Production and physiological actions of anandamide in the vasculature of the rat kidney

Journal of Clinical Investigation

Volumn 100, Issue 6, 1997, Pages 1538-1546

  Deutsch, Dale G ^a   Goligorsky, Michael S ^a   Schmid, Patricia C ^b   Krebsbach, Randy J ^b   Schmid, Harald H O ^b   Das, S K ^c   Dey, S K ^c   Arreaza, G ^a   Thorup, Christian ^a   Stefano, George ^d   Moore, Leon C ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^d STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Afferent; Anandamide amidase; Cannabinoids; Endothelial cells; Nitric oxide

Indexed keywords

ANANDAMIDE; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR AGONIST; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NORADRENALIN; RIMONABANT;

ANIMAL CELL; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; ENDOTHELIUM CELL; KIDNEY BLOOD FLOW; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 0030798335     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119677     Document Type: Article

References (55)

1. Evans, F.J. 1991. Cannabinoids: the separation of central from peripheral effects on a structural basis. Planta Med. 57(Suppl. 1)60-67.
2. Matsuda, L.A., S.J. Lolait, M.J. Brownstein, A.C. Young, and T.I. Bonner. 1990. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature (Lond.). 346:561-564.
3. Munro, S., K.L. Thomas, and M. Abu-Shaar. 1993. Molecular characterization of a peripheral receptor for cannabinoid. Nature (Lond.). 365:61-65.
4. Devane, W.A., L. Hanus, A. Breuer, R.G. Pertwee, L.A. Stevenson, G. Griffin, D. Gibson, A. Mandelbaum, A. Etinger, and R. Mechoulam. 1992. Isolation and structure of a brain constituent that hinds to the cannabinoid receptor. Science (Wash. DC). 258:1946-1949.
5. Schmid, P.C., R.J. Krebsbach, S.R. Perry, T.M. Dettmer, J.L. Maasson, and H.H. Schmid. 1995. Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain. FEBS Lett. 375 (Corrigendum 385:125-126, 1996):117-120.
6. Kempe, K., F.F. Hsu, A. Bohrer, and J. Turk. 1996. Isotope dilution mass spectrometric measurements indicate that arachidonylethanolamide, the proposed endogenous ligand of the cannabinoid receptor, accumulates in rat brain tissue post mortem but is contained at low levels in or is absent from fresh tissue. J. Biol. Chem. 271:17287-17295.
7. Felder, C.C., A. Nielsen, E.M. Briley, M. Palkovit, J. Priller, J. Axelrod, D.N. Nguyen, J.M. Richardson, R.M. Riggins, G.A. Koppel, et al. 1996. Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and ral. FEBS Lett. 393:231-235.
8. Schmid, P.C., B.C. Paria, R.J. Krebsbach, H.H.O. Schmid, and S.K. Dey. 1997. Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. Proc. Natl. Acad. Sci. USA. 94:4188-4192.
9. 2+-dependent transacylase and phosphodiesterase activities. Biochem. Biophys. Res. Commun. 218:113-117.
10. Howlett, A.C., M. Bidaut-Russell, W.A. Devane, L.S. Melvin, M.R. Johnson, and M. Herkenham. 1990. The cannabinoid receptor: biochemical, anatomical and behavioral characterization. Trends Neurosci. 13:420-423.
11. Nah, S.Y., D. Saya, and Z. Vogel. 1993. Cannabinoids inhibit agonist-stimulated formation of inositol phosphates in rat hippocampal cultures. Eur. J. Pharmacol. 246:19-24.
12. Mackie, K., and B. Hille. 1992. Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc. Natl. Acad. Sci. USA. 89:3825-3829.
13. Venance, L., D. Piomelli, J. Glowinski, and C. Giaume. 1495. Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes. Nature (Lond.). 376:590-594.
14. Ellis, E.F., S.F. Moore, and K.A. Willoughby. 1995. Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin. Am. J. Physiol. 269:H1859-H1864.
15. Shen, M., T.M. Piser, V.S. Seybold, and S.A. Thayer. 1996. Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures. J. Neurosci. 16:4322-4334.
