-
1
-
-
0034946344
-
Folate and chemoprevention of colorectal cancer: Is 5-methyltetrahydrofolate an active antiproliferative agent in folate-treated colon-cancer cells?
-
Akoglu B., Faust D., Milovic V., and Stein J. Folate and chemoprevention of colorectal cancer: Is 5-methyltetrahydrofolate an active antiproliferative agent in folate-treated colon-cancer cells?. Nutrition 17 (2001) 652-653
-
(2001)
Nutrition
, vol.17
, pp. 652-653
-
-
Akoglu, B.1
Faust, D.2
Milovic, V.3
Stein, J.4
-
2
-
-
38949096170
-
Propagation of fluctuations in biochemical systems, II: Nonlinear chains
-
Anderson D.F., and Mattingly J.C. Propagation of fluctuations in biochemical systems, II: Nonlinear chains. IET Syst. Biol. 1 (2008) 313-325
-
(2008)
IET Syst. Biol.
, vol.1
, pp. 313-325
-
-
Anderson, D.F.1
Mattingly, J.C.2
-
3
-
-
34547666909
-
Propagation of fluctuations in biochemical systems, I: Linear SSC networks
-
Anderson D.F., Mattingly J.C., Nijhout H.F., and Reed M.C. Propagation of fluctuations in biochemical systems, I: Linear SSC networks. Bull. Math. Biol. 69 (2007) 1791-1813
-
(2007)
Bull. Math. Biol.
, vol.69
, pp. 1791-1813
-
-
Anderson, D.F.1
Mattingly, J.C.2
Nijhout, H.F.3
Reed, M.C.4
-
4
-
-
0025954883
-
Compartmentation of folate-mediated one-carbon metabolism in eukaryotes
-
Appling D. Compartmentation of folate-mediated one-carbon metabolism in eukaryotes. FASEB J 5 (1991) 2645-2651
-
(1991)
FASEB J
, vol.5
, pp. 2645-2651
-
-
Appling, D.1
-
5
-
-
0033762343
-
Synthesis of glutathione in response to methionine load in control subjects and in patients with cirrhosis
-
Bianchi G., Brizi M., Rossi B., Ronchi M., Grossi G., and Marchesini G. Synthesis of glutathione in response to methionine load in control subjects and in patients with cirrhosis. Metabolism 49 (2000) 1434-1439
-
(2000)
Metabolism
, vol.49
, pp. 1434-1439
-
-
Bianchi, G.1
Brizi, M.2
Rossi, B.3
Ronchi, M.4
Grossi, G.5
Marchesini, G.6
-
6
-
-
0035004799
-
Circadian expression of clock genes in human oral mucosa and skin association with specific cell-cycle phases
-
Bjarnason G.A., Jordan R.C., Wood P.A., Li Q., Lincoln D.W., Sothern R.B., Hrushesky W.J.M., and Ben-David Y. Circadian expression of clock genes in human oral mucosa and skin association with specific cell-cycle phases. Am. J. Pathol. 158 (2001) 1793-1801
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 1793-1801
-
-
Bjarnason, G.A.1
Jordan, R.C.2
Wood, P.A.3
Li, Q.4
Lincoln, D.W.5
Sothern, R.B.6
Hrushesky, W.J.M.7
Ben-David, Y.8
-
7
-
-
33745095012
-
Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and animals
-
Christensen K.E., and MacKenzie R.E. Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and animals. Bioessays 28 (2005) 595-605
-
(2005)
Bioessays
, vol.28
, pp. 595-605
-
-
Christensen, K.E.1
MacKenzie, R.E.2
-
8
-
-
0002705479
-
S-Adenosylmethionine-dependent methyltransferases
-
Carmel R., and Jacobsen D.W. (Eds), Cambridge Univ. Press, Cambridge
-
Clarke S., and Banfield K. S-Adenosylmethionine-dependent methyltransferases. In: Carmel R., and Jacobsen D.W. (Eds). Homocysteine in Health and Disease (2001), Cambridge Univ. Press, Cambridge 63-78
-
(2001)
Homocysteine in Health and Disease
, pp. 63-78
-
-
Clarke, S.1
Banfield, K.2
-
9
-
-
0001467691
-
Folate metabolism
-
Carmel R., and Jacobsen D.W. (Eds), Cambridge University Press, Cambridge
-
Cook R.J. Folate metabolism. In: Carmel R., and Jacobsen D.W. (Eds). Homocysteine in Health and Disease (2001), Cambridge University Press, Cambridge 113-134
-
(2001)
Homocysteine in Health and Disease
, pp. 113-134
-
-
Cook, R.J.1
-
10
-
-
17544393875
-
Regulation of mammalian liver methionine adenosyltransferase
-
Corrales F.J., Perez-Mato I., Sanchez del Pino M.M., Ruiz F., Castro C., Garcia-Trevijano E.R., Latasa U., Martinez-Chantar M.L., Martinez-Cruz A., Avila M.A., and Mato J.M. Regulation of mammalian liver methionine adenosyltransferase. J. Nutr. 132 (2002) 2377S-2381S
-
(2002)
