The endocannabinoid system in human keratinocytes: Evidence that anandamide inhibits epidermal differentiation through CB1 receptor-dependent inhibition of protein kinase C, activating protein-1, and transglutaminase

Journal of Biological Chemistry

Volumn 278, Issue 36, 2003, Pages 33896-33903

  Maccarrone, Mauro ^a,b   Di Rienzo, Marianna ^c   Battista, Natalia ^c   Gasperi, Valeria ^c   Guerrieri, Pietro ^c   Rossi, Antonello ^c   Finazzi Agrò, Alessandro ^c  

^a UNIVERSITY OF TERAMO   (Italy)

^b Mondino Tor Vergata Santa Lucia Ctr   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; ENZYME INHIBITION; ENZYMES; GENES; METABOLISM; TISSUE;

PATHOPHYSIOLOGY;

BIOCHEMISTRY;

ANANDAMIDE; CANNABINOID; CANNABINOID 1 RECEPTOR; CHLORAMPHENICOL ACETYLTRANSFERASE; ENDOCANNABINOID; LIGAND; LORICRIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE D; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN KINASE C; UNCLASSIFIED DRUG; AMIDE; ARACHIDONIC ACID DERIVATIVE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CANNABINOID RECEPTOR; DRUG RECEPTOR; TRANSCRIPTION FACTOR AP 1; UNSATURATED FATTY ACID;

ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL IMMORTALIZATION; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; EPIDERMIS CELL; HUMAN; HUMAN CELL; KERATINOCYTE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; RECEPTOR GENE; CELL CULTURE; CELL DIVISION; CELL LINE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; EPIDERMIS; GENETIC TRANSFECTION; KINETICS; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; SIGNAL TRANSDUCTION; TIME;

ARACHIDONIC ACIDS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCANNABINOIDS; EPIDERMIS; FATTY ACIDS, UNSATURATED; HUMANS; KERATINOCYTES; KINETICS; POLYUNSATURATED ALKAMIDES; PROTEIN BINDING; PROTEIN KINASE C; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; TRANSFECTION; TRANSGLUTAMINASES; TUMOR CELLS, CULTURED;

EID: 0141668883     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303994200     Document Type: Article

References (55)

