메뉴 건너뛰기




Volumn 1807, Issue 6, 2011, Pages 697-706

Bioactive food components, cancer cell growth limitation and reversal of glycolytic metabolism

Author keywords

B vitamin; Energy metabolism; Folate; Metabolic reprogramming; Mitochondria; Nutrition

Indexed keywords

FOLIC ACID; GLUCOSE; GLUTAMINE; GLYCOLYTIC ENZYME; GROWTH FACTOR; OMEGA 3 FATTY ACID; OXYGEN; POLYPHENOL; RETINOL; VITAMIN B GROUP;

EID: 79953689833     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2010.08.007     Document Type: Review
Times cited : (23)

References (181)
  • 2
    • 40349105880 scopus 로고    scopus 로고
    • Metabolic syndrome, hyperinsulinemia, and colon cancer: A review
    • E. Giovannucci Metabolic syndrome, hyperinsulinemia, and colon cancer: a review Am. J. Clin. Nutr. 86 2007 s836 842
    • (2007) Am. J. Clin. Nutr. , vol.86 , pp. 836-842
    • Giovannucci, E.1
  • 3
    • 0035295772 scopus 로고    scopus 로고
    • Epidemiology of breast cancer
    • DOI 10.1016/S1470-2045(00)00254-0, PII S1470204500002540
    • T.J. Key, P.K. Verkasalo, and E. Banks Epidemiology of breast cancer Lancet Oncol. 2 2001 133 140 (Pubitemid 33585924)
    • (2001) Lancet Oncology , vol.2 , Issue.3 , pp. 133-140
    • Key, T.J.1    Verkasalo, P.K.2    Banks, E.3
  • 4
    • 0005313671 scopus 로고    scopus 로고
    • IARC International Agency for Research on Cancer Lyon
    • IARC Weight Control and Physical Activity 2002 International Agency for Research on Cancer Lyon
    • (2002) Weight Control and Physical Activity
  • 6
    • 0010607277 scopus 로고
    • The effect of vitamin e and beta carotene on the incidence of lung cancer and other cancers in male smokers
    • The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group, The New England journal of medicine 330 (1994) 1029-1035.
    • (1994) The New England Journal of Medicine , vol.330 , pp. 1029-1035
  • 16
    • 77951923949 scopus 로고    scopus 로고
    • Mitochondrial control of caspase-dependent and -independent cell death
    • L.A. Pradelli, M. Beneteau, and J.E. Ricci Mitochondrial control of caspase-dependent and -independent cell death Cell. Mol. Life Sci. 67 2010 1589 1597
    • (2010) Cell. Mol. Life Sci. , vol.67 , pp. 1589-1597
    • Pradelli, L.A.1    Beneteau, M.2    Ricci, J.E.3
  • 17
    • 65549144609 scopus 로고    scopus 로고
    • Mitochondria as targets for cancer therapy
    • S.J. Ralph, and J. Neuzil Mitochondria as targets for cancer therapy Mol. Nutr. Food Res. 53 2009 9 28
    • (2009) Mol. Nutr. Food Res. , vol.53 , pp. 9-28
    • Ralph, S.J.1    Neuzil, J.2
  • 19
    • 77953131908 scopus 로고    scopus 로고
    • Targeting mitochondria for cancer therapy
    • S. Fulda, L. Galluzzi, and G. Kroemer Targeting mitochondria for cancer therapy Nat. rev. 9 2010 447 464
    • (2010) Nat. Rev. , vol.9 , pp. 447-464
    • Fulda, S.1    Galluzzi, L.2    Kroemer, G.3
  • 21
    • 11444261260 scopus 로고    scopus 로고
    • Energy boost: The Warburg effect returns in a new theory of cancer
    • K. Garber Energy boost: the Warburg effect returns in a new theory of cancer J. Natl Cancer Inst. 96 2004 1805 1806 (Pubitemid 40081310)
    • (2004) Journal of the National Cancer Institute , vol.96 , Issue.24 , pp. 1805-1806
    • Garber, K.1
  • 22
    • 77649183649 scopus 로고    scopus 로고
    • Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger
    • S.J. Ralph, S. Rodriguez-Enriquez, J. Neuzil, and R. Moreno-Sanchez Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger Mol. Aspects Med. 31 2010 29 59
    • (2010) Mol. Aspects Med. , vol.31 , pp. 29-59
    • Ralph, S.J.1    Rodriguez-Enriquez, S.2    Neuzil, J.3    Moreno-Sanchez, R.4
  • 24
    • 56749176442 scopus 로고    scopus 로고
    • LKB1; Linking cell structure and tumor suppression
    • A.F. Hezel, and N. Bardeesy LKB1; linking cell structure and tumor suppression Oncogene 27 2008 6908 6919
    • (2008) Oncogene , vol.27 , pp. 6908-6919
    • Hezel, A.F.1    Bardeesy, N.2
  • 25
    • 33644614520 scopus 로고    scopus 로고
    • HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
    • J.W. Kim, I. Tchernyshyov, G.L. Semenza, and C.V. Dang HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia Cell Metab. 3 2006 177 185
    • (2006) Cell Metab. , vol.3 , pp. 177-185
    • Kim, J.W.1    Tchernyshyov, I.2    Semenza, G.L.3    Dang, C.V.4
  • 26
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • I. Papandreou, R.A. Cairns, L. Fontana, A.L. Lim, and N.C. Denko HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption Cell Metab. 3 2006 187 197
    • (2006) Cell Metab. , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 28
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
    • R.J. DeBerardinis, J.J. Lum, G. Hatzivassiliou, and C.B. Thompson The biology of cancer: metabolic reprogramming fuels cell growth and proliferation Cell Metab. 7 2008 11 20
    • (2008) Cell Metab. , vol.7 , pp. 11-20
    • Deberardinis, R.J.1    Lum, J.J.2    Hatzivassiliou, G.3    Thompson, C.B.4
  • 29
    • 52649107626 scopus 로고    scopus 로고
    • Cancer cell metabolism: Warburg and beyond
    • P.P. Hsu, and D.M. Sabatini Cancer cell metabolism: Warburg and beyond Cell 134 2008 703 707
    • (2008) Cell , vol.134 , pp. 703-707
    • Hsu, P.P.1    Sabatini, D.M.2
  • 30
    • 44449147036 scopus 로고    scopus 로고
    • Tumor Cell Metabolism: Cancer's Achilles' Heel
    • DOI 10.1016/j.ccr.2008.05.005, PII S1535610808001608
    • G. Kroemer, and J. Pouyssegur Tumor cell metabolism: cancer's Achilles' heel Cancer Cell 13 2008 472 482 (Pubitemid 351766797)
    • (2008) Cancer Cell , vol.13 , Issue.6 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 31
    • 69949124867 scopus 로고    scopus 로고
    • Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells
    • O. Feron Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells Radiother. Oncol. 92 2009 329 333
    • (2009) Radiother. Oncol. , vol.92 , pp. 329-333
    • Feron, O.1
  • 32
    • 60549083256 scopus 로고    scopus 로고
    • Regulation of cancer cell metabolism by hypoxia-inducible factor 1
    • G.L. Semenza Regulation of cancer cell metabolism by hypoxia-inducible factor 1 Semin. Cancer Biol. 19 2009 12 16
    • (2009) Semin. Cancer Biol. , vol.19 , pp. 12-16
    • Semenza, G.L.1
  • 35
    • 23044456402 scopus 로고    scopus 로고
    • 2-Deoxyglucose as an energy restriction mimetic agent: Effects on mammary carcinogenesis and on mammary tumor cell growth in vitro
    • DOI 10.1158/0008-5472.CAN-05-0453
    • Z. Zhu, W. Jiang, J.N. McGinley, and H.J. Thompson 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro Cancer Res. 65 2005 7023 7030 (Pubitemid 41060743)
    • (2005) Cancer Research , vol.65 , Issue.15 , pp. 7023-7030
    • Zhu, Z.1    Jiang, W.2    McGinley, J.N.3    Thompson, H.J.4
  • 36
    • 33746879141 scopus 로고    scopus 로고
    • Glycolysis inhibition for anticancer treatment
    • DOI 10.1038/sj.onc.1209597, PII 1209597
    • H. Pelicano, D.S. Martin, R.H. Xu, and P. Huang Glycolysis inhibition for anticancer treatment Oncogene 25 2006 4633 4646 (Pubitemid 44187614)
    • (2006) Oncogene , vol.25 , Issue.34 , pp. 4633-4646