J. Nutr.
, vol.132
-
-
Corrales, F.J.1
Perez-Mato, I.2
Sanchez del Pino, M.M.3
Ruiz, F.4
Castro, C.5
Garcia-Trevijano, E.R.6
Latasa, U.7
Martinez-Chantar, M.L.8
Martinez-Cruz, A.9
Avila, M.A.10
Mato, J.M.11
-
11
-
-
1242336874
-
MTHFR C677T and A1298C polymorphisms: Diet, estrogen, and risk of colon cancer
-
Curtin K., Bigler J., Slattery M.L., Caan B., Potter J.D., and Ulrich C.M. MTHFR C677T and A1298C polymorphisms: Diet, estrogen, and risk of colon cancer. Cancer Epidemiol. Biomarkers. Prev. 13 (2004) 285-292
-
(2004)
Cancer Epidemiol. Biomarkers. Prev.
, vol.13
, pp. 285-292
-
-
Curtin, K.1
Bigler, J.2
Slattery, M.L.3
Caan, B.4
Potter, J.D.5
Ulrich, C.M.6
-
12
-
-
4544329325
-
The primary prevention of birth defects: Multivitamins or folic acid?
-
Czeizel A.E. The primary prevention of birth defects: Multivitamins or folic acid?. Int. J. Med. Sci. 1 (2004) 50-61
-
(2004)
Int. J. Med. Sci.
, vol.1
, pp. 50-61
-
-
Czeizel, A.E.1
-
13
-
-
4444261606
-
The expression of mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase supports a role in rapid cell growth
-
Di Pietro E., Wang X.L., and MacKenzie R.E. The expression of mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase supports a role in rapid cell growth. Biochim. Biophys. Acta 1674 (2004) 78-84
-
(2004)
Biochim. Biophys. Acta
, vol.1674
, pp. 78-84
-
-
Di Pietro, E.1
Wang, X.L.2
MacKenzie, R.E.3
-
16
-
-
0026802334
-
Metabolic control analysis: A survey of its theoretical and experimental background
-
Fell D.A. Metabolic control analysis: A survey of its theoretical and experimental background. Biochem. J. 286 (1992) 313-330
-
(1992)
Biochem. J.
, vol.286
, pp. 313-330
-
-
Fell, D.A.1
-
17
-
-
0025362827
-
Methionine metabolism in mammals
-
Finkelstein J. Methionine metabolism in mammals. J. Nutr. Biochem. 1 (1990) 228-237
-
(1990)
J. Nutr. Biochem.
, vol.1
, pp. 228-237
-
-
Finkelstein, J.1
-
18
-
-
0002528229
-
Regulation of homocysteine metabolism
-
Carmel R., and Jacobsen D.W. (Eds), Cambridge Univ. Press, Cambridge
-
Finkelstein J. Regulation of homocysteine metabolism. In: Carmel R., and Jacobsen D.W. (Eds). Homocysteine in Health and Disease (2001), Cambridge Univ. Press, Cambridge 92-99
-
(2001)
Homocysteine in Health and Disease
, pp. 92-99
-
-
Finkelstein, J.1
-
19
-
-
0037797303
-
Methionine metabolism in liver disease
-
Finkelstein J. Methionine metabolism in liver disease. Am. J. Clin. Nutr. 77 (2003) 1094-1095
-
(2003)
Am. J. Clin. Nutr.
, vol.77
, pp. 1094-1095
-
-
Finkelstein, J.1
-
20
-
-
0021220516
-
Methionine metabolism in mammals: Distribution of homocysteine between competing pathways
-
Finkelstein J., and Martin J. Methionine metabolism in mammals: Distribution of homocysteine between competing pathways. J. Biol. Chem. 259 (1984) 9508-9513
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 9508-9513
-
-
Finkelstein, J.1
Martin, J.2
-
21
-
-
0023032002
-
Methionine metabolism in mammals: Adaptation to methionine excess
-
Finkelstein J., and Martin J. Methionine metabolism in mammals: Adaptation to methionine excess. J. Biol. Chem. 261 (1986) 1582-1587
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 1582-1587
-
-
Finkelstein, J.1
Martin, J.2
-
22
-
-
0015427721
-
Methionine metabolism in mammals: Kinetic study of betaine:Homocysteine methyltransferase
-
Finkelstein J.D., Harris B.J., and Kyle W.E. Methionine metabolism in mammals: Kinetic study of betaine:Homocysteine methyltransferase. Arch. Biochem. Biophys. 153 (1972) 320-324
-
(1972)
Arch. Biochem. Biophys.
, vol.153
, pp. 320-324
-
-
Finkelstein, J.D.1
Harris, B.J.2
Kyle, W.E.3
-
23
-
-
0016371704
-
Methionine metabolism in mammals: Regulatory effects of S-adenosylmethionine
-
Finkelstein J.D., Kyle W.E., and Harris B.J. Methionine metabolism in mammals: Regulatory effects of S-adenosylmethionine. Arch. Biochem. Biophys. 165 (1974) 774-779
-
(1974)
Arch. Biochem. Biophys.
