메뉴 건너뛰기




Volumn 6, Issue 2, 2011, Pages 125-147

Dietary chalcones with chemopreventive and chemotherapeutic potential

Author keywords

Chalcone derivatives; Chemoprevention; Chemotherapy; Diet

Indexed keywords

2 HYDROXYCHALCONE; 2' HYDROXY 4' METHOXYCHALCONE; 4 HYDROXYDERRICIN; 7,9,2',4' TETRAHYDROXY 8 ISOPENTENYL 5 METHOXYCHALCONE; ANTINEOPLASTIC AGENT; BROUSSOCHALCONE A; BUTEIN; CARDAMONIN; CHALCONE; CHALCONE DERIVATIVE; DESMETHYLXANTHOHUMOL; FLAVOKAVAIN A; FLAVOKAVAIN B; HYDROXYSAFFLOR YELLOW A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOBAVACHALCONE; ISOBUTRIN; ISOLESPEOL; ISOLIQUIRITIGENIN; ISOLIQUIRITIN; LICOCHALCONE A; LICOCHALCONE B; LICOCHALCONE D; LICOCHALCONE E; NARINGENIN CHALCONE; PHLORETIN; PHLORIZIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHOANGELOL; XANTHOHUMOL;

EID: 79956360137     PISSN: 15558932     EISSN: 18653499     Source Type: Journal    
DOI: 10.1007/s12263-011-0210-5     Document Type: Article
Times cited : (237)

References (195)
  • 1
    • 32644448421 scopus 로고    scopus 로고
    • Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects
    • DOI 10.1021/np058080d
    • T Akihisa H Tokuda D Hasegawa M Ukiya Y Kimura F Enjo T Suzuki H Nishino 2006 Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects J Nat Prod 69 38 42 16441065 1:CAS:528:DC%2BD28XjsFeruw%3D%3D (Pubitemid 43241751)
    • (2006) Journal of Natural Products , vol.69 , Issue.1 , pp. 38-42
    • Akihisa, T.1    Tokuda, H.2    Hasegawa, D.3    Ukiya, M.4    Kimura, Y.5    Enjo, F.6    Suzuki, T.7    Nishino, H.8
  • 2
    • 34547683652 scopus 로고    scopus 로고
    • Molecular pathways for cancer angioprevention
    • DOI 10.1158/1078-0432.CCR-07-0069
    • A Albini DM Noonan N Ferrari 2007 Molecular pathways for cancer angioprevention Clin Cancer Res 13 4320 4325 17671111 1:CAS:528: DC%2BD2sXotlGqs7k%3D (Pubitemid 47219694)
    • (2007) Clinical Cancer Research , vol.13 , Issue.15 , pp. 4320-4325
    • Albini, A.1    Noonan, D.M.2    Ferrari, N.3
  • 3
    • 28244456279 scopus 로고    scopus 로고
    • Tumor inflammatory angiogenesis and its chemoprevention
    • DOI 10.1158/0008-5472.CAN-05-3473
    • A Albini F Tosetti R Benelli DM Noonan 2005 Tumor inflammatory angiogenesis and its chemoprevention Cancer Res 65 10637 10641 16322203 1:CAS:528:DC%2BD2MXht1Gqu7bP (Pubitemid 41713327)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10637-10641
    • Albini, A.1    Tosetti, F.2    Benelli, R.3    Noonan, D.M.4
  • 4
    • 33645814383 scopus 로고    scopus 로고
    • Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-κB and Akt as targets
    • DOI 10.1096/fj.05-5128fje
    • A Albini R Dell'Eva R Vene N Ferrari DR Buhler DM Noonan G Fassina 2006 Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-kappaB and Akt as targets FASEB J 20 527 529 16403733 1:CAS:528: DC%2BD28Xis1ykurk%3D (Pubitemid 46671238)
    • (2006) FASEB Journal , vol.20 , Issue.3 , pp. 527-529
    • Albini, A.1    Dell'Eva, R.2    Vene, R.3    Ferrari, N.4    Buhler, D.R.5    Noonan, D.M.6    Fassina, G.7
  • 5
    • 4143070215 scopus 로고    scopus 로고
    • Role of nuclear factor-κB and heme oxygenase-1 in the mechanism of action of an anti-inflammatory chalcone derivative in RAW 264.7 cells
    • DOI 10.1038/sj.bjp.0705821
    • MJ Alcaraz AM Vicente A Araico JN Dominguez MC Terencio ML Ferrandiz 2004 Role of nuclear factor-kappaB and heme oxygenase-1 in the mechanism of action of an anti-inflammatory chalcone derivative in RAW 264.7 cells Br J Pharmacol 142 1191 1199 15249426 1:CAS:528:DC%2BD2cXmvFKqtL4%3D (Pubitemid 39093016)
    • (2004) British Journal of Pharmacology , vol.142 , Issue.7 , pp. 1191-1199
    • Alcaraz, M.J.1    Vicente, A.M.2    Araico, A.3    Dominguez, J.N.4    Terencio, M.C.5    Ferrandiz, M.L.6
  • 6
    • 7444272077 scopus 로고    scopus 로고
    • Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; inhibition of endothelial cell survival and proliferation by targeting phosphatidylinositol 3′-kinase activity
    • DOI 10.1158/0008-5472.CAN-03-3104
    • E Bagli M Stefaniotou L Morbidelli M Ziche K Psillas C Murphy T Fotsis 2004 Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; inhibition of endothelial cell survival and proliferation by targeting phosphatidylinositol 3′-kinase activity Cancer Res 64 7936 7946 15520200 1:CAS:528:DC%2BD2cXptFelsrc%3D (Pubitemid 39446927)
    • (2004) Cancer Research , vol.64 , Issue.21 , pp. 7936-7946
    • Bagli, E.1    Stefaniotou, M.2    Morbidelli, L.3    Ziche, M.4    Psillas, K.5    Murphy, C.6    Fotsis, T.7
  • 7
    • 77249174240 scopus 로고    scopus 로고
    • Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents
    • 20138527 1:CAS:528:DC%2BC3cXis1ajs7o%3D
    • BP Bandgar SS Gawande 2010 Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents Bioorg Med Chem 18 2060 2065 20138527 1:CAS:528:DC%2BC3cXis1ajs7o%3D
    • (2010) Bioorg Med Chem , vol.18 , pp. 2060-2065
    • Bandgar, B.P.1    Gawande, S.S.2
  • 8
    • 75149145989 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of simple methoxylated chalcones as anticancer, anti-inflammatory and antioxidant agents
    • 20064725 1:CAS:528:DC%2BC3cXhtlGisbY%3D
    • BP Bandgar SS Gawande RG Bodade JV Totre CN Khobragade 2010 Synthesis and biological evaluation of simple methoxylated chalcones as anticancer, anti-inflammatory and antioxidant agents Bioorg Med Chem 18 1364 1370 20064725 1:CAS:528:DC%2BC3cXhtlGisbY%3D
    • (2010) Bioorg Med Chem , vol.18 , pp. 1364-1370
    • Bandgar, B.P.1    Gawande, S.S.2    Bodade, R.G.3    Totre, J.V.4    Khobragade, C.N.5
  • 11
    • 0021244668 scopus 로고
    • (+)-Catechin inhibits the invasion of malignant fibrosarcoma cells into chick heart in vitro
    • ME Bracke RM Van Cauwenberge MM Mareel 1984 (+)-Catechin inhibits the invasion of malignant fibrosarcoma cells into chick heart in vitro Clin Exp Metastasis 2 161 170 6543696 1:CAS:528:DyaL2cXlsVeltLg%3D (Pubitemid 14099868)
    • (1984) Clinical and Experimental Metastasis , vol.2 , Issue.2 , pp. 161-170
    • Bracke, M.E.1    Van Cauwenberge, R.M.L.2    Mareel, M.M.3
  • 14
    • 14744278462 scopus 로고    scopus 로고
    • Small molecule antagonists of the MDM2 oncoprotein as anticancer agents
    • DOI 10.2174/1568009053332672
    • JK Buolamwini J Addo S Kamath S Patil D Mason M Ores 2005 Small molecule antagonists of the MDM2 oncoprotein as anticancer agents Curr Cancer Drug Targets 5 57 68 15720190 1:CAS:528:DC%2BD2MXhvVeqtL8%3D (Pubitemid 40326247)
    • (2005) Current Cancer Drug Targets , vol.5 , Issue.1 , pp. 57-68
    • Buolamwini, J.K.1    Addo, J.2    Kamath, S.3    Patil, S.4    Mason, D.5    Ores, M.6
  • 16
    • 0033118504 scopus 로고    scopus 로고
    • Angiogenesis inhibited by drinking tea
    • 10201368 1:CAS:528:DyaK1MXisFGmtLw%3D
    • Y Cao R Cao 1999 Angiogenesis inhibited by drinking tea Nature 398 381 10201368 1:CAS:528:DyaK1MXisFGmtLw%3D
    • (1999) Nature , vol.398 , pp. 381
    • Cao, Y.1    Cao, R.2
  • 18
    • 49049095526 scopus 로고    scopus 로고
    • Inhibitory action of hydroxysafflor yellow A on inflammatory signal transduction pathway related factors in rats with cerebral cortex ischemia
    • 18822957 1:CAS:528:DC%2BD1cXpslGrsrk%3D
    • TT Chen YJ Du XL Liu HB Zhu 2008 Inhibitory action of hydroxysafflor yellow A on inflammatory signal transduction pathway related factors in rats with cerebral cortex ischemia Yao Xue Xue Bao 43 570 575 18822957 1:CAS:528:DC%2BD1cXpslGrsrk%3D
    • (2008) Yao Xue Xue Bao , vol.43 , pp. 570-575
    • Chen, T.T.1    Du, Y.J.2    Liu, X.L.3    Zhu, H.B.4
  • 19
    • 0035871960 scopus 로고    scopus 로고
    • Broussochalcone A, a potent antioxidant and effective suppressor of inducible nitric oxide synthase in lipopolysaccharide-activated macrophages
    • DOI 10.1016/S0006-2952(01)00543-3, PII S0006295201005433
    • Z Cheng C Lin T Hwang C Teng 2001 Broussochalcone A, a potent antioxidant and effective suppressor of inducible nitric oxide synthase in lipopolysaccharide-activated macrophages Biochem Pharmacol 61 939 946 11286985 1:CAS:528:DC%2BD3MXisVWnsL8%3D (Pubitemid 32247382)
    • (2001) Biochemical Pharmacology , vol.61 , Issue.8 , pp. 939-946
    • Cheng, Z.-J.1    Lin, C.-N.2    Hwang, T.-L.3    Teng, C.-M.4
  • 21
    • 39949083016 scopus 로고    scopus 로고
    • Differential anti-inflammatory pathway by xanthohumol in IFN-gamma and LPS-activated macrophages
    • 18328448 1:CAS:528:DC%2BD1cXivFyktr4%3D
    • YC Cho HJ Kim YJ Kim KY Lee HJ Choi IS Lee BY Kang 2008 Differential anti-inflammatory pathway by xanthohumol in IFN-gamma and LPS-activated macrophages Int Immunopharmacol 8 567 573 18328448 1:CAS:528: DC%2BD1cXivFyktr4%3D
    • (2008) Int Immunopharmacol , vol.8 , pp. 567-573
    • Cho, Y.C.1    Kim, H.J.2    Kim, Y.J.3    Lee, K.Y.4    Choi, H.J.5    Lee, I.S.6    Kang, B.Y.7
  • 22
    • 77954478722 scopus 로고    scopus 로고
    • Prenylated chalcone from Sophora flavescens suppresses Th2 chemokine expression induced by cytokines via heme oxygenase-1 in human keratinocytes
    • 20512474 1:CAS:528:DC%2BC3cXmslWmsrg%3D
    • BM Choi GS Oh JW Lee JY Mok DK Kim SI Jeong SI Jang 2010 Prenylated chalcone from Sophora flavescens suppresses Th2 chemokine expression induced by cytokines via heme oxygenase-1 in human keratinocytes Arch Pharm Res 33 753 760 20512474 1:CAS:528:DC%2BC3cXmslWmsrg%3D
    • (2010) Arch Pharm Res , vol.33 , pp. 753-760
    • Choi, B.M.1    Oh, G.S.2    Lee, J.W.3    Mok, J.Y.4    Kim, D.K.5    Jeong, S.I.6    Jang, S.I.7
  • 23
    • 33846968137 scopus 로고    scopus 로고
    • Antioxidant properties of neohesperidin dihydrochalcone: Inhibition of hypochlorous acid-induced DNA strand breakage, protein degradation, and cell death
    • 17268074 1:CAS:528:DC%2BD2sXkvVSms78%3D
    • JM Choi BS Yoon SK Lee JK Hwang R Ryang 2007 Antioxidant properties of neohesperidin dihydrochalcone: inhibition of hypochlorous acid-induced DNA strand breakage, protein degradation, and cell death Biol Pharm Bull 30 324 330 17268074 1:CAS:528:DC%2BD2sXkvVSms78%3D
    • (2007) Biol Pharm Bull , vol.30 , pp. 324-330
    • Choi, J.M.1    Yoon, B.S.2    Lee, S.K.3    Hwang, J.K.4    Ryang, R.5
  • 24
    • 33645993864 scopus 로고    scopus 로고
    • Quinone reductase induction as a biomarker for cancer chemoprevention
    • 16562858 1:CAS:528:DC%2BD28XoslKhsA%3D%3D
    • M Cuendet CP Oteham RC Moon JM Pezzuto 2006 Quinone reductase induction as a biomarker for cancer chemoprevention J Nat Prod 69 460 463 16562858 1:CAS:528:DC%2BD28XoslKhsA%3D%3D
    • (2006) J Nat Prod , vol.69 , pp. 460-463
    • Cuendet, M.1    Oteham, C.P.2    Moon, R.C.3    Pezzuto, J.M.4
  • 27
    • 0032951716 scopus 로고    scopus 로고
    • p38 Mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes
    • DOI 10.1074/jbc.274.1.264
    • JL Dean M Brook AR Clark J Saklatvala 1999 p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes J Biol Chem 274 264 269 9867839 1:CAS:528:DyaK1MXjvVWksA%3D%3D (Pubitemid 29035058)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.1 , pp. 264-269
    • Dean, J.L.E.1    Brook, M.2    Clark, A.R.3    Saklatvala, J.4
  • 28
    • 33750500329 scopus 로고    scopus 로고
    • Anti-proliferative properties of prenylated flavonoids from hops (Humulus lupulus L.) in human prostate cancer cell lines
    • DOI 10.1016/j.phymed.2006.01.001, PII S0944711306000122
