-
1
-
-
37549048249
-
The BCL-2 protein family: Opposing activities that mediate cell death
-
10.1038/nrm2308 1:CAS:528:DC%2BD2sXhsVKrsrrP 18097445
-
R Youle A Strasser 2008 The BCL-2 protein family: opposing activities that mediate cell death Nat Rev Mol Cell Biol 9 47 59 10.1038/nrm2308 1:CAS:528:DC%2BD2sXhsVKrsrrP 18097445
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.1
Strasser, A.2
-
2
-
-
0023786047
-
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
-
10.1038/335440a0 1:CAS:528:DyaL1MXlt1alsA%3D%3D 3262202
-
DL Vaux S Cory JM Adams 1988 Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells Nature 335 440 442 10.1038/335440a0 1:CAS:528:DyaL1MXlt1alsA%3D%3D 3262202
-
(1988)
Nature
, vol.335
, pp. 440-442
-
-
Vaux, D.L.1
Cory, S.2
Adams, J.M.3
-
3
-
-
0026582702
-
Caenorhabditis elegans gene ced-9 protects cells from programmed cell death
-
10.1038/356494a0 1:CAS:528:DyaK38XisV2rtLs%3D 1560823
-
MO Hengartner RE Ellis HR Horvitz 1992 Caenorhabditis elegans gene ced-9 protects cells from programmed cell death Nature 356 494 499 10.1038/356494a0 1:CAS:528:DyaK38XisV2rtLs%3D 1560823
-
(1992)
Nature
, vol.356
, pp. 494-499
-
-
Hengartner, M.O.1
Ellis, R.E.2
Horvitz, H.R.3
-
4
-
-
0034508217
-
The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues
-
DOI 10.1016/S1097-2765(00)00136-2
-
T Lindsten AJ Ross A King WX Zong JC Rathmell HA Shiels E Ulrich KG Waymire P Mahar K Frauwirth Y Chen M Wei VM Eng DM Adelman MC Simon A Ma JA Golden G Evan SJ Korsmeyer GR MacGregor CB Thompson 2000 The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues Mol Cell 6 1389 1399 10.1016/S1097-2765(00) 00136-2 1:CAS:528:DC%2BD3MXlvFagsg%3D%3D 11163212 (Pubitemid 32045931)
-
(2000)
Molecular Cell
, vol.6
, Issue.6
, pp. 1389-1399
-
-
Lindsten, T.1
Ross, A.J.2
King, A.3
Zong, W.-X.4
Rathmell, J.C.5
Shiels, H.A.6
Ulrich, E.7
Waymire, K.G.8
Mahar, P.9
Frauwirth, K.10
Chen, Y.11
Wei, M.12
Eng, V.M.13
Adelman, D.M.14
Simon M.Celeste15
Ma, A.16
Golden, J.A.17
Evan, G.18
Korsmeyer, S.J.19
MacGregor, G.R.20
Thompson, C.B.21
more..
-
5
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
DOI 10.1152/physrev.00013.2006
-
G Kroemer L Galluzzi C Brenner 2007 Mitochondrial membrane permeabilization in cell death Physiol Rev 87 99 163 10.1152/physrev.00013.2006 1:CAS:528:DC%2BD2sXitVahu7k%3D 17237344 (Pubitemid 46209992)
-
(2007)
Physiological Reviews
, vol.87
, Issue.1
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
6
-
-
58149299435
-
Baxβ: A constitutively active human Bax isoform that is under tight regulatory control by the proteasomal degradation mechanism
-
10.1016/j.molcel.2008.11.025 1:CAS:528:DC%2BD1MXhtFOitrk%3D 19150424
-
N Fu S Sukumaran S Kerk V Yu 2009 Baxβ: a constitutively active human Bax isoform that is under tight regulatory control by the proteasomal degradation mechanism Mol Cell 33 15 29 10.1016/j.molcel.2008.11.025 1:CAS:528:DC%2BD1MXhtFOitrk%3D 19150424
-
(2009)
Mol Cell
, vol.33
, pp. 15-29
-
-
Fu, N.1
Sukumaran, S.2
Kerk, S.3
Yu, V.4
-
7
-
-
43049105074
-
To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions
-
DOI 10.1016/j.molcel.2008.04.005, PII S1097276508002657
-
G Dewson T Kratina H Sim H Puthalakath J Adams P Colman R Kluck 2008 To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3: groove interactions Mol Cell 30 369 380 10.1016/j.molcel.2008.04.005 1:CAS:528:DC%2BD1cXmtFaktLY%3D 18471982 (Pubitemid 351626944)
-
(2008)
Molecular Cell
, vol.30
, Issue.3
, pp. 369-380
-
-
Dewson, G.1
Kratina, T.2
Sim, H.W.3
Puthalakath, H.4
Adams, J.M.5
Colman, P.M.6
Kluck, R.M.7
-
8
-
-
41149152733
-
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
-
10.1016/j.tcb.2008.01.007 1:CAS:528:DC%2BD1cXktlGksbs%3D 18314333
-
J Chipuk D Green 2008 How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? Trends Cell Biol 18 157 164 10.1016/j.tcb.2008.01.007 1:CAS:528:DC%2BD1cXktlGksbs%3D 18314333
-
(2008)
Trends Cell Biol
, vol.18
, pp. 157-164
-
-
Chipuk, J.1
Green, D.2
-
9
-
-
33846964621
-
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
-
10.1126/science.1133289 1:CAS:528:DC%2BD2sXhsVShsL4%3D 17289999
-
SN Willis JI Fletcher T Kaufmann MF van Delft L Chen PE Czabotar H Ierino EF Lee WD Fairlie P Bouillet A Strasser RM Kluck JM Adams DC Huang 2007 Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak Science 315 856 859 10.1126/science.1133289 1:CAS:528:DC%2BD2sXhsVShsL4%3D 17289999
-
(2007)
Science
, vol.315
, pp. 856-859
-
-
Willis, S.N.1
Fletcher, J.I.2
Kaufmann, T.3
Van Delft, M.F.4
Chen, L.5
Czabotar, P.E.6
Ierino, H.7
Lee, E.F.8
Fairlie, W.D.9
Bouillet, P.10
Strasser, A.11
Kluck, R.M.12
Adams, J.M.13
Huang, D.C.14
-
10
-
-
57149135309
-
Membrane binding by tBid Initiates an ordered series of events culminating in membrane permeabilization by Bax
-
10.1016/j.cell.2008.11.010 1:CAS:528:DC%2BD1MXnslOq 19062087
-
J Lovell L Billen S Bindner A Shamasdin C Fradin B Leber D Andrews 2008 Membrane binding by tBid Initiates an ordered series of events culminating in membrane permeabilization by Bax Cell 135 1074 1084 10.1016/j.cell.2008.11.010 1:CAS:528:DC%2BD1MXnslOq 19062087
-
(2008)
Cell
, vol.135
, pp. 1074-1084
-
-
Lovell, J.1
Billen, L.2
Bindner, S.3
Shamasdin, A.4
Fradin, C.5
Leber, B.6
Andrews, D.7
-
11
-
-
0842278331
-
Direct activation of bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
DOI 10.1126/science.1092734
-
JE Chipuk T Kuwana L Bouchier-Hayes NM Droin DD Newmeyer M Schuler DR Green 2004 Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis Science 303 1010 1014 10.1126/science.1092734 1:CAS:528:DC%2BD2cXhtlWnu7o%3D 14963330 (Pubitemid 38209704)
-
(2004)
Science
, vol.303
, Issue.5660
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
12
-
-
2342553892
-
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex
-
