메뉴 건너뛰기




Volumn 12, Issue 12, 2003, Pages 1427-1437

The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: Linking protein biosynthesis and neurodegeneration

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; PARKIN; PROTEASOME; PROTEIN SUBUNIT; SYNAPTOPHYSIN; UBIQUITIN PROTEIN LIGASE;

EID: 10744220754     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (228)

References (60)
  • 1
    • 0029981526 scopus 로고    scopus 로고
    • Neuropathology of Parkinson's disease
    • Forno, L.S. (1996) Neuropathology of Parkinson's disease. J. Neuropathol. Exp. Neurol., 55, 259-272.
    • (1996) J. Neuropathol. Exp. Neurol. , vol.55 , pp. 259-272
    • Forno, L.S.1
  • 2
    • 0036591668 scopus 로고    scopus 로고
    • Genetics of Parkinson's disease and biochemical studies of implicated gene products
    • Brice, A. and Lansbury, P.T.J. (2002) Genetics of Parkinson's disease and biochemical studies of implicated gene products. Curr. Opin. Genet. Devel., 12, 229-306.
    • (2002) Curr. Opin. Genet. Devel. , vol.12 , pp. 229-306
    • Brice, A.1    Lansbury, P.T.J.2
  • 6
    • 0031910093 scopus 로고    scopus 로고
    • Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: Implications for the pathogenesis of Parkinson disease and Lewy body dementia
    • Trojanowski, J.Q. and Lee, V.M. (1998) Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia. Arch. Neurol., 55, 151-152.
    • (1998) Arch. Neurol. , vol.55 , pp. 151-152
    • Trojanowski, J.Q.1    Lee, V.M.2
  • 10
    • 0031753976 scopus 로고    scopus 로고
    • Deletions in the Parkin gene and genetic heterogeneity in a Greek family with early onset Parkinson's disease
    • Leroy, E., Anastasopoulos, D., Konitsiotis, S., Lavedan, C. and Polymeropoulos, M.H. (1998) Deletions in the Parkin gene and genetic heterogeneity in a Greek family with early onset Parkinson's disease. Hum. Genet., 103, 424-427.
    • (1998) Hum. Genet. , vol.103 , pp. 424-427
    • Leroy, E.1    Anastasopoulos, D.2    Konitsiotis, S.3    Lavedan, C.4    Polymeropoulos, M.H.5
  • 11
    • 0345490853 scopus 로고    scopus 로고
    • A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe
    • French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease
    • Abbas, N., Lücking, C.B., Ricard, S., Durr, A., Bonifati, V., De Michele, G., Bouley, S., Vaughan, J. R., Gasser, T., Marconi, R. et al. (1999) A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease. Hum. Mol. Genet., 8, 567-574.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 567-574
    • Abbas, N.1    Lücking, C.B.2    Ricard, S.3    Durr, A.4    Bonifati, V.5    De Michele, G.6    Bouley, S.7    Vaughan, J.R.8    Gasser, T.9    Marconi, R.10
  • 12
    • 0032564235 scopus 로고    scopus 로고
    • Homozygous deletions in parkin gene in European and North African families with autosomal recessive juvenile parkinsonism
    • The European Consortium on Genetic Susceptibility in Parkinson's Disease and the French Parkinson's Disease Genetics Study Group
    • Lücking, C.B., Abbas, N., Durr, A., Bonifati, V., Bonnet, A.M., de Broucker, T., De Michele, G., Wood. N.W., Agid. Y. and Brice, A. (1998) Homozygous deletions in parkin gene in European and North African families with autosomal recessive juvenile parkinsonism. The European Consortium on Genetic Susceptibility in Parkinson's Disease and the French Parkinson's Disease Genetics Study Group. Lancet, 352, 1355-1356.
    • (1998) Lancet , vol.352 , pp. 1355-1356
    • Lücking, C.B.1    Abbas, N.2    Durr, A.3    Bonifati, V.4    Bonnet, A.M.5    de Broucker, T.6    De Michele, G.7    Wood, N.W.8    Agid, Y.9    Brice, A.10
  • 18
    • 0034266806 scopus 로고    scopus 로고
    • RING finger proteins: Mediators of ubiquitin ligase activity
    • Joazeiro, C.A. and Weissman, A.M. (2000) RING finger proteins: mediators of ubiquitin ligase activity. Cell, 102, 549-552.
