Licochalcone a inhibits the growth of colon carcinoma and attenuates cisplatin-induced toxicity without a loss of chemotherapeutic efficacy in mice

Basic and Clinical Pharmacology and Toxicology

Volumn 103, Issue 1, 2008, Pages 48-54

  Lee, Chang Ki ^a,b   Son, Seung Hwa ^a   Park, Kwang Kyun ^a,b   Park, Jung Han Yoon ^c   Lim, Soon Sung ^c   Kim, Sook Hyang ^d   Chung, Won Yoon ^a,b  

^a Yonsei University College of Dentistry   (South Korea)

^b Yonsei University   (South Korea)

^c Hallym University   (South Korea)

^d Hanseo University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; GLUTATHIONE; LICOCHALCONE A; NITRIC OXIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL PROLIFERATION; COLON CARCINOMA; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DNA SYNTHESIS; DOSE RESPONSE; DRUG EFFICACY; KIDNEY INJURY; LIPID PEROXIDATION; LIVER INJURY; MALE; MONOTHERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; UREA NITROGEN BLOOD LEVEL;

ADMINISTRATION, ORAL; ALANINE TRANSAMINASE; ANIMALS; ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; BLOOD UREA NITROGEN; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHALCONES; CISPLATIN; COLONIC NEOPLASMS; CREATININE; DRUG THERAPY, COMBINATION; GLUTATHIONE; KIDNEY; LIPID PEROXIDATION; LIVER; MALE; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; NITRIC OXIDE; OXIDATIVE STRESS; TRANSPLANTATION, HETEROLOGOUS;

MURINAE; MUS;

EID: 45749128172     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2008.00238.x     Document Type: Article

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