Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

Science

Volumn 286, Issue 5443, 1999, Pages 1374-1377

  Pagès, Gilles ^a   Guérin, Sandrine ^b   Grall, Dominique ^a   Bonino, Frédéric ^a   Smith, Austin ^c   Anjuere, Fabienne ^b   Auberger, Patrick ^b   Pouysségur, Jacques ^a  

^a CENTRE ANTOINE LACASSAGNE   (France)

^b INSERM   (France)

^c Centre for Genome Research   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; THYMOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD3; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; DNA; ENZYME ACTIVATION; GENE TARGETING; ISOENZYMES; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTE SUBSETS; TETRADECANOYLPHORBOL ACETATE; THYMUS GLAND;

EID: 17144458301     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.286.5443.1374     Document Type: Article

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26. We thank E. Delaney and J. Ure for embryonic stem cell manipulation and chimera production and L. Anderson and staff for animal husbandry. Supported by grants from the Centre National de la Recherche Scientifique (CNRS), l'Université de Nice Sophia-Antipolis, le Ministère de la Recherche (grant ACC-SV9), la Ligue Nationale et Départementale de Lutte Contre le Cancer, l'Association pour la Recherche contre le Cancer (ARC), the Groupement des Entreprises Françaises et Monégasques dans la Lutte contre le Cancer (GEFLUC), and the European Community (contract B104-CT97-2071). Additional support was obtained from INSERM (P.A.) and the UK Biotechnology and Biological Sciences Research Council (A.S.).