DOI 10.1038/ncb1123
-
JI Leu P Dumont M Hafey ME Murphy DL George 2004 Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex Nat Cell Biol 6 443 450 10.1038/ncb1123 1:CAS:528:DC%2BD2cXjsFSlt78%3D 15077116 (Pubitemid 38607505)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.5
, pp. 443-450
-
-
Leu, J.I.-J.1
Dumont, P.2
Hafey, M.3
Murphy, M.E.4
George, D.L.5
-
13
-
-
54549114986
-
BAX activation is initiated at a novel interaction site
-
10.1038/nature07396 1:CAS:528:DC%2BD1cXht1yju7rL 18948948
-
E Gavathiotis M Suzuki M Davis K Pitter G Bird S Katz H Tu H Kim EH Cheng N Tjandra L Walensky 2008 BAX activation is initiated at a novel interaction site Nature 455 1076 1081 10.1038/nature07396 1:CAS:528:DC%2BD1cXht1yju7rL 18948948
-
(2008)
Nature
, vol.455
, pp. 1076-1081
-
-
Gavathiotis, E.1
Suzuki, M.2
Davis, M.3
Pitter, K.4
Bird, G.5
Katz, S.6
Tu, H.7
Kim, H.8
Cheng, E.H.9
Tjandra, N.10
Walensky, L.11
-
14
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
DOI 10.1126/science.288.5468.1053
-
E Oda R Ohki H Murasawa J Nemoto T Shibue T Yamashita T Tokino T Taniguchi N Tanaka 2000 Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis Science 288 1053 1058 10.1126/science.288.5468.1053 1:CAS:528:DC%2BD3cXjsVSnsbg%3D 10807576 (Pubitemid 30324238)
-
(2000)
Science
, vol.288
, Issue.5468
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
15
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
DOI 10.1016/S1097-2765(01)00214-3
-
K Nakano KH Vousden 2001 PUMA, a novel proapoptotic gene, is induced by p53 Mol Cell 7 683 694 10.1016/S1097-2765(01)00214-3 1:CAS:528: DC%2BD3MXivVCmtLk%3D 11463392 (Pubitemid 32706359)
-
(2001)
Molecular Cell
, vol.7
, Issue.3
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
16
-
-
0034609737
-
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
-
10.1016/S0960-9822(00)00728-4 1:CAS:528:DC%2BD3cXotVSrtLs%3D 11050388
-
PF Dijkers RH Medema JW Lammers L Koenderman PJ Coffer 2000 Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1 Curr Biol 10 1201 1204 10.1016/S0960-9822(00)00728- 4 1:CAS:528:DC%2BD3cXotVSrtLs%3D 11050388
-
(2000)
Curr Biol
, vol.10
, pp. 1201-1204
-
-
Dijkers, P.F.1
Medema, R.H.2
Lammers, J.W.3
Koenderman, L.4
Coffer, P.J.5
-
17
-
-
34250758642
-
ER stress triggers apoptosis by activating BH3-only protein bim
-
DOI 10.1016/j.cell.2007.04.027, PII S0092867407005375
-
H Puthalakath L O'reilly P Gunn L Lee P Kelly N Huntington P Hughes E Michalak J Mckimm-Breschkin N Motoyama T Gotoh S Akira P Bouillet A Strasser 2007 ER stress triggers apoptosis by activating BH3-only protein Bim Cell 129 1337 1349 10.1016/j.cell.2007.04.027 1:CAS:528:DC%2BD2sXotV2hsLw%3D 17604722 (Pubitemid 46962086)
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1337-1349
-
-
Puthalakath, H.1
O'Reilly, L.A.2
Gunn, P.3
Lee, L.4
Kelly, P.N.5
Huntington, N.D.6
Hughes, P.D.7
Michalak, E.M.8
McKimm-Breschkin, J.9
Motoyama, N.10
Gotoh, T.11
Akira, S.12
Bouillet, P.13
Strasser, A.14
-
18
-
-
42049091619
-
Unique biology of Mcl-1: Therapeutic oportunities in cancer
-
DOI 10.2174/156652408783769580
-
MR Warr GC Shore 2008 Unique biology of Mcl-1: therapeutic opportunities in cancer Curr Mol Med 8 138 147 10.2174/156652408783769580 1:CAS:528: DC%2BD1cXktlWgsLc%3D 18336294 (Pubitemid 351516833)
-
(2008)
Current Molecular Medicine
, vol.8
, Issue.2
, pp. 138-147
-
-
Warr, M.R.1
Shore, G.C.2
-
19
-
-
37249042829
-
Dissecting eIF4E action in tumorigenesis
-
DOI 10.1101/gad.1604407
-
H Wendel R Silva A Malina J Mills H Zhu T Ueda R Watanabe-Fukunaga R Fukunaga J Teruya-Feldstein J Pelletier S Lowe 2007 Dissecting eIF4E action in tumorigenesis Genes Dev 21 3232 3237 10.1101/gad.1604407 1:CAS:528: DC%2BD2sXhsVOrsb7K 18055695 (Pubitemid 350277750)
-
(2007)
Genes and Development
, vol.21
, Issue.24
, pp. 3232-3237
-
-
Wendel, H.-G.1
Silva, R.L.A.2
Malina, A.3
Mills, J.R.4
Zhu, H.5
Ueda, T.6
Watanabe-Fukunaga, R.7
Fukunaga, R.8
Teruya-Feldstein, J.9
Pelletier, J.10
Lowe, S.W.11
-
20
-
-
33644855216
-
Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
-
DOI 10.1016/j.molcel.2006.02.009, PII S1097276506001110
-
U Maurer C Charvet AS Wagman E Dejardin DR Green 2006 Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1 Mol Cell 21 749 760 10.1016/j.molcel.2006.02.009 1:CAS:528:DC%2BD28XjtVyju74%3D 16543145 (Pubitemid 43376126)
-
(2006)
Molecular Cell
, vol.21
, Issue.6
, pp. 749-760
-
-
Maurer, U.1
Charvet, C.2
Wagman, A.S.3
Dejardin, E.4
Green, D.R.5
-
21
-
-
3142754413
-
BCL-2 translation is mediated via internal ribosome entry during cell stress
-
DOI 10.1074/jbc.M402727200
-
KW Sherrill MP Byrd ME Van Eden RE Lloyd 2004 BCL-2 translation is mediated via internal ribosome entry during cell stress J Biol Chem 279 29066 29074 10.1074/jbc.M402727200 1:CAS:528:DC%2BD2cXlsVCntb4%3D 15123638 (Pubitemid 38915777)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.28
, pp. 29066-29074
-
-
Sherrill, K.W.1
Byrd, M.P.2
Van Eden, M.E.3
Lloyd, R.E.4
-
22
-
-
35649001888
-
A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer
-
DOI 10.1016/j.molcel.2007.10.019, PII S1097276507007022
-
S Braunstein K Karpisheva C Pola J Goldberg T Hochman H Yee J Cangiarella R Arju SC Formenti RJ Schneider 2007 A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer Mol Cell 28 501 512 10.1016/j.molcel.2007.10.019 1:CAS:528:DC%2BD2sXhtlWitrbP 17996713 (Pubitemid 350030573)
-
(2007)
Molecular Cell
, vol.28
, Issue.3
, pp. 501-512
-
-
Braunstein, S.1
Karpisheva, K.2
Pola, C.3
Goldberg, J.4
Hochman, T.5
Yee, H.6
Cangiarella, J.7
Arju, R.8
Formenti, S.C.9
Schneider, R.J.10
-
23
-
-
77953025882
-
Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation
-
in press
-
Pradelli LA, Beneteau M, Chauvin C, Jacquin MA, Marchetti S, Munoz-Pinedo C, Auberger P, Pende M, Ricci JE (2009) Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation. Oncogene (in press)