    • L Delmulle A Bellahcene W Dhooge F Comhaire F Roelens K Huvaere A Heyerick V Castronovo D De Keukeleire 2006 Anti-proliferative properties of prenylated flavonoids from hops (Humulus lupulus L.) in human prostate cancer cell lines Phytomedicine 13 732 734 16678392 1:CAS:528:DC%2BD2sXpsF2ksA%3D%3D (Pubitemid 44666399)
    • (2006) Phytomedicine , vol.13 , Issue.9-10 , pp. 732-734
    • Delmulle, L.1    Bellahcene, A.2    Dhooge, W.3    Comhaire, F.4    Roelens, F.5    Huvaere, K.6    Heyerick, A.7    Castronovo, V.8    De Keukeleire, D.9
  • 29
    • 0004580398 scopus 로고    scopus 로고
    • Flavonoids: Old and new aspects of a class of natural therapeutic drugs
    • DOI 10.1016/S0024-3205(99)00120-4, PII S0024320599001204
    • G Di Carlo N Mascolo AA Izzo F Capasso 1999 Flavonoids: old and new aspects of a class of natural therapeutic drugs Life Sci 65 337 353 10421421 1:CAS:528:DyaK1MXkt1ylur0%3D (Pubitemid 29325278)
    • (1999) Life Sciences , vol.65 , Issue.4 , pp. 337-353
    • Di Carlo, G.1    Mascolo, N.2    Izzo, A.A.3    Capasso, F.4
  • 31
    • 72049087235 scopus 로고    scopus 로고
    • Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: Synthesis and biological evaluation of antivascular activity
    • 19837593 1:CAS:528:DC%2BD1MXhtlCrsLbE
    • S Ducki D Rennison M Woo A Kendall JF Chabert AT McGown NJ Lawrence 2009 Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: synthesis and biological evaluation of antivascular activity Bioorg Med Chem 17 7698 7710 19837593 1:CAS:528:DC%2BD1MXhtlCrsLbE
    • (2009) Bioorg Med Chem , vol.17 , pp. 7698-7710
    • Ducki, S.1    Rennison, D.2    Woo, M.3    Kendall, A.4    Chabert, J.F.5    McGown, A.T.6    Lawrence, N.J.7
  • 32
    • 34047132303 scopus 로고    scopus 로고
    • Apigenin inhibits tumor angiogenesis through decreasing HIF-1α and VEGF expression
    • DOI 10.1093/carcin/bgl205
    • J Fang Q Zhou LZ Liu C Xia X Hu X Shi BH Jiang 2007 Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression Carcinogenesis 28 858 864 17071632 1:CAS:528:DC%2BD2sXjslOnsbk%3D (Pubitemid 46523341)
    • (2007) Carcinogenesis , vol.28 , Issue.4 , pp. 858-864
    • Fang, J.1    Zhou, Q.2    Liu, L.-Z.3    Xia, C.4    Hu, X.5    Shi, X.6    Jiang, B.-H.7
  • 33
    • 54349083136 scopus 로고    scopus 로고
    • Cytotoxic effects of new geranyl chalcone derivatives isolated from the leaves of Artocarpus communis in SW 872 human liposarcoma cells
    • 18767861 1:CAS:528:DC%2BD1cXhtVOhtLzN
    • SC Fang CL Hsu YS Yu GC Yen 2008 Cytotoxic effects of new geranyl chalcone derivatives isolated from the leaves of Artocarpus communis in SW 872 human liposarcoma cells J Agric Food Chem 56 8859 8868 18767861 1:CAS:528:DC%2BD1cXhtVOhtLzN
    • (2008) J Agric Food Chem , vol.56 , pp. 8859-8868
    • Fang, S.C.1    Hsu, C.L.2    Yu, Y.S.3    Yen, G.C.4
  • 34
    • 34250213433 scopus 로고    scopus 로고
    • Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer
    • 16969510 1:CAS:528:DC%2BD28XhtFSisrrK
    • HG Farina M Pomies DF Alonso DE Gomez 2006 Antitumor and antiangiogenic activity of soy isoflavone genistein in mouse models of melanoma and breast cancer Oncol Rep 16 885 891 16969510 1:CAS:528:DC%2BD28XhtFSisrrK
    • (2006) Oncol Rep , vol.16 , pp. 885-891
    • Farina, H.G.1    Pomies, M.2    Alonso, D.F.3    Gomez, D.E.4
  • 35
    • 0032805888 scopus 로고    scopus 로고
    • Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis
    • DOI 10.1038/11553
    • JL Ferrer JM Jez ME Bowman RA Dixon JP Noel 1999 Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis Nat Struct Biol 6 775 784 10426957 1:CAS:528:DyaK1MXltVShsLg%3D (Pubitemid 29360240)
    • (1999) Nature Structural Biology , vol.6 , Issue.8 , pp. 775-784
    • Ferrer, J.-L.1    Jez, J.M.2    Bowman, M.E.3    Dixon, R.A.4    Noel, J.P.5
  • 36
    • 33644821070 scopus 로고    scopus 로고
    • Inhibition of TNFα-induced activation of nuclear factor κB by kava (Piper methysticum) derivatives
    • DOI 10.1016/j.bcp.2005.12.032, PII S0006295206000049
    • F Folmer R Blasius F Morceau J Tabudravu M Dicato M Jaspars M Diederich 2006 Inhibition of TNFalpha-induced activation of nuclear factor kappaB by kava (Piper methysticum) derivatives Biochem Pharmacol 71 1206 1218 16464438 1:CAS:528:DC%2BD28Xit1ynu7s%3D (Pubitemid 43357901)
    • (2006) Biochemical Pharmacology , vol.71 , Issue.8 , pp. 1206-1218
    • Folmer, F.1    Blasius, R.2    Morceau, F.3    Tabudravu, J.4    Dicato, M.5    Jaspars, M.6    Diederich, M.7
  • 37
    • 33846842258 scopus 로고    scopus 로고
    • Chrysin inhibits expression of hypoxia-inducible factor 1-α through reducing hypoxia-inducible factor-1α stability and inhibiting its protein synthesis
    • DOI 10.1158/1535-7163.MCT-06-0526
    • B Fu J Xue Z Li X Shi BH Jiang J Fang 2007 Chrysin inhibits expression of hypoxia-inducible factor-1alpha through reducing hypoxia-inducible factor-1alpha stability and inhibiting its protein synthesis Mol Cancer Ther 6 220 226 17237281 1:CAS:528:DC%2BD2sXmsVamuw%3D%3D (Pubitemid 46206685)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.1 , pp. 220-226
    • Fu, B.1    Xue, J.2    Li, Z.3    Shi, X.4    Jiang, B.-H.5    Fang, J.6
  • 38
    • 4143140833 scopus 로고    scopus 로고
    • Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells
    • DOI 10.1016/j.bbrc.2004.07.094, PII S0006291X0401592X
    • Y Fu TC Hsieh J Guo J Kunicki MY Lee Z Darzynkiewicz JM Wu 2004 Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells Biochem Biophys Res Commun 322 263 270 15313200 1:CAS:528:DC%2BD2cXmslOhtb4%3D (Pubitemid 39093864)
    • (2004) Biochemical and Biophysical Research Communications , vol.322 , Issue.1 , pp. 263-270
    • Fu, Y.1    Hsieh, T.-C.2    Guo, J.3    Kunicki, J.4    Lee, M.Y.W.T.5    Darzynkiewicz, Z.6    Wu, J.M.7
  • 39
    • 70349337442 scopus 로고    scopus 로고
    • Licochalcone A potently inhibits tumor necrosis factor alpha-induced nuclear factor-kappaB activation through the direct inhibition of IkappaB kinase complex activation
    • 19592502 1:CAS:528:DC%2BD1MXht1eitrjO
    • M Funakoshi-Tago S Tanabe K Tago H Itoh T Mashino Y Sonoda T Kasahara 2009 Licochalcone A potently inhibits tumor necrosis factor alpha-induced nuclear factor-kappaB activation through the direct inhibition of IkappaB kinase complex activation Mol Pharmacol 76 745 753 19592502 1:CAS:528: DC%2BD1MXht1eitrjO
    • (2009) Mol Pharmacol , vol.76 , pp. 745-753
    • Funakoshi-Tago, M.1    Tanabe, S.2    Tago, K.3    Itoh, H.4    Mashino, T.5    Sonoda, Y.6    Kasahara, T.7
  • 40
    • 61649115375 scopus 로고    scopus 로고
    • Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway
    • 19291859 1:CAS:528:DC%2BD1MXjt1SnsLk%3D
    • J Furusawa M Funakoshi-Tago T Mashino K Tago H Inoue Y Sonoda T Kasahara 2009 Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway Int Immunopharmacol 9 499 507 19291859 1:CAS:528:DC%2BD1MXjt1SnsLk%3D
    • (2009) Int Immunopharmacol , vol.9 , pp. 499-507
    • Furusawa, J.1    Funakoshi-Tago, M.2    Mashino, T.3    Tago, K.4    Inoue, H.5    Sonoda, Y.6    Kasahara, T.7
  • 41
    • 60549108717 scopus 로고    scopus 로고
    • Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-kappaB p65 phosphorylation at serine 276
    • 19168128 1:CAS:528:DC%2BD1MXisFWjsb0%3D
    • J Furusawa M Funakoshi-Tago K Tago T Mashino H Inoue Y Sonoda T Kasahara 2009 Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-kappaB p65 phosphorylation at serine 276 Cell Signal 21 778 785 19168128 1:CAS:528:DC%2BD1MXisFWjsb0%3D
    • (2009) Cell Signal , vol.21 , pp. 778-785
    • Furusawa, J.1    Funakoshi-Tago, M.2    Tago, K.3    Mashino, T.4    Inoue, H.5    Sonoda, Y.6    Kasahara, T.7
  • 42
    • 79956361003 scopus 로고    scopus 로고
    • Isolation and potential cancer chemopreventive activities of phenolic compounds in beer
    • C Gerhauser 2002 Isolation and potential cancer chemopreventive activities of phenolic compounds in beer Phytochem Rev 1 11
    • (2002) Phytochem Rev , vol.1 , pp. 11
    • Gerhauser, C.1
  • 43
    • 26244450830 scopus 로고    scopus 로고
    • Beer constituents as potential cancer chemopreventive agents
    • DOI 10.1016/j.ejca.2005.04.012
    • C Gerhauser 2005 Beer constituents as potential cancer chemopreventive agents Eur J Cancer 41 1941 1954 15953717 (Pubitemid 41557680)
    • (2005) European Journal of Cancer , vol.41 , Issue.13 , pp. 1941-1954
    • Gerhauser, C.1
  • 45
    • 20144367578 scopus 로고    scopus 로고
    • Chalcones: An update on cytotoxic and chemoprotective properties
    • 15720256 1:STN:280:DC%2BD2M%2FptFemtA%3D%3D
    • ML Go X Wu XL Liu 2005 Chalcones: an update on cytotoxic and chemoprotective properties Curr Med Chem 12 481 499 15720256 1:STN:280:DC%2BD2M%2FptFemtA%3D%3D
    • (2005) Curr Med Chem , vol.12 , pp. 481-499
    • Go, M.L.1    Wu, X.2    Liu, X.L.3
  • 46
    • 34248139001 scopus 로고    scopus 로고
    • Suppression of VEGF-mediated autocrine and paracrine interactions between prostate cancer cells and vascular endothelial cells by soy isoflavones
    • DOI 10.1016/j.jnutbio.2006.08.006, PII S0955286306001872
    • Y Guo S Wang DR Hoot SK Clinton 2007 Suppression of VEGF-mediated autocrine and paracrine interactions between prostate cancer cells and vascular endothelial cells by soy isoflavones J Nutr Biochem 18 408 417 17142033 1:CAS:528:DC%2BD2sXlsFKntb0%3D (Pubitemid 46727041)
    • (2007) Journal of Nutritional Biochemistry , vol.18 , Issue.6 , pp. 408-417
    • Guo, Y.1    Wang, S.2    Hoot, D.R.3    Clinton, S.K.4
  • 48
    • 61949193344 scopus 로고    scopus 로고
    • Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells
    • 18952893 1:CAS:528:DC%2BD1MXivVaqtrw%3D
    • KB Harikumar AB Kunnumakkara KS Ahn P Anand S Krishnan S Guha BB Aggarwal 2009 Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells Blood 113 2003 2013 18952893 1:CAS:528:DC%2BD1MXivVaqtrw%3D
    • (2009) Blood , vol.113 , pp. 2003-2013
    • Harikumar, K.B.1    Kunnumakkara, A.B.2    Ahn, K.S.3    Anand, P.4    Krishnan, S.5    Guha, S.6    Aggarwal, B.B.7
  • 49
    • 1542541381 scopus 로고    scopus 로고
    • Specific inhibition of hypoxia-inducible factor (HIF)-1α activation and of vascular endothelial growth factor (VEGF) production by flavonoids
    • DOI 10.1248/bpb.26.1379
    • Y Hasebe K Egawa Y Yamazaki S Kunimoto Y Hirai Y Ida K Nose 2003 Specific inhibition of hypoxia-inducible factor (HIF)-1 alpha activation and of vascular endothelial growth factor (VEGF) production by flavonoids Biol Pharm Bull 26 1379 1383 14519939 1:CAS:528:DC%2BD3sXotlGrsrs%3D (Pubitemid 41685384)
    • (2003) Biological and Pharmaceutical Bulletin , vol.26 , Issue.10 , pp. 1379-1383
    • Hasebe, Y.1    Egawa, K.2    Yamazaki, Y.3    Kunimoto, S.4    Hirai, Y.5    Ida, Y.6    Nose, K.7
  • 50
    • 33748490486 scopus 로고    scopus 로고
    • The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFκB signalling pathways in monocytes/macrophages
    • DOI 10.1038/sj.bjp.0706856, PII 0706856
    • S Hatziieremia AI Gray VA Ferro A Paul R Plevin 2006 The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages Br J Pharmacol 149 188 198 16894344 1:CAS:528:DC%2BD28XptlSlsbY%3D (Pubitemid 44360100)
    • (2006) British Journal of Pharmacology , vol.149 , Issue.2 , pp. 188-198
    • Hatziieremia, S.1    Gray, A.I.2    Ferro, V.A.3    Paul, A.4    Plevin, R.5
  • 51
