Contributions of IL-1β and IL-1α to Crescentic Glomerulonephritis in Mice

Journal of the American Society of Nephrology

Volumn 15, Issue 4, 2004, Pages 910-918

  Timoshanko, Jennifer R ^a   Kitching, A Richard ^a   Iwakura, Yichiro ^b   Holdsworth, Stephen R ^a   Tipping, Peter G ^a  

^a MONASH MEDICAL CENTRE   (Australia)

^b THE UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; GLOBULIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FEMALE; GLOMERULONEPHRITIS; HUMORAL IMMUNITY; IMMUNOPATHOGENESIS; INFLAMMATORY CELL; MACROPHAGE; MALE; NONHUMAN; PARAMETER; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEINURIA; SHEEP; T LYMPHOCYTE; ANIMAL; C57BL MOUSE; IMMUNOLOGY; MOUSE; PATHOLOGY; PHYSIOLOGY; UROTHELIUM;

ANIMALS; GLOMERULONEPHRITIS; INTERLEUKIN-1; MICE; MICE, INBRED C57BL; SHEEP; UROTHELIUM;

EID: 1642350442     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ASN.0000115704.86897.F4     Document Type: Article

References (48)

1. Dinarello CA: Interleukin-1. Cytokine Growth Factor Rev 8: 253-265, 1997
2. Dinarello CA: Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int Rev Immunol 16: 457-499, 1998
3. Matsumoto K, Dowling J, Atkins RC: Production of interleukin I in glomerular cell cultures from patients with rapidly progressive crescentic glomerulonephritis. Am J Nephrol 8: 463-470, 1988
4. Tipping PG, Lowe MG, Holdsworth SR: Glomerular interleukin 1 production is dependent on macrophage infiltration in anti-GBM glomerulonephritis. Kidney Int 39: 103-110, 1991
5. Rosoff PM: IL-1 receptors: Structure and signals. Semin Immunol 2: 129-137, 1990
6. Sims JE, Giri JG, Dower SR: The two interleukin-1 receptors play different roles in IL-1 actions. Clin Immunol Immunopathol 72: 9-14, 1994
7. Sims JE, Gayle MA, Slack JL, Alderson MR, Bird TA, Giri JG, Colotta F, Re F, Mantovani A, Shanebeck K, et al: Interleukin 1 signalling occurs exclusively via the type I receptor. Proc Natl Acad Sci USA 90: 6155-6159, 1993
8. Burch RM, Mahan LC: Oligonucleotides antisense to the interleukin 1 receptor mRNA block the effects of interleukin 1 in cultured murine and human fibroblasts and in mice. J Clin Invest 88: 1190-1196, 1991
9. Rijneveld AW, Florquin S, Branger J, Speelman P, Van Deventer SJ, van der Poll T: TNF-α compensates for the impaired host defence of IL-1 type I receptor-deficient mice during pneumococcal pneumonia. J Immunol 167: 5240-5246, 2001
10. Fantuzzi G: Lessons from interleukin-deficient mice: The interleukin-1 system. Acta Physiol Scand 173: 5-9, 2001
11. Abbott F, Ryan JJ, Ceska M, Matsushima K, Sarraf CE, Rees AJ: Interleukin-1 beta stimulates human mesangial cells to synthesize and release interleukins-6 and -8. Kidney Int 40: 597-605, 1991
12. Francki A, Uciechowski P, Floege J, von der Ohe J, Resch K, Radeke HH: Autocrine growth regulation of human glomerular mesangial cells is primarily mediated by basic fibroblast growth factor. Am J Pathol 147: 1372-1382, 1995
13. Sterzel RB, Schulze-Lohoff E, Marx M: Cytokines and mesangial cells. Kidney Int Suppl 39: S26-S31, 1993
14. Shibuya K, Robinson D, Zonin F, Hartley SB, Macatonia SE, Somoza C, Hunter CA, Murphy KM, O'Garra A: IL-1α and TNF-α are required for IL-12-induced development of Th 1 cells producing high levels of IFN-γ in BALB/c but not C57BL/6 mice. J Immunol 160: 1708-1716, 1998