-
(2009)
Oncogene
-
-
Pradelli, L.A.1
Beneteau, M.2
Chauvin, C.3
Jacquin, M.A.4
Marchetti, S.5
Munoz-Pinedo, C.6
Auberger, P.7
Pende, M.8
Ricci, J.E.9
-
24
-
-
0034614637
-
The hallmarks of cancer
-
10.1016/S0092-8674(00)81683-9 1:CAS:528:DC%2BD3cXks1CktA%3D%3D 10647931
-
D Hanahan RA Weinberg 2000 The hallmarks of cancer Cell 100 57 70 10.1016/S0092-8674(00)81683-9 1:CAS:528:DC%2BD3cXks1CktA%3D%3D 10647931
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
25
-
-
33845994359
-
Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737
-
DOI 10.1172/JCI28281
-
V Del Gaizo Moore JR Brown M Certo TM Love CD Novina A Letai 2007 Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737 J Clin Invest 117 112 121 10.1172/JCI28281 1:CAS:528:DC%2BD2sXmvV2qsQ%3D%3D 17200714 (Pubitemid 46048458)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 112-121
-
-
Moore, V.D.G.1
Brown, J.R.2
Certo, M.3
Love, T.M.4
Novina, C.D.5
Letai, A.6
-
26
-
-
33750628289
-
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
-
DOI 10.1016/j.ccr.2006.10.006, PII S1535610806003138
-
M Konopleva R Contractor T Tsao I Samudio PP Ruvolo S Kitada X Deng D Zhai YX Shi T Sneed M Verhaegen M Soengas VR Ruvolo T McQueen WD Schober JC Watt T Jiffar X Ling FC Marini D Harris M Dietrich Z Estrov J McCubrey WS May JC Reed M Andreeff 2006 Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia Cancer Cell 10 375 388 10.1016/j.ccr.2006.10.006 1:CAS:528:DC%2BD28Xht1Glu7nJ 17097560 (Pubitemid 44693472)
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 375-388
-
-
Konopleva, M.1
Contractor, R.2
Tsao, T.3
Samudio, I.4
Ruvolo, P.P.5
Kitada, S.6
Deng, X.7
Zhai, D.8
Shi, Y.-X.9
Sneed, T.10
Verhaegen, M.11
Soengas, M.12
Ruvolo, V.R.13
McQueen, T.14
Schober, W.D.15
Watt, J.C.16
Jiffar, T.17
Ling, X.18
Marini, F.C.19
Harris, D.20
Dietrich, M.21
Estrov, Z.22
McCubrey, J.23
May, W.S.24
Reed, J.C.25
Andreeff, M.26
more..
-
27
-
-
34547603628
-
BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents
-
DOI 10.1016/j.ccr.2007.07.001, PII S1535610807002000
-
J Deng N Carlson K Takeyama P Dal Cin M Shipp A Letai 2007 BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents Cancer Cell 12 171 185 10.1016/j.ccr.2007.07.001 1:CAS:528:DC%2BD2sXps1art7o%3D 17692808 (Pubitemid 47199122)
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 171-185
-
-
Deng, J.1
Carlson, N.2
Takeyama, K.3
Dal Cin, P.4
Shipp, M.5
Letai, A.6
-
28
-
-
59649092928
-
Bad targets the permeability transition pore independent of Bax or Bak to switch between Ca2+-dependent cell survival and death
-
10.1016/j.molcel.2009.01.018 1:CAS:528:DC%2BD1MXltFSnur0%3D 19217411
-
S Roy M Madesh E Davies B Antonsson N Danial G Hajnóczky 2009 Bad targets the permeability transition pore independent of Bax or Bak to switch between Ca2+-dependent cell survival and death Mol Cell 33 377 388 10.1016/j.molcel.2009.01.018 1:CAS:528:DC%2BD1MXltFSnur0%3D 19217411
-
(2009)
Mol Cell
, vol.33
, pp. 377-388
-
-
Roy, S.1
Madesh, M.2
Davies, E.3
Antonsson, B.4
Danial, N.5
Hajnóczky, G.6
-
29
-
-
34247895697
-
Voltage-dependent anion channels are dispensable for mitochondrial- dependent cell death
-
DOI 10.1038/ncb1575, PII NCB1575
-
CP Baines RA Kaiser T Sheiko WJ Craigen JD Molkentin 2007 Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death Nat Cell Biol 9 550 555 10.1038/ncb1575 1:CAS:528: DC%2BD2sXkslyiur8%3D 17417626 (Pubitemid 46696536)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.5
, pp. 550-555
-
-
Baines, C.P.1
Kaiser, R.A.2
Sheiko, T.3
Craigen, W.J.4
Molkentin, J.D.5
-
30
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
10.1016/S0092-8674(00)00008-8 1:CAS:528:DC%2BD3cXkvFCrsbc%3D 10929711
-
C Du M Fang Y Li L Li X Wang 2000 Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition Cell 102 33 42 10.1016/S0092-8674(00)00008-8 1:CAS:528:DC%2BD3cXkvFCrsbc%3D 10929711
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
31
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
10.1016/S0092-8674(00)00009-X 1:CAS:528:DC%2BD3cXkvFCrtr4%3D 10929712
-
AM Verhagen PG Ekert M Pakusch J Silke LM Connolly GE Reid RL Moritz RJ Simpson DL Vaux 2000 Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins Cell 102 43 53 10.1016/S0092-8674(00)00009-X 1:CAS:528:DC%2BD3cXkvFCrtr4%3D 10929712
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
Moritz, R.L.7
Simpson, R.J.8
Vaux, D.L.9
-
32
-
-
4444243683
-
A small molecule smac mimic potentiates TRAIL- and TNFα-mediated cell death
-
DOI 10.1126/science.1098231
-
L Li RM Thomas H Suzuki JK De Brabander X Wang PG Harran 2004 A small molecule Smac mimic potentiates TRAIL-and TNFalpha-mediated cell death Science 305 1471 1474 10.1126/science.1098231 1:CAS:528:DC%2BD2cXntFartL8%3D 15353805 (Pubitemid 39167668)
-
(2004)
Science
, vol.305
, Issue.5689
, pp. 1471-1474
-
-
Li, L.1
Thomas, R.M.2
Suzuki, H.3
De Brabander, J.K.4
Wang, X.5
Harran, P.G.6
-
33
-
-
33846878524
-
Targeting mitochondrial factor Smac/DIABLO as therapy for multiple myeloma (MM)
-
DOI 10.1182/blood-2006-04-015149
-
D Chauhan P Neri M Velankar K Podar T Hideshima M Fulciniti P Tassone N Raje C Mitsiades N Mitsiades P Richardson L Zawel M Tran N Munshi KC Anderson 2007 Targeting mitochondrial factor Smac/DIABLO as therapy for multiple myeloma (MM) Blood 109 1220 1227 10.1182/blood-2006-04-015149 1:CAS:528: DC%2BD2sXjtFertb4%3D 17032924 (Pubitemid 46220671)
-
(2007)
Blood
, vol.109
, Issue.3
, pp. 1220-1227
-
-
Chauhan, D.1
Neri, P.2
Velankar, M.3
Podar, K.4
Hideshima, T.5
Fulciniti, M.6
Tassone, P.7
Raje, N.8
Mitsiades, C.9
Mitsiades, N.10
Richardson, P.11
Zawel, L.12
Tran, M.13
Munshi, N.14
Anderson, K.C.15
-
34
-
-
36048982462
-
Smac mimetics and TNFα: A dangerous liaison?
