Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: Involvement of cytokine/chemokines and PMN

Journal of Leukocyte Biology

Volumn 75, Issue 3, 2004, Pages 453-459

  Di Filippo, Clara ^a   Rossi, Francesco ^a   Rossi, Settimio ^a   D'Amico, Michele ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Heart infarct; IL 1 ; Leukocytes; WIN55212 2

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; ALPHA CHEMOKINE; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR AGONIST; CANNABINOID RECEPTOR ANTAGONIST; INTERLEUKIN 1BETA; MYELOPEROXIDASE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART HEMODYNAMICS; HEART INFARCTION SIZE; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEMODYNAMIC MONITORING; INHIBITION KINETICS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY;

ANIMALS; CHEMOKINES; CYTOKINES; INFLAMMATION; INTERLEUKIN-1; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; NEUTROPHILS; PEROXIDASE; PROTECTIVE AGENTS; RECEPTOR, CANNABINOID, CB2;

ANIMALIA;

EID: 1542283728     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0703303     Document Type: Article

References (46)

1. Ambrosio, G., Tritto, L. (1999) Reperfusion injury: experimental evidence and clinical implications. Am. Heart J. 138, S69-S75.
2. La, M., Tailor, A., D'Amico, M., Flower, R. J., Perretti, M. (2001) Analysis of the protection afforded by annexin 1 in ischaemia-reperfusion injury: focus on neutrophil recruitment. Eur. J. Pharmacol. 429, 263-278.
3. Hanus, L., Breuer, A., Tchilibon, S., Shioah, S., Goldenberg, D., Horowitz, M., Pertwee, R. G., Ross, R. A., Mechoulam, R., Fride, E. (1999) HU-308: a specific agonist for CB2, a peripheral cannabinoid receptor. Proc. Natl. Acad. Sci. USA 96, 14228-14233.
4. Smith, S. R., Terminelli, C., Denhardt, G. (2000) Effects of cannabinoid receptor agonist and antagonist ligands on the production of inflammatory cytokines and antiinflammatory IL-10. J. Pharmacol. Exp. Ther. 293, 136-150.
5. Beaulieu, P., Bisogno, T., Punwar, S., Farquhar-Smith, W. P., Ambrosio, G., Di Marzo, V., Rice, A. S. (2000) Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat. Eur. J. Pharmacol. 396, 85-92.
6. Clayton, N., Marshall, F. H., Bountra, C., O'Shaughnessy, C. T. (2002) CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain. Pain 96, 253-260.
7. Conti, S., Costa, B., Colleoni, M., Parolaro, D., Giagnoni, G. (2002) Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat. Br. J. Pharmacol. 135, 181-187.
8. Berdyshev, E., Boichot, E., Corbel, M., Germani, N., Lagente, V. (1998) Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice. Life Sci. 63, PL125-PL129.
9. Klein, T. W., Lane, B., Newton, C. A., Friedman, H. (2000) The cannabinoid system and cytokine network. Proc. Soc. Exp. Biol. Med. 225, 1-8.
10. Sacerdote, P., Massi, P., Panerai, A. E., Parolaro, D. (2000) In vivo and in vitro treatment with the synthetic cannabinoid CP55,940 decreases the in vitro migration of macrophages in the rat: involvement of both CB1 and CB2 receptors. J. Neuroimmunol. 109, 155-163.
11. Sànchez, C., de Ceballos, M. L., Gòmez del Pulgar, T. G., Rueda, D., Corbacho, C., Velasco, G., Galve-Roperh, I., Huffman, J. W., Ramon y Cajal, S., Guzmàn, M. (2001) Inhibition of glioma growth in vivo by selective activation of the CB2 cannabinoid receptor. Cancer Res. 61, 5784-5789.
12. Lagneux, C., Lamontagne, D. (2001) Involvement of cannabinoids in the cardioprotection induced by lipopolysaccharide. Br. J. Pharmacol. 132, 793-796.
