Effects of hydroxy safflor yellow A on blood vessel and mRNA expression with VEGF and bFGF of transplantation tumor with gastric adenocarcinoma cell line BGC-823 in nude mice

Zhongguo Zhongyao Zazhi

Volumn 34, Issue 5, 2009, Pages 605-610

  Xi, Shengyan ^a   Zhang, Qian ^a   Xie, Hua ^a   Liu, Lintao ^a   Liu, Chaoyang ^b   Gao, Xuemin ^a   Zhang, Jianjun ^a   Wu, Likun ^a   Qian, Lili ^a   Deng, Xiaoying ^a  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b CANCER HOSPITAL   (China)

Author keywords

bFGF; BGC 823 transplantation tumor; Hydroxy safflor yellow A; Nude mice; Tumor angiogenesis; VEGF

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CYCLOPHOSPHAMIDE; HYDROXY SAFFLOR YELLOW A; MESSENGER RNA; SAFFLOWER EXTRACT; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER TRANSPLANTATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG MEGADOSE; LOW DRUG DOSE; MOUSE; NONHUMAN; STOMACH ADENOCARCINOMA; TUMOR VASCULARIZATION; TUMOR VOLUME;

ADENOCARCINOMA; ANGIOGENESIS INHIBITORS; ANIMALS; BLOOD VESSELS; CELL LINE, TUMOR; CHALCONE; DRUGS, CHINESE HERBAL; FEMALE; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; QUINONES; RANDOM ALLOCATION; STOMACH NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 67249152036     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Bhat T A, Singh R P. Tumor angiogenesis-A potential target in cancer chemoprevention[J]. Food Chem Toxicol,2008,46(4):1334.
2. Parkin D M. Global cancer statistics in the year 2000[J]. Lancet Oncol,2001,2:533.
3. Carmeliet P, Jain R K. Angiogenesis in cancer and other diseases [J]. Nature,2000,407(6801):249.
4. Kragh M, Hjarnaa P J, Bramm E, et al. In vivo chamber angiogenesis assay: an optimized Matrigel plug assay for fast assessment of anti-angiogenic activity[J]. Int J Oncol,2003,22(2):305.
5. Hamanol Y, Sugimotol H, Soubasakosl MA, et al. Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression[J]. Cancer Res,2004,64(5):1570.
6. Jain R K. Molecular regulation of vessel maturation[J]. Nat Med,2003,9(6):685.
7. Jiang Xinnong, Couchman J R. Perlecan and tumor angiogenesis[J]. J Histochem Cytochem,2003,51(11):1393.
8. Ferrara N. Vascular endothelial growth factor as a target for anticancer therapy[J]. Oncologist,2004,1:2.
9. Sohn Y D, Lim H J, Hwang K C, et al. A novel recombinant basic fibroblast growth factor and its secretion[J]. Biochem Biophys Res Commun,2001,284(4):931.