메뉴 건너뛰기




Volumn 50, Issue 2, 2011, Pages 193-211

Is lipid signaling through cannabinoid 2 receptors part of a protective system?

Author keywords

Cannabinoid 1 and 2 receptors; Disease; Endocannabinoids; Immune function; Inflammation

Indexed keywords

1 (2,3 DICHLOROBENZOYL) 5 METHOXY 2 METHYL 3 (2 MORPHOLINOETHYL)INDOLE; 1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 [4 (1,1 DIMETHYLHEPTYL) 2,6 DIMETHOXYPHENYL] 6,6 DIMETHYLBICYCLO[3.1.1]HEPT 2 EN 2 YLMETHANOL; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; CANNABINOID 2 RECEPTOR; DESIPRAMINE; DEXANABINOL; ENDOCANNABINOID; LIPID;

EID: 79952198989     PISSN: 01637827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plipres.2011.01.001     Document Type: Review
Times cited : (361)

References (286)
  • 1
    • 54749112350 scopus 로고    scopus 로고
    • Modulation of the endocannabinoid system in cardiovascular disease: Therapeutic potential and limitations
    • P. Pacher, P. Mukhopadhyay, R. Mohanraj, G. Godlewski, S. Batkai, and G. Kunos Modulation of the endocannabinoid system in cardiovascular disease: therapeutic potential and limitations Hypertension 52 2008 601 607
    • (2008) Hypertension , vol.52 , pp. 601-607
    • Pacher, P.1    Mukhopadhyay, P.2    Mohanraj, R.3    Godlewski, G.4    Batkai, S.5    Kunos, G.6
  • 2
    • 67749086243 scopus 로고    scopus 로고
    • The emerging role of the endocannabinoid system in cardiovascular disease
    • P. Pacher, and S. Steffens The emerging role of the endocannabinoid system in cardiovascular disease Semin Immunopathol 31 2009 63 77
    • (2009) Semin Immunopathol , vol.31 , pp. 63-77
    • Pacher, P.1    Steffens, S.2
  • 3
    • 67449135862 scopus 로고    scopus 로고
    • Cannabinoids in intestinal inflammation and cancer
    • A.A. Izzo, and M. Camilleri Cannabinoids in intestinal inflammation and cancer Pharmacol Res 60 2009 117 125
    • (2009) Pharmacol Res , vol.60 , pp. 117-125
    • Izzo, A.A.1    Camilleri, M.2
  • 4
    • 77649275461 scopus 로고    scopus 로고
    • Cannabinoids and the gut: New developments and emerging concepts
    • A.A. Izzo, and K.A. Sharkey Cannabinoids and the gut: new developments and emerging concepts Pharmacol Ther 126 2010 21 38
    • (2010) Pharmacol Ther , vol.126 , pp. 21-38
    • Izzo, A.A.1    Sharkey, K.A.2
  • 5
    • 38349181757 scopus 로고    scopus 로고
    • Endocannabinoids and liver disease. I. Endocannabinoids and their receptors in the liver
    • A. Mallat, and S. Lotersztajn Endocannabinoids and liver disease. I. Endocannabinoids and their receptors in the liver Am J Physiol Gastrointest Liver Physiol 294 2008 G9 G12
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Mallat, A.1    Lotersztajn, S.2
  • 7
    • 42049111404 scopus 로고    scopus 로고
    • Endocannabinoids and liver disease. III. Endocannabinoid effects on immune cells: Implications for inflammatory liver diseases
    • P. Pacher, and B. Gao Endocannabinoids and liver disease. III. Endocannabinoid effects on immune cells: implications for inflammatory liver diseases Am J Physiol Gastrointest Liver Physiol 294 2008 G850 G854
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Pacher, P.1    Gao, B.2
  • 8
    • 73449112234 scopus 로고    scopus 로고
    • Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy
    • P. Mukhopadhyay, M. Rajesh, H. Pan, V. Patel, B. Mukhopadhyay, and S. Batkai Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy Free Radic Biol Med 48 2010 457 467
    • (2010) Free Radic Biol Med , vol.48 , pp. 457-467
    • Mukhopadhyay, P.1    Rajesh, M.2    Pan, H.3    Patel, V.4    Mukhopadhyay, B.5    Batkai, S.6
  • 10
    • 33748703859 scopus 로고    scopus 로고
    • The endocannabinoid system as an emerging target of pharmacotherapy
    • DOI 10.1124/pr.58.3.2
    • P. Pacher, S. Batkai, and G. Kunos The endocannabinoid system as an emerging target of pharmacotherapy Pharmacol Rev 58 2006 389 462 (Pubitemid 44394908)
    • (2006) Pharmacological Reviews , vol.58 , Issue.3 , pp. 389-462
    • Pacher, P.1    Batkai, S.2    Kunos, G.3
  • 11
    • 33947591537 scopus 로고    scopus 로고
    • The endocannabinoid system in targeting inflammatory neurodegenerative diseases
    • DOI 10.1016/j.tips.2007.02.004, PII S016561470700048X
    • D. Centonze, A. Finazzi-Agro, G. Bernardi, and M. Maccarrone The endocannabinoid system in targeting inflammatory neurodegenerative diseases Trends Pharmacol Sci 28 2007 180 187 (Pubitemid 46483718)
    • (2007) Trends in Pharmacological Sciences , vol.28 , Issue.4 , pp. 180-187
    • Centonze, D.1    Finazzi-Agro, A.2    Bernardi, G.3    Maccarrone, M.4
  • 14
    • 67649843735 scopus 로고    scopus 로고
    • The endocannabinoid system as a target for the treatment of motor dysfunction
    • J. Fernandez-Ruiz The endocannabinoid system as a target for the treatment of motor dysfunction Br J Pharmacol 156 2009 1029 1040
    • (2009) Br J Pharmacol , vol.156 , pp. 1029-1040
    • Fernandez-Ruiz, J.1
  • 16
    • 79952769113 scopus 로고    scopus 로고
    • 2 receptor antagonist, AM630, on isolation rearing - Induced behavioural deficits in rats
    • 2 receptor antagonist, AM630, on isolation rearing - induced behavioural deficits in rats Schizophr Res 117 2010 391 392
    • (2010) Schizophr Res , vol.117 , pp. 391-392
    • Khan, A.1    Kendall, D.A.2    Fone, K.C.F.3
  • 20
    • 78650595351 scopus 로고    scopus 로고
    • 2 cannabinoid receptors decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice
    • 2 cannabinoid receptors decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice J Psychopharmacol 25 1 2011 111 120
    • (2011) J Psychopharmacol , vol.25 , Issue.1 , pp. 111-120
    • Garcia-Gutierrez, M.S.1    Manzanares, J.2
  • 22
    • 38349119715 scopus 로고    scopus 로고
    • 2 receptors: A therapeutic target for the treatment of inflammatory and neuropathic pain
    • 2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain Br J Pharmacol 153 2008 319 334
    • (2008) Br J Pharmacol , vol.153 , pp. 319-334
    • Guindon, J.1    Hohmann, A.G.2
  • 23
    • 0142166330 scopus 로고    scopus 로고
    • Cannabinoids: Potential anticancer agents
    • M. Guzman Cannabinoids: potential anticancer agents Nat Rev Cancer 3 2003 745 755 (Pubitemid 37328813)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.10 , pp. 745-755
    • Guzman, M.1
  • 24
    • 67449138588 scopus 로고    scopus 로고
    • Endocannabinoid system modulation in cancer biology and therapy
    • S. Pisanti, and M. Bifulco Endocannabinoid system modulation in cancer biology and therapy Pharmacol Res 60 2009 107 116
    • (2009) Pharmacol Res , vol.60 , pp. 107-116
    • Pisanti, S.1    Bifulco, M.2
  • 25
    • 77954406421 scopus 로고    scopus 로고
    • Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas
    • N. Stella Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas Glia 58 2010 1017 1030
    • (2010) Glia , vol.58 , pp. 1017-1030
    • Stella, N.1
  • 27
    • 38349132542 scopus 로고    scopus 로고
    • Cannabinoid receptors and the regulation of bone mass
    • I. Bab, and A. Zimmer Cannabinoid receptors and the regulation of bone mass Br J Pharmacol 153 2008 182 188
    • (2008) Br J Pharmacol , vol.153 , pp. 182-188
    • Bab, I.1    Zimmer, A.2
  • 28
    • 72949117074 scopus 로고    scopus 로고
    • Cannabinoids and the skeleton: From marijuana to reversal of bone loss
    • I. Bab, A. Zimmer, and E. Melamed Cannabinoids and the skeleton: from marijuana to reversal of bone loss Ann Med 41 2009 560 567
    • (2009) Ann Med , vol.41 , pp. 560-567
    • Bab, I.1    Zimmer, A.2    Melamed, E.3
  • 29
    • 38349184209 scopus 로고    scopus 로고
    • 2 receptors in reproduction
    • 2 receptors in reproduction Br J Pharmacol 153 2008 189 198
    • (2008) Br J Pharmacol , vol.153 , pp. 189-198
    • MacCarrone, M.1
  • 30
    • 70350072546 scopus 로고    scopus 로고
    • Endocannabinoids: Friends and foes of reproduction
    • M. Maccarrone Endocannabinoids: friends and foes of reproduction Prog Lipid Res 48 2009 344 354
    • (2009) Prog Lipid Res , vol.48 , pp. 344-354
    • MacCarrone, M.1
  • 32
    • 67849092895 scopus 로고    scopus 로고
    • The endocannabinoid system of the skin in health and disease: Novel perspectives and therapeutic opportunities
    • T. Biro, B.I. Toth, G. Hasko, R. Paus, and P. Pacher The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities Trends Pharmacol Sci 30 2009 411 420
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 411-420
    • Biro, T.1    Toth, B.I.2    Hasko, G.3    Paus, R.4    Pacher, P.5
  • 33
    • 0033660254 scopus 로고    scopus 로고
    • A historical overview of chemical research on cannabinoids
    • R. Mechoulam, and L. Hanus A historical overview of chemical research on cannabinoids Chem Phys Lipids 108 2000 1 13
    • (2000) Chem Phys Lipids , vol.108 , pp. 1-13
    • Mechoulam, R.1    Hanus, L.2
  • 34
    • 33947489961 scopus 로고
    • Isolation, structure and partial synthesis of an active constituent of hashish
    • Y. Gaoni, and R. Mechoulam Isolation, structure and partial synthesis of an active constituent of hashish J Am Chem Soc 86 1964 1646 1647
    • (1964) J Am Chem Soc , vol.86 , pp. 1646-1647
    • Gaoni, Y.1    Mechoulam, R.2
  • 35
    • 0001471504 scopus 로고
    • The physiological mode of action of tetrahydrocannabinol on cell membranes
    • E.W. Gill, and D.K. Lawrence The physiological mode of action of tetrahydrocannabinol on cell membranes Pharmacol Marihuana 1 1976 147 155
    • (1976) Pharmacol Marihuana , vol.1 , pp. 147-155
    • Gill, E.W.1    Lawrence, D.K.2
  • 38
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • L.A. Matsuda, S.J. Lolait, M.J. Brownstein, A.C. Young, and T.I. Bonner Structure of a cannabinoid receptor and functional expression of the cloned cDNA Nature 346 1990 561 564
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 39
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • DOI 10.1038/365061a0
    • S. Munro, K.L. Thomas, and M. Abu-Shaar Molecular characterization of a peripheral receptor for cannabinoids Nature 365 1993 61 65 (Pubitemid 23305569)
    • (1993) Nature , vol.365 , Issue.6441 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 41
    • 4544275181 scopus 로고    scopus 로고
    • The endocannabinoid system and its therapeutic exploitation
    • DOI 10.1038/nrd1495
    • V. Di Marzo, M. Bifulco, and L. De Petrocellis The endocannabinoid system and its therapeutic exploitation Nat Rev Drug Discov 3 2004 771 784 (Pubitemid 39242829)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.9 , pp. 771-784
    • Di Marzo, V.1    Bifulco, M.2    De Petrocellis, L.3
  • 43
    • 79953006067 scopus 로고    scopus 로고
    • Pharmacology of GPR55 in yeast and identification of GSK494581A as a mixed-activity GlyT1 inhibitor and GPR55 agonist
    • in press
    • Brown AJ, Daniels DA, Kassim M, Brown S, Haslam CP, Terrell VR, et al. Pharmacology of GPR55 in yeast and identification of GSK494581A as a mixed-activity GlyT1 inhibitor and GPR55 agonist. J Pharmacol Exp Ther, in press. doi:10.1124/jpet.110.172650.