    • 0034027685 scopus 로고    scopus 로고
    • In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus
    • MC Henderson CL Miranda JF Stevens ML Deinzer DR Buhler 2000 In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus Xenobiotica 30 235 251 10752639 1:CAS:528:DC%2BD3cXjs1OmtLs%3D (Pubitemid 30179138)
    • (2000) Xenobiotica , vol.30 , Issue.3 , pp. 235-251
    • Henderson, M.C.1    Miranda, C.L.2    Stevens, J.F.3    Deinzer, M.L.4    Buhler, D.R.5
  • 52
    • 0035809312 scopus 로고    scopus 로고
    • Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: Roles of the nuclear factor of activated T cells and cyclooxygenase 2
    • DOI 10.1084/jem.193.5.607
    • GL Hernandez OV Volpert MA Iniguez E Lorenzo S Martinez-Martinez R Grau M Fresno JM Redondo 2001 Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2 J Exp Med 193 607 620 11238591 1:CAS:528:DC%2BD3MXhslGls70%3D (Pubitemid 32539557)
    • (2001) Journal of Experimental Medicine , vol.193 , Issue.5 , pp. 607-620
    • Hernandez, G.L.1    Volpert, O.V.2    Iniguez, M.A.3    Lorenzo, E.4    Martinez-Martinez, S.5    Grau, R.6    Fresno, M.7    Redondo, J.M.8
  • 53
    • 35148882512 scopus 로고    scopus 로고
    • Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages
    • DOI 10.1016/j.lfs.2007.09.001, PII S0024320507006479
    • S Hirai YI Kim T Goto MS Kang M Yoshimura A Obata R Yu T Kawada 2007 Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages Life Sci 81 1272 1279 17915259 1:CAS:528:DC%2BD2sXhtFGku77I (Pubitemid 47539506)
    • (2007) Life Sciences , vol.81 , Issue.16 , pp. 1272-1279
    • Hirai, S.1    Kim, Y.-I.2    Goto, T.3    Kang, M.-S.4    Yoshimura, M.5    Obata, A.6    Yu, R.7    Kawada, T.8
  • 54
    • 18844373926 scopus 로고    scopus 로고
    • Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cells
    • 15878356 1:CAS:528:DC%2BD2MXjvVOmtbw%3D
    • YL Hsu PL Kuo CC Lin 2005 Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cells Life Sci 77 279 292 15878356 1:CAS:528:DC%2BD2MXjvVOmtbw%3D
    • (2005) Life Sci , vol.77 , pp. 279-292
    • Hsu, Y.L.1    Kuo, P.L.2    Lin, C.C.3
  • 55
    • 3843137373 scopus 로고    scopus 로고
    • Isoliquiritigenin inhibits the proliferation and induces the apoptosis of human non-small cell lung cancer a549 cells
    • 15236626 1:CAS:528:DC%2BD2cXms1eju7Y%3D
    • YL Hsu PL Kuo LC Chiang CC Lin 2004 Isoliquiritigenin inhibits the proliferation and induces the apoptosis of human non-small cell lung cancer a549 cells Clin Exp Pharmacol Physiol 31 414 418 15236626 1:CAS:528: DC%2BD2cXms1eju7Y%3D
    • (2004) Clin Exp Pharmacol Physiol , vol.31 , pp. 414-418
    • Hsu, Y.L.1    Kuo, P.L.2    Chiang, L.C.3    Lin, C.C.4
  • 56
    • 14944347709 scopus 로고    scopus 로고
    • Isoliquiritigenin inhibits cell proliferation and induces apoptosis in human hepatoma cells
    • 15729620 1:CAS:528:DC%2BD2MXivFGlsL8%3D
    • YL Hsu PL Kuo LT Lin CC Lin 2005 Isoliquiritigenin inhibits cell proliferation and induces apoptosis in human hepatoma cells Planta Med 71 130 134 15729620 1:CAS:528:DC%2BD2MXivFGlsL8%3D
    • (2005) Planta Med , vol.71 , pp. 130-134
    • Hsu, Y.L.1    Kuo, P.L.2    Lin, L.T.3    Lin, C.C.4
  • 57
    • 33645218036 scopus 로고    scopus 로고
    • Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis
    • 16307839 1:CAS:528:DC%2BD28XivVGktLg%3D
    • YL Hsu PL Kuo WS Tzeng CC Lin 2006 Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis Food Chem Toxicol 44 704 713 16307839 1:CAS:528:DC%2BD28XivVGktLg%3D
    • (2006) Food Chem Toxicol , vol.44 , pp. 704-713
    • Hsu, Y.L.1    Kuo, P.L.2    Tzeng, W.S.3    Lin, C.C.4
  • 58
    • 68149160590 scopus 로고    scopus 로고
    • Shallot and licorice constituent isoliquiritigenin arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and initiation of the mitochondrial system in human cervical carcinoma HeLa cells
    • 19536869 1:CAS:528:DC%2BD1MXpsV2lurw%3D
    • YL Hsu CC Chia PJ Chen SE Huang SC Huang PL Kuo 2009 Shallot and licorice constituent isoliquiritigenin arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and initiation of the mitochondrial system in human cervical carcinoma HeLa cells Mol Nutr Food Res 53 826 835 19536869 1:CAS:528:DC%2BD1MXpsV2lurw%3D
    • (2009) Mol Nutr Food Res , vol.53 , pp. 826-835
    • Hsu, Y.L.1    Chia, C.C.2    Chen, P.J.3    Huang, S.E.4    Huang, S.C.5    Kuo, P.L.6
  • 59
    • 1842577637 scopus 로고    scopus 로고
    • CIP1/WAF1 expression in human lung cancer cells by isoliquiritigenin
    • DOI 10.1016/j.canlet.2003.10.023, PII S0304383503007493
    • T Ii Y Satomi D Katoh J Shimada M Baba T Okuyama H Nishino N Kitamura 2004 Induction of cell cycle arrest and p21(CIP1/WAF1) expression in human lung cancer cells by isoliquiritigenin Cancer Lett 207 27 35 15050731 1:CAS:528:DC%2BD2cXisF2gsrs%3D (Pubitemid 38429884)
    • (2004) Cancer Letters , vol.207 , Issue.1 , pp. 27-35
    • Ii, T.1    Satomi, Y.2    Katoh, D.3    Shimada, J.4    Baba, M.5    Okuyama, T.6    Nishino, H.7    Kitamura, N.8
  • 60
    • 33748758968 scopus 로고    scopus 로고
    • Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-κB nuclear translocation and Iκ-B phosphorylation in RAW 264.7 macrophage cells
    • DOI 10.1016/j.molimm.2006.04.025, PII S0161589006001702
    • DA Israf TA Khaizurin A Syahida NH Lajis S Khozirah 2007 Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-kappaB nuclear translocation and Ikappa-B phosphorylation in RAW 264.7 macrophage cells Mol Immunol 44 673 679 16777230 1:CAS:528:DC%2BD28XpvVOhtb0%3D (Pubitemid 44415023)
    • (2007) Molecular Immunology , vol.44 , Issue.5 , pp. 673-679
    • Israf, D.A.1    Khaizurin, T.A.2    Syahida, A.3    Lajis, N.H.4    Khozirah, S.5
  • 61
    • 0037221332 scopus 로고    scopus 로고
    • Inhibition of angiogenesis at endothelial cell level
    • DOI 10.1002/jemt.10247
    • A Jekunen K Kairemo 2003 Inhibition of angiogenesis at endothelial cell level Microsc Res Tech 60 85 97 12500265 (Pubitemid 36055237)
    • (2003) Microscopy Research and Technique , vol.60 , Issue.1 , pp. 85-97
    • Jekunen, A.1    Kairemo, K.2
  • 62
    • 36849052911 scopus 로고    scopus 로고
    • Structural requirements of 2′,4′,6′- tris(methoxymethoxy) chalcone derivatives for anti-inflammatory activity: The importance of a 2′-hydroxy moiety
    • 18087801 1:CAS:528:DC%2BD1cXhtFOlu78%3D
    • F Jin XY Jin YL Jin DW Sohn SA Kim DH Sohn YC Kim HS Kim 2007 Structural requirements of 2′,4′,6′-tris(methoxymethoxy) chalcone derivatives for anti-inflammatory activity: the importance of a 2′-hydroxy moiety Arch Pharm Res 30 1359 1367 18087801 1:CAS:528:DC%2BD1cXhtFOlu78%3D
    • (2007) Arch Pharm Res , vol.30 , pp. 1359-1367
    • Jin, F.1    Jin, X.Y.2    Jin, Y.L.3    Sohn, D.W.4    Kim, S.A.5    Sohn, D.H.6    Kim, Y.C.7    Kim, H.S.8
  • 63
    • 52649122345 scopus 로고    scopus 로고
    • Structure activity relationship studies of anti-inflammatory TMMC derivatives: 4-dimethylamino group on the B ring responsible for lowering the potency
    • 18806957 1:CAS:528:DC%2BD1cXhtFegur%2FN
    • YL Jin XY Jin F Jin DH Sohn HS Kim 2008 Structure activity relationship studies of anti-inflammatory TMMC derivatives: 4-dimethylamino group on the B ring responsible for lowering the potency Arch Pharm Res 31 1145 1152 18806957 1:CAS:528:DC%2BD1cXhtFegur%2FN
    • (2008) Arch Pharm Res , vol.31 , pp. 1145-1152
    • Jin, Y.L.1    Jin, X.Y.2    Jin, F.3    Sohn, D.H.4    Kim, H.S.5
  • 66
    • 71749083439 scopus 로고    scopus 로고
    • Licorice isoliquiritigenin dampens angiogenic activity via inhibition of MAPK-responsive signaling pathways leading to induction of matrix metalloproteinases
    • 19157825 1:CAS:528:DC%2BD1MXhsV2ltbnP
    • SW Kang JS Choi YJ Choi JY Bae J Li DS Kim JL Kim SY Shin YJ Lee IS Kwun YH Kang 2010 Licorice isoliquiritigenin dampens angiogenic activity via inhibition of MAPK-responsive signaling pathways leading to induction of matrix metalloproteinases J Nutr Biochem 21 55 65 19157825 1:CAS:528:DC%2BD1MXhsV2ltbnP
    • (2010) J Nutr Biochem , vol.21 , pp. 55-65
    • Kang, S.W.1    Choi, J.S.2    Choi, Y.J.3    Bae, J.Y.4    Li, J.5    Kim, D.S.6    Kim, J.L.7    Shin, S.Y.8    Lee, Y.J.9    Kwun, I.S.10    Kang, Y.H.11
  • 67
    • 67349094497 scopus 로고    scopus 로고
    • Evaluation of antigenotoxic activity of isoliquiritin apioside from Glycyrrhiza glabra L
    • 19490840 1:CAS:528:DC%2BD1MXmtFertLg%3D
    • P Kaur S Kaur N Kumar B Singh S Kumar 2009 Evaluation of antigenotoxic activity of isoliquiritin apioside from Glycyrrhiza glabra L Toxicol In Vitro 23 680 686 19490840 1:CAS:528:DC%2BD1MXmtFertLg%3D
    • (2009) Toxicol in Vitro , vol.23 , pp. 680-686
    • Kaur, P.1    Kaur, S.2    Kumar, N.3    Singh, B.4    Kumar, S.5
  • 68
    • 45749142839 scopus 로고    scopus 로고
    • Induction of growth inhibition and apoptosis in human uterine leiomyoma cells by isoliquiritigenin
    • DOI 10.1177/1933719107312681
    • DC Kim S Ramachandran SH Baek SH Kwon KY Kwon SD Cha I Bae CH Cho 2008 Induction of growth inhibition and apoptosis in human uterine leiomyoma cells by isoliquiritigenin Reprod Sci 15 552 558 18487228 1:CAS:528:DC%2BD1cXovFCjt78%3D (Pubitemid 351875956)
    • (2008) Reproductive Sciences , vol.15 , Issue.6 , pp. 552-558
    • Kim, D.-C.1    Ramachandran, S.2    Baek, S.-H.3    Kwon, S.-H.4    Kwon, K.-Y.5    Cha, S.-D.6    Bae, I.7    Cho, C.-H.8
  • 69
    • 33748876011 scopus 로고    scopus 로고
    • Design and biological evaluation of novel tubulin inhibitors as antimitotic agents using a pharmacophore binding model with tubulin
    • DOI 10.1021/jm050761i
    • Y Kim do KH Kim ND Kim KY Lee CK Han JH Yoon SK Moon SS Lee BL Seong 2006 Design and biological evaluation of novel tubulin inhibitors as antimitotic agents using a pharmacophore binding model with tubulin J Med Chem 49 5664 5670 16970393 (Pubitemid 44423705)
    • (2006) Journal of Medicinal Chemistry , vol.49 , Issue.19 , pp. 5664-5670
    • Kim, D.Y.1    Kim, K.-H.2    Kim, N.D.3    Lee, K.Y.4    Han, C.K.5    Yoon, J.H.6    Moon, S.K.7    Lee, S.S.8    Seong, B.L.9
  • 70
    • 41149091553 scopus 로고    scopus 로고
    • Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-kappaB in RAW 264.7 macrophages
    • 18295200 1:CAS:528:DC%2BD1cXktVKrsLY%3D
    • JY Kim SJ Park KJ Yun YW Cho HJ Park KT Lee 2008 Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-kappaB in RAW 264.7 macrophages Eur J Pharmacol 584 175 184 18295200 1:CAS:528:DC%2BD1cXktVKrsLY%3D
    • (2008) Eur J Pharmacol , vol.584 , pp. 175-184
    • Kim, J.Y.1    Park, S.J.2    Yun, K.J.3    Cho, Y.W.4    Park, H.J.5    Lee, K.T.6
  • 71
    • 52649126205 scopus 로고    scopus 로고
    • Butein sensitizes human leukemia cells to apoptosis induced by tumor necrosis factor-related apoptosis inducing ligand (TRAIL)
    • 18806962 1:CAS:528:DC%2BD1cXhtFegtbfJ
    • N Kim 2008 Butein sensitizes human leukemia cells to apoptosis induced by tumor necrosis factor-related apoptosis inducing ligand (TRAIL) Arch Pharm Res 31 1179 1186 18806962 1:CAS:528:DC%2BD1cXhtFegtbfJ
    • (2008) Arch Pharm Res , vol.31 , pp. 1179-1186
    • Kim, N.1
  • 72
    • 0034997805 scopus 로고    scopus 로고
    • Butein, a plant polyphenol, induces apoptosis concomitant with increased caspase-3 activity, decreased Bcl-2 expression and increased Bax expression in HL-60 cells
