-
1
-
-
2642514788
-
Alpha-synuclein: Normal function and role in neurodegenerative diseases
-
Norris EH, Giasson BI, Lee VMY: Alpha-synuclein: normal function and role in neurodegenerative diseases. Curr Top Dev Biol 2004, 60:17-54
-
(2004)
Curr Top Dev Biol
, vol.60
, pp. 17-54
-
-
Norris, E.H.1
Giasson, B.I.2
Lee, V.M.Y.3
-
2
-
-
27544507306
-
Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration
-
Chandra S, Gallardo G, Fernandez-Chacon R, Schluter OM, Sudhof TC: Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell 2005, 123:383-396
-
(2005)
Cell
, vol.123
, pp. 383-396
-
-
Chandra, S.1
Gallardo, G.2
Fernandez-Chacon, R.3
Schluter, O.M.4
Sudhof, T.C.5
-
3
-
-
23744443327
-
Nosology of Parkinson's disease: Looking for the way out of a quagmire
-
Forman MS, Lee VMY, Trojanowski JQ: Nosology of Parkinson's disease: looking for the way out of a quagmire. Neuron 2005, 47:479-482
-
(2005)
Neuron
, vol.47
, pp. 479-482
-
-
Forman, M.S.1
Lee, V.M.Y.2
Trojanowski, J.Q.3
-
4
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini MG, Schmidt ML, Lee VMY, Trojanowski JQ, Jakes R, Goedert M: Alpha-synuclein in Lewy bodies. Nature 1997, 388:839-840
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.Y.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
5
-
-
0038051345
-
Mitochondria, oxidative damage, and inflammation in Parkinson's disease
-
Beal MF: Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Ann NY Acad Sci 2003, 991:120-131
-
(2003)
Ann NY Acad Sci
, vol.991
, pp. 120-131
-
-
Beal, M.F.1
-
6
-
-
20744435383
-
Molecular pathophysiology of Parkinson's disease
-
Moore DJ, West AB, Dawson VL, Dawson TM: Molecular pathophysiology of Parkinson's disease. Annu Rev Neurosci 2005, 28:57-87
-
(2005)
Annu Rev Neurosci
, vol.28
, pp. 57-87
-
-
Moore, D.J.1
West, A.B.2
Dawson, V.L.3
Dawson, T.M.4
-
7
-
-
0023175904
-
Environmental and genetic factors in the etiology of Parkinson's disease
-
Barbeau PA, Cloutier T, Plasse L, Paris S: Environmental and genetic factors in the etiology of Parkinson's disease. Adv Neurol 1986, 45:299-306
-
(1986)
Adv Neurol
, vol.45
, pp. 299-306
-
-
Barbeau, P.A.1
Cloutier, T.2
Plasse, L.3
Paris, S.4
-
8
-
-
0023097950
-
Ecogenetics of Parkinson's disease: Prevalence and environmental aspects in rural areas
-
Barbeau A, Roy M, Bernier G, Campanella G, Paris S: Ecogenetics of Parkinson's disease: prevalence and environmental aspects in rural areas. Can J Neurol Sci 1987, 14:36-41
-
(1987)
Can J Neurol Sci
, vol.14
, pp. 36-41
-
-
Barbeau, A.1
Roy, M.2
Bernier, G.3
Campanella, G.4
Paris, S.5
-
9
-
-
0025230379
-
Parkinson's disease: A case-control study of occupational and environmental risk factors
-
Hertzman C, Weins M, Bowering D, Snow B, Calne D: Parkinson's disease: a case-control study of occupational and environmental risk factors. Am J Ind Med 1990, 17:349-355
-
(1990)
Am J Ind Med
, vol.17
, pp. 349-355
-
-
Hertzman, C.1
Weins, M.2
Bowering, D.3
Snow, B.4
Calne, D.5
-
10
-
-
0026524695
-
Exposure to well water and pesticides in Parkinson's disease: A case-control study in the Madrid area
-
Jimenez-Jimenez FJ, Mateo D, Gimenez-Roldman S: Exposure to well water and pesticides in Parkinson's disease: a case-control study in the Madrid area. Mov Disord 1992, 7:149-152
-
(1992)
Mov Disord
, vol.7
, pp. 149-152
-
-
