Alpha-lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway

FEBS Letters

Volumn 582, Issue 12, 2008, Pages 1667-1671

  Shi, Dong yun ^a,b   Liu, Hong lei ^b   Stern, Jeremy S ^c   Yu, Pei zhong ^a   Liu, Shan lin ^a  

^a FUDAN UNIVERSITY   (China)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c ST GEORGE S HOSPITAL   (United Kingdom)

Author keywords

Lipoic acid ( LA); Akt (PKB); Apoptosis; Caspase; PTEN; Reactive oxygen species (ROS)

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TENSIN; THIOCTIC ACID;

APOPTOSIS; ARTICLE; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE DELETION; HEPATOMA CELL; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; SCAVENGING SYSTEM;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CASPASES; CELL LINE, TUMOR; ENZYME ACTIVATION; FREE RADICAL SCAVENGERS; HUMANS; LIVER NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; REACTIVE OXYGEN SPECIES; THIOCTIC ACID;

EID: 43549122067     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.04.021     Document Type: Article

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