1. Maccarrone, M., and Finazzi-Agrò, A. (2002) Vitam. Horm. 65, 225-255
2. Sugiura, T., Kobayashi, Y., Oka, S., and Waku, K. (2002) Prostaglandins Leukot. Essent. Fatty Acids 66, 173-192
3. Mechoulam, R., Panikashvili, D., and Shohami, E. (2002) Trends Mol. Med. 8, 58-61
4. De Petrocellis, L., Bisogno, T., Maccarrone, M., Davis, J. B., Finazzi-Agrò, A., and Di Marzo, V. (2001) J. Biol. Chem. 276, 12856-12863
5. Jordt, S. E., and Julius, D. (2002) Cell 108, 421-430
6. Hillard, C. J., and Jarrahian, A. (2000) Chem. Phys. Lipids 108, 123-134
7. Ueda, N., Puffenbarger, R. A., Yamamoto, S., and Deutsch, D. G. (2000) Chem. Phys. Lipids 108, 107-121
8. Hansen, H. S., Moesgaard, B., Hansen, H. H., and Petersen, G. (2000) Chem. Phys. Lipids 108, 135-150
9. Dinh, T. P., Carpenter, D., Leslie, F. M., Freund, T. F., Katona, I., Sensi, S. L., Kathuria, S., and Piomelli, D. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 10819-10824
10. Fride, E. (2002) Prostaglandins Leukot. Essent. Fatty Acids 66, 221-233
11. Guzman, M., Sanchez, C., and Galve-Roperh, I. (2002) Pharmacol. Ther. 95, 175-184
12. Calignano, A., La Rana, G., Giuffrida, A., and Piomelli, D. (1998) Nature 394, 277-281
13. Calignano, A., La Rana, G., Loubet-Lescoulie, P., and Piomelli, D. (2000) Prog. Brain Res. 129, 471-482
14. Walker, J. M., and Huang, S. M. (2002) Prostaglandins Leukot. Essent. Fatty Acids 66, 235-242
15. Nakamura, A., and Shiomi, H. (1999) Jpn. J. Pharmacol. 79, 427-431
16. Berdyshev, E. V., Schmid, P. C., Dong, Z., and Schmid, H. H. (2000) Biochem. J. 346, 369-374
17. Bifulco, M., Laezza, C., Portella, G., Vitale, M., Orlando, P., De Petrocellis, L., and Di Marzo, V. (2001) FASEB J. 15, 2745-2747
18. Casanova, M. L., Blazquez, C., Martinez-Palacio, J., Villanueva, C., Fernandez-Acenero, M. J., Huffman, J. W., Torcano, J. L., and Guzman, M. (2003) J. Clin. Invest. 111, 43-50
19. Ellington, H. C., Cotter, M. A., Cameron, N. E., and Ross, R. A. (2002) Neuropharmacology 42, 966-975
20. Giang, D. K., and Cravatt, B. F. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 2238-2242
21. Boukamp, P., Petrussevska, R. T., Breitkreutz, D., Hornung, J., Markham, A., and Fusenig, N. E. (1998) J. Cell Biol. 106, 761-771
22. Savini, I., Catani, M. V., Rossi, A., Duranti, G., Melino, G., and Avigliano, L. (2002) J. Invest. Dermatol. 118, 372-379
23. Candi, E., Oddi, S., Terrinoni, A., Paradisi, A., Ranalli, M., Finazzi-Agrò, A., and Melino, G. (2001) J. Biol. Chem. 276, 35014-35023
24. Maccarrone, M., Lorenzon, T., Bari, M., Melino, G., and Finazzi-Agrò, A. (2000) J. Biol. Chem. 275, 31938-31945
25. Ross, R. A., Gibson, T. M., Brockie, H. C., Lesile, M., Pashmi, G., Craib, S. J., Di Marzo, V., and Pertwee, R. G. (2001) Br. J. Pharmacol. 132, 631-640
26. Maccarrone, M., Valensise, H., Bari, M., Lazzarin, N., Romanici, C., and Finazzi-Agrò, A. (2001) J. Immunol. 166, 7183-7189
27. Maccarrone, M., Bari, M., Lorenzon, T., Bisogno, T., Di Marzo, V., and Finazzi-Agrò, A. (2000) J. Biol. Chem. 275, 13484-13492
28. Hillard, C. J., Edgemond, W. S., Jarrahian, A., and Campbell, W. B. (1997) J. Neurochem. 69, 631-638
29. Maccarrone, M., Attinà, M., Cartoni, A., Bari, M., and Finazzi-Agrò, A. (2001) J. Neurochem. 76, 594-601
30. Moesgaard, B., Petersen, G., Jaroszewski, J. W., and Hansen, H. S. (2000) J. Lipid Res. 41, 985-990
31. Gubellini, P., Picconi, B., Bari, M., Battista, N., Calabresi, P., Centone, D., Bernardi, G., Finazzi-Agrò, A., and Maccarrone, M. (2002) J. Neurosci. 22, 6900-6907
32. Rossi, A., Catani, M. V., Candi, E., Bernassola, F., Puddu, P., and Melino, G. (2000) J. Invest. Dermatol. 115, 731-739
33. Steven, A. C., and Steinert, P. M. (1994) J. Cell Sci. 107, 693-700
34. Rossi, A., Jang, S. I., Ceci, R., Steinert, P. M., and Markova, N. G. (1998) J. Invest. Dermatol. 110, 34-40
35. Pertwee, R. G. (1997) Pharmacol. Ther. 74, 129-180
36. Lin, S., Khanolkar, A. D., Fan, P., Goutopoulos, A., Qin, C., Papahadjis, D., and Makriyannis, A. (1998) J. Med. Chem. 41, 5353-5361
37. Kunos, G., Járai, Z., Batkai, S., Goparaju, S. K., Ishac, E. J., Liu, J., Wang, L., and Wagner, J. A. (2000) Chem. Phys. Lipids 108, 159-168
38. Piomelli, D., Beltramo, M., Glasnapp, S., Lin, S. Y., Goutopoulos, A., Xie, X. Q., and Makriyannis, A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 5802-5807
39. Welter, J. F., and Eckert, R. L. (1995) Oncogene 11, 2681-2687
40. Deutsch, D. G., Glaser, S. T., Howell, J. M., Kunz, J. S., Puffenbarger, R. A., Hillard, C. J., and Abumrad, N. (2001) J. Biol. Chem. 276, 6967-6973
41. Day, T. A., Rakhshan, F., Deutsch, D. G., and Barker, E. L. (2001) Mol. Pharmacol. 59, 1369-1375
42. Bracey, M. H., Hanson, M. A., Masuda, K. R., Stevens, R. C., and Cravatt, B. F. (2002) Science 298, 1793-1796
43. Maccarrone, M., Bari, M., Battista, N., and Finazzi-Agrò, A. (2002) Blood 100, 4040-4048
44. Glaser, S. T., Abumrad, N. A., Fatade, F., Kaczocha, M., Studholme, K. M., and Deutsch, D. G. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 4269-4274
45. Cravatt, B. F., Demarest, K., Patricelli, M. P., Bracey, M. H., Giang, D. K., Martin, B. R., and Lichtman, A. H. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 9371-9376
46. Nemes, Z., and Steinert, P. M. (1999) Exp. Mol. Med. 31, 5-19
47. Kalinin, A. E., Kajava, A. V., and Steinert, P. M. (2002) Bioessays 24, 789-800
48. Eckert, R. L., Crish, J. F., and Robinson, N. A. (1997) Physiol. Rev. 77, 397-424
49. Rutberg, S. E., Saez, E., Glick, A., Dlugosz, A. A., Spiegelman, B. M., and Yuspa, S. H. (1996) Oncogene 13, 167-176
50. Rueda, D., Navarro, B., Martinez-Serrano, A., Guzman, M., and Galve-Roperh, I. (2002) J. Biol. Chem. 277, 46645-46650
51. Howlett, A. C., and Mukhopadhyay, S. (2000) Chem. Phys. Lipids 108, 53-70
52. McAllister, S. D., and Glass, M. (2002) Prostaglandins Leukot. Essent. Fatty Acids 66, 161-171
53. Olah, Z., Karai, L., and Iadarola, M. J. (2002) J. Biol. Chem. 277, 35752-35759
54. Garcia, D. E., Brown, S., Hille, B., and Mackie, K. (1998) J. Neurosci. 18, 2834-2841
55. Yamaji, K., Pada Sarker, K., Kawahara, K., Iino, S., Yamakuchi, M., Abeyama, K., Hashiguchi, T., and Maruyama, I. (2003) Thromb. Haemost. 89, 875-884