Jimenez-Jimenez, F.J.1
Mateo, D.2
Gimenez-Roldman, S.3
-
11
-
-
0024535932
-
Environmental factors and Parkinson's disease: A case-control study in China
-
Tanner CM, Chen B, Wang W, Peng M, Liu Z, Liang X, Kao LC, Gilley DW, Goetz CG, Schoenberg BS: Environmental factors and Parkinson's disease: a case-control study in China. Neurology 1989, 39:660-664
-
(1989)
Neurology
, vol.39
, pp. 660-664
-
-
Tanner, C.M.1
Chen, B.2
Wang, W.3
Peng, M.4
Liu, Z.5
Liang, X.6
Kao, L.C.7
Gilley, D.W.8
Goetz, C.G.9
Schoenberg, B.S.10
-
12
-
-
0023882918
-
Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication
-
Ferraz HB, Bertolucci PH, Pereira JS, Lima JG, Andrade LA: Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication. Neurology 1988, 38:550-553
-
(1988)
Neurology
, vol.38
, pp. 550-553
-
-
Ferraz, H.B.1
Bertolucci, P.H.2
Pereira, J.S.3
Lima, J.G.4
Andrade, L.A.5
-
13
-
-
0028064283
-
Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate)
-
Meco G, Bonifati V, Vanacore N, Fabrizio E: Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate). Scand J Work Environ Health 1994, 20:301-305
-
(1994)
Scand J Work Environ Health
, vol.20
, pp. 301-305
-
-
Meco, G.1
Bonifati, V.2
Vanacore, N.3
Fabrizio, E.4
-
14
-
-
0037237927
-
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
-
Ischiropoulos H, Beckman JS: Oxidative stress and nitration in neurodegeneration: cause, effect, or association? J Clin Invest 2003, 111:163-169
-
(2003)
J Clin Invest
, vol.111
, pp. 163-169
-
-
Ischiropoulos, H.1
Beckman, J.S.2
-
15
-
-
0038334899
-
Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration
-
Manning-Bog AB, McCormack AL, Purisai MG, Bolin LM, Di Monte DA: Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration. J Neurosci 2003, 23:3095-3099
-
(2003)
J Neurosci
, vol.23
, pp. 3095-3099
-
-
Manning-Bog, A.B.1
McCormack, A.L.2
Purisai, M.G.3
Bolin, L.M.4
Di Monte, D.A.5
-
16
-
-
0027360342
-
Neonatal exposure to paraquat or MPTP induces permanent changes in striatum dopamine and behavior in adult mice
-
Fredriksson A, Fredriksson M, Eriksson P: Neonatal exposure to paraquat or MPTP induces permanent changes in striatum dopamine and behavior in adult mice. Toxicol Appl Pharmacol 1993, 122:258-264
-
(1993)
Toxicol Appl Pharmacol
, vol.122
, pp. 258-264
-
-
Fredriksson, A.1
Fredriksson, M.2
Eriksson, P.3
-
17
-
-
0029918777
-
Effects of paraquat on the substantia nigra of the Wistar rats: Neurochemical, histological, and behavioral studies
-
Liou HH, Chen RC, Tsai YF, Chen WP, Chang YC, Tsai MC: Effects of paraquat on the substantia nigra of the Wistar rats: neurochemical, histological, and behavioral studies. Toxicol Appl Pharmacol 1996, 137:34-41
-
(1996)
Toxicol Appl Pharmacol
, vol.137
, pp. 34-41
-
-
Liou, H.H.1
Chen, R.C.2
Tsai, Y.F.3
Chen, W.P.4
Chang, Y.C.5
Tsai, M.C.6
-
18
-
-
0037127197
-
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: Paraquat and alpha-synuclein
-
Manning-Bog AB, McCormack AL, Li J, Uversky VN, Fink AL, Di Monte DA: The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein. J Biol Chem 2002, 277:1641-1644
-
(2002)
J Biol Chem
, vol.277
, pp. 1641-1644
-
-
Manning-Bog, A.B.1
McCormack, A.L.2
Li, J.3
Uversky, V.N.4
Fink, A.L.5
Di Monte, D.A.6
-
19
-
-
0036075892
-
Environmental risk factors and Parkinson's disease: Selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat
-
McCormack AL, Thiruchelvam M, Manning-Bog AB, Thiffault C, Langston JW, Cory-Slechta DA, Di Monte DA: Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiol Dis 2002, 10:119-127
-
(2002)
Neurobiol Dis
, vol.10
, pp. 119-127
-
-
McCormack, A.L.1
Thiruchelvam, M.2
Manning-Bog, A.B.3
Thiffault, C.4
Langston, J.W.5
Cory-Slechta, D.A.6
Di Monte, D.A.7
-
20
-
-
0035816404
-
Pesticides directly accelerate the rate of alpha-synuclein fibril formation: A possible factor in Parkinson's disease
-
Uversky VN, Li J, Fink AL: Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease. FEBS Lett 2001, 500:105-108
-
(2001)
FEBS Lett
, vol.500
, pp. 105-108
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
22
-
-
0024829856
-
Acute exposure to maneb alters some behavioral functions in the mouse
-
Morato GS, Lemos T, Takahashi RN: Acute exposure to maneb alters some behavioral functions in the mouse. Neurotoxicol Teratol 1989, 11:421-425
-
(1989)
Neurotoxicol Teratol
, vol.11
, pp. 421-425
-
-
Morato, G.S.1
Lemos, T.2
Takahashi, R.N.3
-
23
-
-
0037265974
-
Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: A link through mitochondrial dysfunction
-
Zhang J, Fitsanakis VA, Gu G, Jing D, Ao M, Amarnath V, Montine TJ: Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: a link through mitochondrial dysfunction. J Neurochem 2003, 84:336-346
-
(2003)
J Neurochem
, vol.84
, pp. 336-346
-
-
Zhang, J.1
Fitsanakis, V.A.2
Gu, G.3
Jing, D.4
Ao, M.5
Amarnath, V.6
Montine, T.J.7
-
24
-
-
4444225471
-
Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: Relevance to Parkinson's disease
-
Zhou Y, Shie FS, Piccardo P, Montine TJ, Zhang J: Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: relevance to Parkinson's disease. Neuroscience 2004, 128:281-291
-
(2004)
Neuroscience
, vol.128
, pp. 281-291
-
-
Zhou, Y.1
Shie, F.S.2
Piccardo, P.3
Montine, T.J.4
Zhang, J.5
-
25
-
-
0034671469
-
The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: Implications for Parkinson's disease
-
Thiruchelvam M, Richfield EK, Baggs RB, Tank AW, Cory-Slechta DA: The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease. J Neurosci 2000, 20:9207-9214
-
(2000)
J Neurosci
, vol.20
, pp. 9207-9214
-
-
Thiruchelvam, M.1
Richfield, E.K.2
Baggs, R.B.3
Tank, A.W.4
Cory-Slechta, D.A.5
-
26
-
-
0036778511
-
Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype
-
Thiruchelvam M, Richfield EK, Goodman BM, Baggs RB, Cory-Slechta DA: Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype. Neurotoxicology 2002, 23:621-633
-
(2002)
Neurotoxicology
, vol.23
, pp. 621-633
-
-
Thiruchelvam, M.1
Richfield, E.K.2
Goodman, B.M.3
Baggs, R.B.4
Cory-Slechta, D.A.5
-
27
-
-
0042421940
-
Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype
-
Thiruchelvam M, McCormack A, Richfield EK, Baggs RB, Tank AW, Di Monte DA, Cory-Slechta DA: Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype. Eur J Neurosci 2003, 18:589-600
-
(2003)
Eur J Neurosci
, vol.18
, pp. 589-600
-
-
Thiruchelvam, M.1
McCormack, A.2
Richfield, E.K.3
Baggs, R.B.4
Tank, A.W.5
Di Monte, D.A.6
Cory-Slechta, D.A.7
-
28
-
-
0037118259
-
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VMY: Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 2002, 34:521-533
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.Y.6