13. Krylatov, A. V., Bernatsksaia, N. A., Maslov, L. N., Pertwee, R. G., Mechoulam, R., Stefano, G. B., Sharaevskii, M. A., Sal'nikova, O. M. (2002) Increase of the heart arrhythmogenic resistance and decrease of the myocardial necrosis zone during activation of cannabinoid receptors. Ross. Fiziol. Zh. Im. I. M. Sechenova. 88, 560-567.
14. Krylatov, A. V., Uzhachenko, R. V., Maslov, L. N., Ugdyzhekova, D. S., Bernatskaia, N. A., Pertwee, R. G., Stefano, G. B., Makriyannis, A. (2002) Anandamide and R-(+)-methanandamide prevent development of ischemic and reperfusion arrhythmia in rats by stimulation of CB2-receptors. Eksp. Klein Farmakol. 65, 6-9.
15. Joyeux, M., Arnaud, C., Godin-Ribout, D., Demenge, P., Lamontagne, D., Ribout, C. (2002) Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts. Cardiovasc. Res. 55, 619-625.
16. D'Amico, M., Di Filippo, C., La, M., Solito, E., McLean, P., Flower, R. J., Perretti, M. (2000) Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocytes recruitment. FASEB J. 14, 1867-1869.
17. Michael, L. H., Entman, M. L., Hartley, C. J., Youcher, K. A., Zhu, J., Hall, S. R., Hawkins, H. K., Berens, K., Ballantyne, C. M. (1995) Myocardial ischemia and reperfusion: a murine model. Am. J. Physiol. 269, H2147-H2154.
18. Smith, S. R., Terminelli, C., Denhardt, G. (2001a) Modulation of cytokine responses in Corynebacterium parvum primed mice by centrally administered cannabinoid ligands. Eur. J. Pharmacol. 425, 73-83.
19. Smith, S. R., Denhardt, G., Terminelli, C. (2001b) The anti-inflammatory activities of cannabinoid receptor ligands in mouse peritonitis models. Eur. J. Pharmacol. 432, 107-119.
20. Malan, T. P., Ibrahim, M. M., Deng, H., Liu, Q., Mata, H. P., Vanderah, T., Porreca, F., Makriyannis, A. (2001) CB2 cannabinoid receptor-mediated peripheral antinociception. Pain 93, 239-245.
21. Gardiner, S. M., March, J. E., Kemp, P. A., Bennett, T. (2002) Influence of the CB1 receptor antagonist, AM251, on the regional haemodynamic effects of WIN55212-2 or HU210 in conscious rats. Br. J. Pharmacol. 136, 581-587.
22. Mullane, K. M., Kraemer, R., Smith, B. (1985) Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J. Pharmacol. Methods 14, 157-167.
23. Ajuebor, M. N., Das, A. M., Virag, L., Flower, R. J., Szabo, C., Perretti, M. (1999) Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10. J. Immunol. 162, 1685-1691.
24. Baller, D., Bretschneider, H. J., Hellige, G. (1981) A critical look at currently used indices of myocardial oxygen consumption. Basic Res. Cardiol. 76, 163-181.
25. Adams, M. D., Earnhardt, J. T., Martin, B. R., Harris, L. S., Dewey, W. L., Razdan, R. K. (1977) A cannabionid with cardiovsascular activity but no overt behavioral effects. Experientia 33, 1204-1205.
26. Felder, C. C., Glass, M. (1998) Cannabinoid receptors and their endogenous agonists. Annu. Rev. Pharmacol. Toxicol. 38, 179-200.
27. Pertwee, R. G. (2000) Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development. Expert Opin. Investig. Drugs 9, 1553-1571.
28. Matsuda, L. A., Lolait, S. J., Brownstein, M., Young, A., Bonner, T. I. (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346, 561-564.
29. Munro, S., Thomas, K. L., Abu-Shaar, M. (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature 365, 61-65.
