Synthesis and biological evaluation of 3′,4′,5′-trimethoxychalcone analogues as inhibitors of nitric oxide production and tumor cell proliferation

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 23, 2009, Pages 7909-7914

  Rao, Yerra Koteswara ^a   Fang, Shih Hua ^b   Tzeng, Yew Min ^a  

^a CHAOYANG UNIVERSITY OF TECHNOLOGY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY OF SPORT   (Taiwan)

Author keywords

3 ,4 ,5 Trimethoxychalcone analogues; Nitric oxide; Synthesis; Tumor cell proliferation

Indexed keywords

2 HYDROXY 3,3',4',5' TETRAMETHOXYCHALCONE; 2,3',4,4',5,5' HEXAMETHOXYCHALCONE; 2,3,3',4',5' PENTAMETHOXYCHALCONE; 3 FORMYL 3',4',5' TRIMETHOXYCHALCONE; 3 HYDROXY 3',4,4',5' TETRAMETHOXYCHALCONE; 3,3',4',5' TETRAMETHOXYCHALCONE; 3,3',4,4',5' PENTAMETHOXYCHALCONE; 3,3',4,4',5,5' HEXAMETHOXYCHALCONE; 3,4 DIHYDROXY 3',4',5' TRIMETHOXYCHALCONE; 4 HYDROXY 3,3',4',5' TETRAMETHOXYCHALCONE; CHALCONE DERIVATIVE; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; NITRIC OXIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MACROPHAGE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CHALCONES; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MACROPHAGE ACTIVATION; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; NITRIC OXIDE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 71849101913     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.10.022     Document Type: Article

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