Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; inhibition of endothelial cell survival and proliferation by targeting phosphatidylinositol 3′-kinase activity

Cancer Research

Volumn 64, Issue 21, 2004, Pages 7936-7946

  Bagli, Eleni ^a   Stefaniotou, Maria ^a   Morbidelli, Lucia ^b   Ziche, Marina ^b   Psillas, Konstantinos ^a   Murphy, Carol ^c   Fotsis, Theodore ^a,c  

^a UNIVERSITY OF IOANNINA   (Greece)

^b UNIVERSITY OF SIENA   (Italy)

^c INSTITUTE OF COMPUTER SCIENCE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

FLAVONOID; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LUTEOLIN; PHOSPHATIDYLINOSITOL 3 KINASE; S6 KINASE; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CORNEA; DRUG ACTIVITY; DRUG EFFECT; EMBRYO; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VIVO CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RABBIT; SIGNAL TRANSDUCTION; TUMOR VASCULARIZATION; UMBILICAL VEIN;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANGIOGENESIS INHIBITORS; ANIMALS; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIAL CELLS; FEMALE; HUMANS; LUTEOLIN; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASMS, EXPERIMENTAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RABBITS; RIBOSOMAL PROTEIN S6 KINASES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 7444272077     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-3104     Document Type: Article

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