30. Straiker, A., Stella, N., Piomelli, D., Mackie, K., Karten, H. J., Maguire, G. (1999) Cannabinoid CB1 receptors and ligands in vertebrate retina: localization and function of an endogenous signalling system. Proc. Natl. Acad. Sci. USA 96, 14565-14570.
31. Galiegue, S., Mary, S., Marchand, J., Dussossoy, D., Carriere, D., Carayon, P., Bouaboula, M., Shire, D., Le Fur, G., Casellas, P. (1995) Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulation. Eur. J. Biochem. 232, 54-61.
32. Carlisle, S. J., Marciano-Cabral, F., Staab, A., Ludwick, C., Cabral, G. A. (2002) Differential expression of the CB2 cannabinoid receptors by rodent macrophages and macrophages-like cells in relation to cell activation. Int. Immunopharmacol. 2, 69-82.
33. Showalter, V. M., Compton, D. R., Martin, B. R., Abood, M. E. (1996) Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor sub-type selective ligands. J. Pharmacol. Exp. Ther. 278, 989-999.
34. Leker, R. R., Gai, N., Mechoulam, R., Ovadia, H. (2003) Drug-induced hypothermia reduces ischemic damage: effects of the cannabinoid HU-210. Stroke 34, 2000-2006.
35. Ajuebor, M. N., Swain, M. G., Perretti, M. (2002) Chemokines as novel therapeutic targets in inflammatory diseases. Biochem. Pharmacol. 63, 1191-1196.
36. Thorne, S. A., Abbot, S. E., Stevens, C. R., Winyard, P.G., Millis, P. G., Blake, D. R. (1996) Modified low density lipoprotein and cytokines-mediate monocyte adhesion to smooth muscle cells. Atherosclerosis 127, 167-176.
37. Lee, S., Felts, K. A., Parry, G. C., Armacost, L. M., Cobb, R. R. (1997) Inhibition of 5-lipoxygenase blocks IL-1β-induced vascular adhesion molecule-1 gene expression in human endothelial cells. J. Immunol. 158, 3401-3407.
38. Ajuebor, M. N., Virag, L., Flower, R. J., Perretti, M., Szabo, C. (1998) Role of inducible nitric oxide synthase in the regulation of neutrophil migration in zymosan-induced inflammation. Immunology 95, 625-630.
39. Tailor, A., Tomlinson, A., Salas, A., Panes, J., Granger, D. N., Flower, R. J., Perretti, M. (1999) Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC. Gut 45, 705-712.
40. Hwang, M. W., Matsumori, A., Furukawa, Y., Ono, K., Okada, M., Iwasaki, A., Hara, M., Miyamoto, T., Touma, M., Sasayama, S. (2001) Neutralization of interleukin-1β in the acute phase of myocardial infarction promotes the progression of left ventricular remodelling. J. Am. Coll. Cardiol. 38, 1546-1553.
41. Deten, A., Volz, H. C., Briest, W., Zimmer, H. G. (2002) Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats. Cardiovasc. Res. 55, 329-340.
42. Kamisnski, K. A., Bonda, T. A., Korecki, J., Musial, W. (2002) Oxidative stress and neutrophil activation - the two keystones of ischemia/reperfusion injury. Int. J. Cardiol. 86, 41-49.
43. Sayers, T. J., Wiltrout, T. A., Bull, C. A. (1988) Effect of cytokine on polymorphonuclear neutrophil infiltration in the mouse. Prostaglandin- and leukocyte-independent induction of infiltration by IL-1 and tumor necrosis factor. J. Immunol. 141, 1670-1677.
44. Klein, T. W., Lane, B., Newton, C. A., Friedman, H. (1998) Cannabinoid receptors and immunity. Immunol. Today 19, 373-381.
45. Cabral, G. A., Dove-Petit, D. A. (1998) Drugs and immunità: cannabinoids and their role in decreased resistance to infectious disease. J. Neuroimmunol. 83, 116-123.
46. Omata, M., Matsui, N., Inomata, N., Ohno, T. (1997) Protective effects of polysaccharide fucoidin on myocardial ischemia-reperfusion injury in rats. J. Cardiovasc. Pharmacol. 30, 717-724.