Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D

Biochemical Journal

Volumn 380, Issue 3, 2004, Pages 749-756

  Sun, Yong Xin ^a   Tsuboi, Kazuhito ^a   Okamoto, Yasuo ^a   Tonai, Takeharu ^b   Murakami, Makoto ^c   Kudo, Ichiro ^c   Ueda, Natsuo ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b National Hospital Organization   (Japan)

^c SHOWA UNIVERSITY   (Japan)

Author keywords

Anandamide; Endocannabinoid; Fatty acid; N acylethanolamine (NAE); N acylphosphatidylethanolamine; Phospholipase D (PLD)

Indexed keywords

AMINES; BIOSYNTHESIS; DISEASE CONTROL; ENZYME KINETICS; ENZYMES; HYDROLYSIS;

ANANDAMIDE; BIOACTIVITY;

BIOCHEMISTRY;

ANANDAMIDE; ENZYME; ETHANOLAMINE DERIVATIVE; LYSOPHOSPHOLIPASE D; N ACYL 1 ACYLLYSOPHOSPHATIDYLETHANOLAMINE; N ARACHIDONOYLLYSOPHOSPHATIDYLETHANOLAMINE; N ARACHIDONOYLPHOSPHATIDYLETHANOLAMINE; N PALMITOYLPHOSPHATIDYLETHANOLAMINE; PALMIDROL; PHOSPHOLIPASE A1; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 ALPHA; PROTEIN; SECRETORY PHOSPHOLIPASE A2 1B; SECRETORY PHOSPHOLIPASE A2 IIA; SECRETORY PHOSPHOLIPASE A2 V; SECRETORY PHOSPHOLIPASE A2 X; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BRAIN; BRAIN HOMOGENATE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INACTIVATION; ENZYME SUBSTRATE; HYDROLYSIS; MALE; NONHUMAN; PRECURSOR; PRIORITY JOURNAL; RAT; STOMACH; TESTIS; TISSUE;

ANIMALS; ARACHIDONIC ACIDS; BRAIN; CELL LINE; ETHANOLAMINES; HUMANS; HYDROLYSIS; ISOENZYMES; KIDNEY; MALE; ORGAN SPECIFICITY; PALMITIC ACIDS; PHOSPHATIDYLETHANOLAMINES; PHOSPHOLIPASES A; PHOSPHORIC DIESTER HYDROLASES; POLYUNSATURATED ALKAMIDES; RATS; RATS, WISTAR; STOMACH; SUBSTRATE SPECIFICITY;

ANIMALIA;

EID: 3042737612     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20040031     Document Type: Article

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