Modulation of the balance between cannabinoid CB1 and CB2 receptor activation during cerebral ischemic/reperfusion injury

Neuroscience

Volumn 152, Issue 3, 2008, Pages 753-760

  Zhang, M ^a   Martin, B R ^b   Adler, M W ^a   Razdan, R K ^c   Ganea, D ^a   Tuma, R F ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ORGANIX INC   (United States)

Author keywords

cerebral blood flow; cerebral ischemia reperfusion injury; endogenous cannabinoids; inflammatory responses

Indexed keywords

5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR AGONIST; O 1966; RIMONABANT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG EFFECT; LOW DRUG DOSE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY;

ANIMALS; BRAIN ISCHEMIA; CANNABINOIDS; CEREBRAL CORTEX; CEREBRAL INFARCTION; DRUG COMBINATIONS; DRUG SYNERGISM; ENDOCANNABINOIDS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2; REPERFUSION INJURY; RNA, MESSENGER; TIME FACTORS; TREATMENT OUTCOME;

EID: 40949116660     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.01.022     Document Type: Article

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