Chalcones: An update on cytotoxic and chemoprotective properties

Current Medicinal Chemistry

Volumn 12, Issue 4, 2005, Pages 483-499

  Go, M L ^a   Wu, X ^a   Liu, X L ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Chalcones; Chemoprotective; Cytotoxic; Organic synthesis; Physicochemical characterisation

Indexed keywords

2 CHLORO 2',5' DIHYDROCHALCONE; 2' HYDROXYCHALCONE; 2',4' DIHYDROXYCHALCONE; ALPHA METHYLCHALCONE; ANGIOGENESIS INHIBITOR; ANTIANDROGEN; ANTIMITOTIC AGENT; CHALCONE; CHALCONE DERIVATIVE; CHRYSIN; CYTOCHROME P450 1A; DERRICIN; DIHYDROCHALCONE; DRUG METABOLIZING ENZYME; EPOXIDE HYDROLASE; ESTROGEN RECEPTOR; GLUCURONOSYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HYDROXYCHALCONE; LICOCHALCONE A; LONCHOCARPIN; LOW DENSITY LIPOPROTEIN; NARINGENIN; PHLORETIN; PLANT EXTRACT; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHOHUMOL; ANTIESTROGEN; ANTINEOPLASTIC AGENT; ANTIOXIDANT; ENZYME INHIBITOR; NITRIC OXIDE; SULFUR DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CARCINOGENESIS; CATALYSIS; CELL CYCLE PHASE; CLAISEN CONDENSATION; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CYCLIZATION; CYTOTOXICITY; DRUG DESIGN; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; LEUKEMIA CELL LINE; LIPOPHILICITY; METASTASIS INHIBITION; METHODOLOGY; REVIEW; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; SUZUKI REACTION; TUMOR CELL LINE; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; HUMAN; SYNTHESIS;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; CELL LINE, TUMOR; CHALCONES; ENZYME INHIBITORS; ESTROGEN ANTAGONISTS; HUMANS; NITRIC OXIDE; SULFUR COMPOUNDS;

EID: 20144367578     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867053363153     Document Type: Review

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