-
29
-
-
0031941058
-
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies
-
Baba M, Nakajo S, Tu PH, Tomita T, Nakaya K, Lee VMY, Trojanowski JQ, Iwatsubo T: Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies. Am J Pathol 1998, 152:879-884
-
(1998)
Am J Pathol
, vol.152
, pp. 879-884
-
-
Baba, M.1
Nakajo, S.2
Tu, P.H.3
Tomita, T.4
Nakaya, K.5
Lee, V.M.Y.6
Trojanowski, J.Q.7
Iwatsubo, T.8
-
30
-
-
0036322266
-
Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases
-
Duda JE, Giasson BI, Mabon ME, Lee VMY, Trojanowski JQ: Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases. Ann Neurol 2002, 52:205-210
-
(2002)
Ann Neurol
, vol.52
, pp. 205-210
-
-
Duda, J.E.1
Giasson, B.I.2
Mabon, M.E.3
Lee, V.M.Y.4
Trojanowski, J.Q.5
-
31
-
-
0142177168
-
Age-dependent synuclein pathology following traumatic brain injury in mice
-
Uryu K, Giasson BI, Longhi L, Martinez D, Murray I, Conte V, Nakamura M, Saatman K, Talbot K, Horiguchi T, Mcintosh T, Lee VMY, Trojanowski JQ: Age-dependent synuclein pathology following traumatic brain injury in mice. Exp Neurol 2003, 184:214-224
-
(2003)
Exp Neurol
, vol.184
, pp. 214-224
-
-
Uryu, K.1
Giasson, B.I.2
Longhi, L.3
Martinez, D.4
Murray, I.5
Conte, V.6
Nakamura, M.7
Saatman, K.8
Talbot, K.9
Horiguchi, T.10
Mcintosh, T.11
Lee, V.M.Y.12
Trojanowski, J.Q.13
-
32
-
-
0023228210
-
Phosphate dependent and independent neurofilament epitopes in the axonal swellings of patients with motor neuron disease and controls
-
Schmidt ML, Carden MJ, Lee VMY, Trojanowski JQ: Phosphate dependent and independent neurofilament epitopes in the axonal swellings of patients with motor neuron disease and controls. Lab Invest 1987, 56:282-294
-
(1987)
Lab Invest
, vol.56
, pp. 282-294
-
-
Schmidt, M.L.1
Carden, M.J.2
Lee, V.M.Y.3
Trojanowski, J.Q.4
-
33
-
-
0024529404
-
Distribution of tau proteins in the normal human central and peripheral nervous system
-
Trojanowski JQ, Schuck T, Schmidt ML, Lee VMY: Distribution of tau proteins in the normal human central and peripheral nervous system. J Histochem Cytochem 1989, 37:209-215
-
(1989)
J Histochem Cytochem
, vol.37
, pp. 209-215
-
-
Trojanowski, J.Q.1
Schuck, T.2
Schmidt, M.L.3
Lee, V.M.Y.4
-
34
-
-
0033800039
-
Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy
-
Duda JE, Giasson BI, Gur TL, Montine TJ, Robertson D, Biaggioni I, Hurtig HI, Stern MB, Gollomp SM, Grossman M, Lee VMY, Trojanowski JQ: Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy. J Neuropathol Exp Neurol 2000, 59:830-841
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, pp. 830-841
-
-
Duda, J.E.1
Giasson, B.I.2
Gur, T.L.3
Montine, T.J.4
Robertson, D.5
Biaggioni, I.6
Hurtig, H.I.7
Stern, M.B.8
Gollomp, S.M.9
Grossman, M.10
Lee, V.M.Y.11
Trojanowski, J.Q.12
-
35
-
-
0033539664
-
Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein
-
Galvin JE, Uryu K, Lee VMY, Trojanowski JQ: Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein. Proc Natl Acad Sci USA 1999, 96:13450-13455
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13450-13455
-
-
Galvin, J.E.1
Uryu, K.2
Lee, V.M.Y.3
Trojanowski, J.Q.4
-
36
-
-
33746089104
-
Rat model of Parkinson's disease: Chronic central delivery of 1-methyl-4- phenylpyridinium (MPP(+))
-