, vol.165
, pp. 774-779
-
-
Finkelstein, J.D.1
Kyle, W.E.2
Harris, B.J.3
-
24
-
-
0020328164
-
Methionine metabolism in mammals: Concentrations of metabolites in rat tissues. Kinetic study of betaine:homocysteine methyltransferase
-
Finkelstein J.D., Harris B.J., and Martin J.J. Methionine metabolism in mammals: Concentrations of metabolites in rat tissues. Kinetic study of betaine:homocysteine methyltransferase. J. Nutr. 112 (1982) 1011-1018
-
(1982)
J. Nutr.
, vol.112
, pp. 1011-1018
-
-
Finkelstein, J.D.1
Harris, B.J.2
Martin, J.J.3
-
25
-
-
0029049553
-
A candidate genetic risk factor for vascular disease-A common mutation in methylenetetrahydrofolate reductase
-
Frosst P., Blom H.J., Milos R., Goyette P., Sheppard C.A., Matthews R.G., Boers G.J.H., Den Heijer M., Kluijtmans L.A.J., Van den Heuvel L.P., and Rozen R. A candidate genetic risk factor for vascular disease-A common mutation in methylenetetrahydrofolate reductase. Nat. Genet. 10 (1995) 111-113
-
(1995)
Nat. Genet.
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
Goyette, P.4
Sheppard, C.A.5
Matthews, R.G.6
Boers, G.J.H.7
Den Heijer, M.8
Kluijtmans, L.A.J.9
Van den Heuvel, L.P.10
Rozen, R.11
-
26
-
-
4944261919
-
Population study of expression of thymidylate synthase and dihydropyrimidine dehydrogenase in patients with solid tumors
-
Fukushima M., Morita M., Ikeda K., and Nagayama S. Population study of expression of thymidylate synthase and dihydropyrimidine dehydrogenase in patients with solid tumors. Int. J. Mol. Med. 12 (2003) 839-844
-
(2003)
Int. J. Mol. Med.
, vol.12
, pp. 839-844
-
-
Fukushima, M.1
Morita, M.2
Ikeda, K.3
Nagayama, S.4
-
27
-
-
0036399750
-
In vivo kinetics of folate metabolism
-
Gregory J.F., and Quinlivan E.P. In vivo kinetics of folate metabolism. Annu. Rev. Nutr. 22 (2002) 199-220
-
(2002)
Annu. Rev. Nutr.
, vol.22
, pp. 199-220
-
-
Gregory, J.F.1
Quinlivan, E.P.2
-
28
-
-
0031794154
-
2] folic acid: Isotopic labeling of urinary folate and the catabolite para-acetamidobenzoylglutamate indicates slow, intake-dependent, turnover of folate pools
-
2] folic acid: Isotopic labeling of urinary folate and the catabolite para-acetamidobenzoylglutamate indicates slow, intake-dependent, turnover of folate pools. J. Nutr. 128 (1998) 1896-1906
-
(1998)
J. Nutr.
, vol.128
, pp. 1896-1906
-
-
Gregory, J.F.1
Williamson, J.2
Liao, J.-F.3
Bailey, L.B.4
Toth, J.P.5
-
29
-
-
0022410121
-
Limits of adaptation: The evolution of selective neutrality
-
Hartl D.L., Dijkhuizen D.E., and Dean A.M. Limits of adaptation: The evolution of selective neutrality. Genetics 111 (1985) 655-674
-
(1985)
Genetics
, vol.111
, pp. 655-674
-
-
Hartl, D.L.1
Dijkhuizen, D.E.2
Dean, A.M.3
-
30
-
-
0016638077
-
Regulation in the folate pathway of Escherichia coli
-
Harvey R.J., and Dev I.K. Regulation in the folate pathway of Escherichia coli. Adv. Enzyme. Regul. 13 (1975) 99-124
-
(1975)
Adv. Enzyme. Regul.
, vol.13
, pp. 99-124
-
-
Harvey, R.J.1
Dev, I.K.2
-
31
-
-
0037064008
-
Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosynthesis
-
Herbig K., Chiang E.-P., Lee L.-R., Hills J., Shane B., and Stover P.J. Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosynthesis. J. Biol. Chem. 277 (2002) 38381-38389
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38381-38389
-
-
Herbig, K.1
Chiang, E.-P.2
Lee, L.-R.3
Hills, J.4
Shane, B.5
Stover, P.J.6
-
32
-
-
35348983887
-
A second generation human haplotype map of over 3.1 million SNPs
-
International HapMap Consortium
-
International HapMap Consortium. A second generation human haplotype map of over 3.1 million SNPs. Nature 449 (2007) 851-862
-
(2007)
Nature
, vol.449
, pp. 851-862
-
-
-
33
-
-
0018837126
-
Kinetic simulation of anticancer drug interactions
-
Jackson R.C. Kinetic simulation of anticancer drug interactions. Int. J. Biomed. Comput. 11 (1980) 197-224
-
(1980)
Int. J. Biomed. Comput.
