Studies of structure-activity relationship on plant polyphenol-induced suppression of human liver cancer cells

Cancer Chemotherapy and Pharmacology

Volumn 63, Issue 6, 2009, Pages 1007-1016

  Loa, Jacky ^a   Chow, Pierce ^a   Zhang, Kai ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

2,2' Dihydroxychalcone; Anticancer activity: apoptosis; G2 M arrest; Liver cancer; Plant polyphenols

Indexed keywords

2 HYDROXY 2, 4,4' TRIMETHOXYCHALCONE; 2' HYDROXY 2 METHOXYCHALCONE; 2' HYDROXY 2,4 METHOXYCHALCONE; 2' HYDROXY 4 METHYLCHALCONE; 2' HYDROXY 4,4',6' TRIMETHOXYCHALCONE; 2' HYDROXYLCHALCONE; 2',5' DIHYDROXYCHALCONE; 2'4 DIMETHOXYCHALCONE; 2, 4' DIHYDROXYCHALCONE; 2,2' DIHYDROXY 3 METHOXYCHALCONE; 2,2' DIHYDROXYCHALCONE; 2,2',4' TRIHYDROXYCHALCONE; 2,4,2',5' TETRAMETHOXYCHALCONE; 3,2' DIHYDROXYCHALCONE; 3,4,2'4' TETRAHYDROXYCHALCONE; 4 HYDROXYFLAVONE; 4,2',5' TRIMETHOXYCHALCONE; CHALCONE DERIVATIVE; CHROMONE DERIVATIVE; COUMARIN DERIVATIVE; DNA FRAGMENT; FISETIN; FLAVANONE DERIVATIVE; FLAVONE DERIVATIVE; GENISTEIN; ISOFLAVONE DERIVATIVE; KAEMPFEROL; LUTEOLIN; QUERCETIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; DRUG STRUCTURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDROXYLATION; IC 50; LIVER CANCER; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CHALCONES; FLAVONOIDS; HUMANS; INHIBITORY CONCENTRATION 50; LIVER NEOPLASMS; MOLECULAR STRUCTURE; PHENOLS; PLANT EXTRACTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 63949084699     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0802-y     Document Type: Article

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