Chalcone inhibits the activation of NF-κB and STAT3 in endothelial cells via endogenous electrophile

Life Sciences

Volumn 80, Issue 15, 2007, Pages 1420-1430

  Liu, Yen Chin ^a   Hsieh, Chia Wen ^a   Wu, Chun Ching ^a   Wung, Being Sun ^a  

^a NATIONAL CHIAYI UNIVERSITY   (Taiwan)

Author keywords

Chalcone; Electrophile; Glutathione; ICAM 1; NF B; STAT3

Indexed keywords

ACETYLCYSTEINE; BUTHIONINE SULFOXIMINE; CARBONYL DERIVATIVE; CHALCONE; CROTONALDEHYDE; CURCUMIN; CYANIDIN; FLAVONOID; GLUTATHIONE; HEME OXYGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LUCIFERASE; QUERCETIN; STAT3 PROTEIN; SYNAPTOTAGMIN I; THIOREDOXIN REDUCTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL ADHESION; CELL ASSAY; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG EXPOSURE; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR MIMICRY; NONHUMAN; PROMOTER REGION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, NORTHERN; BLOTTING, WESTERN; CATTLE; CELL ADHESION MOLECULES; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; CHALCONE; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; GLUTATHIONE; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LUCIFERASES; MONOCYTES; NF-KAPPA B; PLASMIDS; RNA; STAT3 TRANSCRIPTION FACTOR; TRANSFECTION;

EID: 33847633373     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.12.040     Document Type: Article

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