, vol.11
, pp. 197-224
-
-
Jackson, R.C.1
-
34
-
-
0021281190
-
A kinetic model of regulation of the deoxyribonucleoside triphosphate pool composition
-
Jackson R.C. A kinetic model of regulation of the deoxyribonucleoside triphosphate pool composition. Pharmacol. Ther. 24 (1984) 279-301
-
(1984)
Pharmacol. Ther.
, vol.24
, pp. 279-301
-
-
Jackson, R.C.1
-
35
-
-
0022881437
-
Kinetic simulation of anticancer drug effects on metabolic pathway fluxes-Two case studies
-
Jackson R.C. Kinetic simulation of anticancer drug effects on metabolic pathway fluxes-Two case studies. Bull. Math. Biol. 48 (1986) 337-351
-
(1986)
Bull. Math. Biol.
, vol.48
, pp. 337-351
-
-
Jackson, R.C.1
-
36
-
-
0027538426
-
The kinetic properties of switch antimetabolites
-
Jackson R.C. The kinetic properties of switch antimetabolites. J. Nat. Cancer Inst. 85 (1993) 539-545
-
(1993)
J. Nat. Cancer Inst.
, vol.85
, pp. 539-545
-
-
Jackson, R.C.1
-
37
-
-
0029135393
-
Toxicity prediction from metabolic pathway modeling
-
Jackson R.C. Toxicity prediction from metabolic pathway modeling. Toxicology 102 (1995) 197-205
-
(1995)
Toxicology
, vol.102
, pp. 197-205
-
-
Jackson, R.C.1
-
38
-
-
0015817366
-
Studies with a mathematical model of folate metabolism
-
Jackson R.C., and Harrap K.R. Studies with a mathematical model of folate metabolism. Arch. Biochem. Biophys. 158 (1973) 827-841
-
(1973)
Arch. Biochem. Biophys.
, vol.158
, pp. 827-841
-
-
Jackson, R.C.1
Harrap, K.R.2
-
39
-
-
0018775814
-
Computer models of anti-cancer drug interaction
-
Jackson R.C., and Harrap K.R. Computer models of anti-cancer drug interaction. Pharmacol. Ther. 4 (1979) 245-280
-
(1979)
Pharmacol. Ther.
, vol.4
, pp. 245-280
-
-
Jackson, R.C.1
Harrap, K.R.2
-
40
-
-
0035807013
-
Regulation of human cystathionine beta-synthase by S-adenosyl-L-methionine: Evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region
-
Janosik M., Kery V., Gaustadnes M., Maclean K.N., and Kraus J.P. Regulation of human cystathionine beta-synthase by S-adenosyl-L-methionine: Evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region. Biochemistry 40 (2001) 10625-10633
-
(2001)
Biochemistry
, vol.40
, pp. 10625-10633
-
-
Janosik, M.1
Kery, V.2
Gaustadnes, M.3
Maclean, K.N.4
Kraus, J.P.5
-
41
-
-
0023664009
-
Allosteric inhibition of methylenetetrahydrofolate reductase by adenosylmethionine. Effects of adenosylmethionine and NADPH on the equilibrium between active and inactive forms of the enzyme and on the kinetics of approach to equilibrium
-
Jencks D.A., and Matthews R.G. Allosteric inhibition of methylenetetrahydrofolate reductase by adenosylmethionine. Effects of adenosylmethionine and NADPH on the equilibrium between active and inactive forms of the enzyme and on the kinetics of approach to equilibrium. J. Biol. Chem. 262 (1987) 2485-2493
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 2485-2493
-
-
Jencks, D.A.1
Matthews, R.G.2
-
42
-
-
0030862155
-
Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in Saccharomyces cerevisiae
-
Kastanos E.K., Woldman Y.Y., and Appling D.R. Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in Saccharomyces cerevisiae. Biochemistry 36 (1997) 14956-14964
-
(1997)
Biochemistry
, vol.36
, pp. 14956-14964
-
-
Kastanos, E.K.1
Woldman, Y.Y.2
Appling, D.R.3
-
43
-
-
0030057995
-
Defective cystathionine beta-synthase regulation by S-adenosylmethionine in a partially pyridoxine responsive homocystinuria patient
-
Kluijtmans L.A.J., Boers G.H.J., Stevens E.M.B., Renier W.O., Kraus J.P., Trijbels F.J.M., Van den Heuvel L.P.W.J., and Blom H.J. Defective cystathionine beta-synthase regulation by S-adenosylmethionine in a partially pyridoxine responsive homocystinuria patient. J. Clin. Invest. 98 (1996) 285-289
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 285-289
-
-
Kluijtmans, L.A.J.1
Boers, G.H.J.2
Stevens, E.M.B.3
Renier, W.O.4
Kraus, J.P.5
Trijbels, F.J.M.6
Van den Heuvel, L.P.W.J.7
Blom, H.J.8
-
44
-
-
36749011792
-
Flavin-dependent thymidylate synthase ThyX activity: Implications for the folate cycle in bacteria
-
Leduc D., Escartin F., Nijhout H.F., Reed M.C., Liebl U., Skouloubris S., and Myllykallio H. Flavin-dependent thymidylate synthase ThyX activity: Implications for the folate cycle in bacteria. J. Bacteriol. 189 (2007) 8537-8545
-
(2007)
