메뉴 건너뛰기




Volumn 170, Issue 2, 2007, Pages 658-666

Pesticide exposure exacerbates α-synucleinopathy in an A53T transgenic mouse model

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; MANEB; MUTANT PROTEIN; PARAQUAT; PESTICIDE; FUNGICIDE; SNCA PROTEIN, HUMAN; UNCLASSIFIED DRUG;

EID: 33947513592     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2007.060359     Document Type: Article
Times cited : (116)

References (52)
  • 1
    • 2642514788 scopus 로고    scopus 로고
    • Alpha-synuclein: Normal function and role in neurodegenerative diseases
    • Norris EH, Giasson BI, Lee VMY: Alpha-synuclein: normal function and role in neurodegenerative diseases. Curr Top Dev Biol 2004, 60:17-54
    • (2004) Curr Top Dev Biol , vol.60 , pp. 17-54
    • Norris, E.H.1    Giasson, B.I.2    Lee, V.M.Y.3
  • 3
    • 23744443327 scopus 로고    scopus 로고
    • Nosology of Parkinson's disease: Looking for the way out of a quagmire
    • Forman MS, Lee VMY, Trojanowski JQ: Nosology of Parkinson's disease: looking for the way out of a quagmire. Neuron 2005, 47:479-482
    • (2005) Neuron , vol.47 , pp. 479-482
    • Forman, M.S.1    Lee, V.M.Y.2    Trojanowski, J.Q.3
  • 5
    • 0038051345 scopus 로고    scopus 로고
    • Mitochondria, oxidative damage, and inflammation in Parkinson's disease
    • Beal MF: Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Ann NY Acad Sci 2003, 991:120-131
    • (2003) Ann NY Acad Sci , vol.991 , pp. 120-131
    • Beal, M.F.1
  • 7
    • 0023175904 scopus 로고
    • Environmental and genetic factors in the etiology of Parkinson's disease
    • Barbeau PA, Cloutier T, Plasse L, Paris S: Environmental and genetic factors in the etiology of Parkinson's disease. Adv Neurol 1986, 45:299-306
    • (1986) Adv Neurol , vol.45 , pp. 299-306
    • Barbeau, P.A.1    Cloutier, T.2    Plasse, L.3    Paris, S.4
  • 8
    • 0023097950 scopus 로고
    • Ecogenetics of Parkinson's disease: Prevalence and environmental aspects in rural areas
    • Barbeau A, Roy M, Bernier G, Campanella G, Paris S: Ecogenetics of Parkinson's disease: prevalence and environmental aspects in rural areas. Can J Neurol Sci 1987, 14:36-41
    • (1987) Can J Neurol Sci , vol.14 , pp. 36-41
    • Barbeau, A.1    Roy, M.2    Bernier, G.3    Campanella, G.4    Paris, S.5
  • 9
    • 0025230379 scopus 로고
    • Parkinson's disease: A case-control study of occupational and environmental risk factors
    • Hertzman C, Weins M, Bowering D, Snow B, Calne D: Parkinson's disease: a case-control study of occupational and environmental risk factors. Am J Ind Med 1990, 17:349-355
    • (1990) Am J Ind Med , vol.17 , pp. 349-355
    • Hertzman, C.1    Weins, M.2    Bowering, D.3    Snow, B.4    Calne, D.5
  • 10
    • 0026524695 scopus 로고
    • Exposure to well water and pesticides in Parkinson's disease: A case-control study in the Madrid area
    • Jimenez-Jimenez FJ, Mateo D, Gimenez-Roldman S: Exposure to well water and pesticides in Parkinson's disease: a case-control study in the Madrid area. Mov Disord 1992, 7:149-152
    • (1992) Mov Disord , vol.7 , pp. 149-152
    • Jimenez-Jimenez, F.J.1    Mateo, D.2    Gimenez-Roldman, S.3
  • 12
    • 0023882918 scopus 로고
    • Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication
    • Ferraz HB, Bertolucci PH, Pereira JS, Lima JG, Andrade LA: Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication. Neurology 1988, 38:550-553
    • (1988) Neurology , vol.38 , pp. 550-553
    • Ferraz, H.B.1    Bertolucci, P.H.2    Pereira, J.S.3    Lima, J.G.4    Andrade, L.A.5
