-
1
-
-
33748703859
-
The endocannabinoid system as an emerging target for pharmacotherapy
-
Pacher P., Bátkai S., and Kunos G. The endocannabinoid system as an emerging target for pharmacotherapy. Pharmacol Rev 58 (2006) 389-462
-
(2006)
Pharmacol Rev
, vol.58
, pp. 389-462
-
-
Pacher, P.1
Bátkai, S.2
Kunos, G.3
-
2
-
-
0034928628
-
Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis
-
Bátkai S., Járai Z., Wagner J.A., et al. Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. Nat Med 7 (2001) 827-832
-
(2001)
Nat Med
, vol.7
, pp. 827-832
-
-
Bátkai, S.1
Járai, Z.2
Wagner, J.A.3
-
3
-
-
34548444632
-
Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats
-
Bátkai S., Mukhopadhyay P., Harvey-White J., et al. Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. Am J Physiol Heart Circ Physiol 293 (2007) H1689-H1695
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Bátkai, S.1
Mukhopadhyay, P.2
Harvey-White, J.3
-
4
-
-
27144472559
-
Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats
-
Gaskari S.A., Liu H., Moezi L., et al. Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats. Br J Pharmacol 146 (2005) 315-323
-
(2005)
Br J Pharmacol
, vol.146
, pp. 315-323
-
-
Gaskari, S.A.1
Liu, H.2
Moezi, L.3
-
5
-
-
0036142225
-
Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat
-
Ros J., Clària J., To-Figueras J., et al. Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat. Gastroenterology 122 (2002) 85-93
-
(2002)
Gastroenterology
, vol.122
, pp. 85-93
-
-
Ros, J.1
Clària, J.2
To-Figueras, J.3
-
6
-
-
15744388722
-
Antifibrogenic role of the cannabinoid receptor CB2 in the liver
-
Julien B., Grenard P., Teixeira-Clerc F., et al. Antifibrogenic role of the cannabinoid receptor CB2 in the liver. Gastroenterology 128 (2005) 742-755
-
(2005)
Gastroenterology
, vol.128
, pp. 742-755
-
-
Julien, B.1
Grenard, P.2
Teixeira-Clerc, F.3
-
7
-
-
33745003240
-
CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis
-
Teixeira-Clerc F., Julien B., Grenard P., et al. CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis. Nat Med 12 (2006) 672-676
-
(2006)
Nat Med
, vol.12
, pp. 672-676
-
-
Teixeira-Clerc, F.1
Julien, B.2
Grenard, P.3
-
8
-
-
34547423962
-
Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats
-
Gary-Bobo M., Elachouri G., et al. Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats. Hepatology 46 (2007) 122-129
-
(2007)
Hepatology
, vol.46
, pp. 122-129
-
-
Gary-Bobo, M.1
Elachouri, G.2
-
9
-
-
20944436157
-
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
-
Osei-Hyiaman D., DePetrillo M., Pacher P., et al. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest 115 (2005) 1298-1305
-
(2005)
J Clin Invest
, vol.115
, pp. 1298-1305
-
-
Osei-Hyiaman, D.1
DePetrillo, M.2
Pacher, P.3
-
10
-
-
38649114788
-
Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver
-
(in press)
-
Jeong W.I., Osei-Hyiaman D., Park O., et al. Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell Metab 7 (2008) (in press)
-
(2008)
Cell Metab
, vol.7
-
-
Jeong, W.I.1
Osei-Hyiaman, D.2
Park, O.3
-
11
-
-
21344472982
-
Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C
-
Hézode C., Roudot-Thoraval F., Nguyen S., et al. Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C. Hepatology 42 (2005) 63-71
-
(2005)
Hepatology
, vol.42
, pp. 63-71
-
-
Hézode, C.1
Roudot-Thoraval, F.2
Nguyen, S.3
-
12
-
-
38649131428
-