    • J Pharmacol Exp Ther
    • Brown, A.J.1    Daniels, D.A.2    Kassim, M.3    Brown, S.4    Haslam, C.P.5    Terrell, V.R.6
  • 44
    • 0032970173 scopus 로고    scopus 로고
    • Vanilloid (Capsaicin) receptors and mechanisms
    • A. Szallasi, and P.M. Blumberg Vanilloid (Capsaicin) receptors and mechanisms Pharmacol Rev 51 1999 159 212
    • (1999) Pharmacol Rev , vol.51 , pp. 159-212
    • Szallasi, A.1    Blumberg, P.M.2
  • 45
    • 77950660113 scopus 로고    scopus 로고
    • Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs
    • V. Di Marzo, and L. De Petrocellis Endocannabinoids as regulators of transient receptor potential (TRP) channels: a further opportunity to develop new endocannabinoid-based therapeutic drugs Curr Med Chem 17 2010 1430 1449
    • (2010) Curr Med Chem , vol.17 , pp. 1430-1449
    • Di Marzo, V.1    De Petrocellis, L.2
  • 46
    • 78649369301 scopus 로고    scopus 로고
    • Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens
    • B.A. Grueter, G. Brasnjo, and R.C. Malenka Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens Nat Neurosci 13 2010 1519 1525
    • (2010) Nat Neurosci , vol.13 , pp. 1519-1525
    • Grueter, B.A.1    Brasnjo, G.2    Malenka, R.C.3
  • 47
    • 78649374688 scopus 로고    scopus 로고
    • TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus
    • A.E. Chavez, C.Q. Chiu, and P.E. Castillo TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus Nat Neurosci 13 2010 1511 1518
    • (2010) Nat Neurosci , vol.13 , pp. 1511-1518
    • Chavez, A.E.1    Chiu, C.Q.2    Castillo, P.E.3
  • 48
    • 78649387224 scopus 로고    scopus 로고
    • Anandamide serves two masters in the brain
    • V. Di Marzo Anandamide serves two masters in the brain Nat Neurosci 13 2010 1446 1448
    • (2010) Nat Neurosci , vol.13 , pp. 1446-1448
    • Di Marzo, V.1
  • 50
    • 77952623444 scopus 로고    scopus 로고
    • 2: A cannabinoid receptor with an identity crisis
    • 2: a cannabinoid receptor with an identity crisis Br J Pharmacol 160 2010 467 479
    • (2010) Br J Pharmacol , vol.160 , pp. 467-479
    • Atwood, B.K.1    MacKie, K.2
  • 52
    • 72149116426 scopus 로고    scopus 로고
    • Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling
    • C. Borner, M. Smida, V. Hollt, B. Schraven, and J. Kraus Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling J Biol Chem 284 2009 35450 35460
    • (2009) J Biol Chem , vol.284 , pp. 35450-35460
    • Borner, C.1    Smida, M.2    Hollt, V.3    Schraven, B.4    Kraus, J.5
  • 55
    • 0029012014 scopus 로고
    • Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
    • R. Mechoulam, S. Ben-Shabat, L. Hanus, M. Ligumsky, N.E. Kaminski, and A.R. Schatz Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors Biochem Pharmacol 50 1995 83 90
    • (1995) Biochem Pharmacol , vol.50 , pp. 83-90
    • Mechoulam, R.1    Ben-Shabat, S.2    Hanus, L.3    Ligumsky, M.4    Kaminski, N.E.5    Schatz, A.R.6
  • 57
    • 0242268553 scopus 로고    scopus 로고
    • The molecular logic of endocannabinoid signalling
    • DOI 10.1038/nrn1247
    • D. Piomelli The molecular logic of endocannabinoid signalling Nat Rev Neurosci 4 2003 873 884 (Pubitemid 37351427)
    • (2003) Nature Reviews Neuroscience , vol.4 , Issue.11 , pp. 873-884
    • Piomelli, D.1
  • 58
    • 77950633627 scopus 로고    scopus 로고
    • Novel natural and synthetic ligands of the endocannabinoid system
    • L.O. Hanus, and R. Mechoulam Novel natural and synthetic ligands of the endocannabinoid system Curr Med Chem 17 2010 1341 1359
    • (2010) Curr Med Chem , vol.17 , pp. 1341-1359
    • Hanus, L.O.1    Mechoulam, R.2
  • 59
    • 69549128249 scopus 로고    scopus 로고
    • Biology of endocannabinoid synthesis system
    • J. Wang, and N. Ueda Biology of endocannabinoid synthesis system Prostaglandins Other Lipid Mediat 89 2009 112 119
    • (2009) Prostaglandins Other Lipid Mediat , vol.89 , pp. 112-119
    • Wang, J.1    Ueda, N.2
  • 60
    • 0037207093 scopus 로고    scopus 로고
    • The enzymatic inactivation of the fatty acid amide class of signaling lipids
    • DOI 10.1016/S0009-3084(02)00147-0, PII S0009308402001470
    • B.F. Cravatt, and A.H. Lichtman The enzymatic inactivation of the fatty acid amide class of signaling lipids Chem Phys Lipids 121 2002 135 148 (Pubitemid 36044548)
    • (2002) Chemistry and Physics of Lipids , vol.121 , Issue.1-2 , pp. 135-148
    • Cravatt, B.F.1    Lichtman, A.H.2
  • 61
    • 22244484464 scopus 로고    scopus 로고
    • Structure and function of fatty acid amide hydrolase
    • DOI 10.1146/annurev.biochem.74.082803.133450
    • M.K. McKinney, and B.F. Cravatt Structure and function of fatty acid amide hydrolase Annu Rev Biochem 74 2005 411 432 (Pubitemid 40995513)
    • (2005) Annual Review of Biochemistry , vol.74 , pp. 411-432
    • McKinney, M.K.1    Cravatt, B.E.2
  • 62
    • 58149296562 scopus 로고    scopus 로고
    • Fatty acid amide hydrolase: A gate-keeper of the endocannabinoid system
    • F. Fezza, C. De Simone, D. Amadio, and M. Maccarrone Fatty acid amide hydrolase: a gate-keeper of the endocannabinoid system Subcell Biochem 49 2008 101 132
    • (2008) Subcell Biochem , vol.49 , pp. 101-132
    • Fezza, F.1    De Simone, C.2    Amadio, D.3    MacCarrone, M.4
  • 63
    • 43249100162 scopus 로고    scopus 로고
    • Targeting the endocannabinoid system: To enhance or reduce?