  • 13
    • 0028064283 scopus 로고
    • Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate)
    • Meco G, Bonifati V, Vanacore N, Fabrizio E: Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate). Scand J Work Environ Health 1994, 20:301-305
    • (1994) Scand J Work Environ Health , vol.20 , pp. 301-305
    • Meco, G.1    Bonifati, V.2    Vanacore, N.3    Fabrizio, E.4
  • 14
    • 0037237927 scopus 로고    scopus 로고
    • Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
    • Ischiropoulos H, Beckman JS: Oxidative stress and nitration in neurodegeneration: cause, effect, or association? J Clin Invest 2003, 111:163-169
    • (2003) J Clin Invest , vol.111 , pp. 163-169
    • Ischiropoulos, H.1    Beckman, J.S.2
  • 16
    • 0027360342 scopus 로고
    • Neonatal exposure to paraquat or MPTP induces permanent changes in striatum dopamine and behavior in adult mice
    • Fredriksson A, Fredriksson M, Eriksson P: Neonatal exposure to paraquat or MPTP induces permanent changes in striatum dopamine and behavior in adult mice. Toxicol Appl Pharmacol 1993, 122:258-264
    • (1993) Toxicol Appl Pharmacol , vol.122 , pp. 258-264
    • Fredriksson, A.1    Fredriksson, M.2    Eriksson, P.3
  • 17
    • 0029918777 scopus 로고    scopus 로고
    • Effects of paraquat on the substantia nigra of the Wistar rats: Neurochemical, histological, and behavioral studies
    • Liou HH, Chen RC, Tsai YF, Chen WP, Chang YC, Tsai MC: Effects of paraquat on the substantia nigra of the Wistar rats: neurochemical, histological, and behavioral studies. Toxicol Appl Pharmacol 1996, 137:34-41
    • (1996) Toxicol Appl Pharmacol , vol.137 , pp. 34-41
    • Liou, H.H.1    Chen, R.C.2    Tsai, Y.F.3    Chen, W.P.4    Chang, Y.C.5    Tsai, M.C.6
  • 18
    • 0037127197 scopus 로고    scopus 로고
    • The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: Paraquat and alpha-synuclein
    • Manning-Bog AB, McCormack AL, Li J, Uversky VN, Fink AL, Di Monte DA: The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein. J Biol Chem 2002, 277:1641-1644
    • (2002) J Biol Chem , vol.277 , pp. 1641-1644
    • Manning-Bog, A.B.1    McCormack, A.L.2    Li, J.3    Uversky, V.N.4    Fink, A.L.5    Di Monte, D.A.6
  • 20
    • 0035816404 scopus 로고    scopus 로고
    • Pesticides directly accelerate the rate of alpha-synuclein fibril formation: A possible factor in Parkinson's disease
    • Uversky VN, Li J, Fink AL: Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease. FEBS Lett 2001, 500:105-108
    • (2001) FEBS Lett , vol.500 , pp. 105-108
    • Uversky, V.N.1    Li, J.2    Fink, A.L.3
  • 22
    • 0024829856 scopus 로고
    • Acute exposure to maneb alters some behavioral functions in the mouse
    • Morato GS, Lemos T, Takahashi RN: Acute exposure to maneb alters some behavioral functions in the mouse. Neurotoxicol Teratol 1989, 11:421-425
    • (1989) Neurotoxicol Teratol , vol.11 , pp. 421-425
    • Morato, G.S.1    Lemos, T.2    Takahashi, R.N.3
  • 23
    • 0037265974 scopus 로고    scopus 로고
    • Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: A link through mitochondrial dysfunction
    • Zhang J, Fitsanakis VA, Gu G, Jing D, Ao M, Amarnath V, Montine TJ: Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: a link through mitochondrial dysfunction. J Neurochem 2003, 84:336-346
    • (2003) J Neurochem , vol.84 , pp. 336-346
    • Zhang, J.1    Fitsanakis, V.A.2    Gu, G.3    Jing, D.4    Ao, M.5    Amarnath, V.6    Montine, T.J.7
  • 24
    • 4444225471 scopus 로고    scopus 로고
    • Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: Relevance to Parkinson's disease
    • Zhou Y, Shie FS, Piccardo P, Montine TJ, Zhang J: Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: relevance to Parkinson's disease. Neuroscience 2004, 128:281-291
    • (2004) Neuroscience , vol.128 , pp. 281-291
    • Zhou, Y.1    Shie, F.S.2    Piccardo, P.3    Montine, T.J.4    Zhang, J.5
  • 25
    • 0034671469 scopus 로고    scopus 로고
    • The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: Implications for Parkinson's disease
    • Thiruchelvam M, Richfield EK, Baggs RB, Tank AW, Cory-Slechta DA: The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease. J Neurosci 2000, 20:9207-9214
    • (2000) J Neurosci , vol.20 , pp. 9207-9214
    • Thiruchelvam, M.1    Richfield, E.K.2    Baggs, R.B.3    Tank, A.W.4    Cory-Slechta, D.A.5
  • 27
    • 0042421940 scopus 로고    scopus 로고
    • Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype
    • Thiruchelvam M, McCormack A, Richfield EK, Baggs RB, Tank AW, Di Monte DA, Cory-Slechta DA: Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype. Eur J Neurosci 2003, 18:589-600
    • (2003) Eur J Neurosci , vol.18 , pp. 589-600
    • Thiruchelvam, M.1    McCormack, A.2    Richfield, E.K.3    Baggs, R.B.4    Tank, A.W.5    Di Monte, D.A.6    Cory-Slechta, D.A.7
  • 28
    • 0037118259 scopus 로고    scopus 로고
    • Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
    • Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VMY: Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 2002, 34:521-533
    • (2002) Neuron , vol.34 , pp. 521-533
    • Giasson, B.I.1    Duda, J.E.2    Quinn, S.M.3    Zhang, B.4    Trojanowski, J.Q.5    Lee, V.M.Y.6
  • 30
    • 0036322266 scopus 로고    scopus 로고
    • Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases
    • Duda JE, Giasson BI, Mabon ME, Lee VMY, Trojanowski JQ: Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases. Ann Neurol 2002, 52:205-210
    • (2002) Ann Neurol , vol.52 , pp. 205-210
    • Duda, J.E.1    Giasson, B.I.2    Mabon, M.E.3    Lee, V.M.Y.4    Trojanowski, J.Q.5
  • 32
    • 0023228210 scopus 로고
    • Phosphate dependent and independent neurofilament epitopes in the axonal swellings of patients with motor neuron disease and controls
    • Schmidt ML, Carden MJ, Lee VMY, Trojanowski JQ: Phosphate dependent and independent neurofilament epitopes in the axonal swellings of patients with motor neuron disease and controls. Lab Invest 1987, 56:282-294
    • (1987) Lab Invest , vol.56 , pp. 282-294
    • Schmidt, M.L.1    Carden, M.J.2    Lee, V.M.Y.3    Trojanowski, J.Q.4
  • 33
    • 0024529404 scopus 로고
    • Distribution of tau proteins in the normal human central and peripheral nervous system
    • Trojanowski JQ, Schuck T, Schmidt ML, Lee VMY: Distribution of tau proteins in the normal human central and peripheral nervous system. J Histochem Cytochem 1989, 37:209-215
    • (1989) J Histochem Cytochem , vol.37 , pp. 209-215
    • Trojanowski, J.Q.1    Schuck, T.2    Schmidt, M.L.3    Lee, V.M.Y.4
  • 35
    • 0033539664 scopus 로고    scopus 로고
    • Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein
    • Galvin JE, Uryu K, Lee VMY, Trojanowski JQ: Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein. Proc Natl Acad Sci USA 1999, 96:13450-13455
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13450-13455
    • Galvin, J.E.1    Uryu, K.2    Lee, V.M.Y.3    Trojanowski, J.Q.4
  • 36
    • 33746089104 scopus 로고    scopus 로고