-
DOI 10.1016/j.cell.2007.10.042, PII S0092867407013967
-
H Wu J Tschopp SC Lin 2007 Smac mimetics and TNFalpha: a dangerous liaison? Cell 131 655 658 10.1016/j.cell.2007.10.042 1:CAS:528: DC%2BD2sXhsVSgurzK 18022360 (Pubitemid 350087206)
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 655-658
-
-
Wu, H.1
Tschopp, J.2
Lin, S.-C.3
-
35
-
-
33846251849
-
Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs
-
DOI 10.1038/sj.cdd.4402001, PII 4402001
-
AM Verhagen TK Kratina CJ Hawkins J Silke PG Ekert DL Vaux 2007 Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs Cell Death Differ 14 348 357 10.1038/sj.cdd. 4402001 1:CAS:528:DC%2BD2sXkslChsw%3D%3D 16794601 (Pubitemid 46092237)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.2
, pp. 348-357
-
-
Verhagen, A.M.1
Kratina, T.K.2
Hawkins, C.J.3
Silke, J.4
Ekert, P.G.5
Vaux, D.L.6
-
36
-
-
0035897408
-
Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process
-
DOI 10.1083/jcb.153.2.319
-
NJ Waterhouse JC Goldstein O von Ahsen M Schuler DD Newmeyer DR Green 2001 Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process J Cell Biol 153 319 328 10.1083/jcb.153.2.319 1:CAS:528:DC%2BD3MXivFOiurc%3D 11309413 (Pubitemid 34280218)
-
(2001)
Journal of Cell Biology
, vol.153
, Issue.2
, pp. 319-328
-
-
Waterhouse, N.J.1
Goldstein, J.C.2
Von Ahsen, O.3
Schuler, M.4
Newmeyer, D.D.5
Green, D.R.6
-
37
-
-
2942581328
-
Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain
-
DOI 10.1016/j.cell.2004.05.008, PII S0092867404004969
-
JE Ricci C Munoz-Pinedo P Fitzgerald B Bailly-Maitre GA Perkins N Yadava IE Scheffler MH Ellisman DR Green 2004 Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain Cell 117 773 786 10.1016/j.cell.2004.05.008 1:CAS:528:DC%2BD2cXltlKitrs%3D 15186778 (Pubitemid 38748893)
-
(2004)
Cell
, vol.117
, Issue.6
, pp. 773-786
-
-
Ricci, J.-E.1
Munoz-Pinedo, C.2
Fitzgerald, P.3
Bailly-Maitre, B.4
Perkins, G.A.5
Yadava, N.6
Scheffler, I.E.7
Ellisman, M.H.8
Green, D.R.9
-
38
-
-
0033151801
-
Inhibition of caspase activity does not prevent the signaling phase of apoptosis in prostate cancer cells
-
DOI 10.1002/(SICI)1097-0045(19990601)39:4<269::AID-PROS7>3.0.CO;2-F
-
SR Denmeade XS Lin B Tombal JT Isaacs 1999 Inhibition of caspase activity does not prevent the signaling phase of apoptosis in prostate cancer cells Prostate 39 269 279 10.1002/(SICI)1097-0045(19990601)39:4<269::AID- PROS7>3.0.CO;2-F 1:CAS:528:DyaK1MXjslyjsb4%3D 10344216 (Pubitemid 29244501)
-
(1999)
Prostate
, vol.39
, Issue.4
, pp. 269-279
-
-
Denmeade, S.R.1
Lin, X.S.2
Tombal, B.3
Isaacs, J.T.4
-
39
-
-
0032545372
-
Bcl-2 prevents caspase-independent cell death
-
DOI 10.1074/jbc.273.51.34272
-
S Okuno S Shimizu T Ito M Nomura E Hamada Y Tsujimoto H Matsuda 1998 Bcl-2 prevents caspase-independent cell death J Biol Chem 273 34272 34277 10.1074/jbc.273.51.34272 1:CAS:528:DyaK1MXntlWi 9852091 (Pubitemid 29008903)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.51
, pp. 34272-34277
-
-
Okuno, S.-I.1
Shimizu, S.2
Ito, T.3
Nomura, M.4
Hamada, E.5
Tsujimoto, Y.6
Matsuda, H.7
-
40
-
-
3543011331
-
Upstream regulatory role for XIAP in receptor-mediated apoptosis
-
DOI 10.1128/MCB.24.16.7003-7014.2004
-
JC Wilkinson E Cepero LH Boise CS Duckett 2004 Upstream regulatory role for XIAP in receptor-mediated apoptosis Mol Cell Biol 24 7003 7014 10.1128/MCB.24.16.7003-7014.2004 1:CAS:528:DC%2BD2cXmtlOjtr8%3D 15282301 (Pubitemid 39014428)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.16
, pp. 7003-7014
-
-
Wilkinson, J.C.1
Cepero, E.2
Boise, L.H.3
Duckett, C.S.4
-
41
-
-
0032493870
-
Differential requirement for Caspase 9 in apoptotic pathways in vivo
-
DOI 10.1016/S0092-8674(00)81477-4
-
R Hakem A Hakem GS Duncan JT Henderson M Woo MS Soengas A Elia JL de la Pompa D Kagi W Khoo J Potter R Yoshida SA Kaufman SW Lowe JM Penninger TW Mak 1998 Differential requirement for caspase 9 in apoptotic pathways in vivo Cell 94 339 352 10.1016/S0092-8674(00)81477-4 1:CAS:528:DyaK1cXlsVWjs7s%3D 9708736 (Pubitemid 28376078)
-
(1998)
Cell
, vol.94
, Issue.3
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
Henderson, J.T.4
Woo, M.5
Soengas, M.S.6
Elia, A.7
De La Pompa, J.L.8
Kagi, D.9
Khoo, W.10
Potter, J.11
Yoshida, R.12
Kaufman, S.A.13
Lowe, S.W.14
Penninger, J.M.15
Mak, T.W.16
-
42
-
-
0032493910
-
Reduced apoptosis and cytochrome C-mediated caspase activation in mice lacking Caspase 9
-
DOI 10.1016/S0092-8674(00)81476-2
-
K Kuida TF Haydar CY Kuan Y Gu C Taya H Karasuyama MS Su P Rakic RA Flavell 1998 Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9 Cell 94 325 337 10.1016/S0092-8674(00)81476-2 1:CAS:528:DyaK1cXlsVWjs7o%3D 9708735 (Pubitemid 28376077)
-
(1998)
Cell
, vol.94
, Issue.3
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.-Y.3
Gu, Y.4
Taya, C.5
Karasuyama, H.6
Su, M.S.-S.7
Rakic, P.8
Flavell, R.A.9
-
43
-
-
0034640102
-
Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis
-
10.1016/S0092-8674(00)80849-1 1:CAS:528:DC%2BD3cXjsFeku74%3D 10830166
-
K Li Y Li JM Shelton JA Richardson E Spencer ZJ Chen X Wang RS Williams 2000 Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis Cell 101 389 399 10.1016/S0092-8674(00)80849-1 1:CAS:528:DC%2BD3cXjsFeku74%3D 10830166
-
(2000)
Cell
, vol.101
, pp. 389-399
-
-
Li, K.1
Li, Y.2
Shelton, J.M.3
Richardson, J.A.4
Spencer, E.5
Chen, Z.J.6
Wang, X.7
Williams, R.S.8
-
44
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
DOI 10.1016/S0092-8674(00)81733-X
-
H Yoshida YY Kong R Yoshida AJ Elia A Hakem R Hakem JM Penninger TW Mak 1998 Apaf1 is required for mitochondrial pathways of apoptosis and brain development Cell 94 739 750 10.1016/S0092-8674(00)81733-X 1:CAS:528: DyaK1cXmtlCjs7g%3D 9753321 (Pubitemid 28436006)
-
(1998)
Cell
, vol.94
, Issue.6
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.-Y.2
Yoshida, R.3
Elia, A.J.4
Hakem, A.5
Hakem, R.6
Penninger, J.M.7
Mak, T.W.8
-
45
-
-
0033539141
-
Interdigital cell death can occur through a necrotic and caspase-independent pathway
-
DOI 10.1016/S0960-9822(99)80425-4
-
M Chautan G Chazal F Cecconi P Gruss P Golstein 1999 Interdigital cell death can occur through a necrotic and caspase-independent pathway Curr Biol 9 967 970 10.1016/S0960-9822(99)80425-4 1:CAS:528:DyaK1MXlvFWlu7w%3D 10508592 (Pubitemid 29442482)
-
(1999)
Current Biology
, vol.9
, Issue.17
, pp. 967-970
-
-
Chautan, M.1
Chazal, G.2
Cecconi, F.3
Gruss, P.4
Golstein, P.5
-
46
-
-
54949152716
-
Caspase-independent cell death: Leaving the set without the final cut
-
10.1038/onc.2008.311 1:CAS:528:DC%2BD1cXht12ltLjM 18955972
-
SW Tait DR Green 2008 Caspase-independent cell death: leaving the set without the final cut Oncogene 27 6452 6461 10.1038/onc.2008.311 1:CAS:528:DC%2BD1cXht12ltLjM 18955972
-
(2008)
Oncogene
, vol.27
, pp. 6452-6461
-
-
Tait, S.W.1
Green, D.R.2
-
47
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
DOI 10.1038/35083620
-
LY Li X Luo X Wang 2001 Endonuclease G is an apoptotic DNase when released from mitochondria Nature 412 95 99 10.1038/35083620 1:CAS:528:DC%2BD3MXlt1Cqsr0%3D 11452314 (Pubitemid 32851517)
-
(2001)
Nature
, vol.412
, Issue.6842
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
48
-
-
9144244327
-
Endonuclease G is required for early embryogenesis and normal apoptosis in mice
-
DOI 10.1073/pnas.2636393100
-
J Zhang M Dong L Li Y Fan P Pathre J Dong D Lou JM Wells D Olivares-Villagomez L Van Kaer X Wang M Xu 2003 Endonuclease G is required for early embryogenesis and normal apoptosis in mice Proc Natl Acad Sci USA 100 15782 15787 10.1073/pnas.2636393100 1:CAS:528:DC%2BD2cXhtVCmtg%3D%3D 14663139 (Pubitemid 38021067)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.26
, pp. 15782-15787
-
-
Zhang, J.1
Dong, M.2
Li, L.3
Fan, Y.4
Pathre, P.5
Dong, J.6
Lou, D.7
Wells, J.M.8
Olivares-Villagomez, D.9
Van Kaer, L.10
Wang, X.11
Xu, M.12
-
49
-
-
33745250108
-
EndoG is dispensable in embryogenesis and apoptosis
-
10.1038/sj.cdd.4401787 1:CAS:528:DC%2BD28Xls1KhsLY%3D 16239930
-
KK David M Sasaki SW Yu TM Dawson VL Dawson 2006 EndoG is dispensable in embryogenesis and apoptosis Cell Death Differ 13 1147 1155 10.1038/sj.cdd. 4401787 1:CAS:528:DC%2BD28Xls1KhsLY%3D 16239930
-
(2006)
Cell Death Differ
, vol.13
, pp. 1147-1155
-
-
David, K.K.1
Sasaki, M.2
Yu, S.W.3
Dawson, T.M.4
Dawson, V.L.5
-
50
-
-
11144334739
-
Generation and characterization of endonuclease G null mice
-
DOI 10.1128/MCB.25.1.294-302.2005
-
RA Irvine N Adachi DK Shibata GD Cassell K Yu ZE Karanjawala CL Hsieh MR Lieber 2005 Generation and characterization of endonuclease G null mice Mol Cell Biol 25 294 302 10.1128/MCB.25.1.294-302.2005 1:CAS:528:DC%2BD2MXis1Ghsw%3D%3D 15601850 (Pubitemid 40039819)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.1
, pp. 294-302
-
-
Irvine, R.A.1
Adachi, N.2
Shibata, D.K.3
Cassell, G.D.4
Yu, K.5
Karanjawala, Z.E.6
Hsieh, C.-L.7
Lieber, M.R.8
-
51
-
-
0029950290
-
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
-
DOI 10.1084/jem.184.4.1331
-
SA Susin N Zamzami M Castedo T Hirsch P Marchetti A Macho E Daugas M Geuskens G Kroemer 1996 Bcl-2 inhibits the mitochondrial release of an apoptogenic protease J Exp Med 184 1331 1341 10.1084/jem.184.4.1331 1:CAS:528:DyaK28XmtlKiu7Y%3D 8879205 (Pubitemid 26354689)
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.4
, pp. 1331-1341
-
-
Susin, S.A.1
Zamzami, N.2
Castedo, M.3
Hirsch, T.4
Marchetti, P.5
Macho, A.6
Daugas, E.7
Geuskens, M.8
Kroemer, G.9
-
52
-
-
34447529458
-
BUB1 mediation of caspase-independent mitotic death determines cell fate
-
DOI 10.1083/jcb.200702134
-
Y Niikura A Dixit R Scott G Perkins K Kitagawa 2007 BUB1 mediation of caspase-independent mitotic death determines cell fate J Cell Biol 178 283 296 10.1083/jcb.200702134 1:CAS:528:DC%2BD2sXnvFCksL4%3D 17620410 (Pubitemid 47076464)