    • DOI 10.1038/nrd2553, PII NRD2553
    • V. Di Marzo Targeting the endocannabinoid system: to enhance or reduce? Nat Rev Drug Discov 7 2008 438 455 (Pubitemid 351649182)
    • (2008) Nature Reviews Drug Discovery , vol.7 , Issue.5 , pp. 438-455
    • Di Marzo, V.1
  • 64
    • 79151478285 scopus 로고    scopus 로고
    • Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2
    • S. Brogi, F. Corelli, V. Di Marzo, A. Ligresti, C. Mugnaini, and S. Pasquini Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2 Eur J Med Chem 46 2 2011 547 555
    • (2011) Eur J Med Chem , vol.46 , Issue.2 , pp. 547-555
    • Brogi, S.1    Corelli, F.2    Di Marzo, V.3    Ligresti, A.4    Mugnaini, C.5    Pasquini, S.6
  • 69
    • 78049285545 scopus 로고    scopus 로고
    • 2 receptor-specific inverse agonists
    • 2 receptor-specific inverse agonists Curr Top Med Chem 10 2010 768 778
    • (2010) Curr Top Med Chem , vol.10 , pp. 768-778
    • Lunn, C.A.1
  • 70
    • 84884474728 scopus 로고    scopus 로고
    • Pharmacological actions of cannabinoids
    • R.G. Pertwee Pharmacological actions of cannabinoids Handb Exp Pharmacol 2005 1 51
    • (2005) Handb Exp Pharmacol , pp. 1-51
    • Pertwee, R.G.1
  • 73
    • 34250717998 scopus 로고    scopus 로고
    • 2 receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model
    • DOI 10.1038/sj.jcbfm.9600447, PII 9600447
    • M. Zhang, B.R. Martin, M.W. Adler, R.K. Razdan, J.I. Jallo, and R.F. Tuma Cannabinoid CB(2) receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model J Cereb Blood Flow Metab 27 2007 1387 1396 (Pubitemid 46985356)
    • (2007) Journal of Cerebral Blood Flow and Metabolism , vol.27 , Issue.7 , pp. 1387-1396
    • Zhang, M.1    Martin, B.R.2    Adler, M.W.3    Razdan, R.K.4    Jallo, J.I.5    Tuma, R.F.6
  • 77
    • 18844400058 scopus 로고    scopus 로고
    • Cannabinoid-based drugs as anti-inflammatory therapeutics
    • DOI 10.1038/nri1602
    • T.W. Klein Cannabinoid-based drugs as anti-inflammatory therapeutics Nat Rev Immunol 5 2005 400 411 (Pubitemid 40685989)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.5 , pp. 400-411
    • Klein, T.W.1
  • 78
    • 33947128224 scopus 로고    scopus 로고
    • Endocannabinoids and the regulation of their levels in health and disease
    • DOI 10.1097/MOL.0b013e32803dbdec, PII 0004143320070400000003
    • V. Di Marzo, and S. Petrosino Endocannabinoids and the regulation of their levels in health and disease Curr Opin Lipidol 18 2007 129 140 (Pubitemid 46412082)
    • (2007) Current Opinion in Lipidology , vol.18 , Issue.2 , pp. 129-140
    • Di Marzo, V.1    Petrosino, S.2
  • 81
    • 38349086382 scopus 로고    scopus 로고
    • 2 receptor-mediated migration of immune cells: It can go either way
    • 2 receptor-mediated migration of immune cells: it can go either way Br J Pharmacol 153 2008 299 308
    • (2008) Br J Pharmacol , vol.153 , pp. 299-308
    • Miller, A.M.1    Stella, N.2
  • 82
    • 38349099590 scopus 로고    scopus 로고
    • The peripheral cannabinoid receptor knockout mice: An update
    • N.E. Buckley The peripheral cannabinoid receptor knockout mice: an update Br J Pharmacol 153 2008 309 318
    • (2008) Br J Pharmacol , vol.153 , pp. 309-318
    • Buckley, N.E.1
  • 83
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • DOI 10.1152/physrev.00029.2006
    • P. Pacher, J.S. Beckman, and L. Liaudet Nitric oxide and peroxynitrite in health and disease Physiol Rev 87 2007 315 424 (Pubitemid 46217686)
    • (2007) Physiological Reviews , vol.87 , Issue.1 , pp. 315-424
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 84
    • 78751683133 scopus 로고    scopus 로고
    • Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization
    • S. Jiang, M. Alberich-Jorda, R. Zagozdzon, K. Parmar, Y. Fu, and P. Mauch Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization Blood 117 2011 827 838
    • (2011) Blood , vol.117 , pp. 827-838
    • Jiang, S.1    Alberich-Jorda, M.2    Zagozdzon, R.3    Parmar, K.4    Fu, Y.5    Mauch, P.6
  • 85
    • 34147173269 scopus 로고    scopus 로고
    • 2 receptors in the brain
    • 2 receptors in the brain Neuropsychobiology 54 2006 231 246
    • (2006) Neuropsychobiology , vol.54 , pp. 231-246
    • Onaivi, E.S.1
  • 86
    • 62749123023 scopus 로고    scopus 로고
    • Cannabinoid type 2 receptor as a target for chronic - Pain
    • M. Beltramo Cannabinoid type 2 receptor as a target for chronic - pain Mini Rev Med Chem 9 2009 11 25
    • (2009) Mini Rev Med Chem , vol.9 , pp. 11-25
    • Beltramo, M.1
  • 87
    • 38349119136 scopus 로고    scopus 로고
    • 2 receptors in the gastrointestinal tract: A regulatory system in states of inflammation
    • 2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation Br J Pharmacol 153 2008 263 270
    • (2008) Br J Pharmacol , vol.153 , pp. 263-270
    • Wright, K.L.1    Duncan, M.2    Sharkey, K.A.3
  • 88
    • 70149125201 scopus 로고    scopus 로고
    • Ulcerative colitis induces changes on the expression of the endocannabinoid system in the human colonic tissue
    • L. Marquez, J. Suarez, M. Iglesias, F.J. Bermudez-Silva, F. Rodriguez de Fonseca, and M. Andreu Ulcerative colitis induces changes on the expression of the endocannabinoid system in the human colonic tissue PLoS One 4 2009 e6893
    • (2009) PLoS One , vol.4 , pp. 6893
    • Marquez, L.1    Suarez, J.2    Iglesias, M.3    Bermudez-Silva, F.J.4    Rodriguez De Fonseca, F.5    Andreu, M.6
  • 91
    • 42349086864 scopus 로고    scopus 로고
    • Endocannabinoids and the regulation of bone metabolism
    • DOI 10.1111/j.1365-2826.2008.01675.x
    • I. Bab, O. Ofek, J. Tam, J. Rehnelt, and A. Zimmer Endocannabinoids and the regulation of bone metabolism J Neuroendocrinol 20 Suppl. 1 2008 69 74 (Pubitemid 351552679)
    • (2008) Journal of Neuroendocrinology , vol.20 , Issue.SUPPL. 1 , pp. 69-74
    • Bab, I.1    Ofek, O.2    Tam, J.3    Rehnelt, J.4    Zimmer, A.5
  • 93
    • 76749118468 scopus 로고    scopus 로고
    • 1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes
    • 1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes Cardiovasc Res 85 2010 773 784
    • (2010) Cardiovasc Res , vol.85 , pp. 773-784
    • Mukhopadhyay, P.1    Rajesh, M.2    Batkai, S.3    Patel, V.4    Kashiwaya, Y.5    Liaudet, L.6
  • 94
    • 0037424211 scopus 로고    scopus 로고
    • Contribution of endocannabinoids in the endothelial protection afforded by ischemic preconditioning in the isolated rat heart
    • DOI 10.1016/S0024-3205(02)02474-8
    • J.F. Bouchard, P. Lepicier, and D. Lamontagne Contribution of endocannabinoids in the endothelial protection afforded by ischemic preconditioning in the isolated rat heart Life Sci 72 2003 1859 1870 (Pubitemid 36174022)
    • (2003) Life Sciences , vol.72 , Issue.16 , pp. 1859-1870
    • Bouchard, J.-F.1    Lepicier, P.2    Lamontagne, D.3
  • 97
    • 40149084635 scopus 로고    scopus 로고
    • Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet
    • DOI 10.1038/oby.2007.106, PII OBY2007106
    • K.M. Starowicz, L. Cristino, I. Matias, R. Capasso, A. Racioppi, and A.A. Izzo Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet Obesity (Silver Spring) 16 2008 553 565 (Pubitemid 351328005)
    • (2008) Obesity , vol.16 , Issue.3 , pp. 553-565
    • Starowicz, K.M.1    Cristino, L.2    Matias, I.3    Capasso, R.4    Racioppi, A.5    Izzo, A.A.6    Di Marzo, V.7
  • 99
    • 47049123545 scopus 로고    scopus 로고
    • Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells
    • C.W. Michalski, M. Maier, M. Erkan, D. Sauliunaite, F. Bergmann, and P. Pacher Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells PLoS One 3 2008 e1701
    • (2008) PLoS One , vol.3 , pp. 1701
    • Michalski, C.W.1    Maier, M.2    Erkan, M.3    Sauliunaite, D.4    Bergmann, F.5    Pacher, P.6
  • 101
    • 78649624505 scopus 로고    scopus 로고
    • Cannabinoid agonist WIN55, 212 in vitro inhibits interleukin-6 (IL-6) and monocyte chemo-attractant protein-1 (MCP-1) release by rat pancreatic acini and in vivo induces dual effects on the course of acute pancreatitis
    • C. Petrella, S. Agostini, G.S. Alema, P. Casolini, F. Carpino, and C. Giuli Cannabinoid agonist WIN55, 212 in vitro inhibits interleukin-6 (IL-6) and monocyte chemo-attractant protein-1 (MCP-1) release by rat pancreatic acini and in vivo induces dual effects on the course of acute pancreatitis Neurogastroenterol Motil 11 2010 1248 1256
    • (2010) Neurogastroenterol Motil , vol.11 , pp. 1248-1256
    • Petrella, C.1    Agostini, S.2    Alema, G.S.3    Casolini, P.4    Carpino, F.5    Giuli, C.6
  • 102
    • 35348946336 scopus 로고    scopus 로고
    • 2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion
    • 2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion Am J Physiol Heart Circ Physiol 293 2007 H2210 H2218
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Rajesh, M.1    Mukhopadhyay, P.2    Batkai, S.3    Hasko, G.4    Liaudet, L.5    Huffman, J.W.6
  • 103
    • 37249091964 scopus 로고    scopus 로고
    • Pivotal Advance: Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis
    • DOI 10.1189/jlb.0307180
    • M. Rajesh, H. Pan, P. Mukhopadhyay, S. Batkai, D. Osei-Hyiaman, and G. Hasko Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis J Leukoc Biol 82 2007 1382 1389 (Pubitemid 350276948)
    • (2007) Journal of Leukocyte Biology , vol.82 , Issue.6 , pp. 1382-1389
