메뉴 건너뛰기




Volumn 134, Issue 2, 2008, Pages 622-625

Endocannabinoids, CB1 Receptors, and Liver Disease: Hitting More Than One Bird With the Same Stone

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABIS; ENDOCANNABINOID;

EID: 38649116306     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2007.12.017     Document Type: Editorial
Times cited : (9)

References (30)
  • 1
    • 33748703859 scopus 로고    scopus 로고
    • The endocannabinoid system as an emerging target for pharmacotherapy
    • Pacher P., Bátkai S., and Kunos G. The endocannabinoid system as an emerging target for pharmacotherapy. Pharmacol Rev 58 (2006) 389-462
    • (2006) Pharmacol Rev , vol.58 , pp. 389-462
    • Pacher, P.1    Bátkai, S.2    Kunos, G.3
  • 2
    • 0034928628 scopus 로고    scopus 로고
    • Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis
    • Bátkai S., Járai Z., Wagner J.A., et al. Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. Nat Med 7 (2001) 827-832
    • (2001) Nat Med , vol.7 , pp. 827-832
    • Bátkai, S.1    Járai, Z.2    Wagner, J.A.3
  • 3
    • 34548444632 scopus 로고    scopus 로고
    • Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats
    • Bátkai S., Mukhopadhyay P., Harvey-White J., et al. Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. Am J Physiol Heart Circ Physiol 293 (2007) H1689-H1695
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Bátkai, S.1    Mukhopadhyay, P.2    Harvey-White, J.3
  • 4
    • 27144472559 scopus 로고    scopus 로고
    • Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats
    • Gaskari S.A., Liu H., Moezi L., et al. Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats. Br J Pharmacol 146 (2005) 315-323
    • (2005) Br J Pharmacol , vol.146 , pp. 315-323
    • Gaskari, S.A.1    Liu, H.2    Moezi, L.3
  • 5
    • 0036142225 scopus 로고    scopus 로고
    • Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat
    • Ros J., Clària J., To-Figueras J., et al. Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat. Gastroenterology 122 (2002) 85-93
    • (2002) Gastroenterology , vol.122 , pp. 85-93
    • Ros, J.1    Clària, J.2    To-Figueras, J.3
  • 6
    • 15744388722 scopus 로고    scopus 로고
    • Antifibrogenic role of the cannabinoid receptor CB2 in the liver
    • Julien B., Grenard P., Teixeira-Clerc F., et al. Antifibrogenic role of the cannabinoid receptor CB2 in the liver. Gastroenterology 128 (2005) 742-755
    • (2005) Gastroenterology , vol.128 , pp. 742-755
    • Julien, B.1    Grenard, P.2    Teixeira-Clerc, F.3
  • 7
    • 33745003240 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis
    • Teixeira-Clerc F., Julien B., Grenard P., et al. CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis. Nat Med 12 (2006) 672-676
    • (2006) Nat Med , vol.12 , pp. 672-676
    • Teixeira-Clerc, F.1    Julien, B.2    Grenard, P.3
  • 8
    • 34547423962 scopus 로고    scopus 로고
    • Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats
    • Gary-Bobo M., Elachouri G., et al. Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats. Hepatology 46 (2007) 122-129
    • (2007) Hepatology , vol.46 , pp. 122-129
    • Gary-Bobo, M.1    Elachouri, G.2
  • 9
    • 20944436157 scopus 로고    scopus 로고
    • Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
    • Osei-Hyiaman D., DePetrillo M., Pacher P., et al. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest 115 (2005) 1298-1305
    • (2005) J Clin Invest , vol.115 , pp. 1298-1305
    • Osei-Hyiaman, D.1    DePetrillo, M.2    Pacher, P.3
  • 10
    • 38649114788 scopus 로고    scopus 로고
    • Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver
    • (in press)
    • Jeong W.I., Osei-Hyiaman D., Park O., et al. Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell Metab 7 (2008) (in press)