16. Van der Kloot, W. 1994. Anandamide, a naturally-occurring agonist of the cannabinoid receptor, blocks adenylate cyclase at the frog neuromuscular junction. Brain Res. 649:181-184.
17. Deutsch, D.G., and S.A. Chin. 1993. Enzymatic synthesis and degradation of anandamide, a cannahinoid receptor agonist. Biochem. Pharmacol. 46: 791-796.
18. Shire, D., C. Carillon, M. Kaghad, B. Calandra, M. Rinaldi-Carmona, G. Le Fur, D. Caput, and P. Ferrara. 1995. An amino-tcrminal variant of the central cannabinoid receptor resulting from alternative splicing. J. Biol. Chem. 270: 3726-3731.
19. Folch, J., M. Lees, and G.H. Sloane-Stanley. 1957. A simple method for the isolation and purification of total lipides from animal tissue. J. Biol. Chem. 226:497-507.
20. Iijima, K., L.C. Moore, and M.S. Goligorsky. 1991. Syncytial organization of cultured rat mesangial cells. Am. J. Physiol. 260:F848-F855.
21. Tsukahara, H., D.V. Gordienko, B. Tonshoff, M.C. Gelato, and M.S. Goligorsky. 1994. Direct demonstration of insulin-like growth factor-I-induced nitric oxide production by endothelial cells. Kidney Int. 45:598-604.
22. Schmid, P.C., V. Natarajan, B.K. Weis, and H.H. Schmid. 1986. Hydrolysis of N-acylated glycerophospholipids by phospholipases A2 and D: a method of identification and analysis. Chem. Phys. Lipids. 41:195-207.
23. Das, S.K., B.C. Paria, I. Chakraborty, and S.K. Dey. 1995. Cannabinoid ligand-receptor signaling in the mouse uterus. Proc. Natl. Acad. Sci. USA. 92: 4332-4336.
24. Paria, B.C., S.K. Das, G.K. Andrews, and S.K. Dey. 1993. Expression of the epidermal growth factor receptor gene is regulated in mouse blastocysts during delayed implantation. Proc. Natl. Acad. Sci. USA. 90:55-59.
25. Omeir, R.L., S. Chin, Y. Hong, D.G. Ahern, and D.G. Deutsch. 1995. Arachidonoyl ethanolamide-[1,2-14C] as a substrate for anandamide amidase. Life Sci. 56:1999-2005.
26. Casellas, D., and L.G. Navar. 1984. In vitro perfusion of juxtamedullary nephrons in rats. Am. J. Physiol. 246:F349-F358.
27. Casellas, D., and L.C. Moore. 1990. Autoregulation and tubuloglomerular feedback in juxtamedullary glomerular arterioles. Am. J. Physiol. 258:F660-F669.
28. Stefano, G.B., B. Hall, M.H. Makman, and B. Dvorkin. 1981. Opioids inhibit potassium-stimulated dopamine release in the marine mussel Mytilus edulis and in the cephalopod. Octopus himaculatus. Science (Wash. DC). 213: 928-930.
29. Schmid, P.C., P.V. Reddy, V. Natarajan, and H.H.O. Schmid. 1983. Metabolism of N-acylethanolamine phospholipids by a mammalian phosphodiesterase of the phospholipase D type. J. Biol. Chem. 258:9302-9306.
30. Ueda, N., Y. Kurahashi, S. Yamamoto, and T. Tokunaga. 1995. Partial purification and characterization of the porcine brain enzyme hydrolyzing and synthesizing anandamide. J. Biol. Chem. 270:23823-23827.
31. Schmid, P.C., M.L. Zuzarte-Augustin, and H.H. Schmid. 1985. Properties of rat liver N-acylethanolamine amidohydrolase. J. Biol. Chem. 260:14145-14149.
32. Rinaldi-Carmona, M., F. Barth, M. Heaulme, D. Shire, B. Calandra, C. Congy, S. Martinez, J. Maruani, G. Neliat, D. Caput. et al. 1994. SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett. 350:240-244.
33. Mechoulam, R., L. Hanus, and B.R. Martin. 1994. Search for endogenous ligands of the cannabinoid receptor. Biochem. Pharmacol. 48:1537-1544.
34. Di Marzo, V., L. De Petrocellis, T. Bisogno, and S. Maurelli. 1995. Pharmacology and physiology of the endogenous cannabimimetic mediator anandamide. J. Drug Dev. Clin. Pract. 7:199-219.
35. Schmid, H.H., P.C. Schmid, and V. Natarajan. 1990. N-acylated glycerophospholipids and their derivatives. Prog. Lipid Res. 29:1-43.
36. Schmid, H.H., P.C. Schmid, and V. Natarajan. 1996. The N-acylation-phosphodiesterase pathway and cell signaling. Chem. Phys. Lipids. 80:133-142.