    • Pelicano, H.1    Martin, D.S.2    Xu, R.-H.3    Huang, P.4
  • 37
    • 34547785566 scopus 로고    scopus 로고
    • Targeting mitochondria in the treatment of human cancer: A coordinated attack against cancer cell energy metabolism and signalling
    • DOI 10.1517/14728222.11.8.1055
    • H. Hagland, J. Nikolaisen, L.I. Hodneland, B.T. Gjertsen, O. Bruserud, and K.J. Tronstad Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling Expert Opin. Ther. Targets 11 2007 1055 1069 (Pubitemid 47232621)
    • (2007) Expert Opinion on Therapeutic Targets , vol.11 , Issue.8 , pp. 1055-1069
    • Hagland, H.1    Nikolaisen, J.2    Hodneland, L.I.3    Gjertsen, B.T.4    Bruserud, O.5    Tronstad, K.J.6
  • 38
    • 34249945104 scopus 로고    scopus 로고
    • The cancer cell's 'power plants' as promising therapeutic targets: An overview
    • DOI 10.1007/s10863-007-9070-5, The Cancer Cell's Power Plants as Promising Therapeutic Targets
    • P.L. Pedersen The cancer cell's "power plants" as promising therapeutic targets: an overview J. Bioenerg. Biomembr. 39 2007 1 12 (Pubitemid 46877182)
    • (2007) Journal of Bioenergetics and Biomembranes , vol.39 , Issue.1 , pp. 1-12
    • Pedersen, P.L.1
  • 39
    • 32244448778 scopus 로고    scopus 로고
    • Targeting apoptosis with dietary bioactive agents
    • K.R. Martin Targeting apoptosis with dietary bioactive agents Experimental Biology and Medicine 231 2006 Maywood N.J 117 129 (Pubitemid 43213448)
    • (2006) Experimental Biology and Medicine , vol.231 , Issue.2 , pp. 117-129
    • Martin, K.R.1
  • 44
    • 0026651085 scopus 로고
    • Wine, alcohol, platelets, and the French paradox for coronary heart disease
    • S. Renaud, and M. de Lorgeril Wine, alcohol, platelets, and the French paradox for coronary heart disease Lancet 339 1992 1523 1526
    • (1992) Lancet , vol.339 , pp. 1523-1526
    • Renaud, S.1    De Lorgeril, M.2
  • 47
    • 57749170979 scopus 로고    scopus 로고
    • Chemopreventive potential of resveratrol in mouse skin tumors through regulation of mitochondrial and PI3K/AKT signaling pathways
    • P. Roy, N. Kalra, S. Prasad, J. George, and Y. Shukla Chemopreventive potential of resveratrol in mouse skin tumors through regulation of mitochondrial and PI3K/AKT signaling pathways Pharm. Res. 26 2009 211 217
    • (2009) Pharm. Res. , vol.26 , pp. 211-217
    • Roy, P.1    Kalra, N.2    Prasad, S.3    George, J.4    Shukla, Y.5
  • 49
    • 67650297506 scopus 로고    scopus 로고
    • Cancer prevention and treatment with resveratrol: From rodent studies to clinical trials
    • A. Bishayee Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials Cancer prev. res. (Philadelphia, Pa 2 2009 409 418
    • (2009) Cancer Prev. Res. (Philadelphia, Pa , vol.2 , pp. 409-418
    • Bishayee, A.1
  • 50
    • 77956165198 scopus 로고    scopus 로고
    • Growth-stimulatory effect of resveratrol in human cancer cells
    • M. Fukui, N. Yamabe, K.S. Kang, and B.T. Zhu Growth-stimulatory effect of resveratrol in human cancer cells Mol. Carcinog. 49 2010 750 759
    • (2010) Mol. Carcinog. , vol.49 , pp. 750-759
    • Fukui, M.1    Yamabe, N.2    Kang, K.S.3    Zhu, B.T.4
  • 51
    • 20044383992 scopus 로고    scopus 로고
    • Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation
    • DOI 10.1038/sj.ijo.0802926
    • S. Klaus, S. Pultz, C. Thone-Reineke, and S. Wolfram Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation Int. J. Obes. 29 2005 2005 615 623 (Pubitemid 40769483)
    • (2005) International Journal of Obesity , vol.29 , Issue.6 , pp. 615-623
    • Klaus, S.1    Pultz, S.2    Thone-Reineke, C.3    Wolfram, S.4
  • 52
    • 35348914727 scopus 로고    scopus 로고
    • Effects of green tea and EGCG on cardiovascular and metabolic health
    • S-388 S
    • S. Wolfram Effects of green tea and EGCG on cardiovascular and metabolic health J. Am. Coll. Nutr. 26 2007 373 S 388 S
    • (2007) J. Am. Coll. Nutr. , vol.26 , pp. 373
    • Wolfram, S.1
  • 53
    • 77949702385 scopus 로고    scopus 로고
    • Green tea polyphenols prevent UV-induced immunosuppression by rapid repair of DNA damage and enhancement of nucleotide excision repair genes
    • S.K. Katiyar, M. Vaid, H. van Steeg, and S.M. Meeran Green tea polyphenols prevent UV-induced immunosuppression by rapid repair of DNA damage and enhancement of nucleotide excision repair genes Cancer prev. res. (Philadelphia, Pa 3 2010 179 189
    • (2010) Cancer Prev. Res. (Philadelphia, Pa , vol.3 , pp. 179-189
    • Katiyar, S.K.1    Vaid, M.2    Van Steeg, H.3    Meeran, S.M.4
  • 55
    • 0344247741 scopus 로고    scopus 로고
    • New insights into the metastasis-associated 67 kD laminin receptor
    • DOI 10.1002/(SICI)1097-4644(19971101)67:2<155::AID-JCB1>3.0.CO;2-W
    • S. Menard, V. Castronovo, E. Tagliabue, and M.E. Sobel New insights into the metastasis-associated 67 kD laminin receptor J. Cell. Biochem. 67 1997 155 165 (Pubitemid 27431160)
    • (1997) Journal of Cellular Biochemistry , vol.67 , Issue.2 , pp. 155-165
    • Menard, S.1    Castronovo, V.2    Tagliabue, E.3    Sobel, M.E.4
  • 56
    • 41249088680 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate signaling pathway through 67-kDa laminin receptor
    • D. Umeda, S. Yano, K. Yamada, and H. Tachibana Green tea polyphenol epigallocatechin-3-gallate signaling pathway through 67-kDa laminin receptor J. Biol. Chem. 283 2008 3050 3058
    • (2008) J. Biol. Chem. , vol.283 , pp. 3050-3058
    • Umeda, D.1    Yano, S.2    Yamada, K.3    Tachibana, H.4
  • 57
    • 77956202733 scopus 로고    scopus 로고
    • Vitamin A enhances antitumor effect of a green tea polyphenol on melanoma by upregulating the polyphenol sensing molecule 67-kDa laminin receptor
    • J.H. Lee, M. Kishikawa, M. Kumazoe, K. Yamada, and H. Tachibana Vitamin A enhances antitumor effect of a green tea polyphenol on melanoma by upregulating the polyphenol sensing molecule 67-kDa laminin receptor PLoS ONE 5 2010 e11051
    • (2010) PLoS ONE , vol.5 , pp. 11051
    • Lee, J.H.1    Kishikawa, M.2    Kumazoe, M.3    Yamada, K.4    Tachibana, H.5
  • 59
    • 70349266564 scopus 로고    scopus 로고
    • Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect
    • Y. Chen, R. Cairns, I. Papandreou, A. Koong, and N.C. Denko Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect PLoS ONE 4 2009 e7033
    • (2009) PLoS ONE , vol.4 , pp. 7033
    • Chen, Y.1    Cairns, R.2    Papandreou, I.3    Koong, A.4    Denko, N.C.5
  • 61
    • 33745303045 scopus 로고    scopus 로고
    • Hypoxia signalling in cancer and approaches to enforce tumour regression
    • DOI 10.1038/nature04871, PII NATURE04871
    • J. Pouyssegur, F. Dayan, and N.M. Mazure Hypoxia signalling in cancer and approaches to enforce tumour regression Nature 441 2006 437 443 (Pubitemid 44050138)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 437-443
    • Pouyssegur, J.1    Dayan, F.2    Mazure, N.M.3
  • 62
    • 35148828429 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 (HIF-1) pathway
    • G.L. Semenza Hypoxia-inducible factor 1 (HIF-1) pathway Sci STKE 2007 2007 cm8.