    • (2008) Cell Metab , vol.7
    • Jeong, W.I.1    Osei-Hyiaman, D.2    Park, O.3
  • 11
    • 21344472982 scopus 로고    scopus 로고
    • Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C
    • Hézode C., Roudot-Thoraval F., Nguyen S., et al. Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C. Hepatology 42 (2005) 63-71
    • (2005) Hepatology , vol.42 , pp. 63-71
    • Hézode, C.1    Roudot-Thoraval, F.2    Nguyen, S.3
  • 12
    • 38649131428 scopus 로고    scopus 로고
    • Daily cannabis use: a novel risk factor of steatosis severity in patients with chronic hepatitis C
    • Hézode C., Zafrani E.S., Roudot-Thoraval F., et al. Daily cannabis use: a novel risk factor of steatosis severity in patients with chronic hepatitis C. Gastroenterology 134 (2008) 432-439
    • (2008) Gastroenterology , vol.134 , pp. 432-439
    • Hézode, C.1    Zafrani, E.S.2    Roudot-Thoraval, F.3
  • 13
    • 1842866963 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
    • Ravinet Trillou C., Delgorge C., Menet C., et al. CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity. Int J Obes Relat Metab Disord 28 (2004) 640-648
    • (2004) Int J Obes Relat Metab Disord , vol.28 , pp. 640-648
    • Ravinet Trillou, C.1    Delgorge, C.2    Menet, C.3
  • 14
    • 27844463517 scopus 로고    scopus 로고
    • Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
    • Rimonabant in Obesity-Lipids Study Group
    • Després J.P., Golay A., Sjöström L., and Rimonabant in Obesity-Lipids Study Group. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N Engl J Med 353 (2005) 2121-2134
    • (2005) N Engl J Med , vol.353 , pp. 2121-2134
    • Després, J.P.1    Golay, A.2    Sjöström, L.3
  • 15
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial
    • RIO-North America Study Group
    • Pi-Sunyer F.X., Aronne L.J., Heshmati H.M., et al., RIO-North America Study Group. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA 295 (2006) 761-775
    • (2006) JAMA , vol.295 , pp. 761-775
    • Pi-Sunyer, F.X.1    Aronne, L.J.2    Heshmati, H.M.3
  • 16
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
    • RIO-Europe Study Group
    • Van Gaal L.F., Rissanen A.M., Scheen A.J., et al., RIO-Europe Study Group. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 365 (2005) 1389-1397
    • (2005) Lancet , vol.365 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3
  • 17
    • 32044464960 scopus 로고    scopus 로고
    • Activation of cannabinoid CB1 receptors induces glucose intolerance in rats
    • Bermúdez-Siva F.J., Serrano A., Diaz-Molina F.J., et al. Activation of cannabinoid CB1 receptors induces glucose intolerance in rats. Eur J Pharmacol 531 (2006) 282-284
    • (2006) Eur J Pharmacol , vol.531 , pp. 282-284
    • Bermúdez-Siva, F.J.1    Serrano, A.2    Diaz-Molina, F.J.3
  • 18
    • 13244249625 scopus 로고    scopus 로고
    • Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice
    • Liu Y.L., Connoley I.P., Wilson C.A., et al. Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice. Int J Obes (Lond) 29 (2005) 183-187
    • (2005) Int J Obes (Lond) , vol.29 , pp. 183-187
    • Liu, Y.L.1    Connoley, I.P.2    Wilson, C.A.3
  • 19
    • 12744260206 scopus 로고    scopus 로고
    • The anti-obesity effect of rimonabant is associated with an improved serum lipid profile
    • Poirier B., Bidouard J.P., Cadrouvele C., et al. The anti-obesity effect of rimonabant is associated with an improved serum lipid profile. Diabetes Obes Metab 7 (2005) 65-72
    • (2005) Diabetes Obes Metab , vol.7 , pp. 65-72
    • Poirier, B.1    Bidouard, J.P.2    Cadrouvele, C.3
  • 20
  • 21
    • 33751001942 scopus 로고    scopus 로고
    • Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study
    • RIO-Diabetes Study Group
