman, V. Intraplantar injection of anandamide inhibits mechanically evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats. Neuropharmacology 45, 404-411 (2003).
-
(2003)
Neuropharmacology
, vol.45
, pp. 404-411
-
-
Sokal, D.M.1
Elmes, S.J.2
Kendall, D.A.3
Chapman, V.4
-
42
-
-
0034890340
-
Cannabinoids attenuate capsaicin-evoked hyperalgesia through spinal and peripheral mechanisms
-
Johanek, L.M. et al. Cannabinoids attenuate capsaicin-evoked hyperalgesia through spinal and peripheral mechanisms. Pain 93, 303-315 (2001).
-
(2001)
Pain
, vol.93
, pp. 303-315
-
-
Johanek, L.M.1
-
43
-
-
0141655147
-
Inhibition of inflammatory hyperalgesia by activation of peripheral CB2 cannabinoid receptors
-
Quartilho, A. et al. Inhibition of inflammatory hyperalgesia by activation of peripheral CB2 cannabinoid receptors. Anesthesiology 99, 955-960 (2003).
-
(2003)
Anesthesiology
, vol.99
, pp. 955-960
-
-
Quartilho, A.1
-
44
-
-
7444268551
-
The effect of WIN55,212-2, a cannabinoid agonist, on tactile allodynia in diabetic rats
-
Ulugol, A., Karadag, H.C., Ipci, Y., Tamer, M. & Dokmeci, I. The effect of WIN55,212-2, a cannabinoid agonist, on tactile allodynia in diabetic rats. Neurosci. Lett. 371, 167-170 (2004).
-
(2004)
Neurosci. Lett
, vol.371
, pp. 167-170
-
-
Ulugol, A.1
Karadag, H.C.2
Ipci, Y.3
Tamer, M.4
Dokmeci, I.5
-
45
-
-
33646814424
-
Cannabinoid receptors and endocannabinoids: Evidence for new players
-
Mackie, K. & Stella, N. Cannabinoid receptors and endocannabinoids: evidence for new players. AAPS J. 8, E298-E306 (2006).
-
(2006)
AAPS J
, vol.8
-
-
Mackie, K.1
Stella, N.2
-
46
-
-
0037417989
-
Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice
-
Wang, L., Liu, J., Harvey-White, J., Zimmer, A. & Kunos, G. Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice. Proc. Natl. Acad. Sci. USA 100, 1393-1398 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1393-1398
-
-
Wang, L.1
Liu, J.2
Harvey-White, J.3
Zimmer, A.4
Kunos, G.5
|