    • (2007) Sci STKE 2007
    • Semenza, G.L.1
  • 63
    • 76049100577 scopus 로고    scopus 로고
    • HIF-1: Upstream and downstream of cancer metabolism
    • G.L. Semenza HIF-1: upstream and downstream of cancer metabolism Curr. Opin. Genet. Dev. 20 2010 51 56
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , pp. 51-56
    • Semenza, G.L.1
  • 64
    • 34247614521 scopus 로고    scopus 로고
    • HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity
    • DOI 10.1016/j.ccr.2007.04.001, PII S1535610807001158
    • H. Zhang, P. Gao, R. Fukuda, G. Kumar, B. Krishnamachary, K.I. Zeller, C.V. Dang, and G.L. Semenza HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity Cancer Cell 11 2007 407 420 (Pubitemid 46670080)
    • (2007) Cancer Cell , vol.11 , Issue.5 , pp. 407-420
    • Zhang, H.1    Gao, P.2    Fukuda, R.3    Kumar, G.4    Krishnamachary, B.5    Zeller, K.I.6    Dang, ChiV.7    Semenza, G.L.8
  • 65
    • 33947724515 scopus 로고    scopus 로고
    • HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
    • DOI 10.1016/j.cell.2007.01.047, PII S0092867407003078
    • R. Fukuda, H. Zhang, J.W. Kim, L. Shimoda, C.V. Dang, and G.L. Semenza HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells Cell 129 2007 111 122 (Pubitemid 46507584)
    • (2007) Cell , vol.129 , Issue.1 , pp. 111-122
    • Fukuda, R.1    Zhang, H.2    Kim, J.-w.3    Shimoda, L.4    Dang, C.V.5    Semenza, GreggL.6
  • 66
    • 33744783432 scopus 로고    scopus 로고
    • Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
    • DOI 10.1016/j.ccr.2006.04.023, PII S1535610806001450
    • V.R. Fantin, J. St-Pierre, and P. Leder Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance Cancer Cell 9 2006 425 434 (Pubitemid 43832190)
    • (2006) Cancer Cell , vol.9 , Issue.6 , pp. 425-434
    • Fantin, V.R.1    St-Pierre, J.2    Leder, P.3
  • 68
    • 35448964610 scopus 로고    scopus 로고
    • Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the 'Warburg Effect', i.e., elevated glycolysis in the presence of oxygen
    • DOI 10.1007/s10863-007-9094-x, Special Topic: The Warburg Effect: Its Continued Impact on Cancer Research into the 21st Century
    • P.L. Pedersen Warburg, me and Hexokinase 2: multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen J. Bioenerg. Biomembr. 39 2007 211 222 (Pubitemid 47619382)
    • (2007) Journal of Bioenergetics and Biomembranes , vol.39 , Issue.3 , pp. 211-222
    • Pedersen, P.L.1
  • 69
    • 28544436922 scopus 로고    scopus 로고
    • Activation of glycogen synthase kinase 3β disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity
    • DOI 10.1158/0008-5472.CAN-05-1925
    • J.G. Pastorino, J.B. Hoek, and N. Shulga Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity Cancer Res. 65 2005 10545 10554 (Pubitemid 41743749)
    • (2005) Cancer Research , vol.65 , Issue.22 , pp. 10545-10554
    • Pastorino, J.G.1    Hoek, J.B.2    Shulga, N.3
  • 70
    • 39449114808 scopus 로고    scopus 로고
    • Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II
    • DOI 10.1038/sj.cdd.4402285, PII 4402285
    • S. Miyamoto, A.N. Murphy, and J.H. Brown Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II Cell Death Differ. 15 2008 521 529 (Pubitemid 351267303)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.3 , pp. 521-529
    • Miyamoto, S.1    Murphy, A.N.2    Brown, J.H.3
  • 71
    • 71549172179 scopus 로고    scopus 로고
    • PI-3-K and AKT: Onto the mitochondria
    • B.L. Stiles PI-3-K and AKT: onto the mitochondria Adv. Drug Deliv. Rev. 61 2009 1276 1282
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 1276-1282
    • Stiles, B.L.1
  • 72
    • 33746927077 scopus 로고    scopus 로고
    • Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt
    • DOI 10.1038/sj.onc.1209595, PII 1209595
    • R.B. Robey, and N. Hay Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt Oncogene 25 2006 4683 4696 (Pubitemid 44187618)
    • (2006) Oncogene , vol.25 , Issue.34 , pp. 4683-4696
    • Robey, R.B.1    Hay, N.2
  • 73
    • 77951233410 scopus 로고    scopus 로고
    • Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition
    • Y. Fan, K.G. Dickman, and W.X. Zong Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition J. Biol. Chem. 285 2009 7324 7333
    • (2009) J. Biol. Chem. , vol.285 , pp. 7324-7333
    • Fan, Y.1    Dickman, K.G.2    Zong, W.X.3
  • 74
    • 33845630758 scopus 로고    scopus 로고
    • Harnessing the hypoxia-inducible factor in cancer and ischemic disease
    • DOI 10.1016/j.bcp.2006.10.013, PII S0006295206006642
    • M.C. Brahimi-Horn, and J. Pouyssegur Harnessing the hypoxia-inducible factor in cancer and ischemic disease Biochem. Pharmacol. 73 2007 450 457 (Pubitemid 44958373)
    • (2007) Biochemical Pharmacology , vol.73 , Issue.3 , pp. 450-457
    • Brahimi-Horn, M.C.1    Pouyssegur, J.2
  • 75
    • 0033763820 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia
    • J.C. Chavez, F. Agani, P. Pichiule, and J.C. LaManna Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia J. Appl. Physiol. 89 2000 1937 1942
    • (2000) J. Appl. Physiol. , vol.89 , pp. 1937-1942
    • Chavez, J.C.1    Agani, F.2    Pichiule, P.3    Lamanna, J.C.4
  • 77
    • 33847023140 scopus 로고    scopus 로고
    • Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting
    • M.W. Dewhirst Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting Cancer Res. 67 2007 854 855
    • (2007) Cancer Res. , vol.67 , pp. 854-855
    • Dewhirst, M.W.1
  • 78
    • 67349241646 scopus 로고    scopus 로고
    • Gene regulation in response to graded hypoxia: The non-redundant roles of the oxygen sensors PHD and FIH in the HIF pathway
