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Volumn 27, Issue 34, 2009, Pages
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LKB1 and mammalian target of rapamycin as predictive factors for the anticancer efficacy of metformin
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Author keywords
[No Author keywords available]
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Indexed keywords
HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;
INSULIN;
MAMMALIAN TARGET OF RAPAMYCIN;
METFORMIN;
PROTEIN KINASE C ZETA;
PROTEIN KINASE LKB1;
REACTIVE NITROGEN SPECIES;
SOMATOMEDIN C;
AMP ACTIVATED PROTEIN KINASE KINASE;
AMP-ACTIVATED PROTEIN KINASE KINASE;
PROTEIN KINASE;
PROTEIN SERINE THREONINE KINASE;
STK11 PROTEIN, HUMAN;
ADENOCARCINOMA;
ANTINEOPLASTIC ACTIVITY;
BREAST CANCER;
CALORIC RESTRICTION;
CANCER ADJUVANT THERAPY;
CANCER CELL CULTURE;
CANCER GROWTH;
CANCER SURGERY;
CARCINOGENESIS;
CELL ACTIVATION;
CELL NUCLEUS;
CELL PROLIFERATION;
CLINICAL TRIAL;
CYTOPLASM;
DIABETES MELLITUS;
DRUG EFFICACY;
ENZYME ACTIVATION;
ENZYME PHOSPHORYLATION;
EPIGENETICS;
GENE MUTATION;
GENE SILENCING;
HAMARTOMA;
HUMAN;
IN VITRO STUDY;
IN VIVO STUDY;
INSULIN BLOOD LEVEL;
INTRACELLULAR SPACE;
LETTER;
LOSS OF FUNCTION MUTATION;
LUNG NON SMALL CELL CANCER;
PEUTZ JEGHERS SYNDROME;
PREDICTION;
PRIMARY TUMOR;
PRIORITY JOURNAL;
PROGNOSIS;
PROTEIN EXPRESSION;
PROTEIN LOCALIZATION;
PROTEIN SYNTHESIS;
RNA TRANSLATION;
SIGNAL TRANSDUCTION;
SOMATIC MUTATION;
TREATMENT RESPONSE;
ADJUVANT THERAPY;
BREAST TUMOR;
FEMALE;
METABOLISM;
NOTE;
BREAST NEOPLASMS;
FEMALE;
HUMANS;
METFORMIN;
NEOADJUVANT THERAPY;
PROTEIN KINASES;
PROTEIN-SERINE-THREONINE KINASES;
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EID: 73349087844
PISSN: 0732183X
EISSN: None
Source Type: Journal
DOI: 10.1200/JCO.2009.25.3963 Document Type: Letter |
Times cited : (45)
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References (9)
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