J. Bacteriol.
, vol.189
, pp. 8537-8545
-
-
Leduc, D.1
Escartin, F.2
Nijhout, H.F.3
Reed, M.C.4
Liebl, U.5
Skouloubris, S.6
Myllykallio, H.7
-
45
-
-
33845778866
-
Cytoplasmic serine hydroxymethyltransferase regulates the homocysteine remethylation pathway
-
MacFarlane A.J., Perry C., Liu X., Allen S., and Stover P.J. Cytoplasmic serine hydroxymethyltransferase regulates the homocysteine remethylation pathway. Haematol. Rep. 1 (2005) 28
-
(2005)
Haematol. Rep.
, vol.1
, pp. 28
-
-
MacFarlane, A.J.1
Perry, C.2
Liu, X.3
Allen, S.4
Stover, P.J.5
-
46
-
-
0034697625
-
A substrate switch: A new mode of regulation in the methionine metabolic pathway
-
Martinov M., Vitvitsky V., Mosharov E., Banerjee R., and Ataullakhanov F. A substrate switch: A new mode of regulation in the methionine metabolic pathway. J. Theor. Biol. 204 (2000) 521-532
-
(2000)
J. Theor. Biol.
, vol.204
, pp. 521-532
-
-
Martinov, M.1
Vitvitsky, V.2
Mosharov, E.3
Banerjee, R.4
Ataullakhanov, F.5
-
47
-
-
32944481700
-
Perspectives on human genetic variation from the HapMap project
-
McVean G., Spencer C.C.A., and Chaix R. Perspectives on human genetic variation from the HapMap project. PLOS Genet 1 (2005) e54
-
(2005)
PLOS Genet
, vol.1
-
-
McVean, G.1
Spencer, C.C.A.2
Chaix, R.3
-
48
-
-
0023695662
-
NAD-dependent methylenetetrahydrofolate dehydrogenase-methylenetatrahydrofolate cyclohydrolase in transformed cells is a mitochondrial enzyme
-
Mejia N.R., and MacKenzie R.E. NAD-dependent methylenetetrahydrofolate dehydrogenase-methylenetatrahydrofolate cyclohydrolase in transformed cells is a mitochondrial enzyme. Biochem. Biophys. Res. Commun 155 (1986) 1-6
-
(1986)
Biochem. Biophys. Res. Commun
, vol.155
, pp. 1-6
-
-
Mejia, N.R.1
MacKenzie, R.E.2
-
49
-
-
16844370424
-
Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons
-
Morris M.C., Evans D.A., Bienias J.L., Tangney C.C., Herbert L.E., Scherr P.A., and Schneider J.A. Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons. Arch. Neurol 62 (2005) 641-645
-
(2005)
Arch. Neurol
, vol.62
, pp. 641-645
-
-
Morris, M.C.1
Evans, D.A.2
Bienias, J.L.3
Tangney, C.C.4
Herbert, L.E.5
Scherr, P.A.6
Schneider, J.A.7
-
50
-
-
0024346102
-
Folate cycle kinetics in human breast cancer cells
-
Morrison P.F., and Allegra C.J. Folate cycle kinetics in human breast cancer cells. J. Biol. Chem. 264 (1989) 10552-10566
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 10552-10566
-
-
Morrison, P.F.1
Allegra, C.J.2
-
53
-
-
33744761589
-
Long-range allosteric interactions between the folate and methionine cycles stabilize DNA methylation reaction rate
-
Nijhout H.F., Reed M.C., Anderson D.F., Mattingly J.C., James S.J., and Ulrich C.M. Long-range allosteric interactions between the folate and methionine cycles stabilize DNA methylation reaction rate. Epigenetics 1 (2006) 81-87
-
(2006)
Epigenetics
, vol.1
, pp. 81-87
-
-
Nijhout, H.F.1
Reed, M.C.2
Anderson, D.F.3
Mattingly, J.C.4
James, S.J.5
Ulrich, C.M.6
-
54
-
-
33845727585
-
In silico experimentation with a model of hepatic mitochondrial folate metabolism
-
Nijhout H.F., Reed M.C., Lam S.-L., Shane B., Gregory J.F., and Ulrich C.M. In silico experimentation with a model of hepatic mitochondrial folate metabolism. Theor. Biol. Med. Model 3 (2007) 40ff
-
(2007)
Theor. Biol. Med. Model
, vol.3
-
-
Nijhout, H.F.1
Reed, M.C.2
Lam, S.-L.3
Shane, B.4
Gregory, J.F.5
Ulrich, C.M.6
-
56
-
-
0036677062
-
Role of retinoblastoma protein and E2F-1 transcription factor in the acquisition of 5-fluorouracil resistance by colon cancer cells
-
Obama K., Kanai M., Kawai Y., Fukushima M., and Takabayashi A. Role of retinoblastoma protein and E2F-1 transcription factor in the acquisition of 5-fluorouracil resistance by colon cancer cells. Int. J. Oncol. 21 (2002) 309-314
-
(2002)
Int. J. Oncol.