    • (2000) Cell , vol.102 , pp. 549-552
    • Joazeiro, C.A.1    Weissman, A.M.2
  • 20
    • 0034680913 scopus 로고    scopus 로고
    • Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
    • Imai, Y., Soda, M. and Takahashi, R. (2000) Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J. Biol. Chem., 275, 35661-35664.
    • (2000) J. Biol. Chem. , vol.275 , pp. 35661-35664
    • Imai, Y.1    Soda, M.2    Takahashi, R.3
  • 21
    • 0034700158 scopus 로고    scopus 로고
    • Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
    • Zhang, Y., Gao, J., Chung, K.K., Huang, H., Dawson, V.L. and Dawson, T.M. (2000) Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc. Natl Acad Sci. USA, 97, 13354-13359.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13354-13359
    • Zhang, Y.1    Gao, J.2    Chung, K.K.3    Huang, H.4    Dawson, V.L.5    Dawson, T.M.6
  • 22
    • 0035967883 scopus 로고    scopus 로고
    • An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
    • Imai, Y., Soda, M., Inoue, H., Hattori, N., Mizuno, Y. and Takahashi, R. (2001) An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell, 105, 891-902.
    • (2001) Cell , vol.105 , pp. 891-902
    • Imai, Y.1    Soda, M.2    Inoue, H.3    Hattori, N.4    Mizuno, Y.5    Takahashi, R.6
  • 23
    • 0034776095 scopus 로고    scopus 로고
    • Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease
    • Chung, K.K., Zhang, Y., Lim, K.L., Tanaka, Y., Huang, H., Gao, J., Ross, C.A., Dawson, V.L. and Dawson, T.M. (2001) Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat. Med., 7, 1144-1150.
    • (2001) Nat. Med. , vol.7 , pp. 1144-1150
    • Chung, K.K.1    Zhang, Y.2    Lim, K.L.3    Tanaka, Y.4    Huang, H.5    Gao, J.6    Ross, C.A.7    Dawson, V.L.8    Dawson, T.M.9
  • 25
    • 0037422010 scopus 로고    scopus 로고
    • Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
    • Staropoli, J.F., McDermott, C., Martinat, C., Schulman, B., Demireva, E. and Abeliovich, A. (2003) Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity. Neuron, 37, 735-749.
    • (2003) Neuron , vol.37 , pp. 735-749
    • Staropoli, J.F.1    McDermott, C.2    Martinat, C.3    Schulman, B.4    Demireva, E.5    Abeliovich, A.6
  • 26
    • 0033534561 scopus 로고    scopus 로고
    • Macromolecular assemblage of aminoacyl-tRNA synthetases: Identification of protein-protein interactions and characterization of a core protein
    • Quevillon, S., Robinson, J.C., Berthonneau, E., Siatecka, M. and Mirande, M. (1999) Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. J. Mol. Biol., 285, 183-195.
    • (1999) J. Mol. Biol. , vol.285 , pp. 183-195
    • Quevillon, S.1    Robinson, J.C.2    Berthonneau, E.3    Siatecka, M.4    Mirande, M.5
  • 27
    • 0034671360 scopus 로고    scopus 로고
    • Macromolecular assemblage of aminoacyl-tRNA synthetases: Quantitative analysis of protein-protein interactions and mechanism of complex assembly
    • Robinson, J.C., Kerjan, P. and Mirande, M. (2000) Macromolecular assemblage of aminoacyl-tRNA synthetases: quantitative analysis of protein-protein interactions and mechanism of complex assembly. J. Mol. Biol., 304, 983-994.
    • (2000) J. Mol. Biol. , vol.304 , pp. 983-994
    • Robinson, J.C.1    Kerjan, P.2    Mirande, M.3
  • 28
    • 0029100814 scopus 로고
    • Analysis of the 5′ region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene
    • Nicolaides, N.C., Kinzler, K.W. and Vogelstein, B. (1995) Analysis of the 5′ region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene. Genomics, 29, 329-334.