    • F. Dayan, M. Monticelli, J. Pouyssegur, and E. Pecou Gene regulation in response to graded hypoxia: the non-redundant roles of the oxygen sensors PHD and FIH in the HIF pathway J. Theor. Biol. 259 2009 304 316
    • (2009) J. Theor. Biol. , vol.259 , pp. 304-316
    • Dayan, F.1    Monticelli, M.2    Pouyssegur, J.3    Pecou, E.4
  • 79
    • 77949913600 scopus 로고    scopus 로고
    • Uncoupling protein-2 and cancer
    • G. Baffy Uncoupling protein-2 and cancer Mitochondrion 10 2010 243 252
    • (2010) Mitochondrion , vol.10 , pp. 243-252
    • Baffy, G.1
  • 80
    • 33749986033 scopus 로고    scopus 로고
    • Mitochondrial function and toxicity: Role of the B vitamin family on mitochondrial energy metabolism
    • DOI 10.1016/j.cbi.2006.04.014, PII S0009279706000998
    • F. Depeint, W.R. Bruce, N. Shangari, R. Mehta, and P.J. O'Brien Mitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolism Chem.-Biol. Interact. 163 2006 94 112 (Pubitemid 44572213)
    • (2006) Chemico-Biological Interactions , vol.163 , Issue.1-2 , pp. 94-112
    • Depeint, F.1    Bruce, W.R.2    Shangari, N.3    Mehta, R.4    O'Brien, P.J.5
  • 81
    • 33750001533 scopus 로고    scopus 로고
    • Mitochondrial function and toxicity: Role of B vitamins on the one-carbon transfer pathways
    • DOI 10.1016/j.cbi.2006.05.010, PII S0009279706001335
    • F. Depeint, W.R. Bruce, N. Shangari, R. Mehta, and P.J. O'Brien Mitochondrial function and toxicity: role of B vitamins on the one-carbon transfer pathways Chem.-Biol. Interact. 163 2006 113 132 (Pubitemid 44572216)
    • (2006) Chemico-Biological Interactions , vol.163 , Issue.1-2 , pp. 113-132
    • Depeint, F.1    Bruce, W.R.2    Shangari, N.3    Mehta, R.4    O'Brien, P.J.5
  • 82
    • 0030037140 scopus 로고    scopus 로고
    • Brain levels of thiamine and its phosphate esters in Friedreich's ataxia and spinocerebellar ataxia type 1
    • DOI 10.1002/mds.870110415
    • L. Bettendorff, F. Mastrogiacomo, J. LaMarche, S. Dozic, and S.J. Kish Brain levels of thiamine and its phosphate esters in Friedreich's ataxia and spinocerebellar ataxia type 1 Mov. Disord. 11 1996 437 439 (Pubitemid 26235784)
    • (1996) Movement Disorders , vol.11 , Issue.4 , pp. 437-439
    • Bettendorff, L.1    Mastrogiacomo, F.2    LaMarche, J.3    Dozic, S.4    Kish, S.J.5
  • 83
    • 0033832914 scopus 로고    scopus 로고
    • A novel mutation in the thiamine responsive megaloblastic anaemia gene SLC19A2 in a patient with deficiency of respiratory chain complex i
    • C. Scharfe, M. Hauschild, T. Klopstock, A.J. Janssen, P.H. Heidemann, T. Meitinger, and M. Jaksch A novel mutation in the thiamine responsive megaloblastic anaemia gene SLC19A2 in a patient with deficiency of respiratory chain complex I J. Med. Genet. 37 2000 669 673
    • (2000) J. Med. Genet. , vol.37 , pp. 669-673
    • Scharfe, C.1    Hauschild, M.2    Klopstock, T.3    Janssen, A.J.4    Heidemann, P.H.5    Meitinger, T.6    Jaksch, M.7
  • 84
    • 0345303978 scopus 로고    scopus 로고
    • Marginal dietary thiamin deficiency induces the formation of colonic aberrant crypt foci (ACF) in rats
    • DOI 10.1016/j.canlet.2003.08.005
    • W.R. Bruce, R. Furrer, N. Shangari, P.J. O'Brien, A. Medline, and Y. Wang Marginal dietary thiamin deficiency induces the formation of colonic aberrant crypt foci (ACF) in rats Cancer Lett. 202 2003 125 129 (Pubitemid 37485884)
    • (2003) Cancer Letters , vol.202 , Issue.2 , pp. 125-129
    • Bruce, W.R.1    Furrer, R.2    Shangari, N.3    O'Brien, P.J.4    Medline, A.5    Wang, Y.6
  • 85
    • 70249150389 scopus 로고    scopus 로고
    • Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: A cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation
    • V.I. Bunik, and A.R. Fernie Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation Biochem. J. 422 2009 405 421
    • (2009) Biochem. J. , vol.422 , pp. 405-421
    • Bunik, V.I.1    Fernie, A.R.2
  • 86
    • 59749096845 scopus 로고    scopus 로고
    • Prolyl hydroxylases as regulators of cell metabolism
    • H. Boulahbel, R.V. Duran, and E. Gottlieb Prolyl hydroxylases as regulators of cell metabolism Biochem. Soc. Trans. 37 2009 291 294
    • (2009) Biochem. Soc. Trans. , vol.37 , pp. 291-294
    • Boulahbel, H.1    Duran, R.V.2    Gottlieb, E.3
  • 87
    • 0025870665 scopus 로고
    • Glutathione and related indices in rat lenses, liver and red cells during riboflavin deficiency and its correction
    • C.J. Bates Glutathione and related indices in rat lenses, liver and red cells during riboflavin deficiency and its correction Exp. Eye Res. 53 1991 123 130
    • (1991) Exp. Eye Res. , vol.53 , pp. 123-130
    • Bates, C.J.1
  • 88
    • 0026783268 scopus 로고
    • FAD-dependent regulation of transcription, translation, post-translational processing, and post-processing stability of various mitochondrial acyl-CoA dehydrogenases and of electron transfer flavoprotein and the site of holoenzyme formation
    • M. Nagao, and K. Tanaka FAD-dependent regulation of transcription, translation, post-translational processing, and post-processing stability of various mitochondrial acyl-CoA dehydrogenases and of electron transfer flavoprotein and the site of holoenzyme formation J. Biol. Chem. 267 1992 17925 17932
    • (1992) J. Biol. Chem. , vol.267 , pp. 17925-17932
    • Nagao, M.1    Tanaka, K.2
  • 89
    • 3042613609 scopus 로고    scopus 로고
    • Heme, iron, and the mitochondrial decay of ageing
    • DOI 10.1016/j.arr.2004.02.002, PII S1568163704000121
