Selective CB2 receptor agonism protects central neurons from remote axotomy-induced apoptosis through the PI3K/Akt pathway

Journal of Neuroscience

Volumn 29, Issue 14, 2009, Pages 4564-4570

  Viscomi, Maria Teresa ^a,b   Oddi, Sergio ^a,c   Latini, Laura ^a,b   Pasquariello, Nicoletta ^c   Florenzano, Fulvio ^a   Bernardi, Giorgio ^a,d   Molinari, Marco ^a,b   Maccarrone, Mauro ^a,c  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b Spinal Trauma and Disease Foundation Onlus   (Italy)

^c UNIVERSITY OF TERAMO   (Italy)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 3 (1 NAPHTHOYL) 1 PROPYLINDOLE; 2 MORPHOLINO 8 PHENYLCHROMONE; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CELL LOSS; CELL PROTECTION; CELL SURVIVAL; CEREBELLUM INJURY; CONTROLLED STUDY; HEMISPHERE; NERVE CELL; NERVE FIBER DEGENERATION; NERVE FIBER TRANSECTION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; AXOTOMY; CELL SURVIVAL; CEREBELLUM; INDOLES; MALE; NEURONS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RECEPTOR, CANNABINOID, CB2; SIGNAL TRANSDUCTION;

EID: 65549125084     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0786-09.2009     Document Type: Article

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