-
1
-
-
69849111830
-
Viral RNA and DNA trigger common antiviral responses in mesangial cells
-
Allam R, Lichtnekert J, Moll AG, Taubitz A, Vielhauer V, Anders HJ: Viral RNA and DNA trigger common antiviral responses in mesangial cells. J Am Soc Nephrol 20: 1986-1996, 2009
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 1986-1996
-
-
Allam, R.1
Lichtnekert, J.2
Moll, A.G.3
Taubitz, A.4
Vielhauer, V.5
Anders, H.J.6
-
2
-
-
57149101578
-
Toll-like receptor 9 affects severity of IgA nephropathy
-
Suzuki H, Suzuki Y, Narita I, Aizawa M, Kihara M, Yamanaka T, Kanou T, Tsukaguchi H, Novak J, Horikoshi S, Tomino Y: Toll-like receptor 9 affects severity of IgA nephropathy. J Am Soc Nephrol 19: 2384-2395, 2008
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 2384-2395
-
-
Suzuki, H.1
Suzuki, Y.2
Narita, I.3
Aizawa, M.4
Kihara, M.5
Yamanaka, T.6
Kanou, T.7
Tsukaguchi, H.8
Novak, J.9
Horikoshi, S.10
Tomino, Y.11
-
3
-
-
44349126743
-
TLR4 links podocytes with the innate immune system to mediate glomerular injury
-
Banas MC, Banas B, Hudkins KL, Wietecha TA, Iyoda M, Bock E, Hauser P, Pippin JW, Shankland SJ, Smith KD, Stoelcker B, Liu G, Grone HJ, Kramer BK, Alpers CE: TLR4 links podocytes with the innate immune system to mediate glomerular injury. J Am Soc Nephrol 19: 704-713, 2008
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 704-713
-
-
Banas, M.C.1
Banas, B.2
Hudkins, K.L.3
Wietecha, T.A.4
Iyoda, M.5
Bock, E.6
Hauser, P.7
Pippin, J.W.8
Shankland, S.J.9
Smith, K.D.10
Stoelcker, B.11
Liu, G.12
Grone, H.J.13
Kramer, B.K.14
Alpers, C.E.15
-
4
-
-
44049103058
-
TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity
-
Zhang B, Ramesh G, Uematsu S, Akira S, Reeves WB: TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity. J Am Soc Nephrol 19: 923-932, 2008
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 923-932
-
-
Zhang, B.1
Ramesh, G.2
Uematsu, S.3
Akira, S.4
Reeves, W.B.5
-
5
-
-
77955644910
-
NF-kappaB in renal inflammation
-
Sanz AB, Sanchez-Nino MD, Ramos AM, Moreno JA, Santamaria B, Ruiz-Ortega M, Egido J, Ortiz A: NF-kappaB in renal inflammation. J Am Soc Nephrol 21: 1254-1262, 2010
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1254-1262
-
-
Sanz, A.B.1
Sanchez-Nino, M.D.2
Ramos, A.M.3
Moreno, J.A.4
Santamaria, B.5
Ruiz-Ortega, M.6
Egido, J.7
Ortiz, A.8
-
6
-
-
0032861082
-
Cell survival or death in renal tubular epithelium after ischemia- reperfusion injury
-
DOI 10.1046/j.1523-1755.1999.00701.x
-
Gobe G, Willgoss D, Hogg N, Schoch E, Endre Z: Cell survival or death in renal tubular epithelium after ischemia-reperfusion injury. Kidney Int 56: 1299-1304, 1999 (Pubitemid 29451235)
-
(1999)
Kidney International
, vol.56
, Issue.4
, pp. 1299-1304
-
-
Gobe, G.1
Willgoss, D.2
Hogg, N.3
Schoch, E.4
Endre, Z.5
-
7
-
-
4444261780
-
HMGB1 is an endogenous immune adjuvant released by necrotic cells
-
DOI 10.1038/sj.embor.7400205
-
Rovere-Querini P, Capobianco A, Scaffidi P, Valentinis B, Catalanotti F, Giazzon M, Dumitriu IE, Muller S, Iannacone M, Traversari C, Bianchi ME, Manfredi AA: HMGB1 is an endogenous immune adjuvant released by necrotic cells. EMBO Rep 5: 825-830, 2004 (Pubitemid 39199174)
-
(2004)
EMBO Reports
, vol.5
, Issue.8
, pp. 825-830
-
-
Rovere-Querini, P.1
Capobianco, A.2
Scaffidi, P.3
Valentinis, B.4
Catalanotti, F.5
Giazzon, M.6
Dumitriu, I.E.7
Muller, S.8
Iannacone, M.9
Traversari, C.10
Bianchi, M.E.11
Manfredi, A.A.12
-
8
-
-
0141998606
-
Molecular identification of a danger signal that alerts the immune system to dying cells
-
DOI 10.1038/nature01991
-
Shi Y, Evans JE, Rock KL: Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425: 516-521, 2003 (Pubitemid 37237047)
-
(2003)
Nature
, vol.425
, Issue.6957
, pp. 516-521
-
-
Shi, Y.1
Evans, J.E.2
Rock, K.L.3
-
9
-
-
0035451081
-
Genomic DNA released by dying cells induces the maturation of APCs
-
Ishii KJ, Suzuki K, Coban C, Takeshita F, Itoh Y, Matoba H, Kohn LD, Klinman DM: Genomic DNA released by dying cells induces the maturation of APCs. J Immunol 167: 2602-2607, 2001 (Pubitemid 32768888)
-
(2001)
Journal of Immunology
, vol.167
, Issue.5
, pp. 2602-2607
-
-
Ishii, K.J.1
Suzuki, K.2
Coban, C.3
Takeshita, F.4
Itoh, Y.5
Matoba, H.6
Kohn, L.D.7
Klinman, D.M.8
-
10
-
-
77955597328
-
Toll-like receptors and danger signaling in kidney injury
-
Anders HJ: Toll-like receptors and danger signaling in kidney injury. J Am Soc Nephrol 21: 1270-1274, 2010
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1270-1274
-
-
Anders, H.J.1
-
11
-
-
40449140937
-
The NLR Gene Family: A Standard Nomenclature
-
DOI 10.1016/j.immuni.2008.02.005, PII S1074761308000769
-
Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, Flavell RA, Girardin SE, Godzik A, Harton JA, Hoffman HM, Hugot JP, Inohara N, Mackenzie A, Maltais LJ, Nunez G, Ogura Y, Otten LA, Philpott D, Reed JC, Reith W, Schreiber S, Steimle V, Ward PA: The NLR gene family: A standard nomenclature. Immunity 28: 285-287, 2008 (Pubitemid 351350631)
-
(2008)
Immunity
, vol.28
, Issue.3
, pp. 285-287
-
-
Ting, J.P.-Y.1
Lovering, R.C.2
Alnemri, E.S.3
Bertin, J.4
Boss, J.M.5
Davis, B.K.6
Flavell, R.A.7
Girardin, S.E.8
Godzik, A.9
Harton, J.A.10
Hoffman, H.M.11
Hugot, J.-P.12
Inohara, N.13
MacKenzie, A.14
Maltais, L.J.15
Nunez, G.16
Ogura, Y.17
Otten, L.A.18
Philpott, D.19
Reed, J.C.20
Reith, W.21
Schreiber, S.22
Steimle, V.23
Ward, P.A.24
more..
