Synthesis and biological evaluation of simple methoxylated chalcones as anticancer, anti-inflammatory and antioxidant agents

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 3, 2010, Pages 1364-1370

  Bandgar, Babasaheb P ^a,b   Gawande, Shrikant S ^b   Bodade, Ragini G ^b   Totre, Jalinder V ^c   Khobragade, Chandrahas N ^b  

^a SOLAPUR UNIVERSITY   (India)

^b SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY   (India)

^c Hebrew Universty of Jerusalem   (Israel)

Author keywords

Anti inflammatory activity; Anticancer activity; Antioxidant activity; Chalcones; Cytotoxicity

Indexed keywords

1 (2,4 DICHLOROPHENYL) 3 (2,4 DIMETHOXYPHENYL)PROPENONE; 1 (4 BROMOPHENYL) 3 (2,4 DIMETHOXYPHENYL)PROPENONE; 1 PHENYL 3 (3,4,5 TRIMETHOXYPHENYL)PROPENONE; 1,1 DIPHENYL 2 PICRYLHYDRAZYL; 3 (2,4 DIMETHOXYPHENYL) 1 (4 METHOXYPHENYL)PROPENONE; 3 (2,4 DIMETHOXYPHENYL) 1 (4 NITROPHENYL)PROPENONE; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CHALCONE DERIVATIVE; FLAVOPIRIDOL; GEMCITABINE; INTERLEUKIN 6; SCAVENGER; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CLAISEN CONDENSATION; CYTOTOXICITY; DRUG BIOAVAILABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROMETRY; INHIBITION KINETICS; MASS SPECTROMETRY; MOLECULAR WEIGHT; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CELL LINE, TUMOR; CHALCONES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 75149145989     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.11.066     Document Type: Article

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