, vol.21
, pp. 309-314
-
-
Obama, K.1
Kanai, M.2
Kawai, Y.3
Fukushima, M.4
Takabayashi, A.5
-
57
-
-
33846333917
-
Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine
-
Ou X., Yang H., Ramani K., Ara A.I., Chen H., Mato J.M., and Lu S.C. Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine. Biochem. J. 401 (2007) 87-96
-
(2007)
Biochem. J.
, vol.401
, pp. 87-96
-
-
Ou, X.1
Yang, H.2
Ramani, K.3
Ara, A.I.4
Chen, H.5
Mato, J.M.6
Lu, S.C.7
-
58
-
-
0024422803
-
Nucleotide sequence of the human NAD-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase
-
Peri K.G., Belanger C., and MacKenzie R.E. Nucleotide sequence of the human NAD-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase. Nucleic Acids Res. 17 (1989) 8853
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 8853
-
-
Peri, K.G.1
Belanger, C.2
MacKenzie, R.E.3
-
59
-
-
0034969415
-
Homocysteine metabolism in children with down syndrome: In vitro modulation
-
Pogribna M., Melnyk S., Pogrybny I., Chango A., Yi P., and James J. Homocysteine metabolism in children with down syndrome: In vitro modulation. Am. J. Hum. Genet. 69 (2001) 88-95
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 88-95
-
-
Pogribna, M.1
Melnyk, S.2
Pogrybny, I.3
Chango, A.4
Yi, P.5
James, J.6
-
60
-
-
25144484893
-
Analysis of pathological defects in methionine metabolism using a simple mathematical model
-
Prudova A., Martinov M.V., Vitvitsky V.M., Ataullakhanov F.I., and Banerjee R. Analysis of pathological defects in methionine metabolism using a simple mathematical model. Biochim. Biophys. Acta 1741 (2005) 331-338
-
(2005)
Biochim. Biophys. Acta
, vol.1741
, pp. 331-338
-
-
Prudova, A.1
Martinov, M.V.2
Vitvitsky, V.M.3
Ataullakhanov, F.I.4
Banerjee, R.5
-
62
-
-
33749494516
-
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism
-
Reed M.C., Nijhout H.F., Neuhouser M.L., Gregory J.F., Shane B., James S.J., Boynton A., and Ulrich C.M. A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism. J. Nutr. 136 (2006) 2653-2661
-
(2006)
J. Nutr.
, vol.136
, pp. 2653-2661
-
-
Reed, M.C.1
Nijhout, H.F.2
Neuhouser, M.L.3
Gregory, J.F.4
Shane, B.5
James, S.J.6
Boynton, A.7
Ulrich, C.M.8
-
63
-
-
44349165122
-
A mathematical model of glutathione metabolism
-
(in press)
-
Reed M.C., Thomas R.L., Pavisic J., James S.J., Ulrich C.M., and Nijhout H.F. A mathematical model of glutathione metabolism. Theoret. Biol. Math. Model (2008) (in press)
-
(2008)
Theoret. Biol. Math. Model
-
-
Reed, M.C.1
Thomas, R.L.2
Pavisic, J.3
James, S.J.4
Ulrich, C.M.5
Nijhout, H.F.6
-
64
-
-
0036855185
-
Abundant raw material for cis-regulatory evolution in humans
-
Rockman M.V., and Wray G.A. Abundant raw material for cis-regulatory evolution in humans. Mol. Biol. Evol. 19 (2002) 1991-2004
-
(2002)
Mol. Biol. Evol.