-
12
-
-
77950362382
-
The inflammasomes
-
Schroder K, Tschopp J: The inflammasomes. Cell 140: 821-832, 2010
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
14
-
-
0038615855
-
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan
-
DOI 10.1126/science.1084677
-
Girardin SE, Boneca IG, Carneiro LA, Antignac A, Jehanno M, Viala J, Tedin K, Taha MK, Labigne A, Zahringer U, Coyle AJ, DiStefano PS, Bertin J, Sansonetti PJ, Philpott DJ: Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science 300: 1584-1587, 2003 (Pubitemid 36682892)
-
(2003)
Science
, vol.300
, Issue.5625
, pp. 1584-1587
-
-
Girardin, S.E.1
Boneca, I.G.2
Carneiro, L.A.M.3
Antignac, A.4
Jehanno, M.5
Viala, J.6
Tedin, K.7
Taha, M.-K.8
Labigne, A.9
Zahringer, U.10
Coyle, A.J.11
DiStefano, P.S.12
Bertin, J.13
Sansonetti, P.J.14
Philpott, D.J.15
-
15
-
-
0142180157
-
Peptidoglycan Molecular Requirements Allowing Detection by Nod1 and Nod2
-
DOI 10.1074/jbc.M307198200
-
Girardin SE, Travassos LH, Herve M, Blanot D, Boneca IG, Philpott DJ, Sansonetti PJ, Mengin-Lecreulx D: Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2. J Biol Chem 278: 41702-41708, 2003 (Pubitemid 37310428)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.43
, pp. 41702-41708
-
-
Girardin, S.E.1
Travassos, L.H.2
Herve, M.3
Blanot, D.4
Boneca, I.G.5
Philpott, D.J.6
Sansonetti, P.J.7
Mengin-Lecreulx, D.8
-
16
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing
-
DOI 10.1126/science.1103685
-
Maeda S, Hsu LC, Liu H, Bankston LA, Iimura M, Kagnoff MF, Eckmann L, Karin M: Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science 307: 734-738, 2005 (Pubitemid 40194645)
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.-C.2
Liu, H.3
Bankston, L.A.4
Iimura, M.5
Kagnoff, M.F.6
Eckmann, L.7
Karin, M.8
-
17
-
-
69249248197
-
Role of Nod2 in the development of Crohn's disease
-
Yamamoto S, Ma X: Role of Nod2 in the development of Crohn's disease. Microbes Infect 11: 912-918, 2009
-
(2009)
Microbes Infect
, vol.11
, pp. 912-918
-
-
Yamamoto, S.1
Ma, X.2
-
18
-
-
37549002511
-
The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock
-
Shao W, Yeretssian G, Doiron K, Hussain SN, Saleh M: The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. J Biol Chem 282: 36321-36329, 2007
-
(2007)
J Biol Chem
, vol.282
, pp. 36321-36329
-
-
Shao, W.1
Yeretssian, G.2
Doiron, K.3
Hussain, S.N.4
Saleh, M.5
-
19
-
-
2542457495
-
Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
-
DOI 10.1016/j.cell.2004.05.004, PII S0092867404004908
-
Martinon F, Tschopp J: Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases. Cell 117: 561-574, 2004 (Pubitemid 38692523)
-
(2004)
Cell
, vol.117
, Issue.5
, pp. 561-574
-
-
Martinon, F.1
Tschopp, J.2
-
20
-
-
77749304034
-
Critical functions of priming and lysosomal damage for NLRP3 activation
-
Hornung V, Latz E: Critical functions of priming and lysosomal damage for NLRP3 activation. Eur J Immunol 40: 620-623, 2010
-
(2010)
Eur J Immunol
, vol.40
, pp. 620-623
-
-
Hornung, V.1
Latz, E.2
-
21
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
DOI 10.1016/S1074-7613(04)00046-9, PII S1074761304000469
-
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J: NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle- Wells autoinflammatory disorder. Immunity 20: 319-325, 2004 (Pubitemid 38388233)
-
(2004)
Immunity
, vol.20
, Issue.3
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
22
-
-
0036671894
-
The Inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
DOI 10.1016/S1097-2765(02)00599-3
-
Martinon F, Burns K, Tschopp J: The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10: 417-426, 2002 (Pubitemid 35007355)
-
(2002)
Molecular Cell
, vol.10
, Issue.2
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
23
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
DOI 10.1038/sj.cdd.4402194, PII 4402194
-
Fernandes-Alnemri T, Wu J, Yu JW, Datta P, Miller B, Jankowski W, Rosenberg S, Zhang J, Alnemri ES: The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ 14: 1590-1604, 2007 (Pubitemid 47278845)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.9
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.-W.3
Datta, P.4
Miller, B.5
Jankowski, W.6
Rosenberg, S.7
Zhang, J.8
Alnemri, E.S.9
-
24
-
-
68149100523
-
NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways
-
Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP: NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. J Immunol 183: 2008-2015, 2009
-
(2009)
J Immunol
, vol.183
, pp. 2008-2015
-
-
Willingham, S.B.1
Allen, I.C.2
Bergstralh, D.T.3
Brickey, W.J.4
Huang, M.T.5
Taxman, D.J.6
Duncan, J.A.7
Ting, J.P.8
-
25
-
-
68149170478
-
Cutting edge: Necrosis activates the NLRP3 inflammasome
-
Li H, Ambade A, Re F: Cutting edge: Necrosis activates the NLRP3 inflammasome. J Immunol 183: 1528-1532, 2009
-
(2009)
J Immunol
, vol.183
, pp. 1528-1532
-
-
Li, H.1
Ambade, A.2
Re, F.3
-
26
-
-
33646072818
-
7 receptor: A key player in IL-1 processing and release
-
Ferrari D, Pizzirani C, Adinolfi E, Lemoli RM, Curti A, Idzko M, Panther E, Di Virgilio F: The P2X7 receptor: A key player in IL-1 processing and release. J Immunol 176: 3877-3883, 2006 (Pubitemid 44264361)
-
(2006)
Journal of Immunology
, vol.176
, Issue.7
, pp. 3877-3883
-
-
Ferrari, D.1
Pizzirani, C.2
Adinolfi, E.3
Lemoli, R.M.4
Curti, A.5
Idzko, M.6
Panther, E.7
Di, V.F.8
-
27
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
DOI 10.1038/sj.cdd.4402195, PII 4402195
-
Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J: Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 14: 1583-1589, 2007 (Pubitemid 47278844)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.9
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
28
-
-
40449097257
-
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
-
DOI 10.1038/nature06664, PII NATURE06664
-
Muruve DA, Petrilli V, Zaiss AK, White LR, Clark SA, Ross PJ, Parks RJ, Tschopp J: The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452: 103-107, 2008 (Pubitemid 351355095)
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 103-107
-
-
Muruve, D.A.1
Petrilli, V.2
Zaiss, A.K.3
White, L.R.4
Clark, S.A.5
Ross, P.J.6
Parks, R.J.7
Tschopp, J.8
-
29
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E: Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9: 847-856, 2008
-
(2008)
Nat Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
30
-
-
67449155853
-
Antiviral antibodies target adenovirus to phagolysosomes and amplify the innate immune response
-
Zaiss AK, Vilaysane A, Cotter MJ, Clark SA, Meijndert HC, Colarusso P, Yates RM, Petrilli V, Tschopp J, Muruve DA: Antiviral antibodies target adenovirus to phagolysosomes and amplify the innate immune response. J Immunol 182: 7058-7068, 2009
-
(2009)
J Immunol
, vol.182
, pp. 7058-7068
-
-
Zaiss, A.K.1
Vilaysane, A.2
Cotter, M.J.3
Clark, S.A.4
Meijndert, H.C.5
Colarusso, P.6
Yates, R.M.7
Petrilli, V.8
Tschopp, J.9
Muruve, D.A.10
-
31
-
-
58849160540
-
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
-
Sharp FA, Ruane D, Claass B, Creagh E, Harris J, Malyala P, Singh M, O'Hagan DT, Petrilli V, Tschopp J, O'Neill LA, Lavelle EC: Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome. Proc Natl Acad Sci U S A 106: 870-875, 2009
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 870-875
-
-
Sharp, F.A.1
Ruane, D.2
Claass, B.3
Creagh, E.4
Harris, J.5
Malyala, P.6
Singh, M.7
O'Hagan, D.T.8
Petrilli, V.9
Tschopp, J.10
O'Neill, L.A.11
Lavelle, E.C.12
-
32
-
-
70049101754
-
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases
-
Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier, M: Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. PLoS Pathog 5: e1000559, 2009
-
(2009)
PLoS Pathog
, vol.5
-
-
Shio, M.T.1
Eisenbarth, S.C.2
Savaria, M.3
Vinet, A.F.4
Bellemare, M.J.5
Harder, K.W.6
Sutterwala, F.S.7
Bohle, D.S.8
Descoteaux, A.9
Flavell, R.A.10
Olivier, M.11
-
33
-
-
34247118826
-
Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling
-
DOI 10.1016/j.immuni.2007.03.008, PII S1074761307002117
-
Kanneganti TD, Lamkanfi M, Kim YG, Chen G, Park JH, Franchi L, Vandenabeele P, Nunez G: Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity 26: 433-443, 2007 (Pubitemid 46603000)
-
(2007)
Immunity
, vol.26
, Issue.4
, pp. 433-443
-
-
Kanneganti, T.-D.1
Lamkanfi, M.2
Kim, Y.-G.3
Chen, G.4
Park, J.-H.5
Franchi, L.6
Vandenabeele, P.7
Nunez, G.8
-
34
-
-
70349334298
-
A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome
-
Munoz-Planillo R, Franchi L, Miller LS, Nunez G: A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J Immunol 183: 3942-3948, 2009
-
(2009)
J Immunol
, vol.183
, pp. 3942-3948
-
-
Munoz-Planillo, R.1
Franchi, L.2
Miller, L.S.3
Nunez, G.4
-
35
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J: Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 11: 136-140, 2010
-
(2010)
Nat Immunol
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
36
-
-
67349271142
-
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
-
Gross O, Poeck H, Bscheider M, Dostert C, Hannesschlager N, Endres S, Hartmann G, Tardivel A, Schweighoffer E, Tybulewicz V, Mocsai A, Tschopp J, Ruland J: Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 459: 433-436, 2009