    • 11393587 1:CAS:528:DC%2BD3MXktVWmtbs%3D
    • NY Kim HO Pae GS Oh TH Kang YC Kim HY Rhew HT Chung 2001 Butein, a plant polyphenol, induces apoptosis concomitant with increased caspase-3 activity, decreased Bcl-2 expression and increased Bax expression in HL-60 cells Pharmacol Toxicol 88 261 266 11393587 1:CAS:528:DC%2BD3MXktVWmtbs%3D
    • (2001) Pharmacol Toxicol , vol.88 , pp. 261-266
    • Kim, N.Y.1    Pae, H.O.2    Oh, G.S.3    Kang, T.H.4    Kim, Y.C.5    Rhew, H.Y.6    Chung, H.T.7
  • 73
    • 16244417790 scopus 로고    scopus 로고
    • New anticancer agents: In vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants
    • New Anticancer Agents
    • Y Kimura 2005 New anticancer agents: in vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants In Vivo 19 37 60 15796155 1:CAS:528:DC%2BD2MXjtFyisro%3D (Pubitemid 40450377)
    • (2005) In Vivo , vol.19 , Issue.1 , pp. 37-60
    • Kimura, Y.1
  • 74
    • 0038166888 scopus 로고    scopus 로고
    • Antitumor and antimetastatic activities of Angelica keiskei roots, part 1: Isolation of an active substance, xanthoangelol
    • DOI 10.1002/ijc.11256
    • Y Kimura K Baba 2003 Antitumor and antimetastatic activities of Angelica keiskei roots, part 1: isolation of an active substance, xanthoangelol Int J Cancer 106 429 437 12845685 1:CAS:528:DC%2BD3sXlvF2hsrY%3D (Pubitemid 36870408)
    • (2003) International Journal of Cancer , vol.106 , Issue.3 , pp. 429-437
    • Kimura, Y.1    Baba, K.2
  • 75
    • 1842536365 scopus 로고    scopus 로고
    • Antitumor and antimetastatic activities of 4-hydroxyderricin isolated from Angelica keiskei roots
    • DOI 10.1055/s-2004-815537
    • Y Kimura M Taniguchi K Baba 2004 Antitumor and antimetastatic activities of 4-hydroxyderricin isolated from Angelica keiskei roots Planta Med 70 211 219 15114497 1:CAS:528:DC%2BD2cXivFCht74%3D (Pubitemid 38445186)
    • (2004) Planta Medica , vol.70 , Issue.3 , pp. 211-219
    • Kimura, Y.1    Taniguchi, M.2    Baba, K.3
  • 76
    • 0028826188 scopus 로고
    • Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro
    • 8593441 1:CAS:528:DyaK2MXpsFCntrg%3D
    • S Kobayashi T Miyamoto I Kimura M Kimura 1995 Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro Biol Pharm Bull 18 1382 1386 8593441 1:CAS:528: DyaK2MXpsFCntrg%3D
    • (1995) Biol Pharm Bull , vol.18 , pp. 1382-1386
    • Kobayashi, S.1    Miyamoto, T.2    Kimura, I.3    Kimura, M.4
  • 77
    • 70349100757 scopus 로고    scopus 로고
    • Decreasing unpalatable flavonoid components in Citrus: The effect of transformation construct
    • 19656329 1:CAS:528:DC%2BD1MXhtF2qs7jI
    • U Koca MA Berhow VJ Febres KI Champ O Carrillo-Mendoza GA Moore 2009 Decreasing unpalatable flavonoid components in Citrus: the effect of transformation construct Physiol Plant 137 101 114 19656329 1:CAS:528: DC%2BD1MXhtF2qs7jI
    • (2009) Physiol Plant , vol.137 , pp. 101-114
    • Koca, U.1    Berhow, M.A.2    Febres, V.J.3    Champ, K.I.4    Carrillo-Mendoza, O.5    Moore, G.A.6
  • 78
    • 76649133808 scopus 로고    scopus 로고
    • A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent
    • 20006519 1:CAS:528:DC%2BC3cXot12htA%3D%3D
    • Y Kong K Wang MC Edler E Hamel SL Mooberry MA Paige ML Brown 2010 A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent Bioorg Med Chem 18 971 977 20006519 1:CAS:528:DC%2BC3cXot12htA%3D%3D
    • (2010) Bioorg Med Chem , vol.18 , pp. 971-977
    • Kong, Y.1    Wang, K.2    Edler, M.C.3    Hamel, E.4    Mooberry, S.L.5    Paige, M.A.6    Brown, M.L.7
  • 79
    • 25144434945 scopus 로고    scopus 로고
    • Structure-based discovery of a boronic acid bioisostere of combretastatin A-4
    • DOI 10.1016/j.chembiol.2005.06.016, PII S1074552105002334
    • Y Kong J Grembecka MC Edler E Hamel SL Mooberry M Sabat J Rieger ML Brown 2005 Structure-based discovery of a boronic acid bioisostere of combretastatin A-4 Chem Biol 12 1007 1014 16183025 1:CAS:528:DC%2BD2MXhtVehsrfF (Pubitemid 41338811)
    • (2005) Chemistry and Biology , vol.12 , Issue.9 , pp. 1007-1014
    • Kong, Y.1    Grembecka, J.2    Edler, M.C.3    Hamel, E.4    Mooberry, S.L.5    Sabat, M.6    Rieger, J.7    Brown, M.L.8
  • 80
    • 0035025124 scopus 로고    scopus 로고
    • Mechanisms of carcinogenesis: Focus on oxidative stress and electron transfer
    • P Kovacic JD Jacintho 2001 Mechanisms of carcinogenesis: focus on oxidative stress and electron transfer Curr Med Chem 8 773 796 11375749 1:CAS:528:DC%2BD3MXjsVChtbY%3D (Pubitemid 32427906)
    • (2001) Current Medicinal Chemistry , vol.8 , Issue.7 , pp. 773-796
    • Kovacic, P.1    Jacintho, J.D.2
  • 81
    • 34047236705 scopus 로고    scopus 로고
    • Isoliquiritigenin inhibits IκB kinase activity and ROS generation to block TNF-α induced expression of cell adhesion molecules on human endothelial cells
    • DOI 10.1016/j.bcp.2007.01.015, PII S0006295207000275
    • S Kumar A Sharma B Madan V Singhal B Ghosh 2007 Isoliquiritigenin inhibits IkappaB kinase activity and ROS generation to block TNF-alpha induced expression of cell adhesion molecules on human endothelial cells Biochem Pharmacol 73 1602 1612 17276410 1:CAS:528:DC%2BD2sXjvFOmtb0%3D (Pubitemid 46533973)
    • (2007) Biochemical Pharmacology , vol.73 , Issue.10 , pp. 1602-1612
    • Kumar, S.1    Sharma, A.2    Madan, B.3    Singhal, V.4    Ghosh, B.5
  • 82
    • 77953534370 scopus 로고    scopus 로고
    • Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells
    • Kuo Y-F (2010) Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells. Free Radic Biol Med 49
    • (2010) Free Radic Biol Med , vol.49
    • Kuo, Y.-F.1
  • 83
    • 68249127978 scopus 로고    scopus 로고
    • Isoliquiritigenin inhibits migration and invasion of prostate cancer cells: Possible mediation by decreased JNK/AP-1 signaling
    • 18824345 1:CAS:528:DC%2BD1MXhtVSntrbK
    • GT Kwon HJ Cho WY Chung KK Park A Moon JH Park 2009 Isoliquiritigenin inhibits migration and invasion of prostate cancer cells: possible mediation by decreased JNK/AP-1 signaling J Nutr Biochem 20 663 676 18824345 1:CAS:528:DC%2BD1MXhtVSntrbK
    • (2009) J Nutr Biochem , vol.20 , pp. 663-676
    • Kwon, G.T.1    Cho, H.J.2    Chung, W.Y.3    Park, K.K.4    Moon, A.5    Park, J.H.6
  • 84
    • 33846849163 scopus 로고    scopus 로고
    • Blockade of cytokine-induced endothelial cell adhesion molecule expression by licorice isoliquiritigenin through NF-kappaB signal disruption
    • 1:CAS:528:DC%2BD2sXhsVWjt7k%3D
    • HM Kwon YJ Choi JS Choi SW Kang JY Bae IJ Kang JG Jun SS Lee SS Lim YH Kang 2007 Blockade of cytokine-induced endothelial cell adhesion molecule expression by licorice isoliquiritigenin through NF-kappaB signal disruption Exp Biol Med (Maywood) 232 235 245 1:CAS:528:DC%2BD2sXhsVWjt7k%3D
    • (2007) Exp Biol Med (Maywood) , vol.232 , pp. 235-245
    • Kwon, H.M.1    Choi, Y.J.2    Choi, J.S.3    Kang, S.W.4    Bae, J.Y.5    Kang, I.J.6    Jun, J.G.7    Lee, S.S.8    Lim, S.S.9    Kang, Y.H.10
  • 85
    • 54249164448 scopus 로고    scopus 로고
    • Licochalcone A isolated from licorice suppresses lipopolysaccharide- stimulated inflammatory reactions in RAW264.7 cells and endotoxin shock in mice
    • 18825356 1:CAS:528:DC%2BD1cXht1Kns7rJ
    • HS Kwon JH Park DH Kim YH Kim HK Shin JK Kim 2008 Licochalcone A isolated from licorice suppresses lipopolysaccharide-stimulated inflammatory reactions in RAW264.7 cells and endotoxin shock in mice J Mol Med 86 1287 1295 18825356 1:CAS:528:DC%2BD1cXht1Kns7rJ
    • (2008) J Mol Med , vol.86 , pp. 1287-1295
    • Kwon, H.S.1    Park, J.H.2    Kim, D.H.3    Kim, Y.H.4    Shin, H.K.5    Kim, J.K.6
  • 88
    • 0035808202 scopus 로고    scopus 로고
    • Chalcones are potent inhibitors of aromatase and 17β-hydroxysteroid dehydrogenase activities
    • DOI 10.1016/S0024-3205(00)00974-7, PII S0024320500009747
    • JC Le Bail C Pouget C Fagnere JP Basly AJ Chulia G Habrioux 2001 Chalcones are potent inhibitors of aromatase and 17beta-hydroxysteroid dehydrogenase activities Life Sci 68 751 761 11205867 1:CAS:528: DC%2BD3MXkvVWhsg%3D%3D (Pubitemid 32168006)
    • (2001) Life Sciences , vol.68 , Issue.7 , pp. 751-761
    • Le Bail, J.-C.1    Pouget, C.2    Fagnere, C.3    Basly, J.-P.4    Chulia, A.-J.5    Habrioux, G.6
  • 89
    • 41549142696 scopus 로고    scopus 로고
    • Isoliquiritigenin inhibits tumor growth and protects the kidney and liver against chemotherapy-induced toxicity in a mouse xenograft model of colon carcinoma
    • DOI 10.1254/jphs.FP0071498
    • CK Lee SH Son KK Park JH Park SS Lim WY Chung 2008 Isoliquiritigenin inhibits tumor growth and protects the kidney and liver against chemotherapy-induced toxicity in a mouse xenograft model of colon carcinoma J Pharmacol Sci 106 444 451 18360095 1:CAS:528:DC%2BD1cXktlWls7g%3D (Pubitemid 351468597)
    • (2008) Journal of Pharmacological Sciences , vol.106 , Issue.3 , pp. 444-451
    • Chang, K.L.1    Seung, H.S.2    Kwang, K.P.3    Park, J.H.Y.4    Soon, S.L.5    Won, Y.C.6
  • 90
    • 45749128172 scopus 로고    scopus 로고
    • Licochalcone a inhibits the growth of colon carcinoma and attenuates cisplatin-induced toxicity without a loss of chemotherapeutic efficacy in mice
    • DOI 10.1111/j.1742-7843.2008.00238.x
    • CK Lee SH Son KK Park JH Park SS Lim SH Kim WY Chung 2008 Licochalcone A inhibits the growth of colon carcinoma and attenuates cisplatin-induced toxicity without a loss of chemotherapeutic efficacy in mice Basic Clin Pharmacol Toxicol 103 48 54 18484961 1:CAS:528:DC%2BD1cXotlKisLY%3D (Pubitemid 351874534)
    • (2008) Basic and Clinical Pharmacology and Toxicology , vol.103 , Issue.1 , pp. 48-54
    • Lee, C.K.1    Son, S.H.2    Park, K.K.3    Park, J.H.Y.4    Lim, S.S.5    Kim, S.-H.6    Chung, W.Y.7
  • 91
    • 65449132740 scopus 로고    scopus 로고
    • Blockade of four-transmembrane L6 family member 5 (TM4SF5)-mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative
    • 19177595 1:CAS:528:DC%2BD1MXkslWjs7w%3D
    • SA Lee HW Ryu YM Kim S Choi MJ Lee TK Kwak HJ Kim M Cho KH Park JW Lee 2009 Blockade of four-transmembrane L6 family member 5 (TM4SF5)-mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative Hepatology 49 1316 1325 19177595 1:CAS:528:DC%2BD1MXkslWjs7w%3D
    • (2009) Hepatology , vol.49 , pp. 1316-1325
    • Lee, S.A.1    Ryu, H.W.2    Kim, Y.M.3    Choi, S.4    Lee, M.J.5    Kwak, T.K.6    Kim, H.J.7    Cho, M.8    Park, K.H.9    Lee, J.W.10
  • 92
    • 35848968674 scopus 로고    scopus 로고
    • Butein blocks tumor necrosis factor α-induced interleukin 8 and matrix metalloproteinase 7 production by inhibiting p38 kinase and osteopontin mediated signaling events in HT-29 cells
    • DOI 10.1016/j.lfs.2007.09.024, PII S0024320507007370
    • SH Lee GS Seo XY Jin G Ko DH Sohn 2007 Butein blocks tumor necrosis factor alpha-induced interleukin 8 and matrix metalloproteinase 7 production by inhibiting p38 kinase and osteopontin mediated signaling events in HT-29 cells Life Sci 81 1535 1543 17977560 1:CAS:528:DC%2BD2sXht1ylsr7J (Pubitemid 350060926)
    • (2007) Life Sciences , vol.81 , Issue.21-22 , pp. 1535-1543
    • Lee, S.H.1    Seo, G.S.2    Jin, X.Y.3    Ko, G.4    Sohn, D.H.5
  • 93
    • 65549152471 scopus 로고    scopus 로고
    • Isoliquiritigenin, from Dalbergia odorifera, up-regulates anti-inflammatory heme oxygenase-1 expression in RAW264.7 macrophages
    • 19169644 1:CAS:528:DC%2BD1MXltV2htbw%3D