    • H. Atamna Heme, iron, and the mitochondrial decay of ageing Ageing Res. Rev. 3 2004 303 318 (Pubitemid 38844697)
    • (2004) Ageing Research Reviews , vol.3 , Issue.3 , pp. 303-318
    • Atamna, H.1
  • 92
    • 77952564025 scopus 로고    scopus 로고
    • Poly ADP-ribose polymerase-1 and health
    • J.B. Kirkland Poly ADP-ribose polymerase-1 and health Exp. Biol. Med. (Maywood, N.J 235 2010 561 568
    • (2010) Exp. Biol. Med. (Maywood, N.J , vol.235 , pp. 561-568
    • Kirkland, J.B.1
  • 94
    • 67949102053 scopus 로고    scopus 로고
    • Recent progress in the biology and physiology of sirtuins
    • T. Finkel, C.X. Deng, and R. Mostoslavsky Recent progress in the biology and physiology of sirtuins Nature 460 2009 587 591
    • (2009) Nature , vol.460 , pp. 587-591
    • Finkel, T.1    Deng, C.X.2    Mostoslavsky, R.3
  • 95
    • 77949887506 scopus 로고    scopus 로고
    • Mammalian sirtuins: Biological insights and disease relevance
    • M.C. Haigis, and D.A. Sinclair Mammalian sirtuins: biological insights and disease relevance Annu. Rev. Pathol. 5 2010 253 295
    • (2010) Annu. Rev. Pathol. , vol.5 , pp. 253-295
    • Haigis, M.C.1    Sinclair, D.A.2
  • 96
    • 77953257025 scopus 로고    scopus 로고
    • Aging and disease: Connections to sirtuins
    • G. Donmez, and L. Guarente Aging and disease: connections to sirtuins Aging Cell 9 2010 285 290
    • (2010) Aging Cell , vol.9 , pp. 285-290
    • Donmez, G.1    Guarente, L.2
  • 97
    • 42049114034 scopus 로고    scopus 로고
    • Transcriptional paradigms in mammalian mitochondrial biogenesis and function
    • DOI 10.1152/physrev.00025.2007
    • R.C. Scarpulla Transcriptional paradigms in mammalian mitochondrial biogenesis and function Physiol. Rev. 88 2008 611 638 (Pubitemid 351520089)
    • (2008) Physiological Reviews , vol.88 , Issue.2 , pp. 611-638
    • Scarpulla, R.C.1
  • 103
    • 0032769935 scopus 로고    scopus 로고
    • Optimum nutrition: Thiamin, biotin and pantothenate
    • D.A. Bender Optimum nutrition: thiamin, biotin and pantothenate Proc. Nutr. Soc. 58 1999 427 433 (Pubitemid 29398129)
    • (1999) Proceedings of the Nutrition Society , vol.58 , Issue.2 , pp. 427-433
    • Bender, D.A.1
  • 104
    • 0142043994 scopus 로고    scopus 로고
    • Protection by pantothenic acid against apoptosis and cell damage by oxygen free radicals - The role of glutathione
    • L. Wojtczak, and V.S. Slyshenkov Protection by pantothenic acid against apoptosis and cell damage by oxygen free radicals-the role of glutathione Bio.Factors (Oxford, England) 17 2003 61 73 (Pubitemid 37267142)
    • (2003) BioFactors , vol.17 , Issue.1-4 , pp. 61-73
    • Wojtczak, L.1    Slyshenkov, V.S.2
  • 106
    • 60549087188 scopus 로고    scopus 로고
    • A novel, enigmatic histone modification: Biotinylation of histones by holocarboxylase synthetase
    • Y.I. Hassan, and J. Zempleni A novel, enigmatic histone modification: biotinylation of histones by holocarboxylase synthetase Nutr. Rev. 66 2008 721 725
    • (2008) Nutr. Rev. , vol.66 , pp. 721-725
    • Hassan, Y.I.1    Zempleni, J.2
  • 107
    • 33845999254 scopus 로고    scopus 로고
    • Biotin deficiency inhibits heme synthesis and impairs mitochondria in human lung fibroblasts
    • H. Atamna, J. Newberry, R. Erlitzki, C.S. Schultz, and B.N. Ames Biotin deficiency inhibits heme synthesis and impairs mitochondria in human lung fibroblasts J. Nutr. 137 2007 25 30 (Pubitemid 46052854)
    • (2007) Journal of Nutrition , vol.137 , Issue.1 , pp. 25-30
    • Atamna, H.1    Newberry, J.2    Erlitzki, R.3    Schultz, C.S.4    Ames, B.N.5
  • 108
    • 51849127760 scopus 로고    scopus 로고
    • Folate-mediated one-carbon metabolism
    • J.T. Fox, and P.J. Stover Folate-mediated one-carbon metabolism Vitam. Horm. 79 2008 1 44
    • (2008) Vitam. Horm. , vol.79 , pp. 1-44
    • Fox, J.T.1    Stover, P.J.2
  • 109
    • 68849116328 scopus 로고    scopus 로고
    • Cobalamin, folic acid, and homocysteine
    • G. Varela-Moreiras, M.M. Murphy, and J.M. Scott Cobalamin, folic acid, and homocysteine Nutr. Rev. 67 Suppl 1 2009 S69 72
    • (2009) Nutr. Rev. , vol.67 , Issue.SUPPL. 1 , pp. 69-72
    • Varela-Moreiras, G.1    Murphy, M.M.2    Scott, J.M.3
  • 110
    • 77952803052 scopus 로고    scopus 로고
    • Vitamin B12: Unique metalorganic compounds and the most complex vitamins
    • L. Randaccio, S. Geremia, N. Demitri, and J. Wuerges Vitamin B12: unique metalorganic compounds and the most complex vitamins Mol. (Basel, Switzerland) 15 2010 3228 3259
    • (2010) Mol. (Basel, Switzerland) , vol.15 , pp. 3228-3259
    • Randaccio, L.1    Geremia, S.2    Demitri, N.3    Wuerges, J.4
  • 111
    • 1542710344 scopus 로고    scopus 로고
    • Nuclear retinoid receptors and the transcription of retinoid-target genes
    • DOI 10.1016/j.gene.2003.12.005, PII S0378111903011296
    • J. Bastien, and C. Rochette-Egly Nuclear retinoid receptors and the transcription of retinoid-target genes Gene 328 2004 1 16 (Pubitemid 38352876)
    • (2004) Gene , vol.328 , Issue.1-2 , pp. 1-16
    • Bastien, J.1    Rochette-Egly, C.2
  • 115
    • 0032589204 scopus 로고    scopus 로고
    • Folate and vitamin B12
    • J.M. Scott Folate and vitamin B12 Proc. Nutr. Soc. 58 1999 441 448
    • (1999) Proc. Nutr. Soc. , vol.58 , pp. 441-448
    • Scott, J.M.1
  • 117
    • 48349135395 scopus 로고    scopus 로고
    • Modeling folate, one-carbon metabolism, and DNA methylation
    • C.M. Ulrich, M.C. Reed, and H.F. Nijhout Modeling folate, one-carbon metabolism, and DNA methylation Nutr. Rev. 66 Suppl 1 2008 S27 30
    • (2008) Nutr. Rev. , vol.66 , Issue.SUPPL. 1 , pp. 27-30
    • Ulrich, C.M.1    Reed, M.C.2    Nijhout, H.F.3
