C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Nature

Volumn 458, Issue 7239, 2009, Pages 762-765

  Gao, Ping ^a   Tchernyshyov, Irina ^a   Chang, Tsung Cheng ^a   Lee, Yun Sil ^a   Kita, Kayoko ^b   Ochi, Takafumi ^b   Zeller, Karen I ^a   De Marzo, Angelo M ^a   Van Eyk, Jennifer E ^a   Mendell, Joshua T ^a   Dang, Chi V ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TEIKYO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; GLUCOSE; GLUTAMIC ACID; GLUTAMINASE; GLUTAMINE; GLUTATHIONE; MICRORNA; MITOCHONDRIAL ENZYME; MITOCHONDRIAL PROTEIN; MYC PROTEIN; OXALOACETIC ACID; PROTEIN TFAM; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; MYC PROTEIN, HUMAN;

AMINO ACID; CANCER; CYTOLOGY; ENZYME ACTIVITY; GENE EXPRESSION; METABOLISM;

AMINO ACID METABOLISM; ARTICLE; B CELL LYMPHOMA; CANCER CELL; CELL DEATH; CELL PROLIFERATION; CITRIC ACID CYCLE; CONTROLLED STUDY; ENZYME METABOLISM; GENE; GENE REPRESSION; GLUCOSE METABOLISM; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; MIR 23A GENE; MIR 23B GENE; MITOCHONDRION; MUTAGENESIS; ONCOGENE MYC; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEOMICS; RNA INTERFERENCE; TRANSCRIPTION REGULATION; 3' UNTRANSLATED REGION; ENZYMOLOGY; GENE EXPRESSION REGULATION; METABOLISM; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMINASE; GLUTAMINE; HUMANS; MICRORNAS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-MYC;

EID: 64749116346     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature07823     Document Type: Article

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