37. Kruszka, K.K., and R.W. Gross. 1994. The ATP- and CoA-independent synthesis of arachidonoylethanolamide. A novel mechanism underlying the synthesis of the endogenous ligand of the cannabinoid receptor. J. Biol. Chem. 269:14345-14348.
38. Devane, W.A., and J. Axelrod. 1994. Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. Proc. Natl. Acad. Sci. USA. 91:6698-6701.
39. Desarnaud, F., H. Cadas, and D. Piomelli. 1995. Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization. J. Biol. Chem. 270:6030-6035.
40. Sugiura, T., S. Kondo, A. Sukagawa, S. Nakane, A. Yamashita, Y. Ishima, and K. Waku. 1996. Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, and endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine. Eur. J. Biochem. 240:43-62.
41. Paria, B.C., D.G. Deutsch, and S.K. Dey. 1996. The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the preimplantation period. Mol. Reprod. Dev. 45:183-192.
42. Galiegue, S., S. Mary, J. Marchand, D. Dussossoy, D. Carriere, P. Carayon, M. Bouaboula, D. Shire, G. Le Fur, and P. Casellas. 1995. Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations. Eur. J. Biochem. 232:54-61.
43. Lake, K.D., B.R. Martin, G. Kunos, and K. Varga. 1997. Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. Hypertension (Dallas). 29:1204-1210.
44. Graham, J.P.D. 1986. The cardiovascular actions of cannabinoids. In Cannabinoids as Therapeutic Agents. R. Mechoulam, editor. CRC Press Inc., Boca Raton, FL.
45. Pertwee, R.G., S.R. Fernando, G. Griffin, V. Abadji, and A. Makriyannis. 1995. Effect of phenylmethylsulphonyl fluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations. Eur. J. Pharmacol. 272:73-78.
46. Schwarz, P., R. Diem, N.J. Dun, and U. Forstermann. 1995. Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves. Circ. Res. 77:841-848.
47. Egi, Y., Y. Matsumura, S. Murata, T. Umekawa, K. Hisaki, M. Takaoka, and S. Morimoto. 1994. The effects of NG-nitro-L-arginine, a nitric oxide synthase inhibitor, on norepinephrine overflow and antidiuresis induced by stimulation of renal nerves in anesthetized dogs. J. Pharmacol. Exp. Therap. 269:529-535.
48. Stefano, G.B., B. Scharrer, E.M. Smith, T.K. Hughes, H.I. Magazine, T.V. Bilfinger, A.R. Hartman, G.L. Fricchione, Y. Liu, and M.H. Makman. 1996. Opioid and opiate immunoregulatory processes. Crit. Rev. Immunol. 16: 109-144.
49. Matsuoka, H., H. Nishida, G. Nomura, B.N. Van Vliet, and H. Toshima. 1994. Hypertension induced by nitric oxide synthesis inhibition is renal nerve dependent. Hypertension (Dallas). 23:971-975.
50. Randall, M.D., S.P.H. Alexander, T. Bennett, E.A. Boyd, J.R. Fry, S.M. Gardiner, P.A. Kemp, A.I. McCulloch, and D.A. Kendall. 1996. An endogenous cannabinoid as endothelium-derived vasorelaxant. Biochem. Biophys. Res. Comm. 229:114-120.
51. Wagner, A.J., N.-H. Holstein-Rathlou, and D.J. Marsh. 1997. Internephron coupling by conducted vasomotor responses in normotensive and spontaneously hypertensive rats. Am. J. Physiol. 272 (Renal Physiol. 41):F372-F379.
52. Chang, M.C., D. Berkery, R. Schuel, S.G. Laychock, A.M. Zimmerman, S. Zimmerman, and H. Schuel. 1993. Evidence for a cannabinoid receptor in sea urchin sperm and its role in blockade of the acrosome reaction. Mol. Reprod. Dev. 36:507-516.
53. Schuel, H., E. Goldstein, R. Mechoulam, A.M. Zimmerman, and S. Zimmerman. 1994. Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. Proc. Natl. Acad. Sci. USA. 91:7678-7682.
54. Stefano, G.B., B. Salzet, and M. Salzet. 1997. Identification and characterization of the leech CNS cannabinoid receptor: coupling to nitric oxide release. Brain Res. In press.
55. Stefano, G.B., Y. Liu, and M.S. Goligorsky. 1996. Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia. and human monocytes. J. Biol. Chem. 271:19238-19242.