    • Scheen A.J., Finer N., Hollander P., et al., RIO-Diabetes Study Group. Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study. Lancet 368 (2006) 1660-1672
    • (2006) Lancet , vol.368 , pp. 1660-1672
    • Scheen, A.J.1    Finer, N.2    Hollander, P.3
  • 22
    • 0023155534 scopus 로고
    • Hepatic triacylglycerol accumulation induced by ethanol and carbon tetrachloride: interactions with essential fatty acids and prostaglandins
    • Cunnane S.C. Hepatic triacylglycerol accumulation induced by ethanol and carbon tetrachloride: interactions with essential fatty acids and prostaglandins. Alc Clin Exp Res 11 (1987) 25-30
    • (1987) Alc Clin Exp Res , vol.11 , pp. 25-30
    • Cunnane, S.C.1
  • 23
    • 16844378302 scopus 로고    scopus 로고
    • Hepatitis C virus-induced hepatocellular steatosis
    • Castera L., Chouteau P., Hézode C., et al. Hepatitis C virus-induced hepatocellular steatosis. Am J Gastroenterol 100 (2005) 711-715
    • (2005) Am J Gastroenterol , vol.100 , pp. 711-715
    • Castera, L.1    Chouteau, P.2    Hézode, C.3
  • 24
    • 0028108372 scopus 로고
    • Inactivation of Kupffer cells prevents early alcohol-induced liver injury
    • Adachi Y., Bradford B., Gao W., et al. Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 20 (1994) 453-460
    • (1994) Hepatology , vol.20 , pp. 453-460
    • Adachi, Y.1    Bradford, B.2    Gao, W.3
  • 25
    • 13744255589 scopus 로고    scopus 로고
    • Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
    • Duffield J.S., Forbes S.J., Constandinou C.M., et al. Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Invest 115 (2005) 56-65
    • (2005) J Clin Invest , vol.115 , pp. 56-65
    • Duffield, J.S.1    Forbes, S.J.2    Constandinou, C.M.3
  • 26
    • 0242497230 scopus 로고    scopus 로고
    • Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor
    • Liu J., Batkai S., Pacher P., et al. Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor. J Biol Chem 278 (2003) 45034-45039
    • (2003) J Biol Chem , vol.278 , pp. 45034-45039
    • Liu, J.1    Batkai, S.2    Pacher, P.3
  • 27
    • 1842480410 scopus 로고    scopus 로고
    • Host factors and failure of interferon-alpha treatment in hepatitis C virus
    • Gao B., Hong F., and Radaeva S. Host factors and failure of interferon-alpha treatment in hepatitis C virus. Hepatology 39 (2004) 880-890
    • (2004) Hepatology , vol.39 , pp. 880-890
    • Gao, B.1    Hong, F.2    Radaeva, S.3
  • 28
    • 33845737858 scopus 로고    scopus 로고
    • Impact of hepatic steatosis on viral kinetics and treatment outcome during antiviral treatment of chronic HCV infection
    • DITTO-HCV Study Group
    • Westin J., Lagging M., Dhillon A.P., et al., DITTO-HCV Study Group. Impact of hepatic steatosis on viral kinetics and treatment outcome during antiviral treatment of chronic HCV infection. J Viral Hepatol 14 (2007) 29-35
    • (2007) J Viral Hepatol , vol.14 , pp. 29-35
    • Westin, J.1    Lagging, M.2    Dhillon, A.P.3
  • 29
    • 33748584922 scopus 로고    scopus 로고
    • Cannabis use improves retention and virological outcomes in patients treated for hepatitis C
    • Sylvestre D.L., Clements B.J., and Malibu Y. Cannabis use improves retention and virological outcomes in patients treated for hepatitis C. Eur J Gastroenterol Hepatol 18 (2006) 1057-1063
    • (2006) Eur J Gastroenterol Hepatol , vol.18 , pp. 1057-1063
    • Sylvestre, D.L.1    Clements, B.J.2    Malibu, Y.3
  • 30
    • 34548499520 scopus 로고    scopus 로고
    • The endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species
    • Siegmund S.V., Qian T., de Minicis S., et al. The endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species. FASEB J 21 (2007) 2798-2806
    • (2007) FASEB J , vol.21 , pp. 2798-2806
    • Siegmund, S.V.1    Qian, T.2    de Minicis, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.