-
(2009)
Nature
, vol.459
, pp. 433-436
-
-
Gross, O.1
Poeck, H.2
Bscheider, M.3
Dostert, C.4
Hannesschlager, N.5
Endres, S.6
Hartmann, G.7
Tardivel, A.8
Schweighoffer, E.9
Tybulewicz, V.10
Mocsai, A.11
Tschopp, J.12
Ruland, J.13
-
37
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E: Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol 183: 787-791, 2009
-
(2009)
J Immunol
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
MacDonald, K.5
Speert, D.6
Fernandes-Alnemri, T.7
Wu, J.8
Monks, B.G.9
Fitzgerald, K.A.10
Hornung, V.11
Latz, E.12
-
38
-
-
77649241461
-
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
Miao EA, Mao DP, Yudkovsky N, Bonneau R, Lorang CG, Warren SE, Leaf IA, Aderem A: Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci U S A 107: 3076-3080, 2010
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
Bonneau, R.4
Lorang, C.G.5
Warren, S.E.6
Leaf, I.A.7
Aderem, A.8
-
39
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
DOI 10.1038/ni1346, PII N1346
-
Franchi L, Am A, Body-Malapel M, Kanneganti TD, Ozoren N, Jagirdar R, Inohara N, Vandenabeele P, Bertin J, Coyle A, Grant EP, Nunez G: Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol 7: 576-582, 2006 (Pubitemid 43797338)
-
(2006)
Nature Immunology
, vol.7
, Issue.6
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.-D.4
Ozoren, N.5
Jagirdar, R.6
Inohara, N.7
Vandenabeele, P.8
Bertin, J.9
Coyle, A.10
Grant, E.P.11
Nunez, G.12
-
40
-
-
0035958867
-
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1
-
Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES: Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1. J Biol Chem 276: 28309-28313, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 28309-28313
-
-
Poyet, J.L.1
Srinivasula, S.M.2
Tnani, M.3
Razmara, M.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
41
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
DOI 10.1038/ng1724, PII NG1724
-
Boyden ED, Dietrich WF: Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet 38: 240-244, 2006 (Pubitemid 43177241)
-
(2006)
Nature Genetics
, vol.38
, Issue.2
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
42
-
-
60749136484
-
An orthogonal proteomicgenomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Burckstummer T, Baumann C, Bluml S, Dixit E, Durnberger G, Jahn H, Planyavsky M, Bilban M, Colinge J, Bennett KL, Superti- Furga G: An orthogonal proteomicgenomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 10: 266-272, 2009
-
(2009)
Nat Immunol
, vol.10
, pp. 266-272
-
-
Burckstummer, T.1
Baumann, C.2
Bluml, S.3
Dixit, E.4
Durnberger, G.5
Jahn, H.6
Planyavsky, M.7
Bilban, M.8
Colinge, J.9
Bennett, K.L.10
Superti- Furga, G.11
-
43
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES: AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458: 509-513, 2009
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
44
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA: AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458: 514-518, 2009
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
Latz, E.7
Fitzgerald, K.A.8
-
45
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, Idris A, Dunn JA, Kelly GM, Burnton CM, Hodgson S, Hardy LL, Garceau V, Sweet MJ, Ross IL, Hume DA, Stacey KJ: HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science 323: 1057-1060, 2009
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
Kelly, G.M.4
Burnton, C.M.5
Hodgson, S.6
Hardy, L.L.7
Garceau, V.8
Sweet, M.J.9
Ross, I.L.10
Hume, D.A.11
Stacey, K.J.12
-
46
-
-
77951263260
-
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
-
Fernandes-Alnemri T, Yu JW, Juliana C, Solorzano L, Kang S, Wu J, Datta P, Mc- Cormick M, Huang L, McDermott E, Eisenlohr L, Landel CP, Alnemri ES: The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol 11: 385-393, 2010
-
(2010)
Nat Immunol
, vol.11
, pp. 385-393
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Juliana, C.3
Solorzano, L.4
Kang, S.5
Wu, J.6
Datta, P.7
Mc- Cormick, M.8
Huang, L.9
McDermott, E.10
Eisenlohr, L.11
Landel, C.P.12
Alnemri, E.S.13
-
47
-
-
77951269392
-
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
-
Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, Waggoner L, Vanaja SK, Monks BG, Ganesan S, Latz E, Hornung V, Vogel SN, Szomolanyi-Tsuda E, Fitzgerald KA: The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol 11: 395-402, 2010
-
(2010)
Nat Immunol
, vol.11
, pp. 395-402
-
-
Rathinam, V.A.1
Jiang, Z.2
Waggoner, S.N.3
Sharma, S.4
Cole, L.E.5
Waggoner, L.6
Vanaja, S.K.7
Monks, B.G.8
Ganesan, S.9
Latz, E.10
Hornung, V.11
Vogel, S.N.12
Szomolanyi-Tsuda, E.13
Fitzgerald, K.A.14
-
48
-
-
77953305895
-
Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome
-
Kim S, Bauernfeind F, Ablasser A, Hartmann G, Fitzgerald KA, Latz E, Hornung V: Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome. Eur J Immunol 40: 1545-1551, 2010
-
(2010)
Eur J Immunol
, vol.40
, pp. 1545-1551
-
-
Kim, S.1
Bauernfeind, F.2
Ablasser, A.3
Hartmann, G.4
Fitzgerald, K.A.5
Latz, E.6
Hornung, V.7
-
49
-
-
77955294800
-
Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol
-
Sauer JD, Witte CE, Zemansky J, Hanson B, Lauer P, Portnoy DA: Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. Cell Host Microbe 7: 412-419, 2010
-
(2010)
Cell Host Microbe
, vol.7
, pp. 412-419
-
-
Sauer, J.D.1
Witte, C.E.2
Zemansky, J.3
Hanson, B.4
Lauer, P.5
Portnoy, D.A.6
-
50
-
-
0010464874
-
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing
-
Wang L, Manji GA, Grenier JM, Al-Garawi A, Merriam S, Lora JM, Geddes BJ, Briskin M, DiStefano PS, Bertin J: PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing. J Biol Chem 277: 29874-29880, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 29874-29880
-
-
Wang, L.1
Manji, G.A.2
Grenier, J.M.3
Al-Garawi, A.4
Merriam, S.5
Lora, J.M.6
Geddes, B.J.7
Briskin, M.8
DiStefano, P.S.9
Bertin, J.10
-
51
-
-
10644258637
-
PAN1/ NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages
-
DOI 10.1074/jbc.M406741200
-
Bruey JM, Bruey-Sedano N, Newman R, Chandler S, Stehlik C, Reed JC: PAN1/ NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages. J Biol Chem 279: 51897-51907, 2004 (Pubitemid 39656557)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.50
, pp. 51897-51907
-
-
Bruey, J.M.1
Bruey-Sedano, N.2
Newman, R.3
Chandler, S.4
Stehlik, C.5
Reed, J.C.6
-
52
-
-
0037792866
-
Interleukin-1-receptor antagonist in the Muckle-Wells syndrome
-
Hawkins PN, Lachmann HJ, McDermott MF: Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. N Engl J Med 348: 2583-2584, 2003
-
(2003)
N Engl J Med
, vol.348
, pp. 2583-2584
-
-
Hawkins, P.N.1
Lachmann, H.J.2
McDermott, M.F.3
-
53
-
-
49449094179
-
Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: Results from two sequential placebo-controlled studies
-
Hoffman HM, Throne ML, Amar NJ, Sebai M, Kivitz AJ, Kavanaugh A, Weinstein SP, Belomestnov P, Yancopoulos GD, Stahl N, Mellis SJ: Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: Results from two sequential placebo-controlled studies. Arthritis Rheum 58: 2443-2452, 2008
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2443-2452
-
-
Hoffman, H.M.1
Throne, M.L.2
Amar, N.J.3
Sebai, M.4
Kivitz, A.J.5
Kavanaugh, A.6
Weinstein, S.P.7
Belomestnov, P.8
Yancopoulos, G.D.9
Stahl, N.10
Mellis, S.J.11
-
54
-
-
67650736238
-
Horror autoinflammaticus: The molecular pathophysiology of autoinflammatory disease (*)
-
Masters SL, Simon A, Aksentijevich I, Kastner DL: Horror autoinflammaticus: The molecular pathophysiology of autoinflammatory disease (*). Annu Rev Immunol 27: 621-668, 2009
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 621-668
-
-
Masters, S.L.1
Simon, A.2
Aksentijevich, I.3
Kastner, D.L.4
-
55
-
-
66649121678
-
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist
-
Aksentijevich I, Masters SL, Ferguson PJ, Dancey P, Frenkel J, van Royen-Kerkhoff A, Laxer R, Tedgard U, Cowen EW, Pham TH, Booty M, Estes JD, Sandler NG, Plass N, Stone DL, Turner ML, Hill S, Butman JA, Schneider R, Babyn P, El-Shanti HI, Pope E, Barron K, Bing X, Laurence A, Lee CC, Chapelle D, Clarke GI, Ohson K, Nicholson M, Gadina M, Yang B, Korman BD, Gregersen PK, van Hagen PM, Hak AE, Huizing M, Rahman P, Douek DC, Remmers EF, Kastner DL, Goldbach-Mansky R: An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med 360: 2426-2437, 2009
-
(2009)
N Engl J Med
, vol.360
, pp. 2426-2437
-
-
Aksentijevich, I.1
Masters, S.L.2
Ferguson, P.J.3
Dancey, P.4
Frenkel, J.5
Van Royen-Kerkhoff, A.6
Laxer, R.7
Tedgard, U.8
Cowen, E.W.9
Pham, T.H.10
Booty, M.11
Estes, J.D.12
Sandler, N.G.13
Plass, N.14
Stone, D.L.15
Turner, M.L.16
Hill, S.17
Butman, J.A.18
Schneider, R.19
Babyn, P.20
El-Shanti, H.I.21
Pope, E.22
Barron, K.23
Bing, X.24
Laurence, A.25
Lee, C.C.26
Chapelle, D.27
Clarke, G.I.28
Ohson, K.29
Nicholson, M.30
Gadina, M.31
Yang, B.32
Korman, B.D.33
Gregersen, P.K.34
Van Hagen, P.M.35
Hak, A.E.36
Huizing, M.37
Rahman, P.38
Douek, D.C.39
Remmers, E.F.40
Kastner, D.L.41
Goldbach-Mansky, R.42
more..