-
(2007)
Journal of Cell Biology
, vol.178
, Issue.2
, pp. 283-296
-
-
Niikura, Y.1
Dixit, A.2
Scott, R.3
Perkins, G.4
Kitagawa, K.5
-
53
-
-
1542426641
-
AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis
-
DOI 10.1038/sj.onc.1207279
-
C Cande N Vahsen I Kouranti E Schmitt E Daugas C Spahr J Luban RT Kroemer F Giordanetto C Garrido JM Penninger G Kroemer 2004 AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis Oncogene 23 1514 1521 10.1038/sj.onc.1207279 1:CAS:528:DC%2BD2cXhsFOht7w%3D 14716299 (Pubitemid 38406513)
-
(2004)
Oncogene
, vol.23
, Issue.8
, pp. 1514-1521
-
-
Cande, C.1
Vahsen, N.2
Kouranti, I.3
Schmitt, E.4
Daugas, E.5
Spahr, C.6
Luban, J.7
Kroemer, R.T.8
Giordanetto, F.9
Garrido, C.10
Penninger, J.M.11
Kroemer, G.12
-
54
-
-
33745628783
-
Loss of Aif function causes cell death in the mouse embryo, but the temporal progression of patterning is normal
-
DOI 10.1073/pnas.0603950103
-
D Brown BD Yu N Joza P Benit J Meneses M Firpo P Rustin JM Penninger GR Martin 2006 Loss of Aif function causes cell death in the mouse embryo, but the temporal progression of patterning is normal Proc Natl Acad Sci USA 103 9918 9923 10.1073/pnas.0603950103 1:CAS:528:DC%2BD28XmvVajtLc%3D 16788063 (Pubitemid 43993598)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.26
, pp. 9918-9923
-
-
Brown, D.1
Yu, B.D.2
Joza, N.3
Benit, P.4
Meneses, J.5
Firpo, M.6
Rustin, P.7
Penninger, J.M.8
Martin, G.R.9
-
55
-
-
33748341710
-
Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis
-
DOI 10.1038/sj.emboj.7601276, PII 7601276
-
EC Cheung N Joza NA Steenaart KA McClellan M Neuspiel S McNamara JG MacLaurin P Rippstein DS Park GC Shore HM McBride JM Penninger RS Slack 2006 Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis EMBO J 25 4061 4073 10.1038/sj.emboj. 7601276 1:CAS:528:DC%2BD28XptFWisrY%3D 16917506 (Pubitemid 44338747)
-
(2006)
EMBO Journal
, vol.25
, Issue.17
, pp. 4061-4073
-
-
Cheung, E.C.C.1
Joza, N.2
Steenaart, N.A.E.3
McClellan, K.A.4
Neuspiel, M.5
McNamara, S.6
MacLaurin, J.G.7
Rippstein, P.8
Park, D.S.9
Shore, G.C.10
McBride, H.M.11
Penninger, J.M.12
Slack, R.S.13
-
56
-
-
39449115415
-
The mitochondrial serine protease HtrA2/Omi: An overview
-
DOI 10.1038/sj.cdd.4402291, PII 4402291
-
L Vande Walle M Lamkanfi P Vandenabeele 2008 The mitochondrial serine protease HtrA2/Omi: an overview Cell Death Differ 15 453 460 10.1038/sj.cdd.4402291 (Pubitemid 351267296)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.3
, pp. 453-460
-
-
Vande Walle, L.1
Lamkanfi, M.2
Vandenabeele, P.3
-
57
-
-
7644230386
-
Neuroprotective role of the reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice
-
DOI 10.1128/MCB.24.22.9848-9862.2004
-
LM Martins A Morrison K Klupsch V Fedele N Moisoi P Teismann A Abuin E Grau M Geppert GP Livi CL Creasy A Martin I Hargreaves SJ Heales H Okada S Brandner JB Schulz T Mak J Downward 2004 Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice Mol Cell Biol 24 9848 9862 10.1128/MCB.24.22.9848-9862.2004 1:CAS:528: DC%2BD2cXpslOntbo%3D 15509788 (Pubitemid 39458812)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.22
, pp. 9848-9862
-
-
Martins, L.M.1
Morrison, A.2
Klupsch, K.3
Fedele, V.4
Moisoi, N.5
Teismann, P.6
Abuin, A.7
Grau, E.8
Geppert, M.9
Livi, G.P.10
Creasy, C.L.11
Martin, A.12
Hargreaves, I.13
Heales, S.J.14
Okada, H.15
Brandner, S.16
Schulz, J.B.17
Mak, T.18
Downward, J.19
-
58
-
-
60849097548
-
Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response
-
10.1038/cdd.2008.166 1:CAS:528:DC%2BD1MXit1Wkurw%3D 19023330
-
N Moisoi K Klupsch V Fedele P East S Sharma A Renton H Plun-Favreau RE Edwards P Teismann MD Esposti AD Morrison NW Wood J Downward LM Martins 2009 Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response Cell Death Differ 16 449 464 10.1038/cdd.2008.166 1:CAS:528:DC%2BD1MXit1Wkurw%3D 19023330
-
(2009)
Cell Death Differ
, vol.16
, pp. 449-464
-
-
Moisoi, N.1
Klupsch, K.2
Fedele, V.3
East, P.4
Sharma, S.5
Renton, A.6
Plun-Favreau, H.7
Edwards, R.E.8
Teismann, P.9
Esposti, M.D.10
Morrison, A.D.11
Wood, N.W.12
Downward, J.13
Martins, L.M.14
-
59
-
-
40449124712
-
Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons
-
DOI 10.1038/nature06604, PII NATURE06604
-
JR Chao E Parganas K Boyd CY Hong JT Opferman JN Ihle 2008 Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons Nature 452 98 102 10.1038/nature06604 1:CAS:528:DC%2BD1cXivFynu7k%3D 18288109 (Pubitemid 351355088)
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 98-102
-
-
Chao, J.-R.1
Parganas, E.2
Boyd, K.3
Hong, C.Y.4
Opferman, J.T.5
Ihle, J.N.6
-
60
-
-
34249279169
-
GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation
-
DOI 10.1016/j.cell.2007.03.045, PII S0092867407005144
-