Daily cannabis use: a novel risk factor of steatosis severity in patients with chronic hepatitis C
-
Hézode C., Zafrani E.S., Roudot-Thoraval F., et al. Daily cannabis use: a novel risk factor of steatosis severity in patients with chronic hepatitis C. Gastroenterology 134 (2008) 432-439
-
(2008)
Gastroenterology
, vol.134
, pp. 432-439
-
-
Hézode, C.1
Zafrani, E.S.2
Roudot-Thoraval, F.3
-
13
-
-
1842866963
-
CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
-
Ravinet Trillou C., Delgorge C., Menet C., et al. CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity. Int J Obes Relat Metab Disord 28 (2004) 640-648
-
(2004)
Int J Obes Relat Metab Disord
, vol.28
, pp. 640-648
-
-
Ravinet Trillou, C.1
Delgorge, C.2
Menet, C.3
-
14
-
-
27844463517
-
Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
-
Rimonabant in Obesity-Lipids Study Group
-
Després J.P., Golay A., Sjöström L., and Rimonabant in Obesity-Lipids Study Group. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N Engl J Med 353 (2005) 2121-2134
-
(2005)
N Engl J Med
, vol.353
, pp. 2121-2134
-
-
Després, J.P.1
Golay, A.2
Sjöström, L.3
-
15
-
-
32644441249
-
Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial
-
RIO-North America Study Group
-
Pi-Sunyer F.X., Aronne L.J., Heshmati H.M., et al., RIO-North America Study Group. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA 295 (2006) 761-775
-
(2006)
JAMA
, vol.295
, pp. 761-775
-
-
Pi-Sunyer, F.X.1
Aronne, L.J.2
Heshmati, H.M.3
-
16
-
-
17144382751
-
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
-
RIO-Europe Study Group
-
Van Gaal L.F., Rissanen A.M., Scheen A.J., et al., RIO-Europe Study Group. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 365 (2005) 1389-1397
-
(2005)
Lancet
, vol.365
, pp. 1389-1397
-
-
Van Gaal, L.F.1
Rissanen, A.M.2
Scheen, A.J.3
-
17
-
-
32044464960
-
Activation of cannabinoid CB1 receptors induces glucose intolerance in rats
-
Bermúdez-Siva F.J., Serrano A., Diaz-Molina F.J., et al. Activation of cannabinoid CB1 receptors induces glucose intolerance in rats. Eur J Pharmacol 531 (2006) 282-284
-
(2006)
Eur J Pharmacol
, vol.531
, pp. 282-284
-
-
Bermúdez-Siva, F.J.1
Serrano, A.2
Diaz-Molina, F.J.3
-
18
-
-
13244249625
-
Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice
-
Liu Y.L., Connoley I.P., Wilson C.A., et al. Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice. Int J Obes (Lond) 29 (2005) 183-187
-
(2005)
Int J Obes (Lond)
, vol.29
, pp. 183-187
-
-
Liu, Y.L.1
Connoley, I.P.2
Wilson, C.A.3
-
19
-
-
12744260206
-
The anti-obesity effect of rimonabant is associated with an improved serum lipid profile
-
Poirier B., Bidouard J.P., Cadrouvele C., et al. The anti-obesity effect of rimonabant is associated with an improved serum lipid profile. Diabetes Obes Metab 7 (2005) 65-72
-
(2005)
Diabetes Obes Metab
, vol.7
, pp. 65-72
-
-
Poirier, B.1
Bidouard, J.P.2
Cadrouvele, C.3
-
20
-
-
0037304290
-
Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice
-
Ravinet Trillou C., Arnone M., Delgorge C., et al. Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice. Am J Physiol Regul Integr Comp Physiol 284 (2003) R345-R353
-
(2003)
Am J Physiol Regul Integr Comp Physiol
, vol.284
-
-
Ravinet Trillou, C.1
Arnone, M.2
Delgorge, C.3
-
21
-
-
33751001942
-
Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study
-
RIO-Diabetes Study Group
-