-
56
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
DOI 10.1038/nature04516, PII N04516
-
Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J: Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440: 237-241, 2006 (Pubitemid 43372104)
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
57
-
-
70349402166
-
The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: Results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study
-
Terkeltaub R, Sundy JS, Schumacher HR, Murphy F, Bookbinder S, Biedermann S, Wu R, Mellis S, Radin A: The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: Results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study. Ann Rheum Dis 68: 1613-1617, 2009
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1613-1617
-
-
Terkeltaub, R.1
Sundy, J.S.2
Schumacher, H.R.3
Murphy, F.4
Bookbinder, S.5
Biedermann, S.6
Wu, R.7
Mellis, S.8
Radin, A.9
-
58
-
-
39749175570
-
Successful treatment of resistant pseudogout with anakinra
-
DOI 10.1002/art.23119
-
McGonagle D, Tan AL, Madden J, Emery P, McDermott MF: Successful treatment of resistant pseudogout with anakinra. Arthritis Rheum 58: 631-633, 2008 (Pubitemid 351294902)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.2
, pp. 631-633
-
-
McGonagle, D.1
Tan, A.L.2
Madden, J.3
Emery, P.4
McDermott, M.F.5
-
59
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
DOI 10.1126/science.1156995
-
Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J: Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320: 674-677, 2008 (Pubitemid 351928351)
-
(2008)
Science
, vol.320
, Issue.5876
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
60
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nunez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 464: 1357-1361, 2010
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
Abela, G.S.7
Franchi, L.8
Nunez, G.9
Schnurr, M.10
Espevik, T.11
Lien, E.12
Fitzgerald, K.A.13
Rock, K.L.14
Moore, K.J.15
Wright, S.D.16
Hornung, V.17
Latz, E.18
-
61
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT: The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol 9: 857-865, 2008
-
(2008)
Nat Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
62
-
-
68349157477
-
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
-
Dostert C, Guarda G, Romero JF, Menu P, Gross O, Tardivel A, Suva ML, Stehle JC, Kopf M, Stamenkovic I, Corradin G, Tschopp J: Malarial hemozoin is a Nalp3 inflammasome activating danger signal. PLoS One 4: e6510, 2009
-
(2009)
PLoS One
, vol.4
-
-
Dostert, C.1
Guarda, G.2
Romero, J.F.3
Menu, P.4
Gross, O.5
Tardivel, A.6
Suva, M.L.7
Stehle, J.C.8
Kopf, M.9
Stamenkovic, I.10
Corradin, G.11
Tschopp, J.12
-
63
-
-
73949118676
-
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
-
Iyer SS, Pulskens WP, Sadler JJ, Butter LM, Teske GJ, Ulland TK, Eisenbarth SC, Florquin S, Flavell RA, Leemans JC, Sutterwala FS: Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome. Proc Natl Acad Sci U S A 106: 20388-20393, 2009
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20388-20393
-
-
Iyer, S.S.1
Pulskens, W.P.2
Sadler, J.J.3
Butter, L.M.4
Teske, G.J.5
Ulland, T.K.6
Eisenbarth, S.C.7
Florquin, S.8
Flavell, R.A.9
Leemans, J.C.10
Sutterwala, F.S.11
-
64
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
DOI 10.1056/NEJMoa065213
-
Larsen CM, Faulenbach M, Vaag A, Volund A, Ehses JA, Seifert B, Mandrup-Poulsen T, Donath MY: Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med 356: 1517-1526, 2007 (Pubitemid 46588416)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.15
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
Volund, A.4
Ehses, J.A.5
Seifert, B.6
Mandrup-Poulsen, T.7
Donath, M.Y.8
-
65
-
-
77956103055
-
Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice
-
Lech M, Avila-Ferrufino A, Skuginna V, Susanti EH, Anders, HJ: Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice. Int Immunol 22: 717-728, 2010
-
(2010)
Int Immunol
, vol.22
, pp. 717-728
-
-
Lech, M.1
Avila-Ferrufino, A.2
Skuginna, V.3
Susanti, E.H.4
Anders, H.J.5
-
66
-
-
33646148726
-
Role of caspases on cell death, inflammation, and cell cycle in glycerol-induced acute renal failure
-
Homsi E, Janino P, de Faria JB: Role of caspases on cell death, inflammation, and cell cycle in glycerol-induced acute renal failure. Kidney Int 69: 1385-1392, 2006
-
(2006)
Kidney Int
, vol.69
, pp. 1385-1392
-
-
Homsi, E.1
Janino, P.2
De Faria, J.B.3
-
67
-
-
0036827012
-
Interleukin-1 beta stimulates human renal fibroblast proliferation and matrix protein production by means of a transforming growth factor-beta- dependent mechanism
-
DOI 10.1067/mlc.2002.128468
-
Vesey DA, Cheung C, Cuttle L, Endre Z, Gobe G, Johnson DW: Interleukin-1beta stimulates human renal fibroblast proliferation and matrix protein production by means of a transforming growth factor-beta- dependent mechanism. J Lab Clin Med 140: 342-350, 2002 (Pubitemid 35302027)
-
(2002)
Journal of Laboratory and Clinical Medicine
, vol.140
, Issue.5
, pp. 342-350
-
-
Vesey, D.A.1
Cheung, C.2
Cuttle, L.3
Endre, Z.4
Gobe, G.5
Johnson, D.W.6
-
68
-
-
33846965577
-
Effects of interleukin 18 on injury and activation of human proximal tubular epithelial cells
-
Liang D, Liu HF, Yao CW, Liu HY, Huang-Fu CM, Chen XW, Du SH: Effects of interleukin 18 on injury and activation of human proximal tubular epithelial cells. Nephrology (Carlton) 12: 53-61, 2007
-
(2007)
Nephrology (Carlton)
, vol.12
, pp. 53-61
-
-
Liang, D.1
Liu, H.F.2
Yao, C.W.3
Liu, H.Y.4
Huang-Fu, C.M.5
Chen, X.W.6
Du, S.H.7
-
69
-
-
35348940695
-
IL-18 is expressed in the intercalated cell of human kidney
-
DOI 10.1038/sj.ki.5002473, PII 5002473
-
Gauer S, Sichler O, Obermuller N, Holzmann Y, Kiss E, Sobkowiak E, Pfeilschifter J, Geiger H, Muhl H, Hauser IA: IL-18 is expressed in the intercalated cell of human kidney. Kidney Int 72: 1081-1087, 2007 (Pubitemid 47609039)
-
(2007)
Kidney International
, vol.72
, Issue.9
, pp. 1081-1087
-
-
Gauer, S.1
Sichler, O.2
Obermuller, N.3
Holzmann, Y.4
Kiss, E.5
Sobkowiak, E.6
Pfeilschifter, J.7
Geiger, H.8
Muhl, H.9
Hauser, I.A.10
-
70
-
-
0034939382
-
Elevated interleukin-18 levels in the urine of nephrotic patients
-
DOI 10.1159/000046017
-
Matsumoto K, Kanmatsuse K: Elevated interleukin- 18 levels in the urine of nephrotic patients. Nephron 88: 334-339, 2001 (Pubitemid 32695889)
-
(2001)
Nephron
, vol.88
, Issue.4
, pp. 334-339
-
-
Matsumoto, K.1
Kanmatsuse, K.2
-
71
-
-
0035081538
-
Augmented interleukin-18 production by peripheral blood monocytes in patients with minimal-change nephrotic syndrome
-
DOI 10.1159/000046214
-
Matsumoto K, Kanmatsuse K: Augmented interleukin-18 production by peripheral blood monocytes in patients with minimal-change nephrotic syndrome. Am J Nephrol 21: 20-27, 2001 (Pubitemid 32238609)
-
(2001)
American Journal of Nephrology
, vol.21
, Issue.1
, pp. 20-27
-
-
Matsumoto, K.1
Kanmatsuse, K.2
-
72
-
-
0038826504
-
Interleukin-18, interleukin-18 binding protein and impaired production of interferon-gamma in chronic renal failure
-