    • Rajesh, M.1    Pan, H.2    Mukhopadhyay, P.3    Batkai, S.4    Osei-Hyiaman, D.5    Hasko, G.6    Liaudet, L.7    Gao, B.8    Pacher, P.9
  • 104
    • 79952769649 scopus 로고    scopus 로고
    • The manifold actions of endocannabinoids on female and male reproductive events
    • M. Bari, N. Battista, V. Pirazzi, and M. Maccarrone The manifold actions of endocannabinoids on female and male reproductive events Front Biosci 16 2011 498 516
    • (2011) Front Biosci , vol.16 , pp. 498-516
    • Bari, M.1    Battista, N.2    Pirazzi, V.3    MacCarrone, M.4
  • 106
    • 1542283728 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: Involvement of cytokine/chemokines and PMN
    • DOI 10.1189/jlb.0703303
    • 2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN J Leukoc Biol 75 2004 453 459 (Pubitemid 38316376)
    • (2004) Journal of Leukocyte Biology , vol.75 , Issue.3 , pp. 453-459
    • Di Filippo, C.1    Rossi, F.2    Rossi, S.3    D'Amico, M.4
  • 107
    • 38349144914 scopus 로고    scopus 로고
    • Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning
    • P. Pacher, and G. Hasko Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning Br J Pharmacol 153 2008 252 262
    • (2008) Br J Pharmacol , vol.153 , pp. 252-262
    • Pacher, P.1    Hasko, G.2
  • 109
    • 68549123561 scopus 로고    scopus 로고
    • The cannabinoid receptor type 2 promotes cardiac myocyte and fibroblast survival and protects against ischemia/reperfusion-induced cardiomyopathy
    • N. Defer, J. Wan, R. Souktani, B. Escoubet, M. Perier, and P. Caramelle The cannabinoid receptor type 2 promotes cardiac myocyte and fibroblast survival and protects against ischemia/reperfusion-induced cardiomyopathy FASEB J 23 2009 2120 2130
    • (2009) FASEB J , vol.23 , pp. 2120-2130
    • Defer, N.1    Wan, J.2    Souktani, R.3    Escoubet, B.4    Perier, M.5    Caramelle, P.6
  • 111
    • 67449165616 scopus 로고    scopus 로고
    • Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis
    • F. Montecucco, I. Matias, S. Lenglet, S. Petrosino, F. Burger, and G. Pelli Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis Atherosclerosis 205 2009 433 441
    • (2009) Atherosclerosis , vol.205 , pp. 433-441
    • Montecucco, F.1    Matias, I.2    Lenglet, S.3    Petrosino, S.4    Burger, F.5    Pelli, G.6
  • 112
    • 42349116948 scopus 로고    scopus 로고
    • The role of the endocannabinoid system in atherosclerosis
    • DOI 10.1111/j.1365-2826.2008.01685.x
    • F. Mach, and S. Steffens The role of the endocannabinoid system in atherosclerosis J Neuroendocrinol 20 Suppl. 1 2008 53 57 (Pubitemid 351552677)
    • (2008) Journal of Neuroendocrinology , vol.20 , Issue.SUPPL. 1 , pp. 53-57
    • Mach, F.1    Steffens, S.2
  • 114
  • 115
    • 41549162387 scopus 로고    scopus 로고
    • 2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways
    • 2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways Am J Physiol Heart Circ Physiol 294 2008 H1145 H1155
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Montecucco, F.1    Burger, F.2    MacH, F.3    Steffens, S.4
  • 116
    • 41549145722 scopus 로고    scopus 로고
    • 2 cannabinoid receptor activation on human monocyte migration: Implications for atherosclerosis and inflammatory diseases
    • 2 cannabinoid receptor activation on human monocyte migration: implications for atherosclerosis and inflammatory diseases Am J Physiol Heart Circ Physiol 294 2008 H1133 H1134
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Pacher, P.1    Ungvari, Z.2
  • 117
    • 59049102067 scopus 로고    scopus 로고
    • Activated endocannabinoid system in coronary artery disease and antiinflammatory effects of cannabinoid 1 receptor blockade on macrophages
    • K. Sugamura, S. Sugiyama, T. Nozaki, Y. Matsuzawa, Y. Izumiya, and K. Miyata Activated endocannabinoid system in coronary artery disease and antiinflammatory effects of cannabinoid 1 receptor blockade on macrophages Circulation 119 2009 28 36
    • (2009) Circulation , vol.119 , pp. 28-36
    • Sugamura, K.1    Sugiyama, S.2    Nozaki, T.3    Matsuzawa, Y.4    Izumiya, Y.5    Miyata, K.6
  • 119
    • 52949119940 scopus 로고    scopus 로고
    • Role of cannabinoids and endocannabinoids in cerebral ischemia
    • C.J. Hillard Role of cannabinoids and endocannabinoids in cerebral ischemia Curr Pharm Des 14 2008 2347 2361
    • (2008) Curr Pharm des , vol.14 , pp. 2347-2361
    • Hillard, C.J.1
  • 120
    • 8444250235 scopus 로고    scopus 로고
    • 1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia
    • DOI 10.1016/j.neuroscience.2004.08.044, PII S0306452204007687
    • 1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia Neuroscience 129 2004 743 750 (Pubitemid 39487125)
    • (2004) Neuroscience , vol.129 , Issue.3 , pp. 743-750
    • Muthian, S.1    Rademacher, D.J.2    Roelke, C.T.3    Gross, G.J.4    Hillard, C.J.5
  • 121
  • 122
    • 40949116660 scopus 로고    scopus 로고
    • Modulation of the balance between cannabinoid CB(1) and CB(2) receptor activation during cerebral ischemic/reperfusion injury
    • M. Zhang, B.R. Martin, M.W. Adler, R.K. Razdan, D. Ganea, and R.F. Tuma Modulation of the balance between cannabinoid CB(1) and CB(2) receptor activation during cerebral ischemic/reperfusion injury Neuroscience 152 2008 753 760
    • (2008) Neuroscience , vol.152 , pp. 753-760
    • Zhang, M.1    Martin, B.R.2    Adler, M.W.3    Razdan, R.K.4    Ganea, D.5    Tuma, R.F.6
  • 123
    • 65349186523 scopus 로고    scopus 로고
    • 2 receptor activation attenuates motor and autonomic function deficits in a mouse model of spinal cord injury
    • 2 receptor activation attenuates motor and autonomic function deficits in a mouse model of spinal cord injury Clin Neurosurg 55 2008 172 177
    • (2008) Clin Neurosurg , vol.55 , pp. 172-177
    • Baty, D.E.1    Zhang, M.2    Li, H.3    Erb, C.J.4    Adler, M.W.5    Ganea, D.6
  • 124
    • 77952302634 scopus 로고    scopus 로고
    • Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment
    • S. Murikinati, E. Juttler, T. Keinert, D.A. Ridder, S. Muhammad, and Z. Waibler Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment FASEB J 24 2010 788 798
    • (2010) FASEB J , vol.24 , pp. 788-798
    • Murikinati, S.1    Juttler, E.2    Keinert, T.3    Ridder, D.A.4    Muhammad, S.5    Waibler, Z.6
  • 125
    • 77956552524 scopus 로고    scopus 로고
    • Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure
    • F. Weis, A. Beiras-Fernandez, R. Sodian, I. Kaczmarek, B. Reichart, and A. Beiras Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure J Mol Cell Cardiol 48 2010 1187 1193
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 1187-1193
    • Weis, F.1    Beiras-Fernandez, A.2    Sodian, R.3    Kaczmarek, I.4    Reichart, B.5    Beiras, A.6
  • 126
    • 4444374031 scopus 로고    scopus 로고
    • Reductions in levels of bacterial superantigens/cannabinoids by plasma exchange in a patient with severe toxic shock syndrome
    • S. Kohro, H. Imaizumi, M. Yamakage, Y. Masuda, A. Namiki, and Y. Asai Reductions in levels of bacterial superantigens/cannabinoids by plasma exchange in a patient with severe toxic shock syndrome Anaesth Intensive Care 32 2004 588 591 (Pubitemid 39172468)
    • (2004) Anaesthesia and Intensive Care , vol.32 , Issue.4 , pp. 588-591
    • Kohro, S.1    Imaizumi, H.2    Yamakage, M.3    Masuda, Y.4    Namiki, A.5    Asai, Y.6
  • 127
    • 31144434923 scopus 로고    scopus 로고
    • Anandamide absorption by direct hemoperfusion with polymixin B-immobilized fiber improves the prognosis and organ failure assessment score in patients with sepsis
    • DOI 10.1007/s00540-005-0366-5
    • S. Kohro, H. Imaizumi, M. Yamakage, Y. Masuda, A. Namiki, and Y. Asai Anandamide absorption by direct hemoperfusion with polymixin B-immobilized fiber improves the prognosis and organ failure assessment score in patients with sepsis J Anesth 20 2006 11 16 (Pubitemid 43125774)
    • (2006) Journal of Anesthesia , vol.20 , Issue.1 , pp. 11-16
    • Kohro, S.1    Imaizumi, H.2    Yamakage, M.3    Masuda, Y.4    Namiki, A.5    Asai, Y.6    Maruyama, I.7
  • 132
    • 77951622108 scopus 로고    scopus 로고
    • F2-isoprostanes and 2-arachidonylglycerol as biomarkers of lipid peroxidation in pigs with hepatic ischemia/reperfusion injury
    • Y. Ishii, T. Sakamoto, R. Ito, and K. Yanaga F2-isoprostanes and 2-arachidonylglycerol as biomarkers of lipid peroxidation in pigs with hepatic ischemia/reperfusion injury J Surg Res 161 2010 139 145
    • (2010) J Surg Res , vol.161 , pp. 139-145
    • Ishii, Y.1    Sakamoto, T.2    Ito, R.3    Yanaga, K.4
  • 133
    • 45749086074 scopus 로고    scopus 로고
    • Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: Involvement of regulatory T cells
    • DOI 10.1124/mol.108.047035
    • V.L. Hegde, S. Hegde, B.F. Cravatt, L.J. Hofseth, M. Nagarkatti, and P.S. Nagarkatti Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells Mol Pharmacol 74 2008 20 33 (Pubitemid 351872155)
    • (2008) Molecular Pharmacology , vol.74 , Issue.1 , pp. 20-33
    • Hegde, V.L.1    Hegde, S.2    Cravatt, B.F.3    Hofseth, L.J.4    Nagarkatti, M.5    Nagarkatti, P.S.6
  • 138
    • 78649331179 scopus 로고    scopus 로고
    • 2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age
    • 2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age Diabetologia 53 2010 2629 2640
    • (2010) Diabetologia , vol.53 , pp. 2629-2640