, vol.19
, pp. 1991-2004
-
-
Rockman, M.V.1
Wray, G.A.2
-
65
-
-
33746820599
-
Mathematical modeling of polyamine metabolism in mammals
-
Rodriguez-Caso C., Montañez R., Cascante M., Sánchez-Jiménez F., and Medina M.A. Mathematical modeling of polyamine metabolism in mammals. J. Biol. Chem. 281 (2006) 21799-21812
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 21799-21812
-
-
Rodriguez-Caso, C.1
Montañez, R.2
Cascante, M.3
Sánchez-Jiménez, F.4
Medina, M.A.5
-
66
-
-
0007475314
-
Inborn errors of folate and cobalamin metabolism
-
Carmel R., and Jacobsen D.W. (Eds), Cambridge Univ. Press, Cambridge
-
Rosenblatt D. Inborn errors of folate and cobalamin metabolism. In: Carmel R., and Jacobsen D.W. (Eds). Homocysteine in Health and Disease (2001), Cambridge Univ. Press, Cambridge 244-258
-
(2001)
Homocysteine in Health and Disease
, pp. 244-258
-
-
Rosenblatt, D.1
-
67
-
-
0003518480
-
-
John Wiley & Sons, New York
-
Segel I.H. Enzyme Kinetics (1975), John Wiley & Sons, New York
-
(1975)
Enzyme Kinetics
-
-
Segel, I.H.1
-
68
-
-
0024341967
-
Folate pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates-Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cell
-
Seither R.L., Trent D.F., Mikulecky D.C., Rape T.J., and Goldman I.D. Folate pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates-Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cell. J. Biol. Chem. 264 (1989) 17016-17023
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 17016-17023
-
-
Seither, R.L.1
Trent, D.F.2
Mikulecky, D.C.3
Rape, T.J.4
Goldman, I.D.5
-
69
-
-
0002115597
-
Folate chemistry and metabolism
-
Bailey L.B. (Ed), Marcel Dekker, New York
-
Shane B. Folate chemistry and metabolism. In: Bailey L.B. (Ed). Folate in Health and Disease (1995), Marcel Dekker, New York 1-22
-
(1995)
Folate in Health and Disease
, pp. 1-22
-
-
Shane, B.1
-
70
-
-
33845257870
-
Variability and memory of protein levels in human cells
-
Sigal A., Milo R., Cohen A., Naama G.-Z., Klein Y., Liron Y., Rosenfeld N., Danon T., Perzov N., and Alon U. Variability and memory of protein levels in human cells. Nature 444 (2006) 643-646
-
(2006)
Nature
, vol.444
, pp. 643-646
-
-
Sigal, A.1
Milo, R.2
Cohen, A.3
Naama, G.-Z.4
Klein, Y.5
Liron, Y.6
Rosenfeld, N.7
Danon, T.8
Perzov, N.9
Alon, U.10
-
71
-
-
0009877275
-
Methionine loading
-
Carmel R., and Jacobsen D.W. (Eds), Cambridge University Press, Cambridge
-
Silberberg J., and Dudman N. Methionine loading. In: Carmel R., and Jacobsen D.W. (Eds). Homocysteine in Health and Disease (2001), Cambridge University Press, Cambridge 212-219
-
(2001)
Homocysteine in Health and Disease
, pp. 212-219
-
-
Silberberg, J.1
Dudman, N.2
-
72
-
-
0027403342
-
A protein synthesis-dependent increase in E2F1 messenger-RNA correlates with growth regulation of the dihydrofolate reductase promoter
-
Slansky J.E., Li Y., Kaelin W.G., and Farnham P.J. A protein synthesis-dependent increase in E2F1 messenger-RNA correlates with growth regulation of the dihydrofolate reductase promoter. Mol. Cell. Biol. 13 (1993) 1610-1618
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 1610-1618
-
-
Slansky, J.E.1
Li, Y.2
Kaelin, W.G.3
Farnham, P.J.4
-
73
-
-
0025676019
-
Activity of an NAD-dependent 5,10-methylenetatrahydrofolate dehydrogenase in normal tissue, neoplastic cells, and oncogene-transformed cells
-
Smith G.K., Banks S.D., Monaco T., Rigual R., Duch D.S., Mullin R.J., and Huber B.E. Activity of an NAD-dependent 5,10-methylenetatrahydrofolate dehydrogenase in normal tissue, neoplastic cells, and oncogene-transformed cells. Arch. Biochem. Biophys. 283 (1990) 367-371
-
(1990)
Arch. Biochem. Biophys.
, vol.283
, pp. 367-371
-
-
Smith, G.K.1
Banks, S.D.2
Monaco, T.3
Rigual, R.4
Duch, D.S.5
Mullin, R.J.6
Huber, B.E.7
-
74
-
-
0342369387
-
Effect of high dose folic acid therapy on hyperhomocysteinemia in hemodialysis patients: Results of the Vienna Multicenter Study
-
Sunder-Plassman G., Foedinger M., Buchmayer H., Papagiannopoulos M., Wojcik J., Kletzmayr J., Enzenberger B., Janat A.O., Winkelmayer W.C., Paul G., Auinger M., Barnas U., et al. Effect of high dose folic acid therapy on hyperhomocysteinemia in hemodialysis patients: Results of the Vienna Multicenter Study. J. Am. Soc. Nephrol. 11 (2000) 1106-1116
-
(2000)
J. Am. Soc. Nephrol.
, vol.11
, pp. 1106-1116
-
-
Sunder-Plassman, G.1
Foedinger, M.2
Buchmayer, H.3
Papagiannopoulos, M.4
Wojcik, J.5
Kletzmayr, J.6
Enzenberger, B.7
Janat, A.O.8
Winkelmayer, W.C.9
Paul, G.10
Auinger, M.11
Barnas, U.12
-
75
-
-
31544483014
-
Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenpausal women
-
Troen A.M., Mitchell B., Sorensen B., Wener M.H., Johnston A., Wood B., Selhub J., McTiernan A., Yasui Y., Potter J.D., and Ulrich C.M. Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenpausal women. J. Nutr. 136 (2006) 189-194
-
(2006)
J. Nutr.
, vol.136
, pp. 189-194
-
-
Troen, A.M.1
Mitchell, B.2
Sorensen, B.3
Wener, M.H.4
Johnston, A.5
Wood, B.6
Selhub, J.7
McTiernan, A.8
Yasui, Y.9
Potter, J.D.10
Ulrich, C.M.11
-
76
-
-
51849141964
-
Mathematical modeling of folate metabolism: Predicted effects of genetic polymorphisms on mechanisms and biomarkers relevant to carcinogenesis
-
(in press)
-
Ulrich C.M., Neuhouser M., Lui A.Y., Boynton A., Gregory III J.F., Shane B., James S.J., Reed M.C., and Nijhout H.F. Mathematical modeling of folate metabolism: Predicted effects of genetic polymorphisms on mechanisms and biomarkers relevant to carcinogenesis. Cancer Epidemiol. Biomark. Prev. (2008) (in press)
-
(2008)
Cancer Epidemiol. Biomark. Prev.
