Modification of the cysteine residues in IκBα kinase and NF-κB (p65) by xanthohumol leads to suppression of NF-κB-regulated gene products and potentiation of apoptosis in leukemia cells

Blood

Volumn 113, Issue 9, 2009, Pages 2003-2013

  Harikumar, Kuzhuvelil B ^a   Kunnumakkara, Ajaikumar B ^a   Ahn, Kwang S ^a   Anand, Preetha ^a   Krishnan, Sunil ^a   Guha, Sushovan ^a   Aggarwal, Bharat B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYCLIN D1; CYSTEINE; DNA; GENE PRODUCT; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; MYC PROTEIN; PROTEIN BCL XL; SERINE; SURVIVIN; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR; X LINKED INHIBITOR OF APOPTOSIS; XANTHOHUMOL;

APOPTOSIS; ARTICLE; CORRELATION ANALYSIS; DOWN REGULATION; DRUG INHIBITION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MUTATION; MYELOMA CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; REPORTER GENE;

EID: 61949193344     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-04-151944     Document Type: Article

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