  • 118
    • 51849129860 scopus 로고    scopus 로고
    • Mathematical models of folate-mediated one-carbon metabolism
    • H.F. Nijhout, M.C. Reed, and C.M. Ulrich Mathematical models of folate-mediated one-carbon metabolism Vitam. Horm. 79 2008 45 82
    • (2008) Vitam. Horm. , vol.79 , pp. 45-82
    • Nijhout, H.F.1    Reed, M.C.2    Ulrich, C.M.3
  • 119
    • 72249114913 scopus 로고    scopus 로고
    • One-carbon metabolism-genome interactions in folate-associated pathologies
    • P.J. Stover One-carbon metabolism-genome interactions in folate-associated pathologies J. Nutr. 139 2009 2402 2405
    • (2009) J. Nutr. , vol.139 , pp. 2402-2405
    • Stover, P.J.1
  • 120
    • 0024560579 scopus 로고
    • 12-dependent methionine synthetase on the subcellular distribution of folate coenzymes in rat liver
    • DOI 10.1016/0003-9861(89)90556-0
    • D.W. Horne, D. Patterson, and R.J. Cook Effect of nitrous oxide inactivation of vitamin B12-dependent methionine synthetase on the subcellular distribution of folate coenzymes in rat liver Arch. Biochem. Biophys. 270 1989 729 733 (Pubitemid 19109044)
    • (1989) Archives of Biochemistry and Biophysics , vol.270 , Issue.2 , pp. 729-733
    • Horne, D.W.1    Patterson, D.2    Cook, R.J.3
  • 121
    • 0025954883 scopus 로고
    • Compartmentation of folate-mediated one-carbon metabolism in eukaryotes
    • D.R. Appling Compartmentation of folate-mediated one-carbon metabolism in eukaryotes FASEB J. 5 1991 2645 2651 (Pubitemid 21905815)
    • (1991) FASEB Journal , vol.5 , Issue.12 , pp. 2645-2651
    • Appling, D.R.1
  • 122
    • 0027501365 scopus 로고
    • Regulation of folate and one-carbon metabolism in mammalian cells. III. Role of mitochondrial folylpoly-γ-glutamate synthetase
    • B.F. Lin, R.F. Huang, and B. Shane Regulation of folate and one-carbon metabolism in mammalian cells. III. Role of mitochondrial folylpoly-gamma- glutamate synthetase J. Biol. Chem. 268 1993 21674 21679 (Pubitemid 23320662)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.29 , pp. 21674-21679
    • Lin, B.-F.1    Huang, R.-F.S.2    Shane, B.3
  • 123
    • 77955616558 scopus 로고    scopus 로고
    • Compartmentalization of Mammalian folate-mediated one-carbon metabolism
    • A.S. Tibbetts, and D.R. Appling Compartmentalization of Mammalian folate-mediated one-carbon metabolism Annu. Rev. Nutr. 30 2010 57 81
    • (2010) Annu. Rev. Nutr. , vol.30 , pp. 57-81
    • Tibbetts, A.S.1    Appling, D.R.2
  • 124
    • 33745095012 scopus 로고    scopus 로고
    • Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and mammals
    • DOI 10.1002/bies.20420
    • K.E. Christensen, and R.E. MacKenzie Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and mammals Bioessays 28 2006 595 605 (Pubitemid 43886185)
    • (2006) BioEssays , vol.28 , Issue.6 , pp. 595-605
    • Christensen, K.E.1    MacKenzie, R.E.2
  • 125
    • 0034118587 scopus 로고    scopus 로고
    • Chemopreventive effects of dietary folate on intestinal polyps in Apc+/- Msh2-/- Mice
    • J. Song, K.J. Sohn, A. Medline, C. Ash, S. Gallinger, and Y.I. Kim Chemopreventive effects of dietary folate on intestinal polyps in Apc+/-Msh2-/- mice Cancer Res. 60 2000 3191 3199 (Pubitemid 30407916)
    • (2000) Cancer Research , vol.60 , Issue.12 , pp. 3191-3199
    • Song, J.1    Sohn, K.-J.2    Medline, A.3    Ash, C.4    Gallinger, S.5    Kim, Y.-I.6
  • 126
    • 0034307291 scopus 로고    scopus 로고
    • Effects of dietary folate on intestinal tumorigenesis in the apcMin mouse
    • J. Song, A. Medline, J.B. Mason, S. Gallinger, and Y.I. Kim Effects of dietary folate on intestinal tumorigenesis in the apcMin mouse Cancer Res. 60 2000 5434 5440
    • (2000) Cancer Res. , vol.60 , pp. 5434-5440
    • Song, J.1    Medline, A.2    Mason, J.B.3    Gallinger, S.4    Kim, Y.I.5
  • 127
    • 70249095935 scopus 로고    scopus 로고
    • Effect of folic acid supplementation on the progression of colorectal aberrant crypt foci
    • G.M. Lindzon, A. Medline, K.J. Sohn, F. Depeint, R. Croxford, and Y.I. Kim Effect of folic acid supplementation on the progression of colorectal aberrant crypt foci Carcinogenesis 30 2009 1536 1543
    • (2009) Carcinogenesis , vol.30 , pp. 1536-1543
    • Lindzon, G.M.1    Medline, A.2    Sohn, K.J.3    Depeint, F.4    Croxford, R.5    Kim, Y.I.6
  • 130
    • 0024328822 scopus 로고
    • Aberrant mitochondria in two human colon carcinoma cell lines
    • J.S. Modica-Napolitano, G.D. Steele Jr., and L.B. Chen Aberrant mitochondria in two human colon carcinoma cell lines Cancer Res. 49 1989 3369 3373 (Pubitemid 19162152)
    • (1989) Cancer Research , vol.49 , Issue.12 , pp. 3369-3373
    • Modica-Napolitano, J.S.1    Steele Jr., G.D.2    Chen, L.B.3
  • 131
    • 13444306450 scopus 로고    scopus 로고
    • Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators
    • DOI 10.1128/MCB.25.4.1354-1366.2005
    • N. Gleyzer, K. Vercauteren, and R.C. Scarpulla Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators Mol. Cell. Biol. 25 2005 1354 1366 (Pubitemid 40204913)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.4 , pp. 1354-1366
    • Gleyzer, N.1    Vercauteren, K.2    Scarpulla, R.C.3
  • 132
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
    • DOI 10.1038/nature03354
    • J.T. Rodgers, C. Lerin, W. Haas, S.P. Gygi, B.M. Spiegelman, and P. Puigserver Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1 Nature 434 2005 113 118 (Pubitemid 40349395)
    • (2005) Nature , vol.434 , Issue.7029 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3    Gygi, S.P.4    Spiegelman, B.M.5    Puigserver, P.6