    • (1995) Genomics , vol.29 , pp. 329-334
    • Nicolaides, N.C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 29
    • 0033621047 scopus 로고    scopus 로고
    • Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity
    • Meng, L., Mohan, R., Kwok, B.H., Elofsson, M., Sin, N. and Crews, C.M. (1999) Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. Proc. Natl Acad. Sci. USA, 96, 10403-10408.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10403-10408
    • Meng, L.1    Mohan, R.2    Kwok, B.H.3    Elofsson, M.4    Sin, N.5    Crews, C.M.6
  • 30
    • 0032576605 scopus 로고    scopus 로고
    • Aggresomes: A cellular response to misfolded proteins
    • Johnston, J.A., Ward, C.L. and Kopito, R.R. (1998) Aggresomes: a cellular response to misfolded proteins. J. Cell. Biol., 143, 1883-1898.
    • (1998) J. Cell. Biol. , vol.143 , pp. 1883-1898
    • Johnston, J.A.1    Ward, C.L.2    Kopito, R.R.3
  • 31
    • 0034578389 scopus 로고    scopus 로고
    • Aggresomes, inclusion bodies and protein aggregation
    • Kopito, R.R. (2000) Aggresomes, inclusion bodies and protein aggregation. Trends Cell. Biol., 10, 524-530.
    • (2000) Trends Cell. Biol. , vol.10 , pp. 524-530
    • Kopito, R.R.1
  • 32
    • 0037065732 scopus 로고    scopus 로고
    • Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a
    • Walters, K.J., Kleijnen, M.F., Goh, A.M., Wagner, G. and Howley, P.M. (2002) Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a. Biochemistry, 41, 1767-1777.
    • (2002) Biochemistry , vol.41 , pp. 1767-1777
    • Walters, K.J.1    Kleijnen, M.F.2    Goh, A.M.3    Wagner, G.4    Howley, P.M.5
  • 34
    • 0037047311 scopus 로고    scopus 로고
    • Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome
    • Hyun, D.H., Lee, M., Hattori, N., Kubo, S., Mizuno, Y., Halliwell, B. and Jenner, P. (2002) Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome. J. Biol. Chem., 277, 28572-28577.
    • (2002) J. Biol. Chem. , vol.277 , pp. 28572-28577
    • Hyun, D.H.1    Lee, M.2    Hattori, N.3    Kubo, S.4    Mizuno, Y.5    Halliwell, B.6    Jenner, P.7
  • 35
    • 0034834665 scopus 로고    scopus 로고
    • E3 ubiquitin-protein ligase activity of Parkin is dependent on cooperative interaction of RING finger (TRIAD) elements
    • Rankin, C.A., Joazeiro, C.A., Floor, E. and Hunter, T. (2001) E3 ubiquitin-protein ligase activity of Parkin is dependent on cooperative interaction of RING finger (TRIAD) elements. J. Biomed. Sci., 8, 421-429.
    • (2001) J. Biomed. Sci. , vol.8 , pp. 421-429
    • Rankin, C.A.1    Joazeiro, C.A.2    Floor, E.3    Hunter, T.4
  • 36
    • 0036345454 scopus 로고    scopus 로고
    • CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity
    • Imai, Y., Soda, M., Hatakeyama, S., Akagi, T., Hashikawa, T., Nakayama, K.I. and Takahashi, R. (2002) CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol. Cell, 10, 55-67.
    • (2002) Mol. Cell , vol.10 , pp. 55-67
    • Imai, Y.1    Soda, M.2    Hatakeyama, S.3    Akagi, T.4    Hashikawa, T.5    Nakayama, K.I.6    Takahashi, R.7
  • 38
    • 0031474418 scopus 로고    scopus 로고
    • Contribution of somal Lewy bodies to neuronal death
    • Tompkins, M.M. and Hill, W.D. (1997) Contribution of somal Lewy bodies to neuronal death. Brain Res., 775, 24-29.
    • (1997) Brain Res. , vol.775 , pp. 24-29
    • Tompkins, M.M.1    Hill, W.D.2
  • 39
    • 0025930249 scopus 로고
    • Aminoacyl-tRNA synthetase family from prokaryotes and eukaryotes: Structural domains and their implications
    • Mirande, M. (1991) Aminoacyl-tRNA synthetase family from prokaryotes and eukaryotes: structural domains and their implications. Prog. Nucl. Acid Res. Mol. Biol., 40, 95-142.