15. Robinson D, Shibuya K, Mui A, Zonin F, Murphy E, Sana T, Hartley SB, Menon S, Kastelein R, Bazan F, O'Garra A: IGIF does not drive Th1 development but synergizes with IL-12 for interferon-γ production and activates IRAK and NFκB. Immunity 7: 571-581, 1997
16. Boraschi D, Villa L, Volpini G, Bossu P, Censini S, Ghiara P, Scapigliat G, Nencioni L, Bartalini M, Matteucci G, et al: Differential activity of interleukin 1α and interleukin 1β in the stimulation of the immune response in vivo. Eur J Immunol 20: 317-321, 1990
17. Ji H, Pettit A, Ohmura K, Ortiz-Lopez A, Duchatelle V, Degott C, Gravallese E, Mathis D, Benoist C: Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis. J Exp Med 196: 77-85, 2002
18. Vervoordeldonk MJ, Tak PP: Cytokines in rheumatoid arthritis. Curr Rheumatol Rep 4: 208-217, 2002
19. Cannon JG, Tompkins RG, Gelfand JA, Michie HR, Stanford GG, van der Meer JW, Endres S, Lonnemann G, Corsetti J, Chernow B, et al: Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever. J Infect Dis 161: 79-84, 1990
20. Boswell JM, Yui MA, Endres S, Burt DW, Kelley VE: Novel and enhanced IL-1 gene expression in autoimmune mice with lupus. J Immunol 141: 118-124, 1988
21. Freeman BD, Buchman TG: Interleukin-1 receptor antagonist as therapy for inflammatory disorders. Expert Opin Biol Ther 1: 301-308, 2001
22. Jenkins DA, Wojtacha DR, Swan P, Fleming S, Cumming AD: Intrarenal localization of interleukin-1β mRNA in crescentic glomerulonephritis. Nephrol Dial Transplant 9: 1228-1233, 1994
23. Noronha IL, Kruger C, Andrassy K, Ritz E, Waldherr R: In situ production of TNF-α, IL-1β and IL-2R in ANCA-positive glomerulonephritis. Kidney Int 43: 682-692, 1993
24. Tang WW, Feng L, Vannice JL, Wilson CB: Interleukin-1 receptor antagonist ameliorates experimental anti-glomerular basement membrane antibody-associated glomerulonephritis. J Clin Invest 93: 273-279, 1994
25. Tomosugi NI, Cashman SJ, Hay H, Pusey CD, Evans DJ, Shaw A, Rees AJ: Modulation of antibody-mediated glomerular injury in vivo by bacterial lipopolysaccharide, tumor necrosis factor, and IL-1. J Immunol 142: 3083-3090, 1989
26. Karkar AM, Koshino Y, Cashman SJ, Dash AC, Bonnefoy J, Meager A, Rees AJ: Passive immunization against tumour necrosis factor-alpha (TNF-α) and IL-β protects from LPS enhancing glomerular injury in nephrotoxic nephritis in rats. Clin Exp Immunol 90: 312-318, 1992
27. Horai R, Asano M, Sudo K, Kanuka H, Suzuki M, Nishihara M, Takahashi M, Iwakura Y: Production of mice deficient in genes for interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 receptor antagonist shows that IL-1β is crucial in turpentine-induced fever development and glucocorticoid secretion. J Exp Med 187: 1463-1475, 1998
28. Labow M, Shuster D, Zetterstrom M, Nunes P, Terry R, Cullinan EB, Bartfai T, Solorzano C, Moldawer LL, Chizzonite R, McIntyre KW: Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice. J Immunol 159: 2452-2461, 1997
29. Timoshanko JR, Holdsworth SR, Kitching AR, Tipping PG: IFN-γ production by intrinsic renal cells and bone marrow-derived cells is required for full expression of crescentic glomerulonephritis in mice. J Immunol 168: 4135-4141, 2002
30. Timoshanko JR, Kitching AR, Holdsworth SR, Tipping PG: Interleukin-12 from intrinsic cells is an effector of renal injury in crescentic glomerulonephritis. J Am Soc Nephrol 12: 464-471, 2001