-
-
Ulrich, C.M.1
Neuhouser, M.2
Lui, A.Y.3
Boynton, A.4
Gregory III, J.F.5
Shane, B.6
James, S.J.7
Reed, M.C.8
Nijhout, H.F.9
-
77
-
-
0018920516
-
Mathematical description and investigation of the principles of functioning in the folic acid cycle
-
Vorontzov I.N., Greshilov M.M., Belousova A.K., and Gerasimova G.K. Mathematical description and investigation of the principles of functioning in the folic acid cycle. Biokhimiya 45 (1980) 83-97
-
(1980)
Biokhimiya
, vol.45
, pp. 83-97
-
-
Vorontzov, I.N.1
Greshilov, M.M.2
Belousova, A.K.3
Gerasimova, G.K.4
-
78
-
-
0028960161
-
An inverted repeat motif stabilizes binding of E2F and enhances transcription of the dihydrofolate reductase gene
-
Wade M., Blake M.C., Jambou R.C., Helin K., Harlow E., and Azizkhan J.C. An inverted repeat motif stabilizes binding of E2F and enhances transcription of the dihydrofolate reductase gene. J. Biol. Chem. 270 (1995) 9783-9791
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 9783-9791
-
-
Wade, M.1
Blake, M.C.2
Jambou, R.C.3
Helin, K.4
Harlow, E.5
Azizkhan, J.C.6
-
80
-
-
0002942853
-
Biochemical role of folate in cell metabolism
-
Bailey L.B. (Ed), Marcel Dekker, New York
-
Wagner C. Biochemical role of folate in cell metabolism. In: Bailey L.B. (Ed). Folate in Health and Disease (1995), Marcel Dekker, New York 23-42
-
(1995)
Folate in Health and Disease
, pp. 23-42
-
-
Wagner, C.1
-
81
-
-
0021867328
-
Inhibition of glycine N-methyltransferase activity by folate derivatives: Implications for regulation of methyl group metabolism
-
Wagner C., Briggs W.T., and Cook R.J. Inhibition of glycine N-methyltransferase activity by folate derivatives: Implications for regulation of methyl group metabolism. Biochem. Biophys. Res. Comm. 27 (1985) 746-752
-
(1985)
Biochem. Biophys. Res. Comm.
, vol.27
, pp. 746-752
-
-
Wagner, C.1
Briggs, W.T.2
Cook, R.J.3
-
82
-
-
0015881295
-
Mathematical simulation of the interaction of drugs that inhibit deoxyribonucleic acid biosynthesis
-
Werkheiser W.C., Grindey G.B., Moran R.G., and Nichol C.A. Mathematical simulation of the interaction of drugs that inhibit deoxyribonucleic acid biosynthesis. Molec. Pharmacol. 9 (1973) 320-329
-
(1973)
Molec. Pharmacol.
, vol.9
, pp. 320-329
-
-
Werkheiser, W.C.1
Grindey, G.B.2
Moran, R.G.3
Nichol, C.A.4
-
83
-
-
34547101719
-
Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway
-
Woeller C.F., Anderson D.D., Doletha, Szebenyi M.E., and Stover P.J. Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway. J. Biol. Chem. 282 (2007) 17623-17631
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 17623-17631
-
-
Woeller, C.F.1
Anderson, D.D.2
Doletha3
Szebenyi, M.E.4
Stover, P.J.5
-
84
-
-
0035909980
-
Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase
-
Yamada K., Chen Z., Rozen R., and Matthews R.G. Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase. Proc. Nat. Acad. Sci. USA 98 (2001) 14853-14858
-
(2001)
Proc. Nat. Acad. Sci. USA
, vol.98
, pp. 14853-14858
-
-
Yamada, K.1
Chen, Z.2
Rozen, R.3
Matthews, R.G.4
-
85
-
-
0037119584
-
Allelic variation in human gene expression
-
Yan H., Yuan W., Velculescu V.E., Vogelstein B., and Kinzler K.W. Allelic variation in human gene expression. Science 297 (2002) 1143
-
(2002)
Science
, vol.297
, pp. 1143
-
-
Yan, H.1
Yuan, W.2
Velculescu, V.E.3
Vogelstein, B.4
Kinzler, K.W.5
-
86
-
-
0026459646
-
Purification and properties of pancreatic glycine N-methyltransferase
-
Yeo E.J., and Wagner C. Purification and properties of pancreatic glycine N-methyltransferase. J. Biol. Chem. 267 (1992) 24669-24674
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 24669-24674
-
-
Yeo, E.J.1
Wagner, C.2
|