    • Agudo, J.1    Martin, M.2    Roca, C.3    Molas, M.4    Bura, A.S.5    Zimmer, A.6
  • 140
    • 39149111268 scopus 로고    scopus 로고
    • Endocannabinoids and liver disease. II. Endocannabinoids in the pathogenesis and treatment of liver fibrosis
    • S.V. Siegmund, and R.F. Schwabe Endocannabinoids and liver disease. II. Endocannabinoids in the pathogenesis and treatment of liver fibrosis Am J Physiol Gastrointest Liver Physiol 294 2008 G357 G362
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Siegmund, S.V.1    Schwabe, R.F.2
  • 143
    • 57349199296 scopus 로고    scopus 로고
    • Endocannabinoids and liver disease. V. endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis
    • L. Moezi, S.A. Gaskari, and S.S. Lee Endocannabinoids and liver disease. V. endocannabinoids as mediators of vascular and cardiac abnormalities in cirrhosis Am J Physiol Gastrointest Liver Physiol 295 2008 G649 G653
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.295
    • Moezi, L.1    Gaskari, S.A.2    Lee, S.S.3
  • 144
    • 67449123056 scopus 로고    scopus 로고
    • Endocannabinoids and cardiac contractile function: Pathophysiological implications
    • S. Batkai, and P. Pacher Endocannabinoids and cardiac contractile function: pathophysiological implications Pharmacol Res 60 2009 99 106
    • (2009) Pharmacol Res , vol.60 , pp. 99-106
    • Batkai, S.1    Pacher, P.2
  • 145
    • 77956644099 scopus 로고    scopus 로고
    • Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration
    • F. Teixeira-Clerc, M.P. Belot, S. Manin, V. Deveaux, T. Cadoudal, and M.N. Chobert Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration Hepatology 52 3 2010 1046 1059
    • (2010) Hepatology , vol.52 , Issue.3 , pp. 1046-1059
    • Teixeira-Clerc, F.1    Belot, M.P.2    Manin, S.3    Deveaux, V.4    Cadoudal, T.5    Chobert, M.N.6
  • 147
    • 34547823575 scopus 로고    scopus 로고
    • Cannabinoids ameliorate cerebral dysfunction following liver failure via AMP-activated protein kinase
    • DOI 10.1096/fj.06-7705com
    • Y. Dagon, Y. Avraham, Y. Ilan, R. Mechoulam, and E.M. Berry Cannabinoids ameliorate cerebral dysfunction following liver failure via AMP-activated protein kinase FASEB J 21 2007 2431 2441 (Pubitemid 47230673)
    • (2007) FASEB Journal , vol.21 , Issue.10 , pp. 2431-2441
    • Dagon, Y.1    Avraham, Y.2    Ilan, Y.3    Mechoulam, R.4    Berry, E.M.5
  • 148
    • 52949141093 scopus 로고    scopus 로고
    • Endocannabinoids in liver disease and hepatic encephalopathy
    • I. Magen, Y. Avraham, E. Berry, and R. Mechoulam Endocannabinoids in liver disease and hepatic encephalopathy Curr Pharm Des 14 2008 2362 2369
    • (2008) Curr Pharm des , vol.14 , pp. 2362-2369
    • Magen, I.1    Avraham, Y.2    Berry, E.3    Mechoulam, R.4
  • 149
    • 61649124735 scopus 로고    scopus 로고
    • Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance
    • F. Borrelli, and A.A. Izzo Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance Best Pract Res Clin Endocrinol Metab 23 2009 33 49
    • (2009) Best Pract Res Clin Endocrinol Metab , vol.23 , pp. 33-49
    • Borrelli, F.1    Izzo, A.A.2
  • 150
    • 23244457833 scopus 로고    scopus 로고
    • Differential expression of cannabinoid receptors in the human colon: Cannabinoids promote epithelial wound healing
    • DOI 10.1016/j.gastro.2005.05.026, PII S0016508505009297
    • K. Wright, N. Rooney, M. Feeney, J. Tate, D. Robertson, and M. Welham Differential expression of cannabinoid receptors in the human colon: cannabinoids promote epithelial wound healing Gastroenterology 129 2005 437 453 (Pubitemid 41096632)
    • (2005) Gastroenterology , vol.129 , Issue.2 , pp. 437-453
    • Wright, K.1    Rooney, N.2    Feeney, M.3    Tate, J.4    Robertson, D.5    Welham, M.6    Ward, S.7
  • 151
    • 33745783119 scopus 로고    scopus 로고
    • Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium
    • E.S. Kimball, C.R. Schneider, N.H. Wallace, and P.J. Hornby Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium Am J Physiol Gastrointest Liver Physiol 291 2006 G364 G371
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.291
    • Kimball, E.S.1    Schneider, C.R.2    Wallace, N.H.3    Hornby, P.J.4
  • 156
    • 78049275914 scopus 로고    scopus 로고
    • Oleoyl serine, an endogenous N-acyl amide, modulates bone remodeling and mass
    • R. Smoum, A. Bar, B. Tan, G. Milman, M. Attar-Namdar, and O. Ofek Oleoyl serine, an endogenous N-acyl amide, modulates bone remodeling and mass Proc Natl Acad Sci USA 107 2010 17710 17715
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 17710-17715
    • Smoum, R.1    Bar, A.2    Tan, B.3    Milman, G.4    Attar-Namdar, M.5    Ofek, O.6
  • 159
    • 14244264502 scopus 로고    scopus 로고
    • Prevention of Alzheimer's disease pathology by cannabinoids: Neuroprotection mediated by blockade of microglial activation
    • DOI 10.1523/JNEUROSCI.4540-04.2005
    • B.G. Ramirez, C. Blazquez, T. Gomez del Pulgar, M. Guzman, and M.L. de Ceballos Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation J Neurosci 25 2005 1904 1913 (Pubitemid 40289395)
    • (2005) Journal of Neuroscience , vol.25 , Issue.8 , pp. 1904-1913
    • Ramirez, B.G.1    Blazquez, C.2    Gomez Del Pulgar, T.3    Guzman, M.4    De Ceballos, M.L.5
  • 162
    • 33746261289 scopus 로고    scopus 로고
    • 2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis
    • DOI 10.1016/j.ejphar.2006.05.025, PII S0014299906005103
    • 2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis Eur J Pharmacol 542 2006 100 105 (Pubitemid 44096919)
    • (2006) European Journal of Pharmacology , vol.542 , Issue.1-3 , pp. 100-105
    • Kim, K.1    Moore, D.H.2    Makriyannis, A.3    Abood, M.E.4
  • 163
    • 33947278309 scopus 로고    scopus 로고
    • The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset
    • DOI 10.1111/j.1471-4159.2006.04346.x
    • 2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset J Neurochem 101 2007 87 98 (Pubitemid 46426470)
    • (2007) Journal of Neurochemistry , vol.101 , Issue.1 , pp. 87-98
    • Shoemaker, J.L.1    Seely, K.A.2    Reed, R.L.3    Crow, J.P.4    Prather, P.L.5
  • 164
    • 66449132820 scopus 로고    scopus 로고
    • WIN55, 212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
    • D.A. Price, A.A. Martinez, A. Seillier, W. Koek, Y. Acosta, and E. Fernandez WIN55, 212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease Eur J Neurosci 29 2009 2177 2186
    • (2009) Eur J Neurosci , vol.29 , pp. 2177-2186
    • Price, D.A.1    Martinez, A.A.2    Seillier, A.3    Koek, W.4    Acosta, Y.5    Fernandez, E.6
  • 167
    • 45149123400 scopus 로고    scopus 로고
    • The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: Involvement in the pathogenesis of an animal model of multiple sclerosis
    • J. Palazuelos, N. Davoust, B. Julien, E. Hatterer, T. Aguado, and R. Mechoulam The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis J Biol Chem 283 2008 13320 13329
    • (2008) J Biol Chem , vol.283 , pp. 13320-13329
    • Palazuelos, J.1    Davoust, N.2    Julien, B.3    Hatterer, E.4    Aguado, T.5    Mechoulam, R.6
  • 170
    • 41049103782 scopus 로고    scopus 로고
    • Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions
    • Z. De March, C. Zuccato, C. Giampa, S. Patassini, M. Bari, and V. Gasperi Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions Neuroscience 152 2008 734 740
    • (2008) Neuroscience , vol.152 , pp. 734-740
    • De March, Z.1    Zuccato, C.2    Giampa, C.3    Patassini, S.4    Bari, M.5    Gasperi, V.6
  • 171
    • 59049099828 scopus 로고    scopus 로고
    • A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules
    • L. Mestre, F. Docagne, F. Correa, F. Loria, M. Hernangomez, and J. Borrell A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules Mol Cell Neurosci 40 2009 258 266
    • (2009) Mol Cell Neurosci , vol.40 , pp. 258-266
    • Mestre, L.1    Docagne, F.2    Correa, F.3    Loria, F.4    Hernangomez, M.5    Borrell, J.6
  • 172
    • 70449518017 scopus 로고    scopus 로고
    • An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis
    • F. Loria, S. Petrosino, M. Hernangomez, L. Mestre, A. Spagnolo, and F. Correa An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis Neurobiol Dis 37 2010 166 176
    • (2010) Neurobiol Dis , vol.37 , pp. 166-176
    • Loria, F.1    Petrosino, S.2    Hernangomez, M.3    Mestre, L.4    Spagnolo, A.5    Correa, F.6
  • 173
    • 33644804271 scopus 로고    scopus 로고
    • The therapeutic potential of drugs that target cannabinoid receptors or modulate the tissue levels or actions of endocannabinoids
    • R.G. Pertwee The therapeutic potential of drugs that target cannabinoid receptors or modulate the tissue levels or actions of endocannabinoids AAPS J 7 2005 E625 E654
    • (2005) AAPS J , vol.7
    • Pertwee, R.G.1
  • 174
    • 78649233198 scopus 로고    scopus 로고
    • Cannabinoid receptors and endocannabinoids: Role in neuroinflammatory and neurodegenerative disorders
    • T. Bisogno, and V. Di Marzo Cannabinoid receptors and endocannabinoids: role in neuroinflammatory and neurodegenerative disorders CNS Neurol Disord Drug Targets 9 5 2010 564 573
    • (2010) CNS Neurol Disord Drug Targets , vol.9 , Issue.5 , pp. 564-573
    • Bisogno, T.1    Di Marzo, V.2
  • 175
    • 77953712552 scopus 로고    scopus 로고
    • Modulation of the endocannabinoid system: Neuroprotection or neurotoxicity?
