Chalcone derivatives antagonize interactions between the human oncoprotein MDM2 and p53

Biochemistry

Volumn 40, Issue 2, 2001, Pages 336-344

  Stoll, R ^a   Renner, C ^a   Hansen, S ^b   Palme, S ^b   Klein, C ^b   Belling, A ^a   Zeslawski, W ^a   Kamionka, M ^a   Rehm, T ^a   Muhlhahn P ^a   Schumacher, R ^b   Hesse, F ^b   Kaluza, B ^b   Voelter, W ^c   Engh, R A ^a,b   Holak, T A ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b ROCHE DIAGNOSTICS GMBH   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHALCONE DERIVATIVE; PROTEIN MDM2; PROTEIN P53;

ARTICLE; BINDING KINETICS; COMPLEX FORMATION; HUMAN; MOLECULAR INTERACTION; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; CHALCONE; DNA; HUMANS; KINETICS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEAR PROTEINS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; TRYPTOPHAN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035895350     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi000930v     Document Type: Article

References (40)