Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of inflammatory and neuropathic pain

European Journal of Neuroscience

Volumn 20, Issue 9, 2004, Pages 2311-2320

  Elmes, Steven J R ^a   Jhaveri, Maulik D ^a   Smart, Darren ^b   Kendall, David A ^a   Chapman, Victoria ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

CB2 receptor; Electrophysiology; Inflammation; Neuropathy; Nociception

Indexed keywords

CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR AGONIST; RIMONABANT; 1,1 DIMETHYLBUTYL 1 DEOXY DELTA(9) THC; 1,1-DIMETHYLBUTYL-1-DEOXY-DELTA(9)-THC; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; BORNANE DERIVATIVE; CANNABINOID; CANNABINOID 1 RECEPTOR; CARRAGEENAN; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; INFLAMMATION; MALE; NEUROMODULATION; NEUROPATHIC PAIN; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTIVE FIELD; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL; ACTION POTENTIAL; ANIMAL; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; INJURY; LIGATION; METABOLISM; NERVE CELL INHIBITION; NEURALGIA; NOCICEPTIVE RECEPTOR; PATHOPHYSIOLOGY; PERIPHERAL NEUROPATHY; PHYSIOLOGY; POSTERIOR HORN CELL; REACTION TIME; SENSORY RECEPTOR; SPINAL NERVE; SPRAGUE DAWLEY RAT; STIMULATION;

ACTION POTENTIALS; ANIMALS; BORNANES; CANNABINOIDS; CARRAGEENAN; DISEASE MODELS, ANIMAL; INFLAMMATION; LIGATION; MALE; NEURAL INHIBITION; NEURALGIA; NOCICEPTORS; PERIPHERAL NERVOUS SYSTEM DISEASES; PHYSICAL STIMULATION; PIPERIDINES; POSTERIOR HORN CELLS; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2; RECEPTORS, SENSORY; SPINAL NERVES;

EID: 8144229133     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2004.03690.x     Document Type: Article

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