    • C.J. Fowler, M.L. Rojo, and A. Rodriguez-Gaztelumendi Modulation of the endocannabinoid system: neuroprotection or neurotoxicity? Exp Neurol 224 2010 37 47
    • (2010) Exp Neurol , vol.224 , pp. 37-47
    • Fowler, C.J.1    Rojo, M.L.2    Rodriguez-Gaztelumendi, A.3
  • 177
    • 0032537734 scopus 로고    scopus 로고
    • Control of pain initiation by endogenous cannabinoids
    • DOI 10.1038/28393
    • A. Calignano, G. La Rana, A. Giuffrida, and D. Piomelli Control of pain initiation by endogenous cannabinoids Nature 394 1998 277 281 (Pubitemid 28335039)
    • (1998) Nature , vol.394 , Issue.6690 , pp. 277-281
    • Calignano, A.1    La Rana, G.2    Giuffrida, A.3    Piomelli, D.4
  • 180
    • 0036221971 scopus 로고    scopus 로고
    • CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
    • DOI 10.1016/S0304-3959(01)00454-7, PII S0304395901004547
    • 2 cannabinoid receptors are implicated in inflammatory pain Pain 96 2002 253 260 (Pubitemid 34327871)
    • (2002) Pain , vol.96 , Issue.3 , pp. 253-260
    • Clayton, N.1    Marshall, F.H.2    Bountra, C.3    O'Shaughnessy, C.T.4
  • 184
    • 0038521050 scopus 로고    scopus 로고
    • 2 receptors suppresses spinal Fos protein expression and pain behavior in a rat model of inflammation
    • DOI 10.1016/S0306-4522(03)00126-X
    • A.G. Nackley, A. Makriyannis, and A.G. Hohmann Selective activation of cannabinoid CB(2) receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation Neuroscience 119 2003 747 757 (Pubitemid 36694801)
    • (2003) Neuroscience , vol.119 , Issue.3 , pp. 747-757
    • Nackley, A.G.1    Makriyannis, A.2    Hohmann, A.G.3
  • 185
    • 0037475146 scopus 로고    scopus 로고
    • A peripheral cannabinoid mechanism suppresses spinal Fos protein expression and pain behavior in a rat model of inflammation
    • DOI 10.1016/S0306-4522(02)00870-9
    • A.G. Nackley, R.L. Suplita 2nd, and A.G. Hohmann A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation Neuroscience 117 2003 659 670 (Pubitemid 36263159)
    • (2003) Neuroscience , vol.117 , Issue.3 , pp. 659-670
    • Nackley, A.G.1    Suplita II, R.L.2    Hohmann, A.G.3
  • 186
    • 8644274638 scopus 로고    scopus 로고
    • 2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation
    • DOI 10.1152/jn.00886.2003
    • 2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation J Neurophysiol 92 2004 3562 3574 (Pubitemid 39506332)
    • (2004) Journal of Neurophysiology , vol.92 , Issue.6 , pp. 3562-3574
    • Nackley, A.G.1    Zvonok, A.M.2    Makriyannis, A.3    Hohmann, A.G.4
  • 188
    • 8144229133 scopus 로고    scopus 로고
    • 2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of inflammatory and neuropathic pain
    • DOI 10.1111/j.1460-9568.2004.03690.x
    • 2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naive rats and in rat models of inflammatory and neuropathic pain Eur J Neurosci 20 2004 2311 2320 (Pubitemid 39472394)
    • (2004) European Journal of Neuroscience , vol.20 , Issue.9 , pp. 2311-2320
    • Elmes, S.J.R.1    Jhaveri, M.D.2    Smart, D.3    Kendall, D.A.4    Chapman, V.5
  • 190
    • 1842685334 scopus 로고    scopus 로고
    • Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat
    • DOI 10.1016/j.pain.2004.01.020, PII S030439590400051X
    • D.A. Scott, C.E. Wright, and J.A. Angus Evidence that CB-1 and CB-2 cannabinoid receptors mediate antinociception in neuropathic pain in the rat Pain 109 2004 124 131 (Pubitemid 38479778)
    • (2004) Pain , vol.109 , Issue.1-2 , pp. 124-131
    • Scott, D.A.1    Wright, C.E.2    Angus, J.A.3
  • 191
    • 34247862287 scopus 로고    scopus 로고
    • The role of the cannabinoid CB2 receptor in pain transmission and therapeutic potential of small molecule CB2 receptor agonists
    • DOI 10.2174/092986707780363023
    • 2 receptor agonists Curr Med Chem 14 2007 917 936 (Pubitemid 46863619)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.8 , pp. 917-936
    • Whiteside, G.T.1    Lee, G.P.2    Valenzano, K.J.3
  • 193
    • 70349333074 scopus 로고    scopus 로고
    • Cannabinoids as pharmacotherapies for neuropathic pain: From the bench to the bedside
    • E.J. Rahn, and A.G. Hohmann Cannabinoids as pharmacotherapies for neuropathic pain: from the bench to the bedside Neurotherapeutics 6 2009 713 737
    • (2009) Neurotherapeutics , vol.6 , pp. 713-737
    • Rahn, E.J.1    Hohmann, A.G.2
  • 194
    • 46949099370 scopus 로고    scopus 로고
    • Cannabis and schizophrenia: Towards a cannabinoid hypothesis of schizophrenia
    • DOI 10.1586/14737175.8.7.1037
    • K.R. Muller-Vahl, and H.M. Emrich Cannabis and schizophrenia: towards a cannabinoid hypothesis of schizophrenia Expert Rev Neurother 8 2008 1037 1048 (Pubitemid 351962072)
    • (2008) Expert Review of Neurotherapeutics , vol.8 , Issue.7 , pp. 1037-1048
    • Muiller-Vahl, K.R.1    Emrich, H.M.2
  • 195
    • 0000735519 scopus 로고
    • Cannabis and schizophrenia. A longitudinal study of Swedish conscripts
    • S. Andreasson, P. Allebeck, A. Engstrom, and U. Rydberg Cannabis and schizophrenia. A longitudinal study of Swedish conscripts Lancet 2 1987 1483 1486
    • (1987) Lancet , vol.2 , pp. 1483-1486
    • Andreasson, S.1    Allebeck, P.2    Engstrom, A.3    Rydberg, U.4
  • 197
    • 0029021076 scopus 로고
    • Marihuana as medicine. A plea for reconsideration
    • L. Grinspoon, and J.B. Bakalar Marihuana as medicine. A plea for reconsideration JAMA 273 1995 1875 1876
    • (1995) JAMA , vol.273 , pp. 1875-1876
    • Grinspoon, L.1    Bakalar, J.B.2
  • 200
    • 33845811458 scopus 로고    scopus 로고
    • 2 receptors in the IgE-mediated triphasic cutaneous reaction in mice
    • DOI 10.1016/j.lfs.2006.09.026, PII S0024320506007466
    • 2 receptors in the IgE-mediated triphasic cutaneous reaction in mice Life Sci 80 2007 414 419 (Pubitemid 46013906)
    • (2007) Life Sciences , vol.80 , Issue.5 , pp. 414-419
    • Ueda, Y.1    Miyagawa, N.2    Wakitani, K.3
  • 203
    • 77954574870 scopus 로고    scopus 로고
    • Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis
    • A. Servettaz, N. Kavian, C. Nicco, V. Deveaux, C. Chereau, and A. Wang Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis Am J Pathol 177 2010 187 196
    • (2010) Am J Pathol , vol.177 , pp. 187-196
    • Servettaz, A.1    Kavian, N.2    Nicco, C.3    Deveaux, V.4    Chereau, C.5    Wang, A.6
  • 204
    • 43249115359 scopus 로고    scopus 로고
    • Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis
    • D. Richardson, R.G. Pearson, N. Kurian, M.L. Latif, M.J. Garle, and D.A. Barrett Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis Arthritis Res Ther 10 2008 R43
    • (2008) Arthritis Res Ther , vol.10 , pp. 43
    • Richardson, D.1    Pearson, R.G.2    Kurian, N.3    Latif, M.L.4    Garle, M.J.5    Barrett, D.A.6
  • 205
    • 20444382826 scopus 로고    scopus 로고
    • The cannabinoid receptor agonist WIN 55212-2 inhibits neurogenic inflammations in airway tissues
    • DOI 10.1254/jphs.FP0050171
    • S. Yoshihara, H. Morimoto, M. Ohori, Y. Yamada, T. Abe, and O. Arisaka The cannabinoid receptor agonist WIN 55212-2 inhibits neurogenic inflammations in airway tissues J Pharmacol Sci 98 2005 77 82 (Pubitemid 40806130)
    • (2005) Journal of Pharmacological Sciences , vol.98 , Issue.1 , pp. 77-82
    • Yoshihara, S.1    Morimoto, H.2    Ohori, M.3    Yamada, Y.4    Abe, T.5    Arisaka, O.6
  • 206
    • 76249102815 scopus 로고    scopus 로고
    • The cannabinoid receptor agonist WIN 55, 212-2 inhibits antigen-induced plasma extravasation in guinea pig airways
    • H. Fukuda, T. Abe, and S. Yoshihara The cannabinoid receptor agonist WIN 55, 212-2 inhibits antigen-induced plasma extravasation in guinea pig airways Int Arch Allergy Immunol 152 2010 295 300
    • (2010) Int Arch Allergy Immunol , vol.152 , pp. 295-300
    • Fukuda, H.1    Abe, T.2    Yoshihara, S.3
  • 208
    • 45549095987 scopus 로고    scopus 로고
    • The cannabinoid receptors are required for ultraviolet-induced inflammation and skin cancer development
    • D. Zheng, A.M. Bode, Q. Zhao, Y.Y. Cho, F. Zhu, and W.Y. Ma The cannabinoid receptors are required for ultraviolet-induced inflammation and skin cancer development Cancer Res 68 2008 3992 3998
    • (2008) Cancer Res , vol.68 , pp. 3992-3998
    • Zheng, D.1    Bode, A.M.2    Zhao, Q.3    Cho, Y.Y.4    Zhu, F.5    Ma, W.Y.6
  • 212
    • 34548446421 scopus 로고    scopus 로고
    • Anti-inflammatory property of the cannabinoid receptor-2-selective agonist JWH-133 in a rodent model of autoimmune uveoretinitis
    • DOI 10.1189/jlb.0307159
    • H. Xu, C.L. Cheng, M. Chen, A. Manivannan, L. Cabay, and R.G. Pertwee Anti-inflammatory property of the cannabinoid receptor-2-selective agonist JWH-133 in a rodent model of autoimmune uveoretinitis J Leukoc Biol 82 2007 532 541 (Pubitemid 47367143)
    • (2007) Journal of Leukocyte Biology , vol.82 , Issue.3 , pp. 532-541
    • Xu, H.1    Cheng, C.L.2    Chen, M.3    Manivannan, A.4    Cabay, L.5    Pertwee, R.G.6    Coutts, A.7    Forrester, J.V.8
  • 213
  • 216
    • 48149101434 scopus 로고    scopus 로고
    • The endocannabinoid system in obesity and type 2 diabetes
    • V. Di Marzo The endocannabinoid system in obesity and type 2 diabetes Diabetologia 51 2008 1356 1367
    • (2008) Diabetologia , vol.51 , pp. 1356-1367
    • Di Marzo, V.1
  • 217
  • 218
    • 78650716667 scopus 로고    scopus 로고
    • Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury
    • P. Mukhopadhyay, B. Horvath, M. Rajesh, S. Matsumoto, K. Saito, and S. Batkai Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury Free Radic Biol Med 50 1 2011 179 195
    • (2011) Free Radic Biol Med , vol.50 , Issue.1 , pp. 179-195
    • Mukhopadhyay, P.1    Horvath, B.2    Rajesh, M.3    Matsumoto, S.4    Saito, K.5    Batkai, S.6
  • 220
    • 58849130978 scopus 로고    scopus 로고
    • 1 receptor antagonists for atherosclerosis and cardiometabolic disorders: New hopes, old concerns?