Lonnemann G, Novick D, Rubinstein M, Dinarello CA: Interleukin-18, interleukin-18 binding protein and impaired production of interferon-gamma in chronic renal failure. Clin Nephrol 60: 327-334, 2003 (Pubitemid 37407690)
-
(2003)
Clinical Nephrology
, vol.60
, Issue.5
, pp. 327-334
-
-
Lonnemann, G.1
Novick, D.2
Rubinstein, M.3
Dinarello, C.A.4
-
73
-
-
68949207806
-
IL-18 neutralization ameliorates obstruction-induced epithelial- mesenchymal transition and renal fibrosis
-
Bani-Hani AH, Leslie JA, Asanuma H, Dinarello CA, Campbell MT, Meldrum DR, Zhang H, Hile K, Meldrum KK: IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis. Kidney Int 76: 500-511, 2009
-
(2009)
Kidney Int
, vol.76
, pp. 500-511
-
-
Bani-Hani, A.H.1
Leslie, J.A.2
Asanuma, H.3
Dinarello, C.A.4
Campbell, M.T.5
Meldrum, D.R.6
Zhang, H.7
Hile, K.8
Meldrum, K.K.9
-
74
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
DOI 10.1038/nature04515, PII N04515
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M, Lee WP, Weinrauch Y, Monack DM, Dixit VM: Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440: 228-232, 2006 (Pubitemid 43372102)
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
75
-
-
67649831360
-
NLRP3/ cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury
-
Yamasaki K, Muto J, Taylor KR, Cogen AL, Audish D, Bertin J, Grant EP, Coyle AJ, Misaghi A, Hoffman HM, Gallo RL: NLRP3/ cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury. J Biol Chem 284: 12762-12771, 2009
-
(2009)
J Biol Chem
, vol.284
, pp. 12762-12771
-
-
Yamasaki, K.1
Muto, J.2
Taylor, K.R.3
Cogen, A.L.4
Audish, D.5
Bertin, J.6
Grant, E.P.7
Coyle, A.J.8
Misaghi, A.9
Hoffman, H.M.10
Gallo, R.L.11
-
76
-
-
69949175486
-
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors
-
Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Grone HJ, Schaefer L: Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem 284: 24035-24048, 2009
-
(2009)
J Biol Chem
, vol.284
, pp. 24035-24048
-
-
Babelova, A.1
Moreth, K.2
Tsalastra-Greul, W.3
Zeng-Brouwers, J.4
Eickelberg, O.5
Young, M.F.6
Bruckner, P.7
Pfeilschifter, J.8
Schaefer, R.M.9
Grone, H.J.10
Schaefer, L.11
-
77
-
-
67349203391
-
Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy
-
Chevalier RL, Forbes MS, Thornhill BA: Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy. Kidney Int 75: 1145-1152, 2009
-
(2009)
Kidney Int
, vol.75
, pp. 1145-1152
-
-
Chevalier, R.L.1
Forbes, M.S.2
Thornhill, B.A.3
-
78
-
-
33750201396
-
7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice
-
DOI 10.1038/sj.ki.5001804, PII 5001804
-
Goncalves RG, Gabrich L, Rosario A, Jr., Takiya CM, Ferreira ML, Chiarini LB, Persechini PM, Coutinho-Silva R, Leite M Jr: The role of purinergic P2X7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice. Kidney Int 70: 1599-1606, 2006 (Pubitemid 44606995)
-
(2006)
Kidney International
, vol.70
, Issue.9
, pp. 1599-1606
-
-
Goncalves, R.G.1
Gabrich, L.2
Rosario Jr., A.3
Takiya, C.M.4
Ferreira, M.L.L.5
Chiarini, L.B.6
Persechini, P.M.7
Coutinho-Silva, R.8
Leite Jr., M.9
-
79
-
-
77957887259
-
The NLRP3 inflammasome promotes renal inflammation and contributes to CKD
-
Vilaysane A, Chu J, Seamone ME, Wang W, Chin R, Hirota H, Li Y, Clark SA, Trpkov K, Tschopp J, Hemmelgarn BR, Beck PL, Muruve, DA: The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. J Am Soc Nephrol 21: 1732-1744, 2010
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1732-1744
-
-
Vilaysane, A.1
Chu, J.2
Seamone, M.E.3
Wang, W.4
Chin, R.5
Hirota, H.6
Li, Y.7
Clark, S.A.8
Trpkov, K.9
Tschopp, J.10
Hemmelgarn, B.R.11
Beck, P.L.12
Muruve, D.A.13
-
80
-
-
0034242625
-
Massive chemokine transcription in acute renal failure due to polymicrobial sepsis
-
Maier S, Emmanuilidis K, Entleutner M, Zantl N, Werner M, Pfeffer K, Heidecke CD: Massive chemokine transcription in acute renal failure due to polymicrobial sepsis. Shock 14: 187-192, 2000
-
(2000)
Shock
, vol.14
, pp. 187-192
-
-
Maier, S.1
Emmanuilidis, K.2
Entleutner, M.3
Zantl, N.4
Werner, M.5
Pfeffer, K.6
Heidecke, C.D.7
-
81
-
-
3242772187
-
Ischemic acute renal failure: An inflammatory disease?
-
Bonventre JV, Zuk A: Ischemic acute renal failure: An inflammatory disease? Kidney Int 66: 480-485, 2004
-
(2004)
Kidney Int
, vol.66
, pp. 480-485
-
-
Bonventre, J.V.1
Zuk, A.2
-
82
-
-
17644412421
-
Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis
-
DOI 10.1111/j.1523-1755.2004.66010.x
-
Faubel S, Ljubanovic D, Reznikov L, Somerset H, Dinarello CA, Edelstein CL: Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis. Kidney Int 66: 2202-2213, 2004 (Pubitemid 41115283)
-
(2004)
Kidney International
, vol.66
, Issue.6
, pp. 2202-2213
-
-
Faubel, S.1
Ljubanovic, D.2
Reznikov, L.3
Somerset, H.4
Dinarello, C.A.5
Edelstein, C.L.6
-
83
-
-
0036846099
-
lpr mice with autoimmune lupus nephritis
-
DOI 10.1002/art.10563
-
Faust J, Menke J, Kriegsmann J, Kelley VR, Mayet WJ, Galle PR, Schwarting A: Correlation of renal tubular epithelial cell-derived interleukin-18 up-regulation with disease activity in MRL-Faslpr mice with autoimmune lupus nephritis. Arthritis Rheum 46: 3083-3095, 2002 (Pubitemid 35315904)
-
(2002)
Arthritis and Rheumatism
, vol.46
, Issue.11
, pp. 3083-3095
-
-
Faust, J.1
Menke, J.2
Kriegsmann, J.3
Kelley, V.R.4
Mayet, W.J.5
Galle, P.R.6
Schwarting, A.7
-
84
-
-
0035015397
-
Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure
-
Melnikov VY, Ecder T, Fantuzzi G, Siegmund B, Lucia MS, Dinarello CA, Schrier RW, Edelstein CL: Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure. J Clin Invest 107: 1145-1152, 2001 (Pubitemid 32422911)
-
(2001)
Journal of Clinical Investigation
, vol.107
, Issue.9
, pp. 1145-1152
-
-
Melnikov, V.Y.1
Ecder, T.2
Fantuzzi, G.3
Siegmund, B.4
Lucia, M.S.5
Dinarello, C.A.6
Schrier, R.W.7
Edelstein, C.L.8
-
85
-
-
0036800759
-
Neutrophil-independent mechanisms of caspase-1- and IL-18-mediated ischemic acute tubular necrosis in mice
-
DOI 10.1172/JCI200215623
-
Melnikov VY, Faubel S, Siegmund B, Lucia MS, Ljubanovic D, Edelstein CL: Neutrophil-independent mechanisms of caspase-1- and IL-18- mediated ischemic acute tubular necrosis in mice. J Clin Invest 110: 1083-1091, 2002 (Pubitemid 35215889)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.8
, pp. 1083-1091
-
-
Melnikov, V.Y.1
Faubel, S.2
Siegmund, B.3
Scott, L.M.4
Ljubanovic, D.5
Edelstein, C.L.6
-
86
-
-
33644819168
-
Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit
-
DOI 10.1681/ASN.2005030236
-
Parikh CR, Abraham E, Ancukiewicz M, Edelstein CL: Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit. J Am Soc Nephrol 16: 3046-3052, 2005 (Pubitemid 44743502)
-
(2005)
Journal of the American Society of Nephrology
, vol.16
, Issue.10
, pp. 3046-3052
-
-
Parikh, C.R.1
Abraham, E.2
Ancukiewicz, M.3
Edelstein, C.L.4
-
87
-
-
33847376042
-
Reconstituted NALP1 Inflammasome Reveals Two-Step Mechanism of Caspase-1 Activation
-
DOI 10.1016/j.molcel.2007.01.032, PII S1097276507000780
-