  • 133
    • 33645011201 scopus 로고    scopus 로고
    • Nuclear control of respiratory gene expression in mammalian cells
    • R.C. Scarpulla Nuclear control of respiratory gene expression in mammalian cells J. Cell. Biochem. 97 2006 673 683
    • (2006) J. Cell. Biochem. , vol.97 , pp. 673-683
    • Scarpulla, R.C.1
  • 135
    • 77449139468 scopus 로고    scopus 로고
    • PGC-1alpha activation as a therapeutic approach in mitochondrial disease
    • T. Wenz PGC-1alpha activation as a therapeutic approach in mitochondrial disease IUBMB Life 61 2009 1051 1062
    • (2009) IUBMB Life , vol.61 , pp. 1051-1062
    • Wenz, T.1
  • 138
    • 0035016566 scopus 로고    scopus 로고
    • PGC-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells
    • DOI 10.1128/MCB.21.11.3738-3749.2001
    • U. Andersson, and R.C. Scarpulla Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells Mol. Cell. Biol. 21 2001 3738 3749 (Pubitemid 32466987)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.11 , pp. 3738-3749
    • Andersson, U.1    Scarpulla, R.C.2
  • 139
    • 0037134493 scopus 로고    scopus 로고
    • The PGC-1-related protein PERC is a selective coactivator of estrogen receptor α
    • DOI 10.1074/jbc.M201134200
    • D. Kressler, S.N. Schreiber, D. Knutti, and A. Kralli The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha J. Biol. Chem. 277 2002 13918 13925 (Pubitemid 34967998)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.16 , pp. 13918-13925
    • Kressler, D.1    Schreiber, S.N.2    Knutti, D.3    Kralli, A.4
  • 140
    • 0037127204 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β), a novel PGC-1-related transcription coactivator associated with host cell factor
    • DOI 10.1074/jbc.C100631200
    • J. Lin, P. Puigserver, J. Donovan, P. Tarr, and B.M. Spiegelman Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta), a novel PGC-1-related transcription coactivator associated with host cell factor J. Biol. Chem. 277 2002 1645 1648 (Pubitemid 34968733)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.3 , pp. 1645-1648
    • Lin, J.1    Puigserver, P.2    Donovan, J.3    Tarr, P.4    Spiegelman, B.M.5
  • 142
    • 75149134754 scopus 로고    scopus 로고
    • Estrogen-related receptor alpha and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria
    • D. Mirebeau-Prunier, S. Le Pennec, C. Jacques, N. Gueguen, J. Poirier, Y. Malthiery, and F. Savagner Estrogen-related receptor alpha and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria FEBS J. 277 2010 713 725
    • (2010) FEBS J. , vol.277 , pp. 713-725
    • Mirebeau-Prunier, D.1    Le Pennec, S.2    Jacques, C.3    Gueguen, N.4    Poirier, J.5    Malthiery, Y.6    Savagner, F.7
  • 144
    • 37349110355 scopus 로고    scopus 로고
    • Metabolic adaptations through the PGC-1α and SIRT1 pathways
    • DOI 10.1016/j.febslet.2007.11.034, PII S0014579307011787
    • J.T. Rodgers, C. Lerin, Z. Gerhart-Hines, and P. Puigserver Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways FEBS Lett. 582 2008 46 53 (Pubitemid 350297246)
    • (2008) FEBS Letters , vol.582 , Issue.1 , pp. 46-53
    • Rodgers, J.T.1    Lerin, C.2    Gerhart-Hines, Z.3    Puigserver, P.4
  • 145
    • 77953292242 scopus 로고    scopus 로고
    • Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
    • J.E. Dominy Jr., Y. Lee, Z. Gerhart-Hines, and P. Puigserver Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5 Biochim. Biophys. Acta 1804 2010 1676 1683
    • (2010) Biochim. Biophys. Acta , vol.1804 , pp. 1676-1683
    • Dominy Jr., J.E.1    Lee, Y.2    Gerhart-Hines, Z.3    Puigserver, P.4
  • 149
    • 61849161135 scopus 로고    scopus 로고
    • Fatty acid facts, part II: Role in the prevention of carcinogenesis, or, more fish on the dish?
    • E.K. Pauwels, and K. Kairemo Fatty acid facts, part II: role in the prevention of carcinogenesis, or, more fish on the dish? Drug News Perspect. 21 2008 504 510
    • (2008) Drug News Perspect. , vol.21 , pp. 504-510
    • Pauwels, E.K.1    Kairemo, K.2
  • 150
    • 77952580135 scopus 로고    scopus 로고
    • Omega-3 fatty acids in cancer, the protectors of good and the killers of evil?
    • H. Gleissman, J.I. Johnsen, and P. Kogner Omega-3 fatty acids in cancer, the protectors of good and the killers of evil? Exp. Cell Res. 316 2010 1365 1373
    • (2010) Exp. Cell Res. , vol.316 , pp. 1365-1373
    • Gleissman, H.1    Johnsen, J.I.2    Kogner, P.3
  • 153
    • 77953904162 scopus 로고    scopus 로고
    • Fatty acids from fish: The anti-inflammatory potential of long-chain omega-3 fatty acids
    • R. Wall, R.P. Ross, G.F. Fitzgerald, and C. Stanton Fatty acids from fish: the anti-inflammatory potential of long-chain omega-3 fatty acids Nutr. Rev. 68 2010 280 289
    • (2010) Nutr. Rev. , vol.68 , pp. 280-289
    • Wall, R.1    Ross, R.P.2    Fitzgerald, G.F.3    Stanton, C.4
  • 154
    • 70350555610 scopus 로고    scopus 로고
    • Role of lipoxins and resolvins as anti-inflammatory and proresolving mediators in colon cancer
    • N.B. Janakiram, and C.V. Rao Role of lipoxins and resolvins as anti-inflammatory and proresolving mediators in colon cancer Curr. Mol. Med. 9 2009 565 579
    • (2009) Curr. Mol. Med. , vol.9 , pp. 565-579
    • Janakiram, N.B.1    Rao, C.V.2
  • 155
    • 78650695097 scopus 로고    scopus 로고
    • Old and new generation lipid mediators in acute inflammation and resolution
    • M.J. Stables, and D.W. Gilroy Old and new generation lipid mediators in acute inflammation and resolution Prog. Lipid Res. 2010 doi:10.1016/j.plipres. 2010.07.005
    • (2010) Prog. Lipid Res.