    • (1991) Prog. Nucl. Acid Res. Mol. Biol. , vol.40 , pp. 95-142
    • Mirande, M.1
  • 41
    • 0037062472 scopus 로고    scopus 로고
    • p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: Implications for its physiological significance
    • Kim, J.Y., Kang, Y.S., Lee, J.W., Kim, H.J., Ahn, Y.H., Park, H., Ko, Y.G. and Kim, S. (2002) p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: implications for its physiological significance. Proc. Natl Acad. Sci. USA, 99, 7912-7916.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 7912-7916
    • Kim, J.Y.1    Kang, Y.S.2    Lee, J.W.3    Kim, H.J.4    Ahn, Y.H.5    Park, H.6    Ko, Y.G.7    Kim, S.8
  • 42
    • 0034241025 scopus 로고    scopus 로고
    • Non-canonical functions of aminoacyl-tRNA synthetases
    • Ivanov, K.A., Moor, N.A. and Lavrik, O.I. (2000) Non-canonical functions of aminoacyl-tRNA synthetases. Biochemistry (Mosc.), 65, 888-897.
    • (2000) Biochemistry (Mosc.) , vol.65 , pp. 888-897
    • Ivanov, K.A.1    Moor, N.A.2    Lavrik, O.I.3
  • 43
    • 0035937134 scopus 로고    scopus 로고
    • Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1
    • Ko, Y.G., Kim, E.Y., Kim, T., Park, H., Park, H.S., Choi, E.J. and Kim, S. (2001) Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1. J. Biol. Chem., 276, 6030-6036.
    • (2001) J. Biol. Chem. , vol.276 , pp. 6030-6036
    • Ko, Y.G.1    Kim, E.Y.2    Kim, T.3    Park, H.4    Park, H.S.5    Choi, E.J.6    Kim, S.7
  • 44
    • 0033551781 scopus 로고    scopus 로고
    • Highly differentiated motifs responsible for two cytokine activities of a split human tRNA synthetase
    • Wakasugi, K. and Schimmel, P. (1999) Highly differentiated motifs responsible for two cytokine activities of a split human tRNA synthetase. J. Biol. Chem., 274, 23155-13159.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13159-23155
    • Wakasugi, K.1    Schimmel, P.2
  • 45
    • 0033515887 scopus 로고    scopus 로고
    • Two distinct cytokines released from a human aminoacyl-tRNA synthetase
    • Wakasugi, K. and Schimmel, P. (1999) Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Science, 284, 147-151.
    • (1999) Science , vol.284 , pp. 147-151
    • Wakasugi, K.1    Schimmel, P.2
  • 46
    • 0026781869 scopus 로고
    • Endothelial monocyte-activating polypeptide II. A novel tumor-derived polypeptide that activates host-response mechanisms
    • Kao, J., Ryan, J., Brett, G., Chen, J., Shen, H., Fan, Y.G., Godman, G., Familletti, P.C., Wang, F., Pan, Y.C. et al. (1992) Endothelial monocyte-activating polypeptide II. A novel tumor-derived polypeptide that activates host-response mechanisms. J. Biol. Chem., 267, 20239-20247.
    • (1992) J. Biol. Chem. , vol.267 , pp. 20239-20247
    • Kao, J.1    Ryan, J.2    Brett, G.3    Chen, J.4    Shen, H.5    Fan, Y.G.6    Godman, G.7    Familletti, P.C.8    Wang, F.9    Pan, Y.C.10
  • 47
    • 0031464187 scopus 로고    scopus 로고
    • The p43 component of the mammalian multi-synthetase complex is likely to be the precursor of the endothelial monocyte-activating polypeptide II cytokine
    • Quevillon, S., Agou, F., Robinson, J.C. and Mirande, M. (1997) The p43 component of the mammalian multi-synthetase complex is likely to be the precursor of the endothelial monocyte-activating polypeptide II cytokine. J. Biol. Chem., 272, 32573-32579.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32573-32579
    • Quevillon, S.1    Agou, F.2    Robinson, J.C.3    Mirande, M.4
  • 48
    • 0000666250 scopus 로고    scopus 로고
    • Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase
    • Park, S.G., Jung, K.H., Lee, J.S., Jo, Y.J., Motegi, H., Kim, S. and Shiba, K. (1999) Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase. J. Biol. Chem., 274, 16673-16676.