Faustin B, Lartigue L, Bruey JM, Luciano F, Sergienko E, Bailly-Maitre B, Volkmann N, Hanein D, Rouiller I, Reed JC: Reconstituted NALP1 inflammasome reveals twostep mechanism of caspase-1 activation. Mol Cell 25: 713-724, 2007 (Pubitemid 46341921)
-
(2007)
Molecular Cell
, vol.25
, Issue.5
, pp. 713-724
-
-
Faustin, B.1
Lartigue, L.2
Bruey, J.-M.3
Luciano, F.4
Sergienko, E.5
Bailly-Maitre, B.6
Volkmann, N.7
Hanein, D.8
Rouiller, I.9
Reed, J.C.10
-
88
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
DOI 10.1038/nature04517, PII N04517
-
Kanneganti TD, Ozoren N, Body-Malapel M, Am A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, Akira S, Nunez G: Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/ Nalp3. Nature 440: 233-236, 2006 (Pubitemid 43372103)
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 233-236
-
-
Kanneganti, T.-D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.-H.5
Franchi, L.6
Whitfield, J.7
Barchet, W.8
Colonna, M.9
Vandenabeele, P.10
Bertin, J.11
Coyle, A.12
Grant, E.P.13
Akira, S.14
Nunez, G.15
-
89
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
-
Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschlager N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J: Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production. Nat Immunol 11: 63-69, 2010
-
(2010)
Nat Immunol
, vol.11
, pp. 63-69
-
-
Poeck, H.1
Bscheider, M.2
Gross, O.3
Finger, K.4
Roth, S.5
Rebsamen, M.6
Hannesschlager, N.7
Schlee, M.8
Rothenfusser, S.9
Barchet, W.10
Kato, H.11
Akira, S.12
Inoue, S.13
Endres, S.14
Peschel, C.15
Hartmann, G.16
Hornung, V.17
Ruland, J.18
-
90
-
-
70449448992
-
Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome
-
Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP: Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. J Immunol 182: 6460-6469, 2009
-
(2009)
J Immunol
, vol.182
, pp. 6460-6469
-
-
Duncan, J.A.1
Gao, X.2
Huang, M.T.3
O'Connor, B.P.4
Thomas, C.E.5
Willingham, S.B.6
Bergstralh, D.T.7
Jarvis, G.A.8
Sparling, P.F.9
Ting, J.P.10
-
91
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
DOI 10.1038/nature02664
-
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, Roose-Girma M, Erickson S, Dixit VM: Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430: 213-218, 2004 (Pubitemid 38902430)
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 213-218
-
-
Mariathasan, S.1
Hewton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
92
-
-
77749270973
-
Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NFkappa B activation but proceeds independently of TLR signaling and P2X7 receptor
-
Harder J, Franchi L, Munoz-Planillo R, Park JH, Reimer T, Nunez G: Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NFkappa B activation but proceeds independently of TLR signaling and P2X7 receptor. J Immunol 183: 5823-5829, 2009
-
(2009)
J Immunol
, vol.183
, pp. 5823-5829
-
-
Harder, J.1
Franchi, L.2
Munoz-Planillo, R.3
Park, J.H.4
Reimer, T.5
Nunez, G.6
-
93
-
-
33644985564
-
Critical role for NALP3/ CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala FS, Ogura Y, Szczepanik M, Lara-Tejero M, Lichtenberger GS, Grant EP, Bertin J, Coyle AJ, Galan JE, Askenase PW, Flavell RA: Critical role for NALP3/ CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 24: 317-327, 2006
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
Grant, E.P.6
Bertin, J.7
Coyle, A.J.8
Galan, J.E.9
Askenase, P.W.10
Flavell, R.A.11
-
94
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
DOI 10.1038/nature06939, PII NATURE06939
-
Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA: Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminum adjuvants. Nature 453: 1122-1126, 2008 (Pubitemid 351871731)
-
(2008)
Nature
, vol.453
, Issue.7198
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor Jr., W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
95
-
-
34547138176
-
The SPRY domain of pyrin, mutated in familial mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing
-
DOI 10.1038/sj.cdd.4402142, PII 4402142
-
Papin S, Cuenin S, Agostini L, Martinon F, Werner S, Beer HD, Grutter C, Grutter M, Tschopp J: The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing. Cell Death Differ 14: 1457-1466, 2007 (Pubitemid 47096500)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.8
, pp. 1457-1466
-
-
Papin, S.1
Cuenin, S.2
Agostini, L.3
Martinon, F.4
Werner, S.5
Beer, H.-D.6
Grutter, C.7
Grutter, M.8
Tschopp, J.9
-
96
-
-
34250623231
-
Treatment of familial mediterranean fever with anakinra
-
Belkhir R, Moulonguet-Doleris L, Hachulla E, Prinseau J, Baglin A, Hanslik T: Treatment of familial Mediterranean fever with anakinra. Ann Intern Med 146: 825-826, 2007 (Pubitemid 351650515)
-
(2007)
Annals of Internal Medicine
, vol.146
, Issue.11
, pp. 825-826
-
-
Belkhir, R.1
Moulonguet-Doleris, L.2
Hachulla, E.3
Prinseau, J.4
Baglin, A.5
Hanslik, T.6
-
97
-
-
0344823965
-
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
DOI 10.1073/pnas.2135380100
-
Shoham NG, Centola M, Mansfield E, Hull KM, Wood G, Wise CA, Kastner DL: Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syn- drome as disorders in the same pathway. Proc Natl Acad Sci U S A 100: 13501-13506, 2003 (Pubitemid 37444771)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.23
, pp. 13501-13506
-
-
Shoham, N.G.1
Centola, M.2
Mansfield, E.3
Hull, K.M.4
Wood, G.5
Wise, C.A.6
Kastner, D.L.7
-
98
-
-
14944380059
-
Anakinra for flares of pyogenic arthritis in PAPA syndrome [5]
-
DOI 10.1093/rheumatology/keh479
-
Dierselhuis MP, Frenkel J, Wulffraat NM, Boelens JJ: Anakinra for flares of pyogenic arthritis in PAPA syndrome. Rheumatology (Oxford) 44: 406-408, 2005 (Pubitemid 40361307)
-
(2005)
Rheumatology
, vol.44
, Issue.3
, pp. 406-408
-
-
Dierselhuis, M.P.1
Frenkel, J.2
Wulffraat, N.M.3
Boelens, J.J.4
-
99
-
-
33746876396
-
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition
-
DOI 10.1056/NEJMoa055137
-
Goldbach-Mansky R, Dailey NJ, Canna SW, Gelabert A, Jones J, Rubin BI, Kim HJ, Brewer C, Zalewski C, Wiggs E, Hill S, Turner ML, Karp BI, Aksentijevich I, Pucino F, Penzak SR, Haverkamp MH, Stein L, Adams BS, Moore TL, Fuhlbrigge RC, Shaham B, Jarvis JN, O'Neil K, Vehe RK, Beitz LO, Gardner G, Hannan WP, Warren RW, Horn W, Cole JL, Paul SM, Hawkins PN, Pham TH, Snyder C, Wesley RA, Hoffmann SC, Holland SM, Butman JA, Kastner DL: Neonatal- onset multisystem inflammatory disease responsive to interleukin-1beta inhibition. N Engl J Med 355: 581-592, 2006 (Pubitemid 44200651)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.6
, pp. 581-592
-
-
Goldbach-Mansky, R.1
Dailey, N.J.2
Canna, S.W.3
Gelabert, A.4
Jones, J.5
Rubin, B.I.6
Kim, H.J.7
Brewer, C.8
Zalewski, C.9
Wiggs, E.10
Hill, S.11
Turner, M.L.12
Karp, B.I.13
Aksentijevich, I.14
Pucino, F.15
Penzak, S.R.16
Haverkamp, M.H.17
Stein, L.18
Adams, B.S.19
Moore, T.L.20
Fuhlbrigge, R.C.21
Shaham, B.22
Jarvis, J.N.23
O'Neil, K.24
Vehe, R.K.25
Beitz, L.O.26
Gardner, G.27
Hannan, W.P.28
Warren, R.W.29
Horn, W.30
Cole, J.L.31
Paul, S.M.32
Hawkins, P.N.33
Tuyet, H.P.34
Snyder, C.35
Wesley, R.A.36
Hoffmann, S.C.37
Holland, S.M.38
Butman, J.A.39
Kastner, D.L.40
more..