    • SH Lee JY Kim GS Seo YC Kim DH Sohn 2009 Isoliquiritigenin, from Dalbergia odorifera, up-regulates anti-inflammatory heme oxygenase-1 expression in RAW264.7 macrophages Inflamm Res 58 257 262 19169644 1:CAS:528: DC%2BD1MXltV2htbw%3D
    • (2009) Inflamm Res , vol.58 , pp. 257-262
    • Lee, S.H.1    Kim, J.Y.2    Seo, G.S.3    Kim, Y.C.4    Sohn, D.H.5
  • 94
    • 33644526910 scopus 로고    scopus 로고
    • Heme oxygenase 1 mediates anti-inflammatory effects of 2′,4′,6′-tris(methoxymethoxy) chalcone
    • 16480975 1:CAS:528:DC%2BD28XhvVWltr8%3D
    • SH Lee GS Seo JY Kim XY Jin HD Kim DH Sohn 2006 Heme oxygenase 1 mediates anti-inflammatory effects of 2′,4′,6′-tris(methoxymethoxy) chalcone Eur J Pharmacol 532 178 186 16480975 1:CAS:528:DC%2BD28XhvVWltr8%3D
    • (2006) Eur J Pharmacol , vol.532 , pp. 178-186
    • Lee, S.H.1    Seo, G.S.2    Kim, J.Y.3    Jin, X.Y.4    Kim, H.D.5    Sohn, D.H.6
  • 95
    • 33750002720 scopus 로고    scopus 로고
    • 2′,4′,6′-Tris(methoxymethoxy) chalcone attenuates hepatic stellate cell proliferation by a heme oxygenase-dependent pathway
    • DOI 10.1016/j.bcp.2006.08.004, PII S0006295206004989
    • SH Lee GS Seo HS Kim SW Woo G Ko DH Sohn 2006 2′,4′,6′- Tris(methoxymethoxy) chalcone attenuates hepatic stellate cell proliferation by a heme oxygenase-dependent pathway Biochem Pharmacol 72 1322 1333 16982036 1:CAS:528:DC%2BD28XhtFSrtLrO (Pubitemid 44572190)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.10 , pp. 1322-1333
    • Lee, S.H.1    Seo, G.S.2    Kim, H.S.3    Woo, S.W.4    Ko, G.5    Sohn, D.H.6
  • 96
    • 34547661858 scopus 로고    scopus 로고
    • 2′,4′,6′-Tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-α-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways
    • DOI 10.1016/j.bcp.2007.06.034, PII S0006295207004121
    • SH Lee DH Sohn XY Jin SW Kim SC Choi GS Seo 2007 2′,4′, 6′-tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-alpha-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways Biochem Pharmacol 74 870 880 17678632 1:CAS:528:DC%2BD2sXovFOjt70%3D (Pubitemid 47212081)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.6 , pp. 870-880
    • Lee, S.H.1    Sohn, D.H.2    Jin, X.Y.3    Kim, S.W.4    Choi, S.C.5    Seo, G.S.6
  • 97
    • 64949183401 scopus 로고    scopus 로고
    • Induction of cell cycle arrest in prostate cancer cells by the dietary compound isoliquiritigenin
    • 19298190
    • YM Lee Y Lim do HJ Choi JI Jung WY Chung JH Park 2009 Induction of cell cycle arrest in prostate cancer cells by the dietary compound isoliquiritigenin J Med Food 12 8 14 19298190
    • (2009) J Med Food , vol.12 , pp. 8-14
    • Lee, Y.M.1    Lim Do, Y.2    Choi, H.J.3    Jung, J.I.4    Chung, W.Y.5    Park, J.H.6
  • 98
    • 77649180814 scopus 로고    scopus 로고
    • Isoliquiritigenin 2′-methyl ether induces growth inhibition and apoptosis in oral cancer cells via heme oxygenase-1
    • 20040371 1:CAS:528:DC%2BC3cXjtVSgsr4%3D
    • YM Lee GS Jeong HD Lim RB An YC Kim EC Kim 2010 Isoliquiritigenin 2′-methyl ether induces growth inhibition and apoptosis in oral cancer cells via heme oxygenase-1 Toxicol In Vitro 24 776 782 20040371 1:CAS:528:DC%2BC3cXjtVSgsr4%3D
    • (2010) Toxicol in Vitro , vol.24 , pp. 776-782
    • Lee, Y.M.1    Jeong, G.S.2    Lim, H.D.3    An, R.B.4    Kim, Y.C.5    Kim, E.C.6
  • 99
    • 33646440301 scopus 로고    scopus 로고
    • Anti-angiogenic and anti-tumor activities of 2′-hydroxy-4′- methoxychalcone
    • 16651739 1:CAS:528:DC%2BD28Xmt1ehtbw%3D
    • YS Lee SS Lim KH Shin YS Kim K Ohuchi SH Jung 2006 Anti-angiogenic and anti-tumor activities of 2′-hydroxy-4′-methoxychalcone Biol Pharm Bull 29 1028 1031 16651739 1:CAS:528:DC%2BD28Xmt1ehtbw%3D
    • (2006) Biol Pharm Bull , vol.29 , pp. 1028-1031
    • Lee, Y.S.1    Lim, S.S.2    Shin, K.H.3    Kim, Y.S.4    Ohuchi, K.5    Jung, S.H.6
  • 101
    • 66149119356 scopus 로고    scopus 로고
    • ON-III inhibits erbB-2 tyrosine kinase receptor signal pathway and triggers apoptosis through induction of Bim in breast cancer cells
    • 19242112 1:CAS:528:DC%2BD1MXotFSjt7s%3D
    • DD Li XQ Wu J Tang XY Wei XF Zhu 2009 ON-III inhibits erbB-2 tyrosine kinase receptor signal pathway and triggers apoptosis through induction of Bim in breast cancer cells Cancer Biol Ther 8 739 743 19242112 1:CAS:528: DC%2BD1MXotFSjt7s%3D
    • (2009) Cancer Biol Ther , vol.8 , pp. 739-743
    • Li, D.D.1    Wu, X.Q.2    Tang, J.3    Wei, X.Y.4    Zhu, X.F.5
  • 102
    • 43749087342 scopus 로고    scopus 로고
    • Cytotoxic constituents from Brazilian red propolis and their structure-activity relationship
    • DOI 10.1016/j.bmc.2008.04.016, PII S0968089608003295
    • F Li S Awale Y Tezuka S Kadota 2008 Cytotoxic constituents from Brazilian red propolis and their structure-activity relationship Bioorg Med Chem 16 5434 5440 18440233 1:CAS:528:DC%2BD1cXmsVanu74%3D (Pubitemid 351694485)
    • (2008) Bioorganic and Medicinal Chemistry , vol.16 , Issue.10 , pp. 5434-5440
    • Li, F.1    Awale, S.2    Tezuka, Y.3    Kadota, S.4
  • 103
    • 33746075933 scopus 로고    scopus 로고
    • Chrysin inhibits lipopolysaccharide-induced angiogenesis via down-regulation of VEGF/VEGFR-2(KDR) and IL-6/IL-6R pathways
    • DOI 10.1055/s-2006-931602
    • CM Lin H Chang SY Li IH Wu JH Chiu 2006 Chrysin inhibits lipopolysaccharide-induced angiogenesis via down-regulation of VEGF/VEGFR-2(KDR) and IL-6/IL-6R pathways Planta Med 72 708 714 16732516 1:CAS:528: DC%2BD28Xpt1Shtrs%3D (Pubitemid 44073454)
    • (2006) Planta Medica , vol.72 , Issue.8 , pp. 708-714
    • Lin, C.-M.1    Chang, H.2    Li, S.-Y.3    Wu, I.-H.4    Chiu, J.-H.5
  • 104
    • 33845248255 scopus 로고    scopus 로고
    • Wogonin inhibits IL-6-induced angiogenesis via down-regulation of VEGF and VEGFR-1, not VEGFR-2
    • DOI 10.1055/s-2006-951692
    • CM Lin H Chang YH Chen IH Wu JH Chiu 2006 Wogonin inhibits IL-6-induced angiogenesis via down-regulation of VEGF and VEGFR-1, not VEGFR-2 Planta Med 72 1305 1310 17024605 1:CAS:528:DC%2BD28Xht1GrtrfP (Pubitemid 44862032)
    • (2006) Planta Medica , vol.72 , Issue.14 , pp. 1305-1310
    • Lin, C.-M.1    Chang, H.2    Chen, Y.-H.3    Wu, I.-H.4    Chiu, J.-H.5
  • 105
    • 33748421494 scopus 로고    scopus 로고
    • Protective role of wogonin against lipopolysaccharide-induced angiogenesis via VEGFR-2, not VEGFR-1
    • DOI 10.1016/j.intimp.2006.07.003, PII S1567576906002037
    • CM Lin H Chang YH Chen SY Li IH Wu JH Chiu 2006 Protective role of wogonin against lipopolysaccharide-induced angiogenesis via VEGFR-2, not VEGFR-1 Int Immunopharmacol 6 1690 1698 16979123 1:CAS:528:DC%2BD28Xps1Cmsbs%3D (Pubitemid 44344541)
    • (2006) International Immunopharmacology , vol.6 , Issue.11 , pp. 1690-1698
    • Lin, C.-M.1    Chang, H.2    Chen, Y.-H.3    Li, S.Y.4    Wu, I.-H.5    Chiu, J.-H.6
  • 106
    • 27744559989 scopus 로고    scopus 로고
    • Antiproliferative properties of piperidinylchalcones
    • DOI 10.1016/j.bmc.2005.08.006, PII S0968089605007388
    • X Liu ML Go 2006 Antiproliferative properties of piperidinylchalcones Bioorg Med Chem 14 153 163 16185876 1:CAS:528:DC%2BD2MXht1egsLzI (Pubitemid 41635479)
    • (2006) Bioorganic and Medicinal Chemistry , vol.14 , Issue.1 , pp. 153-163
    • Liu, X.1    Go, M.-L.2
  • 107
    • 34548838273 scopus 로고    scopus 로고
    • Antiproliferative activity of chalcones with basic functionalities
    • DOI 10.1016/j.bmc.2007.07.042, PII S0968089607006591
    • X Liu ML Go 2007 Antiproliferative activity of chalcones with basic functionalities Bioorg Med Chem 15 7021 7034 17804245 1:CAS:528: DC%2BD2sXhtFWiur7M (Pubitemid 47451792)
    • (2007) Bioorganic and Medicinal Chemistry , vol.15 , Issue.22 , pp. 7021-7034
    • Liu, X.1    Go, M.-L.2
  • 108
    • 33847633373 scopus 로고    scopus 로고
    • Chalcone inhibits the activation of NF-kappaB and STAT3 in endothelial cells via endogenous electrophile
    • 17320913 1:CAS:528:DC%2BD2sXislKgt7Y%3D
    • YC Liu CW Hsieh CC Wu BS Wung 2007 Chalcone inhibits the activation of NF-kappaB and STAT3 in endothelial cells via endogenous electrophile Life Sci 80 1420 1430 17320913 1:CAS:528:DC%2BD2sXislKgt7Y%3D
    • (2007) Life Sci , vol.80 , pp. 1420-1430
    • Liu, Y.C.1    Hsieh, C.W.2    Wu, C.C.3    Wung, B.S.4
  • 109
    • 63949084699 scopus 로고    scopus 로고
    • Studies of structure-activity relationship on plant polyphenol-induced suppression of human liver cancer cells
    • 18766342 1:CAS:528:DC%2BD1MXjslOlurs%3D
    • J Loa P Chow K Zhang 2009 Studies of structure-activity relationship on plant polyphenol-induced suppression of human liver cancer cells Cancer Chemother Pharmacol 63 1007 1016 18766342 1:CAS:528:DC%2BD1MXjslOlurs%3D
    • (2009) Cancer Chemother Pharmacol , vol.63 , pp. 1007-1016
    • Loa, J.1    Chow, P.2    Zhang, K.3
  • 110
    • 67649340805 scopus 로고    scopus 로고
    • Preliminary studies on anti-tumor activity of 2′,4′- dihydroxychalcone isolated from Herba Oxytropis in human gastric cancer MGC-803 cells
    • 19457454 1:CAS:528:DC%2BD1MXotFyls78%3D
    • C Lou M Wang G Yang H Cai Y Li F Zhao H Yang L Tong B Cai 2009 Preliminary studies on anti-tumor activity of 2′,4′- dihydroxychalcone isolated from Herba Oxytropis in human gastric cancer MGC-803 cells Toxicol In Vitro 23 906 910 19457454 1:CAS:528:DC%2BD1MXotFyls78%3D
    • (2009) Toxicol in Vitro , vol.23 , pp. 906-910
    • Lou, C.1    Wang, M.2    Yang, G.3    Cai, H.4    Li, Y.5    Zhao, F.6    Yang, H.7    Tong, L.8    Cai, B.9
  • 111
    • 0034765176 scopus 로고    scopus 로고
    • Apoptosis induced by isoliquiritigenin in human gastric cancer MGC-803 cells
    • J Ma NY Fu DB Pang WY Wu AL Xu 2001 Apoptosis induced by isoliquiritigenin in human gastric cancer MGC-803 cells Planta Med 67 754 757 11731922 1:CAS:528:DC%2BD3MXosVylt74%3D (Pubitemid 33044487)
    • (2001) Planta Medica , vol.67 , Issue.8 , pp. 754-757
    • Ma, J.1    Fu, N.-Y.2    Pang, D.-B.3    Wu, W.-Y.4    Xu, A.-L.5
  • 112
    • 34250818796 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of (±)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer
    • DOI 10.1021/jm070109i
    • A Maiti M Cuendet VL Croy DC Endringer JM Pezzuto M Cushman 2007 Synthesis and biological evaluation of (±)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer J Med Chem 50 2799 2806 17511439 1:CAS:528:DC%2BD2sXlsVKjtLo%3D (Pubitemid 46980851)
    • (2007) Journal of Medicinal Chemistry , vol.50 , Issue.12 , pp. 2799-2806
    • Maiti, A.1    Cuendet, M.2    Croy, V.L.3    Endringer, D.C.4    Pezzuto, J.M.5    Cushman, M.6
  • 113
    • 0029946420 scopus 로고    scopus 로고
    • Chemoprevention of 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis by the dietary flavonoids chalcone, 2-hydroxychalcone, and quercetin
    • H Makita T Tanaka H Fujitsuka N Tatematsu K Satoh A Hara H Mori 1996 Chemoprevention of 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis by the dietary flavonoids chalcone, 2-hydroxychalcone, and quercetin Cancer Res 56 4904 4909 8895742 1:CAS:528:DyaK28XmsFygtr4%3D (Pubitemid 26374427)
    • (1996) Cancer Research , vol.56 , Issue.21 , pp. 4904-4909
    • Makita, H.1    Tanaka, T.2    Fujitsuka, H.3    Tatematsu, N.4    Satoh, K.5    Hara, A.6    Mori, H.7
  • 115
    • 0038004740 scopus 로고    scopus 로고
    • Targeting JNK for therapeutic benefit: From junk to gold?