    • 1 receptor antagonists for atherosclerosis and cardiometabolic disorders: new hopes, old concerns? Arterioscler Thromb Vasc Biol 29 2009 7 9
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 7-9
    • Pacher, P.1
  • 221
    • 38349093269 scopus 로고    scopus 로고
    • Cannabinoid receptors in acute and chronic complications of atherosclerosis
    • F. Mach, F. Montecucco, and S. Steffens Cannabinoid receptors in acute and chronic complications of atherosclerosis Br J Pharmacol 153 2008 290 298
    • (2008) Br J Pharmacol , vol.153 , pp. 290-298
    • MacH, F.1    Montecucco, F.2    Steffens, S.3
  • 223
    • 67650360196 scopus 로고    scopus 로고
    • Endocannabinoids and the heart
    • C.R. Hiley Endocannabinoids and the heart J Cardiovasc Pharmacol 53 2009 267 276
    • (2009) J Cardiovasc Pharmacol , vol.53 , pp. 267-276
    • Hiley, C.R.1
  • 224
    • 70849114191 scopus 로고    scopus 로고
    • 2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages
    • 2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages Cardiovasc Res 84 2009 378 386
    • (2009) Cardiovasc Res , vol.84 , pp. 378-386
    • Han, K.H.1    Lim, S.2    Ryu, J.3    Lee, C.W.4    Kim, Y.5    Kang, J.H.6
  • 228
    • 58149402426 scopus 로고    scopus 로고
    • Cannabinoids and capsaicin improve liver function following thioacetamide-induced acute injury in mice
    • Y. Avraham, O. Zolotarev, N.C. Grigoriadis, T. Poutahidis, I. Magen, and L. Vorobiav Cannabinoids and capsaicin improve liver function following thioacetamide-induced acute injury in mice Am J Gastroenterol 103 2008 3047 3056
    • (2008) Am J Gastroenterol , vol.103 , pp. 3047-3056
    • Avraham, Y.1    Zolotarev, O.2    Grigoriadis, N.C.3    Poutahidis, T.4    Magen, I.5    Vorobiav, L.6
  • 231
    • 33644631485 scopus 로고    scopus 로고
    • Therapeutic effects of xanthine oxidase inhibitors: Renaissance half a century after the discovery of allopurinol
    • P. Pacher, A. Nivorozhkin, and C. Szabo Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol Pharmacol Rev 58 2006 87 114
    • (2006) Pharmacol Rev , vol.58 , pp. 87-114
    • Pacher, P.1    Nivorozhkin, A.2    Szabo, C.3
  • 232
    • 77957254806 scopus 로고    scopus 로고
    • Peroxisomal and microsomal lipid pathways associated with resistance to hepatic steatosis and reduced pro-inflammatory state
    • D. Hall, C. Poussin, V.R. Velagapudi, C. Empsen, M. Joffraud, and J. Beckmann Peroxisomal and microsomal lipid pathways associated with resistance to hepatic steatosis and reduced pro-inflammatory state J Biol Chem 285 40 2010 31011 31023
    • (2010) J Biol Chem , vol.285 , Issue.40 , pp. 31011-31023
    • Hall, D.1    Poussin, C.2    Velagapudi, V.R.3    Empsen, C.4    Joffraud, M.5    Beckmann, J.6
  • 233
    • 34548499520 scopus 로고    scopus 로고
    • The endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species
    • DOI 10.1096/fj.06-7717com
    • S.V. Siegmund, T. Qian, S. de Minicis, J. Harvey-White, G. Kunos, and K.Y. Vinod The endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species FASEB J 21 2007 2798 2806 (Pubitemid 47372747)
    • (2007) FASEB Journal , vol.21 , Issue.11 , pp. 2798-2806
    • Siegmund, S.V.1    Qian, T.2    De Minicis, S.3    Harvey-White, J.4    Kunos, G.5    Vinod, K.Y.6    Hungund, B.7    Schwabe, R.F.8
  • 234
    • 67651148004 scopus 로고    scopus 로고
    • Use of cannabinoids as a novel therapeutic modality against autoimmune hepatitis
    • R. Pandey, V.L. Hegde, N.P. Singh, L. Hofseth, U. Singh, and S. Ray Use of cannabinoids as a novel therapeutic modality against autoimmune hepatitis Vitam Horm 81 2009 487 504
    • (2009) Vitam Horm , vol.81 , pp. 487-504
    • Pandey, R.1    Hegde, V.L.2    Singh, N.P.3    Hofseth, L.4    Singh, U.5    Ray, S.6
  • 235
    • 38649116306 scopus 로고    scopus 로고
    • Endocannabinoids, CB1 Receptors, and Liver Disease: Hitting More Than One Bird With the Same Stone
    • DOI 10.1053/j.gastro.2007.12.017, PII S0016508507022007
    • 1 receptors, and liver disease: hitting more than one bird with the same stone Gastroenterology 134 2008 622 625 (Pubitemid 351173070)
    • (2008) Gastroenterology , vol.134 , Issue.2 , pp. 622-625
    • Kunos, G.1    Gao, B.2
  • 236
    • 33745020449 scopus 로고    scopus 로고
    • Cannabinoids hurt, heal in cirrhosis
    • DOI 10.1038/nm0606-608, PII N0606608
    • G. Kunos, D. Osei-Hyiaman, S. Batkai, and B. Gao Cannabinoids hurt, heal in cirrhosis Nat Med 12 2006 608 610 (Pubitemid 43869936)
    • (2006) Nature Medicine , vol.12 , Issue.6 , pp. 608-610
    • Kunos, G.1    Osei-Hyiaman, D.2    Batkai, S.3    Gao, B.4
  • 241
    • 0038688373 scopus 로고    scopus 로고
    • The complexities of skeletal biology
    • DOI 10.1038/nature01654
    • G. Karsenty The complexities of skeletal biology Nature 423 2003 316 318 (Pubitemid 40852704)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 316-318
    • Karsenty, G.1
  • 244
    • 59649083643 scopus 로고    scopus 로고
    • The endovanilloid/endocannabinoid system in human osteoclasts: Possible involvement in bone formation and resorption
    • F. Rossi, D. Siniscalco, L. Luongo, L. De Petrocellis, G. Bellini, and S. Petrosino The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption Bone 44 2009 476 484
    • (2009) Bone , vol.44 , pp. 476-484
    • Rossi, F.1    Siniscalco, D.2    Luongo, L.3    De Petrocellis, L.4    Bellini, G.5    Petrosino, S.6
  • 246
    • 34248585741 scopus 로고    scopus 로고
    • Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men
    • Y. Yamada, F. Ando, and H. Shimokata Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men Int J Mol Med 19 2007 791 801
    • (2007) Int J Mol Med , vol.19 , pp. 791-801
    • Yamada, Y.1    Ando, F.2    Shimokata, H.3
  • 248
    • 77956228507 scopus 로고    scopus 로고
    • Endocannabinoid signaling in neurotoxicity and neuroprotection
    • C. Pope, R. Mechoulam, and L. Parsons Endocannabinoid signaling in neurotoxicity and neuroprotection Neurotoxicology 31 5 2010 562 571
    • (2010) Neurotoxicology , vol.31 , Issue.5 , pp. 562-571
    • Pope, C.1    Mechoulam, R.2    Parsons, L.3
  • 251
    • 38349166157 scopus 로고    scopus 로고
    • The endocannabinoid system and Alzheimer's disease
    • DOI 10.1007/s12035-007-8006-8
    • C. Benito, E. Nunez, M.R. Pazos, R.M. Tolon, and J. Romero The endocannabinoid system and Alzheimer's disease Mol Neurobiol 36 2007 75 81 (Pubitemid 351360357)
    • (2007) Molecular Neurobiology , vol.36 , Issue.1 , pp. 75-81
    • Benito, C.1    Nunez, E.2    Pazos, M.R.3    Tolon, R.M.4    Romero, J.5
  • 252
    • 37849049077 scopus 로고    scopus 로고
    • Glial expression of cannabinoid CB(2) receptors and fatty acid amide hydrolase are beta amyloid-linked events in Down's syndrome
    • E. Nunez, C. Benito, R.M. Tolon, C.J. Hillard, W.S. Griffin, and J. Romero Glial expression of cannabinoid CB(2) receptors and fatty acid amide hydrolase are beta amyloid-linked events in Down's syndrome Neuroscience 151 2008 104 110
    • (2008) Neuroscience , vol.151 , pp. 104-110
    • Nunez, E.1    Benito, C.2    Tolon, R.M.3    Hillard, C.J.4    Griffin, W.S.5    Romero, J.6
  • 258
    • 70449629796 scopus 로고    scopus 로고
    • The acute effects of synthetic intravenous Delta9-tetrahydrocannabinol on psychosis, mood and cognitive functioning
    • P.D. Morrison, V. Zois, D.A. McKeown, T.D. Lee, D.W. Holt, and J.F. Powell The acute effects of synthetic intravenous Delta9-tetrahydrocannabinol on psychosis, mood and cognitive functioning Psychol Med 39 2009 1607 1616
    • (2009) Psychol Med , vol.39 , pp. 1607-1616
    • Morrison, P.D.1    Zois, V.2    McKeown, D.A.3    Lee, T.D.4    Holt, D.W.5    Powell, J.F.6
  • 260
    • 7044282933 scopus 로고
    • Lypermanie avec stupeur; Tendence a la demence-traitment par l'extract de cannabis sativa
    • J.J. Moreau de Tours Lypermanie avec stupeur; tendence a la demence-traitment par l'extract de cannabis sativa Lancette Gazette Hopital 30 1857 391
    • (1857) Lancette Gazette Hopital , vol.30 , pp. 391
    • Moreau De Tours, J.J.1
  • 262
    • 35649018143 scopus 로고    scopus 로고
    • Enhancement of endocannabinoid signaling and the pharmacotherapy of depression
    • DOI 10.1016/j.phrs.2007.09.003, PII S1043661807001624, The endocannabinoid system and psychopathology
    • R.A. Mangieri, and D. Piomelli Enhancement of endocannabinoid signaling and the pharmacotherapy of depression Pharmacol Res 56 2007 360 366 (Pubitemid 350026393)
    • (2007) Pharmacological Research , vol.56 , Issue.5 , pp. 360-366
    • Mangieri, R.A.1    Piomelli, D.2
  • 263
    • 26044433145 scopus 로고    scopus 로고
    • Is there a role for the endocannabinoid system in the etiology and treatment of melancholic depression?