-
100
-
-
33750489045
-
Treatment with anakinra in the hyperimmunoglobulinemia D/periodic fever syndrome
-
DOI 10.1007/s00296-006-0164-x
-
Rigante D, Ansuini V, Bertoni B, Pugliese AL, Avallone L, Federico G, Stabile A: Treatment with anakinra in the hyperimmunoglobulinemia D/periodic fever syndrome. Rheumatol Int 27: 97-100, 2006 (Pubitemid 44655757)
-
(2006)
Rheumatology International
, vol.27
, Issue.1
, pp. 97-100
-
-
Rigante, D.1
Ansuini, V.2
Bertoni, B.3
Pugliese, A.L.4
Avallone, L.5
Federico, G.6
Stabile, A.7
-
101
-
-
3843110981
-
Beneficial response to interleukin 1 receptor antagonist in traps [2]
-
PII S0002934304002554
-
Simon A, Bodar EJ, van der Hilst JC, van der Meer JW, Fiselier TJ, Cuppen MP, Drenth JP: Beneficial response to interleukin 1 receptor antagonist in traps. Am J Med 117: 208-210, 2004 (Pubitemid 39055877)
-
(2004)
American Journal of Medicine
, vol.117
, Issue.3
, pp. 208-210
-
-
Simon, A.1
Bodar, E.J.2
Van Der, H.J.C.H.3
Van Der, M.J.W.M.4
Fiselier, T.J.W.5
Cuppen, M.P.J.M.6
Drenth, J.P.H.7
-
102
-
-
40349113175
-
Mutations in NALP12 cause hereditary periodic fever syndromes
-
DOI 10.1073/pnas.0708616105
-
Jeru I, Duquesnoy P, Fernandes-Alnemri T, Cochet E, Yu JW, Lackmy-Port-Lis M, Grimprel E, Landman-Parker J, Hentgen V, Marlin S, McElreavey K, Sarkisian T, Grateau G, Alnemri ES, Amselem S: Mutations in NALP12 cause hereditary periodic fever syndromes. Proc Natl Acad Sci U S A 105: 1614-1619, 2008 (Pubitemid 351346563)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1614-1619
-
-
Jeru, I.1
Duquesnoy, P.2
Fernandes-Alnemri, T.3
Cochet, E.4
Yu, J.W.5
Lackmy-Port-Lis, M.6
Grimprel, E.7
Landman-Parker, J.8
Hentgen, V.9
Marlin, S.10
McElreavey, K.11
Sarkisian, T.12
Grateau, G.13
Alnemri, E.S.14
Amselem, S.15
-
103
-
-
40949104315
-
The future of the IL-1 receptor antagonist anakinra: From rheumatoid arthritis to adult-onset Still's disease and systemic-onset juvenile idiopathic arthritis
-
Kalliolias GD, Liossis SN: The future of the IL-1 receptor antagonist anakinra: From rheumatoid arthritis to adult-onset Still's disease and systemic-onset juvenile idiopathic arthritis. Expert Opin Investig Drugs 17: 349-359, 2008
-
(2008)
Expert Opin Investig Drugs
, vol.17
, pp. 349-359
-
-
Kalliolias, G.D.1
Liossis, S.N.2
-
104
-
-
49849103750
-
Resistant Behcet disease responsive to anakinra
-
Botsios C, Sfriso P, Furlan A, Punzi L, Dinarello CA: Resistant Behcet disease responsive to anakinra. Ann Intern Med 149: 284-286, 2008
-
(2008)
Ann Intern Med
, vol.149
, pp. 284-286
-
-
Botsios, C.1
Sfriso, P.2
Furlan, A.3
Punzi, L.4
Dinarello, C.A.5
-
105
-
-
33645298222
-
Refractory relapsing polychondritis: Rapid and sustained response in the treatment with an IL-1 receptor antagonist (anakinra)
-
Vounotrypidis P, Sakellariou GT, Zisopoulos D, Berberidis C: Refractory relapsing polychondritis: Rapid and sustained response in the treatment with an IL-1 receptor antagonist (anakinra). Rheumatology (Oxford) 45: 491-492, 2006
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 491-492
-
-
Vounotrypidis, P.1
Sakellariou, G.T.2
Zisopoulos, D.3
Berberidis, C.4
-
106
-
-
70350780280
-
Dysfunctional inflammasome in Schnitzler's syndrome
-
Pizzirani C, Falzoni S, Govoni M, La Corte R, Donadei S, Di Virgilio F, Trotta F, Lo Monaco A: Dysfunctional inflammasome in Schnitzler's syndrome. Rheumatology (Oxford) 48: 1304-1308, 2009
-
(2009)
Rheumatology (Oxford)
, vol.48
, pp. 1304-1308
-
-
Pizzirani, C.1
Falzoni, S.2
Govoni, M.3
La Corte, R.4
Donadei, S.5
Di Virgilio, F.6
Trotta, F.7
Lo Monaco, A.8
-
107
-
-
38749150377
-
Efficacy of anakinra, an IL1 receptor antagonist, in refractory Sweet syndrome
-
Delluc A, Limal N, Puechal X, Frances C, Piette JC, Cacoub P: Efficacy of anakinra, an IL1 receptor antagonist, in refractory Sweet syndrome. Ann Rheum Dis 67: 278-279, 2008
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 278-279
-
-
Delluc, A.1
Limal, N.2
Puechal, X.3
Frances, C.4
Piette, J.C.5
Cacoub, P.6
-
108
-
-
42749091765
-
Antisynthetase syndrome with refractory polyarthritis and fever successfully treated with the IL-1 receptor antagonist, anakinra: A case report
-
Furlan A, Botsios C, Ruffatti A, Todesco S, Punzi L: Antisynthetase syndrome with refractory polyarthritis and fever successfully treated with the IL-1 receptor antagonist, anakinra: A case report. Joint Bone Spine 75: 366-367, 2008
-
(2008)
Joint Bone Spine
, vol.75
, pp. 366-367
-
-
Furlan, A.1
Botsios, C.2
Ruffatti, A.3
Todesco, S.4
Punzi, L.5
-
109
-
-
16344374294
-
Preliminary results of safety and efficacy of the interleukin 1 receptor antagonist anakinra in patients with severe lupus arthritis
-
DOI 10.1136/ard.2004.025858
-
Ostendorf B, Iking-Konert C, Kurz K, Jung G, Sander O, Schneider M: Preliminary results of safety and efficacy of the interleukin 1 receptor antagonist anakinra in patients with severe lupus arthritis. Ann Rheum Dis 64: 630-633, 2005 (Pubitemid 40469097)
-
(2005)
Annals of the Rheumatic Diseases
, vol.64
, Issue.4
, pp. 630-633
-
-
Ostendorf, B.1
Iking-Konert, C.2
Kurz, K.3
Jung, G.4
Sander, O.5
Schneider, M.6
-
110
-
-
33751338504
-
An intronic variable number of tandem repeat polymorphisms of the cold-induced autoinflammatory syndrome 1 (CIAS1) gene modifies gene expression and is associated with essential hypertension
-
DOI 10.1038/sj.ejhg.5201698, PII 5201698
-
Omi T, Kumada M, Kamesaki T, Okuda H, Munkhtulga L, Yanagisawa Y, Utsumi N, Gotoh T, Hata A, Soma M, Umemura S, Ogihara T, Takahashi N, Tabara Y, Shimada K, Mano H, Kajii E, Miki T, Iwamoto S: An intronic variable number of tandem repeat polymorphisms of the cold-induced autoinflammatory syndrome 1 (CIAS1) gene modifies gene expression and is associated with essential hypertension. Eur J Hum Genet 14: 1295-1305, 2006 (Pubitemid 44804037)
-
(2006)
European Journal of Human Genetics
, vol.14
, Issue.12
, pp. 1295-1305
-
-
Omi, T.1
Kumada, M.2
Kamesaki, T.3
Okuda, H.4
Munkhtulga, L.5
Yanagisawa, Y.6
Utsumi, N.7
Gotoh, T.8
Hata, A.9
Soma, M.10
Umemura, S.11
Ogihara, T.12
Takahashi, N.13
Tabara, Y.14
Shimada, K.15
Mano, H.16
Kajii, E.17
Miki, T.18
Iwamoto, S.19
-
111
-
-
77951665667
-
Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction
-
Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study
-
Abbate A, Kontos MC, Grizzard JD, Biondi- Zoccai GG, Van Tassell BW, Robati R, Roach LM, Arena RA, Roberts CS, Varma A, Gelwix CC, Salloum FN, Hastillo A, Dinarello CA, Vetrovec, GW: Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study). Am J Cardiol 105: 1371-1377 e1, 2010
-
(2010)
Am J Cardiol
, vol.105
-
-
Abbate, A.1
Kontos, M.C.2
Grizzard, J.D.3
Biondi- Zoccai, G.G.4
Van Tassell, B.W.5
Robati, R.6
Roach, L.M.7
Arena, R.A.8
Roberts, C.S.9
Varma, A.10
Gelwix, C.C.11
Salloum, F.N.12
Hastillo, A.13
Dinarello, C.A.14
Vetrovec, G.W.15
-
112
-
-
67649117904
-
Systematic review and stratified meta-analysis of the efficacy of interleukin-1 receptor antagonist in animal models of stroke
-
Banwell V, Sena ES, Macleod MR: Systematic review and stratified meta-analysis of the efficacy of interleukin-1 receptor antagonist in animal models of stroke. J Stroke Cerebrovasc Dis 18: 269-276, 2009
-
(2009)
J Stroke Cerebrovasc Dis
, vol.18
, pp. 269-276
-
-
Banwell, V.1
Sena, E.S.2
Macleod, M.R.3
-
113
-
-
0034856386
-
IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury
-
Nesic O, Xu GY, McAdoo D, High KW, Hulsebosch C, Perez-Pol R: IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury. J Neurotrauma 18: 947-956, 2001 (Pubitemid 32852894)
-
(2001)
Journal of Neurotrauma
, vol.18
, Issue.9
, pp. 947-956
-
-
Nesic, O.1
Xu, G.-Y.2
McAdoo, D.3
High, K.W.4
Hulsebosch, C.5
Perez-Polo, R.6
-
114
-
-
77955475968
-
NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses
-
Gris D, Ye Z, Iocca HA, Wen H, Craven RR, Gris P, Huang M, Schneider M, Miller SD, Ting, JP: NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. J Immunol 185: 974-981, 2010
-
(2010)
J Immunol
, vol.185
, pp. 974-981
-
-
Gris, D.1
Ye, Z.2
Iocca, H.A.3
Wen, H.4
Craven, R.R.5
Gris, P.6
Huang, M.7
Schneider, M.8
Miller, S.D.9
Ting, J.P.10
-
115
-
-
34250792190
-
Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity
-
Watanabe H, Gaide O, Petrilli V, Martinon F, Contassot E, Roques S, Kummer JA, Tschopp J, French LE: Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity. J Invest Dermatol 127: 1956-1963, 2007
-
(2007)
J Invest Dermatol
, vol.127
, pp. 1956-1963
-
-
Watanabe, H.1
Gaide, O.2
Petrilli, V.3
Martinon, F.4
Contassot, E.5
Roques, S.6
Kummer, J.A.7
Tschopp, J.8
French, L.E.9
-
116
-
-
34250835251
-
The Inflammasome Mediates UVB-Induced Activation and Secretion of Interleukin-1beta by Keratinocytes
-
DOI 10.1016/j.cub.2007.05.074, PII S0960982207015084
-
Feldmeyer L, Keller M, Niklaus G, Hohl D, Werner S, Beer HD: The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes. Curr Biol 17: 1140-1145, 2007 (Pubitemid 46990888)
-
(2007)
Current Biology
, vol.17
, Issue.13
, pp. 1140-1145
-
-
Feldmeyer, L.1
Keller, M.2
Niklaus, G.3
Hohl, D.4
Werner, S.5
Beer, H.-D.6
-
117
-
-
58149141869
-
Reduced acetaminophen-induced liver injury in mice by genetic disruption of IL-1 receptor antagonist
-
Ishibe T, Kimura A, Ishida Y, Takayasu T, Hayashi T, Tsuneyama K, Matsushima K, Sakata I, Mukaida N, Kondo T: Reduced acetaminophen-induced liver injury in mice by genetic disruption of IL-1 receptor antagonist. Lab Invest 89: 68-79, 2009
-
(2009)
Lab Invest
, vol.89
, pp. 68-79
-
-
Ishibe, T.1
Kimura, A.2
Ishida, Y.3
Takayasu, T.4
Hayashi, T.5
Tsuneyama, K.6
Matsushima, K.7
Sakata, I.8
Mukaida, N.9
Kondo, T.10
-
118
-
-
77956128040
-
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
-
Bauer C, Duewell P, Mayer C, Lehr HA, Fitzgerald KA, Dauer M, Tschopp J, Endres S, Latz E, Schnurr, M: Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome. Gut 59: 1192-1199, 2010
-
(2010)
Gut
, vol.59
, pp. 1192-1199
-
-
Bauer, C.1
Duewell, P.2
Mayer, C.3
Lehr, H.A.4
Fitzgerald, K.A.5
Dauer, M.6
Tschopp, J.7
Endres, S.8
Latz, E.9
Schnurr, M.10
-
119
-
-
77950002937
-
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
-
Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD: The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 32: 379-391, 2010
-
(2010)
Immunity
, vol.32
, pp. 379-391
-
-
Zaki, M.H.1
Boyd, K.L.2
Vogel, P.3
Kastan, M.B.4
Lamkanfi, M.5
Kanneganti, T.D.6
-
120
-
-
1642350442
-
Contributions of IL-1beta and IL-1alpha to Crescentic Glomerulonephritis in Mice
-
DOI 10.1097/01.ASN.0000115704.86897.F4
-
Timoshanko JR, Kitching AR, Iwakura Y, Holdsworth SR, Tipping PG: Contributions of IL-1beta and IL-1alpha to crescentic glomerulonephritis in mice. J Am Soc Nephrol 15: 910-918, 2004 (Pubitemid 38375310)
-
(2004)
Journal of the American Society of Nephrology
, vol.15
, Issue.4
, pp. 910-918
-
-
Timoshanko, J.R.1
Kitching, A.R.2
Iwakura, Y.3
Holdsworth, S.R.4
Tipping, P.G.5
-
121
-
-
27744598420
-
IL-12p40 and IL-18 in crescentic glomerulonephritis: IL-12p40 is the key Th1-defining cytokine chain, whereas IL-18 promotes local inflammation and leukocyte recruitment
-
DOI 10.1681/ASN.2004121075
-
Kitching AR, Turner AL, Wilson GR, Semple T, Odobasic D, Timoshanko JR, O'Sullivan KM, Tipping PG, Takeda K, Akira S, Holdsworth SR: IL-12p40 and IL-18 in crescentic glomerulonephritis: IL-12p40 is the key Th1-defining cytokine chain, whereas IL-18 promotes local inflammation and leukocyte recruitment. J Am Soc Nephrol 16: 2023-2033, 2005 (Pubitemid 41716433)
-
(2005)
Journal of the American Society of Nephrology
, vol.16
, Issue.7
, pp. 2023-2033
-
-
Kitching, A.R.1
Turner, A.L.2
Wilson, G.R.A.3
Semple, T.4
Odobasic, D.5
Timoshanko, J.R.6
O'Sullivan, K.M.7
Tipping, P.G.8
Takeda, K.9
Akira, S.10
Holdsworth, S.R.11
-
122
-
-
6344279914
-
lpr mice
-
Kinoshita K, Yamagata T, Nozaki Y, Sugiyama M, Ikoma S, Funauchi M, Kanamaru A: Blockade of IL-18 receptor signaling delays the onset of autoimmune disease in MRL-Faslpr mice. J Immunol 173: 5312-5318, 2004 (Pubitemid 39387816)
-
(2004)
Journal of Immunology
, vol.173
, Issue.8
, pp. 5312-5318
-
-
Kinoshita, K.1
Yamagata, T.2
Nozaki, Y.3
Sugiyama, M.4
Ikoma, S.5
Funauchi, M.6
Kanamaru, A.7
-
123
-
-
0027197450
-
Immunoregulation of SLE-like disease by the IL-1 receptor: Disease modifying activity on BDF1 hybrid mice and MRL autoimmune mice
-
Schorlemmer HU, Kanzy EJ, Langner KD, Kurrle, R: Immunoregulation of SLE-like disease by the IL-1 receptor: Disease modifying activity on BDF1 hybrid mice and MRL autoimmune mice. Agents Actions 39 Spec No: C117-C120, 1993 (Pubitemid 23276745)
-
(1993)
Agents and Actions
, vol.39
, Issue.SPEC. ISS.
-
-
Schorlemmer, H.U.1
Kanzy, E.J.2
Langner, K.D.3
Kurrle, R.4
-
124
-
-
49949152618
-
Deletion of IL-18 receptor ameliorates renal injury in bovine serum albumin-induced glomerulonephritis
-
Sugiyama M, Kinoshita K, Kishimoto K, Shimazu H, Nozaki Y, Ikoma S, Funauchi M: Deletion of IL-18 receptor ameliorates renal injury in bovine serum albumin-induced glomerulonephritis. Clin Immunol 128: 103-108, 2008
-
(2008)
Clin Immunol
, vol.128
, pp. 103-108
-
-
Sugiyama, M.1
Kinoshita, K.2
Kishimoto, K.3
Shimazu, H.4
Nozaki, Y.5
Ikoma, S.6
Funauchi, M.7
-
125
-
-
0030681285
-
Interleukin-1 receptor antagonist modulates the progression of a spontaneously occurring IgA nephropathy in mice
-
Chen A, Sheu LF, Chou WY, Tsai SC, Chang DM, Liang SC, Lin FG, Lee WH: Interleukin-1 receptor antagonist modulates the progression of a spontaneously occurring IgA nephropathy in mice. Am J Kidney Dis 30: 693-702, 1997 (Pubitemid 27465365)
-
(1997)
American Journal of Kidney Diseases
, vol.30
, Issue.5
, pp. 693-702
-
-
Chen, A.1
Sheu, L.-F.2
Chou, W.-Y.3
Tsai, S.-C.4
Chang, D.-M.5
Liang, S.-C.6
Lin, F.-G.7
Lee, W.-H.8
-
126
-
-
0031944498
-
Role of IL-1 in renal ischemic reperfusion injury
-
Haq M, Norman J, Saba SR, Ramirez G, Rabb H: Role of IL-1 in renal ischemic reperfusion injury. J Am Soc Nephrol 9: 614-619, 1998
-
(1998)
J Am Soc Nephrol
, vol.9
, pp. 614-619
-
-
Haq, M.1
Norman, J.2
Saba, S.R.3
Ramirez, G.4
Rabb, H.5
-
127
-
-
57149102957
-
IL-18 contributes to renal damage after ischemia- reperfusion
-
Wu H, Craft ML, Wang P, Wyburn KR, Chen G, Ma J, Hambly B, Chadban SJ: IL-18 contributes to renal damage after ischemia- reperfusion. J Am Soc Nephrol 19: 2331-2341, 2008
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 2331-2341
-
-
Wu, H.1
Craft, M.L.2
Wang, P.3
Wyburn, K.R.4
Chen, G.5
Ma, J.6
Hambly, B.7
Chadban, S.J.8
-
128
-
-
0035164441
-
Genetically modified bone marrow-derived vehicle cells site specifically deliver an anti-inflammatory cytokine to inflamed interstitium of obstructive nephropathy
-
Yamagishi H, Yokoo T, Imasawa T, Mitarai T, Kawamura T, Utsunomiya Y: Genetically modified bone marrow-derived vehicle cells site specifically deliver an anti-inflammatory cytokine to inflamed interstitium of obstructive nephropathy. J Immunol 166: 609-616, 2001 (Pubitemid 32038484)
-
(2001)
Journal of Immunology
, vol.166
, Issue.1
, pp. 609-616
-
-
Yamagishi, H.1
Yokoo, T.2
Imasawa, T.3
Mitarai, T.4
Kawamura, T.5
Utsunomiya, Y.6
-
129
-
-
34247265509
-
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
-
DOI 10.1038/ni1459, PII NI1459
-
Mayor A, Martinon F, De Smedt T, Petrilli V, Tschopp J: A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses. Nat Immunol 8: 497-503, 2007 (Pubitemid 46605918)
-
(2007)
Nature Immunology
, vol.8
, Issue.5
, pp. 497-503
-
-
Mayor, A.1
Martinon, F.2
De Smedt, T.3
Petrilli, V.4
Tschopp, J.5
|