Yazdani U, German DC, Liang CL, Manzino L, Sonsalla PK, Zeevalk GD: Rat model of Parkinson's disease: chronic central delivery of 1-methyl-4- phenylpyridinium (MPP(+)). Exp Neurol 2006, 200: 172-183
-
(2006)
Exp Neurol
, vol.200
, pp. 172-183
-
-
Yazdani, U.1
German, D.C.2
Liang, C.L.3
Manzino, L.4
Sonsalla, P.K.5
Zeevalk, G.D.6
-
37
-
-
0033583215
-
Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro
-
Giasson BI, Uryu K, Trojanowski JQ, Lee VMY: Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro. J Biol Chem 1999, 274:7619-7622
-
(1999)
J Biol Chem
, vol.274
, pp. 7619-7622
-
-
Giasson, B.I.1
Uryu, K.2
Trojanowski, J.Q.3
Lee, V.M.Y.4
-
38
-
-
0025942723
-
-
Hattori N, Tanaka M, Ozawa T, Mizuno Y: Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease. Ann Neurol 1991, 30:563-571
-
Hattori N, Tanaka M, Ozawa T, Mizuno Y: Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease. Ann Neurol 1991, 30:563-571
-
-
-
-
39
-
-
0028316759
-
Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease
-
Janetzky B, Hauck S, Youdim MB, Riederer P, Jellinger K, Pantucek F, Zochling R, Boissl KW, Reichmann H: Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease. Neurosci Lett 1994, 169:126-128
-
(1994)
Neurosci Lett
, vol.169
, pp. 126-128
-
-
Janetzky, B.1
Hauck, S.2
Youdim, M.B.3
Riederer, P.4
Jellinger, K.5
Pantucek, F.6
Zochling, R.7
Boissl, K.W.8
Reichmann, H.9
-
40
-
-
0026718086
-
Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease
-
Mann VM, Cooper JM, Krige D, Daniel SE, Schapira AH, Marsden CD: Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease. Brain 1992, 115:333-342
-
(1992)
Brain
, vol.115
, pp. 333-342
-
-
Mann, V.M.1
Cooper, J.M.2
Krige, D.3
Daniel, S.E.4
Schapira, A.H.5
Marsden, C.D.6
-
41
-
-
0025254401
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira AH, Cooper JM, Dexter D, Clark JB, Jenner P, Marsden CD: Mitochondrial complex I deficiency in Parkinson's disease. J Neurochem 1990, 54:823-827
-
(1990)
J Neurochem
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
42
-
-
0024334283
-
Mitochondrial function in Parkinson's disease
-
Bindoff LA, Birch-Machin M, Cartlidge NE, Parker Jr WD, Turnbull DM: Mitochondrial function in Parkinson's disease. Lancet 1989, 2:49
-
(1989)
Lancet
, vol.2
, pp. 49
-
-
Bindoff, L.A.1
Birch-Machin, M.2
Cartlidge, N.E.3
Parker Jr, W.D.4
Turnbull, D.M.5
-
43
-
-
17644426350
-
Role of oxidative damage in protein aggregation associated with Parkinson's disease and related disorders
-
Norris EH, Giasson BI: Role of oxidative damage in protein aggregation associated with Parkinson's disease and related disorders. Antioxid Redox Signal 2005, 7:672-684
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 672-684
-
-
Norris, E.H.1
Giasson, B.I.2
-
44
-
-
20044385568
-
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and alpha-synuclein
-
Fornai F, Schluter OM, Lenzi P, Gesi M, Ruffoli R, Ferrucci M, Lazzeri G, Busceti CL, Pontarelli F, Battaglia G, Pellegrini A, Nicoletti F, Ruggieri S, Paparelli A, Sudhof TC: Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein. Proc Natl Acad Sci USA 2005, 102:3413-3418
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3413-3418
-
-
Fornai, F.1
Schluter, O.M.2
Lenzi, P.3
Gesi, M.4
Ruffoli, R.5
Ferrucci, M.6
Lazzeri, G.7
Busceti, C.L.8
Pontarelli, F.9
Battaglia, G.10
Pellegrini, A.11
Nicoletti, F.12
Ruggieri, S.13
Paparelli, A.14
