Aggregated and monomeric α-synuclein bind to the S6′ proteasomal protein and inhibit proteasomal function

Journal of Biological Chemistry

Volumn 278, Issue 14, 2003, Pages 11753-11759

  Snyder, Heather ^a   Mensah, Kwame ^b   Theisler, Catherine ^a   Lee, Jack ^a   Matouschek, Andreas ^b   Wolozin, Benjamin ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; DISEASES; MONOMERS;

PROTEASOMAL PROTEINS;

PROTEINS;

20S PROTEASOME; 26S PROTEASOME; ALPHA SYNUCLEIN; PROTEASOMAL PROTEIN S6'; PROTEOME; UBIQUITIN; UNCLASSIFIED DRUG; CYSTEINE PROTEINASE; MULTIENZYME COMPLEX; NERVE PROTEIN; PROTEASOME; SNCA PROTEIN, HUMAN; SYNUCLEIN;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; CELL CULTURE; CYTOLOGY; DRUG EFFECT; ENZYME ACTIVATION; GENE EXPRESSION; GENETICS; KIDNEY; METABOLISM; NEUROBLASTOMA; PHYSIOLOGY;

ALPHA-SYNUCLEIN; CYSTEINE ENDOPEPTIDASES; ENZYME ACTIVATION; GENE EXPRESSION; HUMANS; KIDNEY; MULTIENZYME COMPLEXES; NERVE TISSUE PROTEINS; NEUROBLASTOMA; PARKINSON DISEASE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; SYNUCLEINS; TUMOR CELLS, CULTURED; UBIQUITIN;

EID: 0038413759     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208641200     Document Type: Article

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