    • Rat model of Parkinson's disease: Chronic central delivery of 1-methyl-4- phenylpyridinium (MPP(+))
    • Yazdani U, German DC, Liang CL, Manzino L, Sonsalla PK, Zeevalk GD: Rat model of Parkinson's disease: chronic central delivery of 1-methyl-4- phenylpyridinium (MPP(+)). Exp Neurol 2006, 200: 172-183
    • (2006) Exp Neurol , vol.200 , pp. 172-183
    • Yazdani, U.1    German, D.C.2    Liang, C.L.3    Manzino, L.4    Sonsalla, P.K.5    Zeevalk, G.D.6
  • 37
    • 0033583215 scopus 로고    scopus 로고
    • Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro
    • Giasson BI, Uryu K, Trojanowski JQ, Lee VMY: Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro. J Biol Chem 1999, 274:7619-7622
    • (1999) J Biol Chem , vol.274 , pp. 7619-7622
    • Giasson, B.I.1    Uryu, K.2    Trojanowski, J.Q.3    Lee, V.M.Y.4
  • 38
    • 0025942723 scopus 로고    scopus 로고
    • Hattori N, Tanaka M, Ozawa T, Mizuno Y: Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease. Ann Neurol 1991, 30:563-571
    • Hattori N, Tanaka M, Ozawa T, Mizuno Y: Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease. Ann Neurol 1991, 30:563-571
  • 40
    • 0026718086 scopus 로고
    • Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease
    • Mann VM, Cooper JM, Krige D, Daniel SE, Schapira AH, Marsden CD: Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease. Brain 1992, 115:333-342
    • (1992) Brain , vol.115 , pp. 333-342
    • Mann, V.M.1    Cooper, J.M.2    Krige, D.3    Daniel, S.E.4    Schapira, A.H.5    Marsden, C.D.6
  • 43
    • 17644426350 scopus 로고    scopus 로고
    • Role of oxidative damage in protein aggregation associated with Parkinson's disease and related disorders
    • Norris EH, Giasson BI: Role of oxidative damage in protein aggregation associated with Parkinson's disease and related disorders. Antioxid Redox Signal 2005, 7:672-684
    • (2005) Antioxid Redox Signal , vol.7 , pp. 672-684
    • Norris, E.H.1    Giasson, B.I.2
  • 47
    • 0037229425 scopus 로고    scopus 로고
    • Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation
    • Sherer TB, Kim JH, Betarbet R, Greenamyre JT: Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation. Exp Neurol 2003, 179:9-16
    • (2003) Exp Neurol , vol.179 , pp. 9-16
    • Sherer, T.B.1    Kim, J.H.2    Betarbet, R.3    Greenamyre, J.T.4
  • 50
    • 4344659685 scopus 로고    scopus 로고
    • Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
    • Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D: Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 2004, 305:1292-1295
    • (2004) Science , vol.305 , pp. 1292-1295
    • Cuervo, A.M.1    Stefanis, L.2    Fredenburg, R.3    Lansbury, P.T.4    Sulzer, D.5
  • 51
    • 0031787871 scopus 로고    scopus 로고
    • Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease
    • Conway KA, Harper JD, Lansbury PT: Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease. Nat Med 1998, 4:1318-1320
    • (1998) Nat Med , vol.4 , pp. 1318-1320
    • Conway, K.A.1    Harper, J.D.2    Lansbury, P.T.3
  • 52
    • 0034712918 scopus 로고    scopus 로고
    • Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation
    • Serpen LC, Berriman J, Jakes R, Goedert M, Crowther RA: Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation. Proc Natl Acad Sci USA 2000, 97:4897-4902
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4897-4902
    • Serpen, L.C.1    Berriman, J.2    Jakes, R.3    Goedert, M.4    Crowther, R.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.