A Colell JE Ricci S Tait S Milasta U Maurer L Bouchier-Hayes P Fitzgerald A Guio-Carrion NJ Waterhouse CW Li B Mari P Barbry DD Newmeyer HM Beere DR Green 2007 GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation Cell 129 983 997 10.1016/j.cell.2007.03.045 1:CAS:528:DC%2BD2sXmsl2qsb8%3D 17540177 (Pubitemid 46813151)
-
(2007)
Cell
, vol.129
, Issue.5
, pp. 983-997
-
-
Colell, A.1
Ricci, J.-E.2
Tait, S.3
Milasta, S.4
Maurer, U.5
Bouchier-Hayes, L.6
Fitzgerald, P.7
Guio-Carrion, A.8
Waterhouse, N.J.9
Li, C.W.10
Mari, B.11
Barbry, P.12
Newmeyer, D.D.13
Beere, H.M.14
Green, D.R.15
-
61
-
-
70449712602
-
Novel roles for GAPDH in cell death and carcinogenesis
-
10.1038/cdd.2009.137 1:CAS:528:DC%2BD1MXhsVWlsrzF 19779498
-
A Colell DR Green JE Ricci 2009 Novel roles for GAPDH in cell death and carcinogenesis Cell Death Differ 16 1573 1581 10.1038/cdd.2009.137 1:CAS:528:DC%2BD1MXhsVWlsrzF 19779498
-
(2009)
Cell Death Differ
, vol.16
, pp. 1573-1581
-
-
Colell, A.1
Green, D.R.2
Ricci, J.E.3
-
62
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
DOI 10.1038/35051606
-
MS Soengas P Capodieci D Polsky J Mora M Esteller X Opitz-Araya R McCombie JG Herman WL Gerald YA Lazebnik C Cordon-Cardo SW Lowe 2001 Inactivation of the apoptosis effector Apaf-1 in malignant melanoma Nature 409 207 211 10.1038/35051606 1:CAS:528:DC%2BD3MXlvFSrsA%3D%3D 11196646 (Pubitemid 32144287)
-
(2001)
Nature
, vol.409
, Issue.6817
, pp. 207-211
-
-
Soengas, M.S.1
Capodieci, P.2
Polsky, D.3
Mora, J.4
Esteller, M.5
Opitz-Araya, X.6
McCombie, R.7
Herman, J.G.8
Gerald, W.L.9
Lazebnik, Y.A.10
Cordon-Cardo, C.11
Lowe, S.W.12
-
63
-
-
0035880232
-
Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells
-
10.1182/blood.V98.2.414 1:CAS:528:DC%2BD3MXlt1KrtL4%3D 11435311
-
L Jia SM Srinivasula FT Liu AC Newland T Fernandes-Alnemri ES Alnemri SM Kelsey 2001 Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells Blood 98 414 421 10.1182/blood.V98.2.414 1:CAS:528:DC%2BD3MXlt1KrtL4%3D 11435311
-
(2001)
Blood
, vol.98
, pp. 414-421
-
-
Jia, L.1
Srinivasula, S.M.2
Liu, F.T.3
Newland, A.C.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
Kelsey, S.M.7
-
64
-
-
33947261638
-
Lack of apoptotic protease activating factor-1 expression and resistance to hypoxia-induced apoptosis in cervical cancer
-
DOI 10.1158/1078-0432.CCR-06-2371
-
C Leo LC Horn C Rauscher B Hentschel CE Richter A Schutz CP Leo M Hockel 2007 Lack of apoptotic protease activating factor-1 expression and resistance to hypoxia-induced apoptosis in cervical cancer Clin Cancer Res 13 1149 1153 10.1158/1078-0432.CCR-06-2371 1:CAS:528:DC%2BD2sXhvF2hsLk%3D 17317823 (Pubitemid 46424054)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.4
, pp. 1149-1153
-
-
Leo, C.1
Horn, L.-C.2
Rauscher, C.3
Hentschel, B.4
Richter, C.E.5
Schutz, A.6
Leo, C.P.7
Hockel, M.8
-
65
-
-
33947693893
-
Loss of APAF-1 expression is associated with tumour progression and adverse prognosis in colorectal cancer
-
DOI 10.1016/j.ejca.2007.01.029, PII S0959804907000688
-
I Zlobec P Minoo K Baker D Haegert K Khetani L Tornillo L Terracciano JR Jass A Lugli 2007 Loss of APAF-1 expression is associated with tumour progression and adverse prognosis in colorectal cancer Eur J Cancer 43 1101 1107 10.1016/j.ejca.2007.01.029 1:CAS:528:DC%2BD2sXjslGnurg%3D 17350821 (Pubitemid 46486708)
-
(2007)
European Journal of Cancer
, vol.43
, Issue.6
, pp. 1101-1107
-
-
Zlobec, I.1
Minoo, P.2
Baker, K.3
Haegert, D.4
Khetani, K.5
Tornillo, L.6
Terracciano, L.7
Jass, J.R.8
Lugli, A.9
-
66
-
-
19944419093
-
XIAP expression correlates with monocytic differentiation in adult de novo AML: Impact on prognosis
-
DOI 10.1038/sj.thj.6200549
-
I Tamm S Richter F Scholz K Schmelz D Oltersdorf L Karawajew C Schoch T Haferlach WD Ludwig C Wuchter 2004 XIAP expression correlates with monocytic differentiation in adult de novo AML: impact on prognosis Hematol J 5 489 495 10.1038/sj.thj.6200549 1:CAS:528:DC%2BD2cXhtVagtrzP 15570290 (Pubitemid 40045282)
-
(2004)
Hematology Journal
, vol.5
, Issue.6
, pp. 489-495
-
-
Tamm, I.1
Richter, S.2
Scholz, F.3
Schmelz, K.4
Oltersdorf, D.5
Karawajew, L.6
Schoch, C.7
Haferlach, T.8
Ludwig, W.-D.9
Wuchter, C.10
-
67
-
-
34047149327
-
XIAP as a prognostic marker of early recurrence of nonmuscular invasive bladder cancer
-
1:CAS:528:DC%2BD2sXkvVKqsbY%3D
-
M Li T Song ZF Yin YQ Na 2007 XIAP as a prognostic marker of early recurrence of nonmuscular invasive bladder cancer Chin Med J (Engl) 120 469 473 1:CAS:528:DC%2BD2sXkvVKqsbY%3D
-
(2007)
Chin Med J (Engl)
, vol.120
, pp. 469-473
-
-
Li, M.1
Song, T.2
Yin, Z.F.3
Na, Y.Q.4
-
68
-
-
59149083885
-
P34SEI-1 inhibits apoptosis through the stabilization of the X-linked inhibitor of apoptosis protein: P34SEI-1 as a novel target for anti-breast cancer strategies
-
10.1158/0008-5472.CAN-08-1189 1:CAS:528:DC%2BD1MXhtFOksLw%3D 19176394
-