31. Huang XR, Holdsworth SR, Tipping PG: Evidence for delayed-type hypersensitivity mechanisms in glomerular crescent formation. Kidney Int 46: 69-78, 1994
32. Kitching AR, Holdsworth SR, Tipping PG: IFN-γ mediates crescent formation and cell-mediated immune injury in murine glomerulonephritis. J Am Soc Nephrol 10: 752-759, 1999
33. Huang XR, Tipping PG, Shuo L, Holdsworth SR: Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice. Kidney Int 51: 94-103, 1997
34. Kitching AR, Holdsworth SR, Tipping PG: Crescentic glomerulonephritis - a manifestation of a nephritogenic Th1 response? Histol Histopathol 15: 993-1003, 2000
35. Kitching AR, Tipping PG, Holdsworth SR: IL-12 directs severe renal injury, crescent formation and Th1 responses in murine glomerulonephritis. Eur J Immunol 29: 1-10, 1999
36. Tipping PG, Huang XR, Qi M, Van GY, Tang WW: Crescentic glomerulonephritis in CD4- and CD8-deficient mice. Requirement for CD4 but not CD8 cells. Am J Pathol 152: 1541-1548, 1998
37. Fantuzzi G, Zheng H, Faggioni R, Benigni F, Ghezzi P, Sipe JD, Shaw AR, Dinarello CA: Effect of endotoxin in IL-1β-deficient mice. J Immunol 157: 291-296, 1996
38. Shornick LP, De Togni P, Mariathasan S, Goellner J, Strauss-Schoenberger J, Karr RW, Ferguson TA, Chaplin DD: Mice deficient in IL-1β manifest impaired contact hypersensitivity to trinitrochlorobenzone. J Exp Med 183: 1427-1436, 1996
39. Li S, Holdsworth SR, Tipping PG: Antibody independent crescentic glomerulonephritis in mu chain deficient mice. Kidney Int 51: 672-678, 1997
40. Glaccum MB, Stocking KL, Charrier K, Smith JL, Willis CR, Maliszewski C, Livingston DJ, Peschon JJ, Morrissey PJ: Phenotypic and functional characterization of mice that lack the type I receptor for IL-1. J Immunol 159: 3364-3371, 1997
41. Satoskar AR, Okano M, Connaughton S, Raisanen-Sokolwski A, David JR, Labow M: Enhanced Th2-like responses in IL-1 type 1 receptor-deficient mice. Eur J Immunol 28: 2066-2074, 1998
42. Nakae S, Asano M, Horai R, Iwakura Y: Interleukin-1β, but not interleukin-1α, is required for T-cell-dependent antibody production. Immunology 104: 402-409, 2001
43. Nakae S, Naruse-Nakajima C, Sudo K, Horai R, Asano M, Iwakura Y: IL-1α, but not IL-1β, is required for contact-allergen-specific T cell activation during the sensitization phase in contact hypersensitivity. Int Immunol 13: 1471-1478, 2001
44. Saijo S, Asano M, Horai R, Yamamoto H, Iwakura Y: Suppression of autoimmune arthritis in interleukin-1-deficient mice in which T cell activation is impaired due to low levels of CD40 ligand and OX40 expression on T cells. Arthritis Rheum 46: 533-544, 2002
45. Nakae S, Komiyama Y, Yokoyama H, Nambu A, Umeda M, Iwase M, Homma I, Sudo K, Horai R, Asano M, Iwakura Y: IL-1 is required for allergen-specific T(h)2 cell activation and the development of airway hypersensitivity response. Int Immunol 15: 483-490, 2003
46. Nakae S, Asano M, Horai R, Sakaguchi N, Iwakura Y: IL-1 enhances T cell-dependent antibody production through induction of CD40 ligand and OX40 on T cells. J Immunol 167: 90-97, 2001
47. Lan HY, Nikolic-Paterson DJ, Zarama, M, Vannice JL, Atkins RC: Suppression of experimental crescentic glomerulonephritis by the interleukin-1 receptor antagonist. Kidney Int 43: 479-485, 1993
48. Lan HY, Nikolic-Paterson DJ, Mu W, Vannice JL, Atkins RC: Interleukin-1 receptor antagonist halts the progression of established crescentic glomerulonephritis in the rat. Kidney Int 47: 1303-1309, 1995