Upregulation of CB1 receptors and agonist-stimulated [ 35S]GTPγS binding in the prefrontal cortex of depressed suicide victims

Molecular Psychiatry

Volumn 9, Issue 2, 2004, Pages 184-190

  Hungund, B L ^a,b,c   Vinod, K Y ^b   Kassir, S A ^a   Basavarajappa, B S ^a,b   Yalamanchili, R ^b   Cooper, T B ^a,b,c   Mann, J J ^a,c   Arango, V ^a,c  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^c New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

35S GTP S binding; CB1 receptor; Depression; Prefrontal cortex; Suicide

Indexed keywords

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; CANNABINOID 1 RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); SULFUR 35; ANALGESIC AGENT; CYCLOHEXANOL DERIVATIVE; DIAGNOSTIC AGENT; SULFUR; TRITIUM;

ADOLESCENT; ADULT; AGED; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG TARGETING; FEMALE; HUMAN; HUMAN TISSUE; MAJOR DEPRESSION; MALE; NEUROPATHOLOGY; PREFRONTAL CORTEX; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION; SUICIDE ATTEMPT; UPREGULATION; WESTERN BLOTTING; DEPRESSION; DRUG POTENTIATION; METABOLISM; MIDDLE AGED; SUICIDE;

ADOLESCENT; ADULT; AGED; ANALGESICS; CYCLOHEXANOLS; DEPRESSIVE DISORDER; FEMALE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; MALE; MIDDLE AGED; PREFRONTAL CORTEX; RECEPTOR, CANNABINOID, CB1; SUICIDE; SULFUR RADIOISOTOPES; TRITIUM; UP-REGULATION;

EID: 1542344972     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001376     Document Type: Article

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