    • DOI 10.1038/nrd1132
    • AM Manning RJ Davis 2003 Targeting JNK for therapeutic benefit: from junk to gold? Nat Rev Drug Discov 2 554 565 12815381 1:CAS:528:DC%2BD3sXks1Oru7c%3D (Pubitemid 37361747)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.7 , pp. 554-565
    • Manning, A.M.1    Davis, R.J.2
  • 116
    • 31544447710 scopus 로고    scopus 로고
    • Orally administered green tea polyphenols prevent ultraviolet radiation-induced skin cancer in mice through activation of cytotoxic T cells and inhibition of angiogenesis in tumors
    • SK Mantena SM Meeran CA Elmets SK Katiyar 2005 Orally administered green tea polyphenols prevent ultraviolet radiation-induced skin cancer in mice through activation of cytotoxic T cells and inhibition of angiogenesis in tumors J Nutr 135 2871 2877 16317135 1:CAS:528:DC%2BD2MXhtlalsLvO (Pubitemid 43156556)
    • (2005) Journal of Nutrition , vol.135 , Issue.12 , pp. 2871-2877
    • Mantena, S.K.1    Meeran, S.M.2    Elmets, C.A.3    Katiyar, S.K.4
  • 118
    • 0030639540 scopus 로고    scopus 로고
    • Hydrogen bond formation as basis for radical scavenging activity: A structure-activity study of C-methylated dihydrochalcones from Myrica gale and structurally related acetophenones
    • DOI 10.1016/S0891-5849(96)00277-8
    • L Mathiesen KE Malterud RB Sund 1997 Hydrogen bond formation as basis for radical scavenging activity: a structure-activity study of C-methylated dihydrochalcones from Myrica gale and structurally related acetophenones Free Radic Biol Med 22 307 311 8958155 1:CAS:528:DyaK28XnsVGju7s%3D (Pubitemid 26399336)
    • (1996) Free Radical Biology and Medicine , vol.22 , Issue.1-2 , pp. 307-311
    • Mathiesen, L.1    Malterud, K.E.2    Sund, R.B.3
  • 120
    • 74849131331 scopus 로고    scopus 로고
    • Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation
    • 19643530 1:CAS:528:DC%2BC3cXhtlSjurc%3D
    • DO Moon MO Kim YH Choi JW Hyun WY Chang GY Kim 2010 Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation Cancer Lett 288 204 213 19643530 1:CAS:528:DC%2BC3cXhtlSjurc%3D
    • (2010) Cancer Lett , vol.288 , pp. 204-213
    • Moon, D.O.1    Kim, M.O.2    Choi, Y.H.3    Hyun, J.W.4    Chang, W.Y.5    Kim, G.Y.6
  • 124
    • 0035856010 scopus 로고    scopus 로고
    • Chemokines and the molecular basis of cancer metastasis
    • 11556308 1:CAS:528:DC%2BD3MXntFCnsbk%3D
    • PM Murphy 2001 Chemokines and the molecular basis of cancer metastasis N Engl J Med 345 833 835 11556308 1:CAS:528:DC%2BD3MXntFCnsbk%3D
    • (2001) N Engl J Med , vol.345 , pp. 833-835
    • Murphy, P.M.1
  • 125
    • 18444370239 scopus 로고    scopus 로고
    • Induction of apoptosis in human promyelocytic leukemia cell line HL-60 by C-benzylated dihydrochalcones, uvaretin, isouvaretin and diuvaretin
    • DOI 10.1248/bpb.28.83
    • N Nakatani M Ichimaru M Moriyasu A Kato 2005 Induction of apoptosis in human promyelocytic leukemia cell line HL-60 by C-benzylated dihydrochalcones, uvaretin, isouvaretin and diuvaretin Biol Pharm Bull 28 83 86 15635168 1:CAS:528:DC%2BD2MXjsVejtrs%3D (Pubitemid 40879788)
    • (2005) Biological and Pharmaceutical Bulletin , vol.28 , Issue.1 , pp. 83-86
    • Nakatani, N.1    Ichimaru, M.2    Moriyasu, M.3    Kato, A.4
  • 127
    • 0028158941 scopus 로고
    • Effects of naturally occurring flavonoids on mitogen-induced lymphocyte proliferation and mixed lymphocyte culture
    • DOI 10.1016/0024-3205(94)00787-X
    • SY Namgoong KH Son HW Chang SS Kang HP Kim 1994 Effects of naturally occurring flavonoids on mitogen-induced lymphocyte proliferation and mixed lymphocyte culture Life Sci 54 313 320 8289592 1:CAS:528:DyaK2cXhsFaqur0%3D (Pubitemid 24049591)
    • (1994) Life Sciences , vol.54 , Issue.5 , pp. 313-320
    • Namgoong, S.Y.1    Son, K.H.2    Chang, H.W.3    Kang, S.S.4    Kim, H.P.5
  • 129
    • 11144237662 scopus 로고    scopus 로고
    • Antiangiogenic properties of natural polyphenols from red wine and green tea
    • DOI 10.1016/j.jnutbio.2004.09.004, PII S0955286304001792
    • MH Oak J El Bedoui VB Schini-Kerth 2005 Antiangiogenic properties of natural polyphenols from red wine and green tea J Nutr Biochem 16 1 8 15629234 1:CAS:528:DC%2BD2MXjtl2g (Pubitemid 40052710)
    • (2005) Journal of Nutritional Biochemistry , vol.16 , Issue.1 , pp. 1-8
    • Oak, M.-H.1    El Bedoui, J.2    Schini-Kerth, V.B.3
  • 130
    • 4644287416 scopus 로고    scopus 로고
    • Red wine polyphenolic compounds strongly inhibit pro-matrix metalloproteinase-2 expression and its activation in response to thrombin via direct inhibition of membrane type 1-matrix metalloproteinase in vascular smooth muscle cells
    • DOI 10.1161/01.CIR.0000142617.52881.F4
    • MH Oak J El Bedoui P Anglard VB Schini-Kerth 2004 Red wine polyphenolic compounds strongly inhibit pro-matrix metalloproteinase-2 expression and its activation in response to thrombin via direct inhibition of membrane type 1-matrix metalloproteinase in vascular smooth muscle cells Circulation 110 1861 1867 15364805 1:CAS:528:DC%2BD2cXnslems7o%3D (Pubitemid 39299230)
    • (2004) Circulation , vol.110 , Issue.13 , pp. 1861-1867
    • Oak, M.-H.1    El Bedoui, J.2    Anglard, P.3    Schini-Kerth, V.B.4
  • 131
    • 33749032411 scopus 로고    scopus 로고
    • AB-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK
    • DOI 10.1038/sj.bjp.0706843, PII 0706843
    • MH Oak JE Bedoui SV Madeira K Chalupsky VB Schini-Kerth 2006 Delphinidin and cyanidin inhibit PDGF(AB)-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK Br J Pharmacol 149 283 290 16921400 1:CAS:528:DC%2BD28XhtVSgurrN (Pubitemid 44453429)
    • (2006) British Journal of Pharmacology , vol.149 , Issue.3 , pp. 283-290
    • Oak, M.-H.1    Bedoui, J.E.2    Madeira, S.V.F.3    Chalupsky, K.4    Schini-Kerth, V.B.5
  • 132
    • 0038120889 scopus 로고    scopus 로고
    • Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway
    • DOI 10.1161/01.ATV.0000070101.70534.38
    • MH Oak M Chataigneau T Keravis T Chataigneau A Beretz R Andriantsitohaina JC Stoclet SJ Chang VB Schini-Kerth 2003 Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway Arterioscler Thromb Vasc Biol 23 1001 1007 12676803 1:CAS:528: DC%2BD3sXktlantr4%3D (Pubitemid 36713552)
    • (2003) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.23 , Issue.6 , pp. 1001-1007
    • Oak, M.-H.1    Chataigneau, M.2    Keravis, T.3    Chataigneau, T.4    Beretz, A.5    Andriantsitohaina, R.6    Stoclet, J.-C.7    Chang, S.-J.8    Schini-Kerth, V.B.9
  • 133
    • 0028218474 scopus 로고
    • Chronic infections and inflammatory processes as cancer risk factors: Possible role of nitric oxide in carcinogenesis
    • DOI 10.1016/0027-5107(94)90245-3
    • H Ohshima H Bartsch 1994 Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis Mutat Res 305 253 264 7510036 1:CAS:528:DyaK2cXitFeqsrk%3D (Pubitemid 24082901)
    • (1994) Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis , vol.305 , Issue.2 , pp. 253-264
    • Ohshima, H.1    Bartsch, H.2
  • 134
    • 69249108878 scopus 로고    scopus 로고
    • Death receptor 5 promoter-enhancing compounds isolated from Catimbium speciosum and their enhancement effect on TRAIL-induced apoptosis
    • 19682913 1:CAS:528:DC%2BD1MXhtVOisL%2FI
    • T Ohtsuki H Kikuchi T Koyano T Kowithayakorn T Sakai M Ishibashi 2009 Death receptor 5 promoter-enhancing compounds isolated from Catimbium speciosum and their enhancement effect on TRAIL-induced apoptosis Bioorg Med Chem 17 6748 6754 19682913 1:CAS:528:DC%2BD1MXhtVOisL%2FI
    • (2009) Bioorg Med Chem , vol.17 , pp. 6748-6754
    • Ohtsuki, T.1    Kikuchi, H.2    Koyano, T.3    Kowithayakorn, T.4    Sakai, T.5    Ishibashi, M.6
  • 135
    • 0024424972 scopus 로고
    • A highly potent antiangiogenic activity of retinoids
    • DOI 10.1016/0304-3835(89)90054-2
    • T Oikawa K Hirotani O Nakamura K Shudo A Hiragun T Iwaguchi 1989 A highly potent antiangiogenic activity of retinoids Cancer Lett 48 157 162 2479461 1:CAS:528:DyaK3cXkvVerug%3D%3D (Pubitemid 19282158)
    • (1989) Cancer Letters , vol.48 , Issue.2 , pp. 157-162
    • Oikawa, T.1    Hirotani, K.2    Nakamura, O.3    Shudo, K.4    Hiragun, A.5    Iwaguchi, T.6
  • 136
    • 17144458301 scopus 로고    scopus 로고
    • Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
    • 10558995 1:CAS:528:DyaK1MXnsVersrg%3D
    • G Pages S Guerin D Grall F Bonino A Smith F Anjuere P Auberger J Pouyssegur 1999 Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice Science 286 1374 1377 10558995 1:CAS:528:DyaK1MXnsVersrg%3D
    • (1999) Science , vol.286 , pp. 1374-1377
    • Pages, G.1    Guerin, S.2    Grall, D.3    Bonino, F.4    Smith, A.5    Anjuere, F.6    Auberger, P.7    Pouyssegur, J.8
  • 137
    • 62149113324 scopus 로고    scopus 로고
    • Butein suppresses constitutive and inducible signal transducer and activator of transcription (STAT) 3 activation and STAT3-regulated gene products through the induction of a protein tyrosine phosphatase SHP-1
    • 19103760 1:CAS:528:DC%2BD1MXis1Wqu7Y%3D
    • MK Pandey B Sung KS Ahn BB Aggarwal 2009 Butein suppresses constitutive and inducible signal transducer and activator of transcription (STAT) 3 activation and STAT3-regulated gene products through the induction of a protein tyrosine phosphatase SHP-1 Mol Pharmacol 75 525 533 19103760 1:CAS:528:DC%2BD1MXis1Wqu7Y%3D
    • (2009) Mol Pharmacol , vol.75 , pp. 525-533
    • Pandey, M.K.1    Sung, B.2    Ahn, K.S.3    Aggarwal, B.B.4
  • 138
    • 34547125342 scopus 로고    scopus 로고
    • Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-κB and NF-κB-regulated gene expression through direct inhibition of IκBα kinase β on cysteine 179 residue
    • DOI 10.1074/jbc.M700890200
    • MK Pandey SK Sandur B Sung G Sethi AB Kunnumakkara BB Aggarwal 2007 Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue J Biol Chem 282 17340 17350 17439942 1:CAS:528:DC%2BD2sXmt1eksL4%3D (Pubitemid 47100316)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.24 , pp. 17340-17350
    • Pandey, M.K.1    Sandur, S.K.2    Sung, B.3    Sethi, G.4    Kunnumakkara, A.B.5    Aggarwal, B.B.6
  • 139
    • 62749157517 scopus 로고    scopus 로고
    • Isoliquiritigenin induces G2 and M phase arrest by inducing DNA damage and by inhibiting the metaphase/anaphase transition
    • 19167809 1:CAS:528:DC%2BD1MXjslOktbs%3D
    • I Park KK Park JH Park WY Chung 2009 Isoliquiritigenin induces G2 and M phase arrest by inducing DNA damage and by inhibiting the metaphase/anaphase transition Cancer Lett 277 174 181 19167809 1:CAS:528:DC%2BD1MXjslOktbs%3D
    • (2009) Cancer Lett , vol.277 , pp. 174-181
    • Park, I.1    Park, K.K.2    Park, J.H.3    Chung, W.Y.4
  • 140
    • 59449101744 scopus 로고    scopus 로고
    • YL-I-108, a synthetic chalcone derivative, inhibits lipopolysaccharide- stimulated nitric oxide production in RAW 264.7 murine macrophages: Involvement of heme oxygenase-1 induction and blockade of activator protein-1
    • 19183880 1:CAS:528:DC%2BD1MXhtFShu7Y%3D
    • PH Park HS Kim J Hur XY Jin YL Jin DH Sohn 2009 YL-I-108, a synthetic chalcone derivative, inhibits lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 murine macrophages: involvement of heme oxygenase-1 induction and blockade of activator protein-1 Arch Pharm Res 32 79 89 19183880 1:CAS:528:DC%2BD1MXhtFShu7Y%3D
    • (2009) Arch Pharm Res , vol.32 , pp. 79-89
    • Park, P.H.1    Kim, H.S.2    Hur, J.3    Jin, X.Y.4    Jin, Y.L.5    Sohn, D.H.6
  • 141
    • 60949091762 scopus 로고    scopus 로고