Scheen A.J., Finer N., Hollander P., et al., RIO-Diabetes Study Group. Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study. Lancet 368 (2006) 1660-1672
-
(2006)
Lancet
, vol.368
, pp. 1660-1672
-
-
Scheen, A.J.1
Finer, N.2
Hollander, P.3
-
22
-
-
0023155534
-
Hepatic triacylglycerol accumulation induced by ethanol and carbon tetrachloride: interactions with essential fatty acids and prostaglandins
-
Cunnane S.C. Hepatic triacylglycerol accumulation induced by ethanol and carbon tetrachloride: interactions with essential fatty acids and prostaglandins. Alc Clin Exp Res 11 (1987) 25-30
-
(1987)
Alc Clin Exp Res
, vol.11
, pp. 25-30
-
-
Cunnane, S.C.1
-
23
-
-
16844378302
-
Hepatitis C virus-induced hepatocellular steatosis
-
Castera L., Chouteau P., Hézode C., et al. Hepatitis C virus-induced hepatocellular steatosis. Am J Gastroenterol 100 (2005) 711-715
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 711-715
-
-
Castera, L.1
Chouteau, P.2
Hézode, C.3
-
24
-
-
0028108372
-
Inactivation of Kupffer cells prevents early alcohol-induced liver injury
-
Adachi Y., Bradford B., Gao W., et al. Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 20 (1994) 453-460
-
(1994)
Hepatology
, vol.20
, pp. 453-460
-
-
Adachi, Y.1
Bradford, B.2
Gao, W.3
-
25
-
-
13744255589
-
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
-
Duffield J.S., Forbes S.J., Constandinou C.M., et al. Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Invest 115 (2005) 56-65
-
(2005)
J Clin Invest
, vol.115
, pp. 56-65
-
-
Duffield, J.S.1
Forbes, S.J.2
Constandinou, C.M.3
-
26
-
-
0242497230
-
Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor
-
Liu J., Batkai S., Pacher P., et al. Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor. J Biol Chem 278 (2003) 45034-45039
-
(2003)
J Biol Chem
, vol.278
, pp. 45034-45039
-
-
Liu, J.1
Batkai, S.2
Pacher, P.3
-
27
-
-
1842480410
-
Host factors and failure of interferon-alpha treatment in hepatitis C virus
-
Gao B., Hong F., and Radaeva S. Host factors and failure of interferon-alpha treatment in hepatitis C virus. Hepatology 39 (2004) 880-890
-
(2004)
Hepatology
, vol.39
, pp. 880-890
-
-
Gao, B.1
Hong, F.2
Radaeva, S.3
-
28
-
-
33845737858
-
Impact of hepatic steatosis on viral kinetics and treatment outcome during antiviral treatment of chronic HCV infection
-
DITTO-HCV Study Group
-
Westin J., Lagging M., Dhillon A.P., et al., DITTO-HCV Study Group. Impact of hepatic steatosis on viral kinetics and treatment outcome during antiviral treatment of chronic HCV infection. J Viral Hepatol 14 (2007) 29-35
-
(2007)
J Viral Hepatol
, vol.14
, pp. 29-35
-
-
Westin, J.1
Lagging, M.2
Dhillon, A.P.3
-
29
-
-
33748584922
-
Cannabis use improves retention and virological outcomes in patients treated for hepatitis C
-
Sylvestre D.L., Clements B.J., and Malibu Y. Cannabis use improves retention and virological outcomes in patients treated for hepatitis C. Eur J Gastroenterol Hepatol 18 (2006) 1057-1063
-
(2006)
Eur J Gastroenterol Hepatol
, vol.18
, pp. 1057-1063
-
-
Sylvestre, D.L.1
Clements, B.J.2
Malibu, Y.3
-
30
-
-
34548499520
-
The endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species
-
Siegmund S.V., Qian T., de Minicis S., et al. The endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species. FASEB J 21 (2007) 2798-2806
-
(2007)
FASEB J
, vol.21
, pp. 2798-2806
-
-
Siegmund, S.V.1
Qian, T.2
de Minicis, S.3
|