Sudhof, T.C.15
-
45
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, Greenamyre JT: Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 2000, 3:1301-1306
-
(2000)
Nat Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
46
-
-
33745612296
-
Intersecting pathways to neurodegeneration in Parkinson's disease: Effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system
-
Betarbet R, Canet-Aviles RM, Sherer TB, Mastroberardino PG, McLendon C, Kim JH, Lund S, Na HM, Taylor G, Bence NF, Kopito R, Seo BB, Yagi T, Yagi A, Klinefelter G, Cookson MR, Greenamyre JT: Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. Neurobiol Dis 2006, 22:404-420
-
(2006)
Neurobiol Dis
, vol.22
, pp. 404-420
-
-
Betarbet, R.1
Canet-Aviles, R.M.2
Sherer, T.B.3
Mastroberardino, P.G.4
McLendon, C.5
Kim, J.H.6
Lund, S.7
Na, H.M.8
Taylor, G.9
Bence, N.F.10
Kopito, R.11
Seo, B.B.12
Yagi, T.13
Yagi, A.14
Klinefelter, G.15
Cookson, M.R.16
Greenamyre, J.T.17
-
47
-
-
0037229425
-
Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation
-
Sherer TB, Kim JH, Betarbet R, Greenamyre JT: Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation. Exp Neurol 2003, 179:9-16
-
(2003)
Exp Neurol
, vol.179
, pp. 9-16
-
-
Sherer, T.B.1
Kim, J.H.2
Betarbet, R.3
Greenamyre, J.T.4
-
48
-
-
0344198025
-
Mechanism of toxicity in rotenone models of Parkinson's disease
-
Sherer TB, Betarbet R, Testa CM, Seo BB, Richardson JR, Kim JH, Miller GW, Yagi T, Matsuno-Yagi A, Greenamyre JT: Mechanism of toxicity in rotenone models of Parkinson's disease. J Neurosci 2003, 23:10756-10764
-
(2003)
J Neurosci
, vol.23
, pp. 10756-10764
-
-
Sherer, T.B.1
Betarbet, R.2
Testa, C.M.3
Seo, B.B.4
Richardson, J.R.5
Kim, J.H.6
Miller, G.W.7
Yagi, T.8
Matsuno-Yagi, A.9
Greenamyre, J.T.10
-
49
-
-
0033890821
-
Alpha-synuclein promotes mitochondrial deficit and oxidative stress
-
Hsu LJ, Sagara Y, Arroyo A, Rockenstein E, Sisk A, Mallory M, Wong J, Takenouchi T, Hashimoto M, Masliah E: Alpha-synuclein promotes mitochondrial deficit and oxidative stress. Am J Pathol 2000, 157:401-410
-
(2000)
Am J Pathol
, vol.157
, pp. 401-410
-
-
Hsu, L.J.1
Sagara, Y.2
Arroyo, A.3
Rockenstein, E.4
Sisk, A.5
Mallory, M.6
Wong, J.7
Takenouchi, T.8
Hashimoto, M.9
Masliah, E.10
-
50
-
-
4344659685
-
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
-
Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D: Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 2004, 305:1292-1295
-
(2004)
Science
, vol.305
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stefanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
51
-
-
0031787871
-
Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease
-
Conway KA, Harper JD, Lansbury PT: Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease. Nat Med 1998, 4:1318-1320
-
(1998)
Nat Med
, vol.4
, pp. 1318-1320
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury, P.T.3
-
52
-
-
0034712918
-
Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation
-
Serpen LC, Berriman J, Jakes R, Goedert M, Crowther RA: Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation. Proc Natl Acad Sci USA 2000, 97:4897-4902
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4897-4902
-
-
Serpen, L.C.1
Berriman, J.2
Jakes, R.3
Goedert, M.4
Crowther, R.A.5
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