    • (1999) J. Biol. Chem. , vol.274 , pp. 16673-16676
    • Park, S.G.1    Jung, K.H.2    Lee, J.S.3    Jo, Y.J.4    Motegi, H.5    Kim, S.6    Shiba, K.7
  • 49
    • 0035968226 scopus 로고    scopus 로고
    • The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component
    • Shalak, V., Kaminska, M., Mitnacht-Kraus, R., Vandenabeele, P., Clauss, M. and Mirande, M. (2001) The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component. J. Biol. Chem., 276, 23769-23776.
    • (2001) J. Biol. Chem. , vol.276 , pp. 23769-23776
    • Shalak, V.1    Kaminska, M.2    Mitnacht-Kraus, R.3    Vandenabeele, P.4    Clauss, M.5    Mirande, M.6
  • 51
    • 0036434197 scopus 로고    scopus 로고
    • Expression of EMAP-II by activated monocytes/microglial cells in different regions of the rat hippocampus after trimethyltin-induced brain damage
    • Brabeck, C., Michetti, F., Geloso, M.C., Corvino, V., Goezalan, F., Meyermann, R. and Schluesener, H.J. (2002) Expression of EMAP-II by activated monocytes/microglial cells in different regions of the rat hippocampus after trimethyltin-induced brain damage. Exp. Neurol., 177, 341-346.
    • (2002) Exp. Neurol. , vol.177 , pp. 341-346
    • Brabeck, C.1    Michetti, F.2    Geloso, M.C.3    Corvino, V.4    Goezalan, F.5    Meyermann, R.6    Schluesener, H.J.7
  • 53
    • 0030272844 scopus 로고    scopus 로고
    • The compartmentalization of protein synthesis: Importance of cytoskeleton and role in mRNA targeting
    • Hovland, R., Hesketh, J.E. and Pryme, I.F. (1996) The compartmentalization of protein synthesis: importance of cytoskeleton and role in mRNA targeting. Biochem. Cell. Biol., 28, 1089-1105.
    • (1996) Biochem. Cell. Biol. , vol.28 , pp. 1089-1105
    • Hovland, R.1    Hesketh, J.E.2    Pryme, I.F.3
  • 54
    • 0035910634 scopus 로고    scopus 로고
    • Proteasomal function is impaired in substantia nigra in Parkinson's disease
    • McNaught, K.S. and Jenner, P. (2001) Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci. Lett., 297, 191-194.
    • (2001) Neurosci. Lett. , vol.297 , pp. 191-194
    • McNaught, K.S.1    Jenner, P.2
  • 55
    • 0037025111 scopus 로고    scopus 로고
    • Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease
    • McNaught, K.S., Belizaire, R., Jenner, P., Olanow, C.W., Isacson, O. (2002) Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Parkinson's disease. Neurosci. Lett., 326, 155-158.
    • (2002) Neurosci. Lett. , vol.326 , pp. 155-158
    • McNaught, K.S.1    Belizaire, R.2    Jenner, P.3    Olanow, C.W.4    Isacson, O.5
  • 56
    • 2942618660 scopus 로고    scopus 로고
    • The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders
    • Chung, K.K., Dawson, V.L. and Dawson, T.M. (2001) The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders. Trends Neurosci., 24, S7-S14.
    • (2001) Trends Neurosci. , vol.24
    • Chung, K.K.1    Dawson, V.L.2    Dawson, T.M.3
  • 59
    • 0033121299 scopus 로고    scopus 로고
    • FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells
    • Hunot, S., Dugas, N., Faucheux, B., Hartmann, A., Tardieu, M., Debre, P., Agid, Y., Dugas, B. and Hirsch, E.C. (1999) FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells. J. Neurosci., 19, 3440-3447.
    • (1999) J. Neurosci. , vol.19 , pp. 3440-3447
    • Hunot, S.1    Dugas, N.2    Faucheux, B.3    Hartmann, A.4    Tardieu, M.5    Debre, P.6    Agid, Y.7    Dugas, B.8    Hirsch, E.C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.