Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis

Kidney International

Volumn 66, Issue 6, 2004, Pages 2202-2213

  Faubel, Sarah ^b   Ljubanovic, Danica ^b   Reznikov, Leonid ^b   Somerset, Hilary ^b   Dinarello, Charles A ^b   Edelstein, Charles L ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Apoptosis; Caspase 1; Caspases; Cisplatin induced ARF; Inflammation; Necrosis

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CISPLATIN; CREATININE; INTERLEUKIN 1BETA CONVERTING ENZYME; ANTINEOPLASTIC AGENT; CASP3 PROTEIN, MOUSE; CASP8 PROTEIN, MOUSE; CASP9 PROTEIN, MOUSE; CASPASE;

ACUTE KIDNEY TUBULE NECROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVATION; ENZYME ACTIVITY; IMMUNOBLOTTING; KIDNEY; KIDNEY PARENCHYMA; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCORING SYSTEM; STATISTICAL SIGNIFICANCE; UREA NITROGEN BLOOD LEVEL; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; CYTOSOL; ENZYMOLOGY; GENETICS; KIDNEY TUBULE NECROSIS; METABOLISM; MOUSE MUTANT; NECROSIS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 1; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CISPLATIN; CYTOSOL; IMMUNOBLOTTING; KIDNEY; KIDNEY TUBULAR NECROSIS, ACUTE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NECROSIS; NEUTROPHILS;

EID: 17644412421     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2004.66010.x     Document Type: Article

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