    • KB-34, a newly synthesized chalcone derivative, inhibits lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 macrophages via heme oxygenase-1 induction and blockade of activator protein-1
    • 19174156 1:CAS:528:DC%2BD1MXivVeht7s%3D
    • PH Park HS Kim XY Jin F Jin J Hur G Ko DH Sohn 2009 KB-34, a newly synthesized chalcone derivative, inhibits lipopolysaccharide-stimulated nitric oxide production in RAW 264.7 macrophages via heme oxygenase-1 induction and blockade of activator protein-1 Eur J Pharmacol 606 215 224 19174156 1:CAS:528:DC%2BD1MXivVeht7s%3D
    • (2009) Eur J Pharmacol , vol.606 , pp. 215-224
    • Park, P.H.1    Kim, H.S.2    Jin, X.Y.3    Jin, F.4    Hur, J.5    Ko, G.6    Sohn, D.H.7
  • 145
    • 57749105240 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of a series of tangeretin-derived chalcones
    • 19013795 1:CAS:528:DC%2BD1MXlvFGn
    • J Quintin J Desrivot S Thoret P Le Menez T Cresteil G Lewin 2009 Synthesis and biological evaluation of a series of tangeretin-derived chalcones Bioorg Med Chem Lett 19 167 169 19013795 1:CAS:528:DC%2BD1MXlvFGn
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 167-169
    • Quintin, J.1    Desrivot, J.2    Thoret, S.3    Le Menez, P.4    Cresteil, T.5    Lewin, G.6
  • 146
    • 65549144609 scopus 로고    scopus 로고
    • Mitochondria as targets for cancer therapy
    • 19123183 1:CAS:528:DC%2BD1MXhs1Sht7s%3D
    • SJ Ralph J Neuzil 2009 Mitochondria as targets for cancer therapy Mol Nutr Food Res 53 9 28 19123183 1:CAS:528:DC%2BD1MXhs1Sht7s%3D
    • (2009) Mol Nutr Food Res , vol.53 , pp. 9-28
    • Ralph, S.J.1    Neuzil, J.2
  • 147
    • 2142640813 scopus 로고    scopus 로고
    • Differential effects of synthesized 2′-oxygenated chalcone derivatives: Modulation of human cell cycle phase distribution
    • DOI 10.1016/j.bmc.2004.03.014, PII S0968089604001907
    • YK Rao SH Fang YM Tzeng 2004 Differential effects of synthesized 2′-oxygenated chalcone derivatives: modulation of human cell cycle phase distribution Bioorg Med Chem 12 2679 2686 15110849 1:CAS:528: DC%2BD2cXjtl2nur8%3D (Pubitemid 38542792)
    • (2004) Bioorganic and Medicinal Chemistry , vol.12 , Issue.10 , pp. 2679-2686
    • Rao, Y.K.1    Fang, S.-H.2    Tzeng, Y.-M.3
  • 148
    • 71849101913 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of 3′,4′,5′- trimethoxychalcone analogues as inhibitors of nitric oxide production and tumor cell proliferation
    • 19875299
    • YK Rao SH Fang YM Tzeng 2009 Synthesis and biological evaluation of 3′,4′,5′-trimethoxychalcone analogues as inhibitors of nitric oxide production and tumor cell proliferation Bioorg Med Chem 17 7909 7914 19875299
    • (2009) Bioorg Med Chem , vol.17 , pp. 7909-7914
    • Rao, Y.K.1    Fang, S.H.2    Tzeng, Y.M.3
  • 149
    • 77951043155 scopus 로고    scopus 로고
    • Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-kappaB in activated human mast cells: Suppression of tumor necrosis factor-alpha, interleukin (IL)-6, and IL-8
    • 20164300 1:CAS:528:DC%2BC3cXlsFKht7c%3D
    • Z Rasheed N Akhtar A Khan KA Khan TM Haqqi 2010 Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-kappaB in activated human mast cells: suppression of tumor necrosis factor-alpha, interleukin (IL)-6, and IL-8 J Pharmacol Exp Ther 333 354 363 20164300 1:CAS:528:DC%2BC3cXlsFKht7c%3D
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 354-363
    • Rasheed, Z.1    Akhtar, N.2    Khan, A.3    Khan, K.A.4    Haqqi, T.M.5
  • 150
    • 0029743633 scopus 로고    scopus 로고
    • Endocrine and paracrine hormones in the promotion, progression and recurrence of breast cancer
    • SE Reid MS Murthy M Kaufman EF Scanlon 1996 Endocrine and paracrine hormones in the promotion, progression and recurrence of breast cancer Br J Surg 83 1037 1046 8869300 1:STN:280:DyaK2s%2Fit12nsg%3D%3D (Pubitemid 26291203)
    • (1996) British Journal of Surgery , vol.83 , Issue.8 , pp. 1037-1046
    • Reid, S.E.1    Murthy, M.S.2    Kaufman, M.3    Scanlon, E.F.4
  • 151
    • 0036306766 scopus 로고    scopus 로고
    • The antioxidant activity of phloretin: The disclosure of a new antioxidant pharmacophore in flavonoids
    • DOI 10.1016/S0006-291X(02)00618-6, PII S0006291X02006186
    • BM Rezk GR Haenen WJ van der Vijgh A Bast 2002 The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids Biochem Biophys Res Commun 295 9 13 12083758 1:CAS:528:DC%2BD38Xksl2nu7Y%3D (Pubitemid 34743766)
    • (2002) Biochemical and Biophysical Research Communications , vol.295 , Issue.1 , pp. 9-13
    • Rezk, B.M.1    Haenen, G.R.M.M.2    Van Der Vijgh, W.J.F.3    Bast, A.4
  • 153
    • 25444495234 scopus 로고    scopus 로고
    • The chalcone butein from Rhus verniciflua Stokes inhibits clonogenic growth of human breast cancer cells co-cultured with fibroblasts
    • 15757513
    • M Samoszuk J Tan G Chorn 2005 The chalcone butein from Rhus verniciflua Stokes inhibits clonogenic growth of human breast cancer cells co-cultured with fibroblasts BMC Complement Altern Med 5 5 15757513
    • (2005) BMC Complement Altern Med , vol.5 , pp. 5
    • Samoszuk, M.1    Tan, J.2    Chorn, G.3
  • 154
    • 4143059348 scopus 로고    scopus 로고
    • Antiproliferative and antiangiogenic activities of genistein in human renal cell carcinoma
    • DOI 10.1016/j.urology.2004.03.045, PII S0090429504004170
    • H Sasamura A Takahashi J Yuan H Kitamura N Masumori N Miyao N Itoh T Tsukamoto 2004 Antiproliferative and antiangiogenic activities of genistein in human renal cell carcinoma Urology 64 389 393 15302513 (Pubitemid 39092489)
    • (2004) Urology , vol.64 , Issue.2 , pp. 389-393
    • Sasamura, H.1    Takahashi, A.2    Yuan, J.3    Kitamura, H.4    Masumori, N.5    Miyao, N.6    Itoh, N.7    Tsukamoto, T.8
  • 155
    • 49049110697 scopus 로고    scopus 로고
    • Structure-activity relationships of methoxychalcones as inducers of heme oxygenase-1
    • 18547064 1:CAS:528:DC%2BD1cXntVygu7s%3D
    • P Sawle BE Moulton M Jarzykowska CJ Green R Foresti IJ Fairlamb R Motterlini 2008 Structure-activity relationships of methoxychalcones as inducers of heme oxygenase-1 Chem Res Toxicol 21 1484 1494 18547064 1:CAS:528: DC%2BD1cXntVygu7s%3D
    • (2008) Chem Res Toxicol , vol.21 , pp. 1484-1494
    • Sawle, P.1    Moulton, B.E.2    Jarzykowska, M.3    Green, C.J.4    Foresti, R.5    Fairlamb, I.J.6    Motterlini, R.7
  • 156
    • 0037212056 scopus 로고    scopus 로고
    • Cytotoxic and inhibitory effects of 4,4′-dihydroxy chalcone (RVC-588) on proliferation of human leukemic HL-60 cells
    • DOI 10.1016/S0145-2126(02)00058-9, PII S0145212602000589
    • G Saydam HH Aydin F Sahin O Kucukoglu E Erciyas E Terzioglu F Buyukkececi SB Omay 2003 Cytotoxic and inhibitory effects of 4,4′-dihydroxy chalcone (RVC-588) on proliferation of human leukemic HL-60 cells Leuk Res 27 57 64 12479853 1:CAS:528:DC%2BD38XptlSqtbc%3D (Pubitemid 35449717)
    • (2003) Leukemia Research , vol.27 , Issue.1 , pp. 57-64
    • Saydam, G.1    Aydin, H.H.2    Sahin, F.3    Kucukoglu, O.4    Erciyas, E.5    Terzioglu, E.6    Buyukkececi, F.7    Omay, S.B.8
  • 157
    • 33646812944 scopus 로고    scopus 로고
    • Flavonoids and vitamin E reduce the release of the angiogenic peptide vascular endothelial growth factor from human tumor cells
    • R Schindler R Mentlein 2006 Flavonoids and vitamin E reduce the release of the angiogenic peptide vascular endothelial growth factor from human tumor cells J Nutr 136 1477 1482 16702307 1:CAS:528:DC%2BD28Xlt1WntLo%3D (Pubitemid 43765348)
    • (2006) Journal of Nutrition , vol.136 , Issue.6 , pp. 1477-1482
    • Schindler, R.1    Mentlein, R.2
  • 158
    • 36649009387 scopus 로고    scopus 로고
    • Chalcone arrests cell cycle progression and induces apoptosis through induction of mitochondrial pathway and inhibition of nuclear factor kappa B signalling in human bladder cancer cells
    • 17845507 1:CAS:528:DC%2BD2sXhtFWmurrP
    • KH Shen JK Chang YL Hsu PL Kuo 2007 Chalcone arrests cell cycle progression and induces apoptosis through induction of mitochondrial pathway and inhibition of nuclear factor kappa B signalling in human bladder cancer cells Basic Clin Pharmacol Toxicol 101 254 261 17845507 1:CAS:528:DC%2BD2sXhtFWmurrP
    • (2007) Basic Clin Pharmacol Toxicol , vol.101 , pp. 254-261
    • Shen, K.H.1    Chang, J.K.2    Hsu, Y.L.3    Kuo, P.L.4
  • 159
    • 14644410403 scopus 로고    scopus 로고
    • Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-κB: Implications for angioprevention and antiangiogenic therapy
    • DOI 10.1038/sj.onc.1208276
    • RP Singh S Dhanalakshmi C Agarwal R Agarwal 2005 Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy Oncogene 24 1188 1202 15558015 1:CAS:528:DC%2BD2MXhtFGqs7o%3D (Pubitemid 40313920)
    • (2005) Oncogene , vol.24 , Issue.7 , pp. 1188-1202
    • Singh, R.P.1    Dhanalakshmi, S.2    Agarwal, C.3    Agarwal, R.4
  • 160
    • 27644477094 scopus 로고    scopus 로고
    • Cancer chemoprevention: Scientific promise, clinical uncertainty
    • DOI 10.1038/ncponc0319, PII N0319
    • MB Sporn KT Liby 2005 Cancer chemoprevention: scientific promise, clinical uncertainty Nat Clin Pract Oncol 2 518 525 16205771 1:CAS:528:DC%2BD2MXhtFCrsb7E (Pubitemid 41553936)
    • (2005) Nature Clinical Practice Oncology , vol.2 , Issue.10 , pp. 518-525
    • Sporn, M.B.1    Liby, K.T.2
  • 161
    • 70949087763 scopus 로고    scopus 로고
    • Structure-activity relationship studies of chalcone leading to 3-hydroxy-4,3′,4′,5′-tetramethoxychalcone and its analogues as potent nuclear factor kappaB inhibitors and their anticancer activities
    • 19883086 1:CAS:528:DC%2BD1MXhtlCkur3I
    • B Srinivasan TE Johnson R Lad C Xing 2009 Structure-activity relationship studies of chalcone leading to 3-hydroxy-4,3′,4′,5′- tetramethoxychalcone and its analogues as potent nuclear factor kappaB inhibitors and their anticancer activities J Med Chem 52 7228 7235 19883086 1:CAS:528:DC%2BD1MXhtlCkur3I
    • (2009) J Med Chem , vol.52 , pp. 7228-7235
    • Srinivasan, B.1    Johnson, T.E.2    Lad, R.3    Xing, C.4
  • 163
    • 77955839687 scopus 로고    scopus 로고
    • Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism
    • Strathmann J (2010) Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism. FASEB J 24
    • (2010) FASEB J , vol.24
    • Strathmann, J.1
  • 165
    • 0030847426 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase: A novel approach to cancer prevention
    • 9349689 1:CAS:528:DyaK2sXntVKks7Y%3D
    • K Subbaramaiah D Zakim BB Weksler AJ Dannenberg 1997 Inhibition of cyclooxygenase: a novel approach to cancer prevention Proc Soc Exp Biol Med 216 201 210 9349689 1:CAS:528:DyaK2sXntVKks7Y%3D
    • (1997) Proc Soc Exp Biol Med , vol.216 , pp. 201-210
    • Subbaramaiah, K.1    Zakim, D.2    Weksler, B.B.3    Dannenberg, A.J.4
  • 167
    • 61749083799 scopus 로고    scopus 로고
    • Effects of the kava chalcone flavokawain A differ in bladder cancer cells with wild-type versus mutant p53
    • 1:CAS:528:DC%2BC3cXptVyqsrw%3D
    • Y Tang AR Simoneau J Xie B Shahandeh X Zi 2008 Effects of the kava chalcone flavokawain A differ in bladder cancer cells with wild-type versus mutant p53 Cancer Prev Res (Phila Pa) 1 439 451 1:CAS:528:DC%2BC3cXptVyqsrw%3D
    • (2008) Cancer Prev Res (Phila Pa) , vol.1 , pp. 439-451
    • Tang, Y.1    Simoneau, A.R.2    Xie, J.3    Shahandeh, B.4    Zi, X.5
  • 168
    • 77956113476 scopus 로고    scopus 로고
    • Flavokawain B, a kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth
    • Tang Y, Li X, Liu Z, Simoneau AR, Xie J, Zi X (2010) Flavokawain B, a kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth. Int J Cancer
    • (2010) Int J Cancer
    • Tang, Y.1    Li, X.2    Liu, Z.3    Simoneau, A.R.4    Xie, J.5    Zi, X.6
  • 169
    • 42749092258 scopus 로고    scopus 로고
    • TRAIL receptor-targeted therapeutics: Resistance mechanisms and strategies to avoid them
    • 18374623 1:CAS:528:DC%2BD1cXlslWqtbY%3D
    • A Thorburn K Behbakht H Ford 2008 TRAIL receptor-targeted therapeutics: resistance mechanisms and strategies to avoid them Drug Resist Updat 11 17 24 18374623 1:CAS:528:DC%2BD1cXlslWqtbY%3D
    • (2008) Drug Resist Updat , vol.11 , pp. 17-24
    • Thorburn, A.1    Behbakht, K.2    Ford, H.3
  • 171
    • 56749112002 scopus 로고    scopus 로고
    • Food as medicine: Potential therapeutic tendencies of plant derived polyphenolic compounds
    • 18712957
    • MF Ullah MW Khan 2008 Food as medicine: potential therapeutic tendencies of plant derived polyphenolic compounds Asian Pac J Cancer Prev 9 187 195 18712957
    • (2008) Asian Pac J Cancer Prev , vol.9 , pp. 187-195
    • Ullah, M.F.1    Khan, M.W.2
  • 172
    • 28044468215 scopus 로고    scopus 로고
    • Antiinvasive effect of xanthohumol, a prenylated chalcone present in hops (Humulus lupulus L.) and beer
    • DOI 10.1002/ijc.21249
    • B Vanhoecke L Derycke V Van Marck H Depypere D De Keukeleire M Bracke 2005 Antiinvasive effect of xanthohumol, a prenylated chalcone present in hops (Humulus lupulus L.) and beer Int J Cancer 117 889 895 15986430 1:CAS:528:DC%2BD2MXht1CntLbP (Pubitemid 41688562)
    • (2005) International Journal of Cancer , vol.117 , Issue.6 , pp. 889-895
    • Vanhoecke, B.1    Derycke, L.2    Van Marck, V.3    Depypere, H.4    De Keukeleire, D.5    Bracke, M.6
  • 173
    • 17444362645 scopus 로고    scopus 로고
    • The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase
    • DOI 10.1016/j.lfs.2004.12.014
    • Y Wang FL Chan S Chen LK Leung 2005 The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase Life Sci 77 39 51 15848217 1:CAS:528:DC%2BD2MXjsVersr0%3D (Pubitemid 40546375)
    • (2005) Life Sciences , vol.77 , Issue.1 , pp. 39-51
    • Wang, Y.1    Chan, F.L.2    Chen, S.3    Leung, L.K.4
  • 175
    • 0030770386 scopus 로고    scopus 로고
    • Aspirin use and potential mechanisms for colorectal cancer prevention
    • CS Williams W Smalley RN DuBois 1997 Aspirin use and potential mechanisms for colorectal cancer prevention J Clin Invest 100 1325 1329 9294096 1:CAS:528:DyaK2sXmt1Cqs7o%3D (Pubitemid 27425755)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.6 , pp. 1325-1329
    • Williams, C.S.1    Smalley, W.2    DuBois, R.N.3
  • 176
    • 67249152036 scopus 로고    scopus 로고
    • Effects of hydroxy safflor yellow A on blood vessel and mRNA expression with VEGF and bFGF of transplantation tumor with gastric adenocarcinoma cell line BGC-823 in nude mice
    • 19526794 1:CAS:528:DC%2BD1MXmtFejtL0%3D
    • S Xi Q Zhang H Xie L Liu C Liu X Gao J Zhang L Wu L Qian X Deng 2009 Effects of hydroxy safflor yellow A on blood vessel and mRNA expression with VEGF and bFGF of transplantation tumor with gastric adenocarcinoma cell line BGC-823 in nude mice Zhongguo Zhong Yao Za Zhi 34 605 610 19526794 1:CAS:528:DC%2BD1MXmtFejtL0%3D
    • (2009) Zhongguo Zhong Yao Za Zhi , vol.34 , pp. 605-610
    • Xi, S.1    Zhang, Q.2    Xie, H.3    Liu, L.4    Liu, C.5    Gao, X.6    Zhang, J.7    Wu, L.8    Qian, L.9    Deng, X.10
  • 179
    • 67649962635 scopus 로고    scopus 로고
    • Synthesis of a series of novel dihydroartemisinin derivatives containing a substituted chalcone with greater cytotoxic effects in leukemia cells
    • 19501507 1:CAS:528:DC%2BD1MXosVGlsr8%3D
    • X Yang W Wang J Tan D Song M Li D Liu Y Jing L Zhao 2009 Synthesis of a series of novel dihydroartemisinin derivatives containing a substituted chalcone with greater cytotoxic effects in leukemia cells Bioorg Med Chem Lett 19 4385 4388 19501507 1:CAS:528:DC%2BD1MXosVGlsr8%3D
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 4385-4388
    • Yang, X.1    Wang, W.2    Tan, J.3    Song, D.4    Li, M.5    Liu, D.6    Jing, Y.7    Zhao, L.8
  • 181
    • 20544458556 scopus 로고    scopus 로고
    • Induction of apoptosis in K562 human leukemia cells by 2′,4′- dihydroxy-6′-methoxy-3′,5′-dimethylchalcone
    • DOI 10.1016/j.leukres.2005.01.006, PII S0145212605000500
    • CL Ye F Qian DZ Wei YH Lu JW Liu 2005 Induction of apoptosis in K562 human leukemia cells by 2′,4′-dihydroxy-6′-methoxy-3′, 5′-dimethylchalcone Leuk Res 29 887 892 15978939 1:CAS:528: DC%2BD2MXlsFCksbY%3D (Pubitemid 40840716)
    • (2005) Leukemia Research , vol.29 , Issue.8 , pp. 887-892
    • Ye, C.-L.1    Qian, F.2    Wei, D.-Z.3    Lu, Y.-H.4    Liu, J.-W.5
  • 182
    • 58749093583 scopus 로고    scopus 로고
    • Dietary administration of the licorice flavonoid isoliquiritigenin deters the growth of MCF-7 cells overexpressing aromatase
    • 19065667 1:CAS:528:DC%2BD1MXhvFClsb4%3D
    • L Ye WM Gho FL Chan S Chen LK Leung 2009 Dietary administration of the licorice flavonoid isoliquiritigenin deters the growth of MCF-7 cells overexpressing aromatase Int J Cancer 124 1028 1036 19065667 1:CAS:528:DC%2BD1MXhvFClsb4%3D
    • (2009) Int J Cancer , vol.124 , pp. 1028-1036
    • Ye, L.1    Gho, W.M.2    Chan, F.L.3    Chen, S.4    Leung, L.K.5
  • 183
    • 0028336781 scopus 로고
    • Cytotoxic effect of butein on human colon adenocarcinoma cell proliferation
    • DOI 10.1016/0304-3835(94)90147-3
    • CC Yit NP Das 1994 Cytotoxic effect of butein on human colon adenocarcinoma cell proliferation Cancer Lett 82 65 72 8033070 1:CAS:528:DyaK2cXlt1CktL0%3D (Pubitemid 24211073)
    • (1994) Cancer Letters , vol.82 , Issue.1 , pp. 65-72
    • Yit, C.C.1    Das, N.P.2
  • 184
    • 70349306540 scopus 로고    scopus 로고
    • Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway
    • 19711916 1:CAS:528:DC%2BD1MXhtVGjtb3J
    • YT Yo GS Shieh KF Hsu CL Wu AL Shiau 2009 Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway J Agric Food Chem 57 8266 8273 19711916 1:CAS:528:DC%2BD1MXhtVGjtb3J
    • (2009) J Agric Food Chem , vol.57 , pp. 8266-8273
    • Yo, Y.T.1    Shieh, G.S.2    Hsu, K.F.3    Wu, C.L.4    Shiau, A.L.5
  • 185
    • 15844416174 scopus 로고    scopus 로고
    • Glycyrrhizae Radix attenuates peroxynitrite-induced renal oxidative damage through inhibition of protein nitration
    • DOI 10.1080/10715760400027888
    • T Yokozawa EJ Cho DY Rhyu N Shibahara K Aoyagi 2005 Glycyrrhizae Radix attenuates peroxynitrite-induced renal oxidative damage through inhibition of protein nitration Free Radic Res 39 203 211 15763968 1:CAS:528: DC%2BD2MXitVCmt74%3D (Pubitemid 40425742)
    • (2005) Free Radical Research , vol.39 , Issue.2 , pp. 203-211
    • Yokozawa, T.1    Cho, E.J.2    Rhyu, D.Y.3    Shibahara, N.4    Aoyagi, K.5
  • 186
    • 67349188370 scopus 로고    scopus 로고
    • Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells
    • 19568915 1:CAS:528:DC%2BD1cXht1yntr3F
    • T Yoshida M Horinaka M Takara M Tsuchihashi N Mukai M Wakada T Sakai 2008 Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells Environ Health Prev Med 13 281 287 19568915 1:CAS:528:DC%2BD1cXht1yntr3F
    • (2008) Environ Health Prev Med , vol.13 , pp. 281-287
    • Yoshida, T.1    Horinaka, M.2    Takara, M.3    Tsuchihashi, M.4    Mukai, N.5    Wakada, M.6    Sakai, T.7
  • 187
    • 21344465686 scopus 로고    scopus 로고
    • Induction of apoptosis by panduratin A isolated from Kaempferia pandurata in human colon cancer HT-29 cells
    • DOI 10.1055/s-2005-864149
    • JM Yun H Kwon H Mukhtar JK Hwang 2005 Induction of apoptosis by Panduratin A isolated from Kaempferia pandurata in human colon cancer HT-29 cells Planta Med 71 501 507 15971119 1:CAS:528:DC%2BD2MXlvFClurs%3D (Pubitemid 40910594)
    • (2005) Planta Medica , vol.71 , Issue.6 , pp. 501-507
    • Yun, J.-M.1    Kwon, H.2    Mukhtar, H.3    Hwang, J.-K.4
  • 188
    • 33745601961 scopus 로고    scopus 로고
    • Induction of apoptosis and cell cycle arrest by a chalcone panduratin A isolated from Kaempferia pandurata in androgen-independent human prostate cancer cells PC3 and DU145
    • DOI 10.1093/carcin/bgi348
    • JM Yun MH Kweon H Kwon JK Hwang H Mukhtar 2006 Induction of apoptosis and cell cycle arrest by a chalcone panduratin A isolated from Kaempferia pandurata in androgen-independent human prostate cancer cells PC3 and DU145 Carcinogenesis 27 1454 1464 16497706 1:CAS:528:DC%2BD28XmsVegtb0%3D (Pubitemid 43985420)
    • (2006) Carcinogenesis , vol.27 , Issue.7 , pp. 1454-1464
    • Yun, J.-M.1    Kweon, M.-H.2    Kwon, H.3    Hwang, J.-K.4    Mukhtar, H.5
  • 189
    • 14644437742 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAIL-induced apoptosis in cancer
    • DOI 10.1038/sj.cgt.7700792
    • L Zhang B Fang 2005 Mechanisms of resistance to TRAIL-induced apoptosis in cancer Cancer Gene Ther 12 228 237 15550937 1:CAS:528:DC%2BD2MXhtlahsLc%3D (Pubitemid 40315182)
    • (2005) Cancer Gene Therapy , vol.12 , Issue.3 , pp. 228-237
    • Zhang, L.1    Fang, B.2
  • 190
    • 44449141072 scopus 로고    scopus 로고
    • A novel anticancer effect of butein: Inhibition of invasion through the ERK1/2 and NF-kappa B signaling pathways in bladder cancer cells
    • 18472007 1:CAS:528:DC%2BD1cXms1WitL8%3D
    • L Zhang W Chen X Li 2008 A novel anticancer effect of butein: inhibition of invasion through the ERK1/2 and NF-kappa B signaling pathways in bladder cancer cells FEBS Lett 582 1821 1828 18472007 1:CAS:528:DC%2BD1cXms1WitL8%3D
    • (2008) FEBS Lett , vol.582 , pp. 1821-1828
    • Zhang, L.1    Chen, W.2    Li, X.3
  • 193
    • 17844405853 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor receptor signal pathway and antitumor activity of ON-III (2′,4′-dihydroxy-6′-methoxy- 3′,5′-dimethylchalcone), a component from Chinese herbal medicine
    • 15703376 1:CAS:528:DC%2BD2MXktFegsbw%3D
    • XF Zhu BF Xie JM Zhou GK Feng ZC Liu XY Wei FX Zhang MF Liu YX Zeng 2005 Blockade of vascular endothelial growth factor receptor signal pathway and antitumor activity of ON-III (2′,4′-dihydroxy-6′-methoxy- 3′,5′-dimethylchalcone), a component from Chinese herbal medicine Mol Pharmacol 67 1444 1450 15703376 1:CAS:528:DC%2BD2MXktFegsbw%3D
    • (2005) Mol Pharmacol , vol.67 , pp. 1444-1450
    • Zhu, X.F.1    Xie, B.F.2    Zhou, J.M.3    Feng, G.K.4    Liu, Z.C.5    Wei, X.Y.6    Zhang, F.X.7    Liu, M.F.8    Zeng, Y.X.9
  • 194
    • 17144400791 scopus 로고    scopus 로고
    • Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and tumor growth in mice
    • X Zi AR Simoneau 2005 Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice Cancer Res 65 3479 3486 15833884 1:CAS:528: DC%2BD2MXjt1yrt7o%3D (Pubitemid 40524635)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3479-3486
    • Zi, X.1    Simoneau, A.R.2
  • 195
    • 70350776722 scopus 로고    scopus 로고
    • Cytotoxic activity of isoliquiritigenin towards CCRF-CEM leukemia cells and its effect on DNA damage
    • 19291608 1:CAS:528:DC%2BD1MXhtFCjsbzP
    • Y Zu X Liu Y Fu X Shi N Wu L Yao T Efferth 2009 Cytotoxic activity of isoliquiritigenin towards CCRF-CEM leukemia cells and its effect on DNA damage Planta Med 75 1134 1140 19291608 1:CAS:528:DC%2BD1MXhtFCjsbzP
    • (2009) Planta Med , vol.75 , pp. 1134-1140
    • Zu, Y.1    Liu, X.2    Fu, Y.3    Shi, X.4    Wu, N.5    Yao, L.6    Efferth, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.