    • DOI 10.1097/00008877-200509000-00006, Behavioural Pharmacology of Cannabinoids
    • M.N. Hill, and B.B. Gorzalka Is there a role for the endocannabinoid system in the etiology and treatment of melancholic depression? Behav Pharmacol 16 2005 333 352 (Pubitemid 41404805)
    • (2005) Behavioural Pharmacology , vol.16 , Issue.5-6 , pp. 333-352
    • Hill, M.N.1    Gorzalka, B.B.2
  • 266
    • 27844463517 scopus 로고    scopus 로고
    • Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
    • DOI 10.1056/NEJMoa044537
    • J.P. Despres, A. Golay, and L. Sjostrom Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia N Engl J Med 353 2005 2121 2134 (Pubitemid 41653104)
    • (2005) New England Journal of Medicine , vol.353 , Issue.20 , pp. 2121-2134
    • Despres, J.-P.1    Golay, A.2    Sjostrom, L.3
  • 268
    • 0037141754 scopus 로고    scopus 로고
    • Antagonist-induced μ-opioid receptor up-regulation decreases G-protein receptor kinase-2 and dynamin-2 abundance in mouse spinal cord
    • DOI 10.1016/S0014-2999(02)01823-X, PII S001429990201823X
    • M. Patel, B. Gomes, C. Patel, and B.C. Yoburn Antagonist-induced micro-opioid receptor up-regulation decreases G-protein receptor kinase-2 and dynamin-2 abundance in mouse spinal cord Eur J Pharmacol 446 2002 37 42 (Pubitemid 34722555)
    • (2002) European Journal of Pharmacology , vol.446 , Issue.1-3 , pp. 37-42
    • Patel, M.1    Gomes, B.2    Patel, C.3    Yoburn, B.C.4
  • 269
    • 70449376943 scopus 로고    scopus 로고
    • Cytokines and glucocorticoid receptor signaling. Relevance to major depression
    • T.W. Pace, and A.H. Miller Cytokines and glucocorticoid receptor signaling. Relevance to major depression Ann NY Acad Sci 1179 2009 86 105
    • (2009) Ann NY Acad Sci , vol.1179 , pp. 86-105
    • Pace, T.W.1    Miller, A.H.2
  • 271
    • 35948976128 scopus 로고    scopus 로고
    • Inhibition of human hair follicle growth by endoand exocannabinoids
    • DOI 10.1096/fj.06-7689com
    • A. Telek, T. Biro, E. Bodo, B.I. Toth, I. Borbiro, and G. Kunos Inhibition of human hair follicle growth by endo- and exocannabinoids FASEB J 21 2007 3534 3541 (Pubitemid 350075143)
    • (2007) FASEB Journal , vol.21 , Issue.13 , pp. 3534-3541
    • Telek, A.1    Biro, T.2    Bodo, E.3    Toth, B.I.4    Borbiro, I.5    Kunos, G.6    Paus, R.7
  • 272
    • 54049126951 scopus 로고    scopus 로고
    • Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling
    • N. Dobrosi, B.I. Toth, G. Nagy, A. Dozsa, T. Geczy, and L. Nagy Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling FASEB J 22 2008 3685 3695
    • (2008) FASEB J , vol.22 , pp. 3685-3695
    • Dobrosi, N.1    Toth, B.I.2    Nagy, G.3    Dozsa, A.4    Geczy, T.5    Nagy, L.6
  • 276
    • 20044386244 scopus 로고    scopus 로고
    • Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin
    • DOI 10.1016/j.jdermsci.2005.01.007, PII S0923181105000289
    • 2) on sensory nerve fibers and adnexal structures in human skin J Dermatol Sci 38 2005 177 188 (Pubitemid 40779571)
    • (2005) Journal of Dermatological Science , vol.38 , Issue.3 , pp. 177-188
    • Stander, S.1    Schmelz, M.2    Metze, D.3    Luger, T.4    Rukwied, R.5
  • 278
    • 25444464434 scopus 로고    scopus 로고
    • 2 receptor inverse agonist, JTE-907, in cutaneous inflammation in mice
    • DOI 10.1016/j.ejphar.2005.08.013, PII S0014299905008010
    • Y. Ueda, N. Miyagawa, T. Matsui, T. Kaya, and H. Iwamura Involvement of cannabinoid CB(2) receptor-mediated response and efficacy of cannabinoid CB(2) receptor inverse agonist, JTE-907, in cutaneous inflammation in mice Eur J Pharmacol 520 2005 164 171 (Pubitemid 41375825)
    • (2005) European Journal of Pharmacology , vol.520 , Issue.1-3 , pp. 164-171
    • Ueda, Y.1    Miyagawa, N.2    Matsui, T.3    Kaya, T.4    Iwamura, H.5
  • 279
    • 76249095734 scopus 로고    scopus 로고
    • Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cells
    • E. Kozela, M. Pietr, A. Juknat, N. Rimmerman, R. Levy, and Z. Vogel Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cells J Biol Chem 285 2010 1616 1626
    • (2010) J Biol Chem , vol.285 , pp. 1616-1626
    • Kozela, E.1    Pietr, M.2    Juknat, A.3    Rimmerman, N.4    Levy, R.5    Vogel, Z.6
  • 280
    • 79952191254 scopus 로고    scopus 로고
    • Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: Role of CB(1)/CB(2) receptors
    • in press
    • Braun A, Engel T, Aguilar-Pimentel JA, Zimmer A, Jakob T, Behrendt H, et al. Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: role of CB(1)/CB(2) receptors. Immunobiology, in press. doi:10.1016/j.imbio.2010.09.004.
    • Immunobiology
    • Braun, A.1    Engel, T.2    Aguilar-Pimentel, J.A.3    Zimmer, A.4    Jakob, T.5    Behrendt, H.6
  • 281
    • 0037379995 scopus 로고    scopus 로고
    • Attenuation of the ovalbumin-induced allergic airway response by cannabinoid treatment in A/J mice
    • DOI 10.1016/S0041-008X(03)00010-3
    • T.R. Jan, A.K. Farraj, J.R. Harkema, and N.E. Kaminski Attenuation of the ovalbumin-induced allergic airway response by cannabinoid treatment in A/J mice Toxicol Appl Pharmacol 188 2003 24 35 (Pubitemid 36369386)
    • (2003) Toxicology and Applied Pharmacology , vol.188 , Issue.1 , pp. 24-35
    • Jan, T.-R.1    Farraj, A.K.2    Harkema, J.R.3    Kaminski, N.E.4
  • 282
    • 42349104678 scopus 로고    scopus 로고
    • Cannabinomimetic control of mast cell mediator release: New perspective in chronic inflammation
    • DOI 10.1111/j.1365-2826.2008.01674.x
    • D. De Filippis, A. D'Amico, and T. Iuvone Cannabinomimetic control of mast cell mediator release: new perspective in chronic inflammation J Neuroendocrinol 20 Suppl. 1 2008 20 25 (Pubitemid 351552672)
    • (2008) Journal of Neuroendocrinology , vol.20 , Issue.SUPPL. 1 , pp. 20-25
    • De Filippis, D.1    D'Amico, A.2    Iuvone, T.3
  • 283
    • 77957342606 scopus 로고    scopus 로고
    • Expression and function of cannabinoid receptors in mouse islets
    • C. Li, J.E. Bowe, P.M. Jones, and S.J. Persaud Expression and function of cannabinoid receptors in mouse islets Islets 2 2010 293 302
    • (2010) Islets , vol.2 , pp. 293-302
    • Li, C.1    Bowe, J.E.2    Jones, P.M.3    Persaud, S.J.4
  • 284
    • 78049341843 scopus 로고    scopus 로고
    • Cannabinoid receptors are coupled to stimulation of insulin secretion from mouse MIN6 beta-cells
    • C. Li, P.M. Jones, and S.J. Persaud Cannabinoid receptors are coupled to stimulation of insulin secretion from mouse MIN6 beta-cells Cell Physiol Biochem 26 2010 187 196
    • (2010) Cell Physiol Biochem , vol.26 , pp. 187-196
    • Li, C.1    Jones, P.M.2    Persaud, S.J.3
  • 285
    • 77952635291 scopus 로고    scopus 로고
    • Phytocannabinoids beyond the Cannabis plant - Do they exist?
    • J. Gertsch, R.G. Pertwee, and V. Di Marzo Phytocannabinoids beyond the Cannabis plant - do they exist? Br J Pharmacol 160 2010 523 529
    • (2010) Br J Pharmacol , vol.160 , pp. 523-529
    • Gertsch, J.1    Pertwee, R.G.2    Di Marzo, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.