CB2 cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion

Journal of Molecular and Cellular Cardiology

Volumn 46, Issue 5, 2009, Pages 612-620

  Montecucco, Fabrizio ^a   Lenglet, Sébastien ^a   Braunersreuther, Vincent ^a   Burger, Fabienne ^a   Pelli, Graziano ^a   Bertolotto, Maria ^b   Mach, François ^a   Steffens, Sabine ^a  

^a Foundation for Medical Research   (Switzerland)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Cardioprotection; CB2 cannabinoid receptor; Kinase activation; Myocardial ischemia reperfusion; Oxidative stress

Indexed keywords

1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; CANNABINOID 2 RECEPTOR; CD11B ANTIGEN; CD18 ANTIGEN; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHOTRANSFERASE; TROPONIN I; TUMOR NECROSIS FACTOR ALPHA; UO 126;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; C57BL 6 MOUSE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REPERFUSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD11B; CANNABINOIDS; CELL MOVEMENT; CHEMOTACTIC FACTORS; DISEASE MODELS, ANIMAL; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTRACELLULAR SPACE; MICE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NEUTROPHILS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECEPTOR, CANNABINOID, CB2; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 63349100859     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2008.12.014     Document Type: Article

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