    • Stables, M.J.1    Gilroy, D.W.2
  • 156
    • 7444246090 scopus 로고    scopus 로고
    • β-adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling
    • DOI 10.1096/fj.03-1067fje
    • M.J. Watt, G.R. Steinberg, S. Chan, A. Garnham, B.E. Kemp, and M.A. Febbraio Beta-adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling FASEB J. 18 2004 1445 1446 (Pubitemid 39561609)
    • (2004) FASEB Journal , vol.18 , Issue.12 , pp. 1445-1446
    • Watt, M.J.1    Steinberg, G.R.2    Chan, S.3    Garnham, A.4    Kemp, B.E.5    Febbraio, M.A.6
  • 157
    • 67650914230 scopus 로고    scopus 로고
    • AMPK in health and disease
    • G.R. Steinberg, and B.E. Kemp AMPK in health and disease Physiol. Rev. 89 2009 1025 1078
    • (2009) Physiol. Rev. , vol.89 , pp. 1025-1078
    • Steinberg, G.R.1    Kemp, B.E.2
  • 159
    • 33846012164 scopus 로고    scopus 로고
    • Role of AMPKalpha2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle
    • S.B. Jorgensen, J.T. Treebak, B. Viollet, P. Schjerling, S. Vaulont, J.F. Wojtaszewski, and E.A. Richter Role of AMPKalpha2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle Am. J. Physiol. 292 2007 E331 339
    • (2007) Am. J. Physiol. , vol.292 , pp. 331-339
    • Jorgensen, S.B.1    Treebak, J.T.2    Viollet, B.3    Schjerling, P.4    Vaulont, S.5    Wojtaszewski, J.F.6    Richter, E.A.7
  • 160
    • 62749096589 scopus 로고    scopus 로고
    • Mammalian target of rapamycin complex 1: Signalling inputs, substrates and feedback mechanisms
    • E.A. Dunlop, and A.R. Tee Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms Cell. Signal. 21 2009 827 835
    • (2009) Cell. Signal. , vol.21 , pp. 827-835
    • Dunlop, E.A.1    Tee, A.R.2
  • 161
    • 77952007543 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR): Conducting the cellular signaling symphony
    • K.G. Foster, and D.C. Fingar Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony J. Biol. Chem. 285 2010 14071 14077
    • (2010) J. Biol. Chem. , vol.285 , pp. 14071-14077
    • Foster, K.G.1    Fingar, D.C.2
  • 162
    • 60549111398 scopus 로고    scopus 로고
    • Is Akt the "warburg kinase"?-Akt-energy metabolism interactions and oncogenesis
    • R.B. Robey, and N. Hay Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis Semin. Cancer Biol. 19 2009 25 31
    • (2009) Semin. Cancer Biol. , vol.19 , pp. 25-31
    • Robey, R.B.1    Hay, N.2
  • 164
    • 73349087844 scopus 로고    scopus 로고
    • LKB1 and mammalian target of rapamycin as predictive factors for the anticancer efficacy of metformin
    • R.M. Memmott, and P.A. Dennis LKB1 and mammalian target of rapamycin as predictive factors for the anticancer efficacy of metformin J. Clin. Oncol. 27 2009 e226 author reply e227.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 226
    • Memmott, R.M.1    Dennis, P.A.2
  • 167
    • 69349091599 scopus 로고    scopus 로고
    • PPARgamma stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss
    • G. Miglio, A.C. Rosa, L. Rattazzi, M. Collino, G. Lombardi, and R. Fantozzi PPARgamma stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss Neurochem. Int. 55 2009 496 504
    • (2009) Neurochem. Int. , vol.55 , pp. 496-504
    • Miglio, G.1    Rosa, A.C.2    Rattazzi, L.3    Collino, M.4    Lombardi, G.5    Fantozzi, R.6
  • 168
    • 65649091280 scopus 로고    scopus 로고
    • Thiazolidinediones as anti-cancer agents
    • C. Blanquicett, J. Roman, and C.M. Hart Thiazolidinediones as anti-cancer agents Cancer ther. 6 2008 25 34
    • (2008) Cancer Ther. , vol.6 , pp. 25-34
    • Blanquicett, C.1    Roman, J.2    Hart, C.M.3
  • 169
    • 77951242981 scopus 로고    scopus 로고
    • Energy restriction as an antitumor target of thiazolidinediones
    • S. Wei, S.K. Kulp, and C.S. Chen Energy restriction as an antitumor target of thiazolidinediones J. Biol. Chem. 285 2010 9780 9791
    • (2010) J. Biol. Chem. , vol.285 , pp. 9780-9791
    • Wei, S.1    Kulp, S.K.2    Chen, C.S.3
  • 172
    • 48449104125 scopus 로고    scopus 로고
    • A combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of type 2 diabetic Goto-Kakizaki rats
    • W. Shen, J. Hao, C. Tian, J. Ren, L. Yang, X. Li, C. Luo, C.W. Cotma, and J. Liu A combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of type 2 diabetic Goto-Kakizaki rats PLoS ONE 3 2008 e2328
    • (2008) PLoS ONE , vol.3 , pp. 2328
    • Shen, W.1    Hao, J.2    Tian, C.3    Ren, J.4    Yang, L.5    Li, X.6    Luo, C.7    Cotma, C.W.8    Liu, J.9
  • 173
    • 77952833239 scopus 로고    scopus 로고
    • Alpha-lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling in the skeletal muscle of aged mice
    • Y. Wang, X. Li, Y. Guo, L. Chan, and X. Guan Alpha-lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling in the skeletal muscle of aged mice Metab., Clin. Exp. 59 2010 967 976
    • (2010) Metab., Clin. Exp. , vol.59 , pp. 967-976
    • Wang, Y.1    Li, X.2    Guo, Y.3    Chan, L.4    Guan, X.5
  • 174
    • 48549085904 scopus 로고    scopus 로고
    • Alpha-lipoic acid: The potential for use in cancer therapy
    • L. Novotny, P. Rauko, and C. Cojocel Alpha-lipoic acid: the potential for use in cancer therapy Neoplasma 55 2008 81 86
    • (2008) Neoplasma , vol.55 , pp. 81-86
    • Novotny, L.1    Rauko, P.2    Cojocel, C.3
  • 175
    • 43549122067 scopus 로고    scopus 로고
    • Alpha-lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway
    • D.Y. Shi, H.L. Liu, J.S. Stern, P.Z. Yu, and S.L. Liu Alpha-lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway FEBS Lett. 582 2008 1667 1671
    • (2008) FEBS Lett. , vol.582 , pp. 1667-1671
    • Shi, D.Y.1    Liu, H.L.2    Stern, J.S.3    Yu, P.Z.4    Liu, S.L.5
  • 176
    • 67649646949 scopus 로고    scopus 로고
    • Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A
    • K.P. Shay, and T.M. Hagen Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A Biogerontology 10 2009 443 456
    • (2009) Biogerontology , vol.10 , pp. 443-456
    • Shay, K.P.1    Hagen, T.M.2
  • 177
    • 24344504437 scopus 로고    scopus 로고
    • Endogenous production of lipoic acid is essential for mouse development
    • DOI 10.1128/MCB.25.18.8387-8392.2005
    • X. Yi, and N. Maeda Endogenous production of lipoic acid is essential for mouse development Mol. Cell. Biol. 25 2005 8387 8392 (Pubitemid 41263026)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.18 , pp. 8387-8392
    • Yi, X.1    Maeda, N.2
  • 179
    • 66049087696 scopus 로고    scopus 로고
    • The coordination of nuclear and mitochondrial communication during aging and calorie restriction
    • L.W. Finley, and M.C. Haigis The coordination of nuclear and mitochondrial communication during aging and calorie restriction Ageing Res. Rev. 8 2009 173 188
    • (2009) Ageing Res. Rev. , vol.8 , pp. 173-188
    • Finley, L.W.1    Haigis, M.C.2
  • 180
    • 60549096247 scopus 로고    scopus 로고
    • Akt-dependent and -independent mechanisms of mTOR regulation in cancer
    • R.M. Memmott, and P.A. Dennis Akt-dependent and -independent mechanisms of mTOR regulation in cancer Cell. Signal. 21 2009 656 664
    • (2009) Cell. Signal. , vol.21 , pp. 656-664
    • Memmott, R.M.1    Dennis, P.A.2
  • 181
    • 6944256628 scopus 로고    scopus 로고
    • Effect of n-3 fatty acids on the antitumour effects of cytotoxic drugs
    • M.P. Wynter, S.T. Russell, and M.J. Tisdale Effect of n-3 fatty acids on the antitumour effects of cytotoxic drugs In vivo (Athens, Greece) 18 2004 543 547
    • (2004) In Vivo (Athens, Greece) , vol.18 , pp. 543-547
    • Wynter, M.P.1    Russell, S.T.2    Tisdale, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.