SW Hong CJ Kim WS Park JS Shin SD Lee SG Ko SI Jung IC Park SK An WK Lee WJ Lee DH Jin MS Lee 2009 p34SEI-1 inhibits apoptosis through the stabilization of the X-linked inhibitor of apoptosis protein: p34SEI-1 as a novel target for anti-breast cancer strategies Cancer Res 69 741 746 10.1158/0008-5472.CAN-08- 1189 1:CAS:528:DC%2BD1MXhtFOksLw%3D 19176394
-
(2009)
Cancer Res
, vol.69
, pp. 741-746
-
-
Hong, S.W.1
Kim, C.J.2
Park, W.S.3
Shin, J.S.4
Lee, S.D.5
Ko, S.G.6
Jung, S.I.7
Park, I.C.8
An, S.K.9
Lee, W.K.10
Lee, W.J.11
Jin, D.H.12
Lee, M.S.13
-
69
-
-
8644284094
-
Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release
-
DOI 10.1128/MCB.24.23.10289-10299.2004
-
PB Deming ZT Schafer JS Tashker MB Potts M Deshmukh S Kornbluth 2004 Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release Mol Cell Biol 24 10289 10299 10.1128/MCB.24.23.10289-10299. 2004 1:CAS:528:DC%2BD2cXhtVart7rL 15542838 (Pubitemid 39507867)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.23
, pp. 10289-10299
-
-
Deming, P.B.1
Schafer, Z.T.2
Tashker, J.S.3
Potts, M.B.4
Deshmukh, M.5
Kornbluth, S.6
-
70
-
-
50249168335
-
Inhibition of apoptosome formation by suppression of Hsp90beta phosphorylation in tyrosine kinase-induced leukemias
-
10.1128/MCB.00265-08 1:CAS:528:DC%2BD1cXhtVersLvF 18591256
-
M Kurokawa C Zhao T Reya S Kornbluth 2008 Inhibition of apoptosome formation by suppression of Hsp90beta phosphorylation in tyrosine kinase-induced leukemias Mol Cell Biol 28 5494 5506 10.1128/MCB.00265-08 1:CAS:528: DC%2BD1cXhtVersLvF 18591256
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5494-5506
-
-
Kurokawa, M.1
Zhao, C.2
Reya, T.3
Kornbluth, S.4
-
71
-
-
54049135563
-
The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias
-
10.1038/cdd.2008.107 1:CAS:528:DC%2BD1cXht1aru7zO 18617896
-
Y Kamitsuji J Kuroda S Kimura S Toyokuni K Watanabe E Ashihara H Tanaka Y Yui M Watanabe H Matsubara Y Mizushima Y Hiraumi E Kawata T Yoshikawa T Maekawa T Nakahata S Adachi 2008 The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias Cell Death Differ 15 1712 1722 10.1038/cdd.2008.107 1:CAS:528:DC%2BD1cXht1aru7zO 18617896
-
(2008)
Cell Death Differ
, vol.15
, pp. 1712-1722
-
-
Kamitsuji, Y.1
Kuroda, J.2
Kimura, S.3
Toyokuni, S.4
Watanabe, K.5
Ashihara, E.6
Tanaka, H.7
Yui, Y.8
Watanabe, M.9
Matsubara, H.10
Mizushima, Y.11
Hiraumi, Y.12
Kawata, E.13
Yoshikawa, T.14
Maekawa, T.15
Nakahata, T.16
Adachi, S.17
-
72
-
-
1542283719
-
A novel mechanism for imatinib mesylate-induced cell death of BCR-ABL-positive human leukemic cells: Caspase-independent, necrosis-like programmed cell death mediated by serine protease activity
-
DOI 10.1182/blood-2003-05-1605
-
M Okada S Adachi T Imai K Watanabe SY Toyokuni M Ueno AS Zervos G Kroemer T Nakahata 2004 A novel mechanism for imatinib mesylate-induced cell death of BCR-ABL-positive human leukemic cells: caspase-independent, necrosis-like programmed cell death mediated by serine protease activity Blood 103 2299 2307 10.1182/blood-2003-05-1605 1:CAS:528:DC%2BD2cXitlCjsrg%3D 14645012 (Pubitemid 38326250)
-
(2004)
Blood
, vol.103
, Issue.6
, pp. 2299-2307
-
-
Okada, M.1
Adachi, S.2
Imai, T.3
Watanabe, K.-I.4
Toyokuni, S.-Y.5
Ueno, M.6
Zervos, A.S.7
Kroemer, G.8
Nakahata, T.9
-
73
-
-
35448967331
-
Part I: Mechanisms of resistance to imatinib in chronic myeloid leukaemia
-
DOI 10.1016/S1470-2045(07)70342-X, PII S147020450770342X
-
JF Apperley 2007 Part I: mechanisms of resistance to imatinib in chronic myeloid leukaemia Lancet Oncol 8 1018 1029 10.1016/S1470-2045(07)70342-X 1:CAS:528:DC%2BD2sXht1GrsbjL 17976612 (Pubitemid 47629897)
-
(2007)
Lancet Oncology
, vol.8
, Issue.11
, pp. 1018-1029
-
-
Apperley, J.F.1
-
74
-
-
66149148740
-
Modulation of caspase-independent cell death leads to resensitization of imatinib mesylate-resistant cells
-
10.1158/0008-5472.CAN-08-2731 1:CAS:528:DC%2BD1MXjvVWisbo%3D 19318579
-
VJ Lavallard LA Pradelli A Paul M Beneteau A Jacquel P Auberger JE Ricci 2009 Modulation of caspase-independent cell death leads to resensitization of imatinib mesylate-resistant cells Cancer Res 69 3013 3020 10.1158/0008-5472.CAN- 08-2731 1:CAS:528:DC%2BD1MXjvVWisbo%3D 19318579
-
(2009)
Cancer Res
, vol.69
, pp. 3013-3020
-
-
Lavallard, V.J.1
Pradelli, L.A.2
Paul, A.3
Beneteau, M.4
Jacquel, A.5
Auberger, P.6
Ricci, J.E.7
-
75
-
-
61849134364
-
Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells
-
10.1182/blood-2008-05-157842 1:CAS:528:DC%2BD1MXivVaqtr0%3D 18978206
-
E Hulleman KM Kazemier A Holleman DJ VanderWeele CM Rudin MJ Broekhuis WE Evans R Pieters ML Den Boer 2009 Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells Blood 113 2014 2021 10.1182/blood-2008-05-157842 1:CAS:528:DC%2BD1MXivVaqtr0%3D 18978206
-
(2009)
Blood
, vol.113
, pp. 2014-2021
-
-
Hulleman, E.1
Kazemier, K.M.2
Holleman, A.3
Vanderweele, D.J.4
Rudin, C.M.5
Broekhuis, M.J.6
Evans, W.E.7
Pieters, R.8
Den Boer, M.L.9
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