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Volumn 27, Issue 34, 2009, Pages

LKB1 and mammalian target of rapamycin as predictive factors for the anticancer efficacy of metformin

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; METFORMIN; PROTEIN KINASE C ZETA; PROTEIN KINASE LKB1; REACTIVE NITROGEN SPECIES; SOMATOMEDIN C; AMP ACTIVATED PROTEIN KINASE KINASE; AMP-ACTIVATED PROTEIN KINASE KINASE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; STK11 PROTEIN, HUMAN;

EID: 73349087844     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2009.25.3963     Document Type: Letter
Times cited : (45)

References (9)
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    • Xie Z, Dong Y, Scholz R, et al: Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells. Circulation 117:952-962, 2008
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    • Esteller, M.1    Avizienyte, E.2    Corn, P.G.3
  • 7
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    • The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma
    • Shen Z, Wen XF, Lan F, et al: The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinoma. Clin Cancer Res 8:2085-2090, 2002
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    • Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.