메뉴 건너뛰기




Volumn 74, Issue 4, 2003, Pages 486-496

The cannabinoid system and immune modulation

Author keywords

CB1; Chemotaxis; G protein; Marijuana; Th1 cells; Tumor

Indexed keywords

1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 2 METHYL 3 (1 NAPHTHOYL) 1 PROPYLINDOLE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; ANANDAMIDE; CANNABINOID; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID DERIVATIVE; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR AGONIST; CANNABIS; DEXANABINOL; G PROTEIN COUPLED RECEPTOR; RIMONABANT; TETRAHYDROCANNABINOL; UNCLASSIFIED DRUG;

EID: 0346350327     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0303101     Document Type: Review
Times cited : (442)

References (121)
  • 1
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens, L. M., Werb, Z. (2002) Inflammation and cancer. Nature 420, 860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 3
    • 0036467451 scopus 로고    scopus 로고
    • Direct and indirect inhibition of Th1 development by progesterone and glucocorticoids
    • Miyaura, H., Iwata, M. (2002) Direct and indirect inhibition of Th1 development by progesterone and glucocorticoids. J. Immunol. 168, 1087-1094.
    • (2002) J. Immunol. , vol.168 , pp. 1087-1094
    • Miyaura, H.1    Iwata, M.2
  • 4
    • 0036570698 scopus 로고    scopus 로고
    • Trends in histamine research: New functions during immune responses and hematopoiesis
    • Schneider, E., Rolli-Derkinderen, M., Arock, M., Dy, M. (2002) Trends in histamine research: new functions during immune responses and hematopoiesis. Trends Immunol. 23, 255-263.
    • (2002) Trends Immunol. , vol.23 , pp. 255-263
    • Schneider, E.1    Rolli-Derkinderen, M.2    Arock, M.3    Dy, M.4
  • 5
    • 0035210457 scopus 로고    scopus 로고
    • Norepinephrine and beta 2-adrenergic receptor stimulation regulate CD4+ T and B lymphocyte function in vitro and in vivo
    • Kohm, A. P., Sanders, V. M. (2001) Norepinephrine and beta 2-adrenergic receptor stimulation regulate CD4+ T and B lymphocyte function in vitro and in vivo. Pharmacol. Rev. 53, 487-525.
    • (2001) Pharmacol. Rev. , vol.53 , pp. 487-525
    • Kohm, A.P.1    Sanders, V.M.2
  • 6
    • 0032520733 scopus 로고    scopus 로고
    • Opioid modulation of immune responses: Effects on phagocyte and lymphoid cell populations
    • Eisenstein, T. K., Hilburger, M. E. (1998) Opioid modulation of immune responses: effects on phagocyte and lymphoid cell populations. J. Neuroimmunol. 83, 36-44.
    • (1998) J. Neuroimmunol. , vol.83 , pp. 36-44
    • Eisenstein, T.K.1    Hilburger, M.E.2
  • 9
    • 0029830331 scopus 로고    scopus 로고
    • Cannabis: Pharmacology and toxicology in animals and humans
    • Adams, I. B., Martin, B. R. (1996) Cannabis: pharmacology and toxicology in animals and humans. Addiction 91, 1585-1614.
    • (1996) Addiction , vol.91 , pp. 1585-1614
    • Adams, I.B.1    Martin, B.R.2
  • 11
    • 0036669791 scopus 로고    scopus 로고
    • Cannabinoids and multiple sclerosis
    • Pertwee, R. G. (2002) Cannabinoids and multiple sclerosis. Pharmacol. Ther. 95, 165-174.
    • (2002) Pharmacol. Ther. , vol.95 , pp. 165-174
    • Pertwee, R.G.1
  • 12
    • 0022472739 scopus 로고
    • Health aspects of cannabis
    • Hollister, L. E. (1986) Health aspects of cannabis. Pharmacol. Rev. 38, 1-20.
    • (1986) Pharmacol. Rev. , vol.38 , pp. 1-20
    • Hollister, L.E.1
  • 13
    • 0344505201 scopus 로고    scopus 로고
    • Drugs and immunity: Cannabinoids and their role in decreased resistance to infectious diseases
    • Cabral, G., Dove Pettit, D. (1998) Drugs and immunity: cannabinoids and their role in decreased resistance to infectious diseases. J. Neuroimmunol. 83, 116-123.
    • (1998) J. Neuroimmunol. , vol.83 , pp. 116-123
    • Cabral, G.1    Dove Pettit, D.2
  • 15
    • 0031811925 scopus 로고    scopus 로고
    • Cannabinoid receptors and immunity
    • Klein, T., Newton, C., Friedman, H. (1998) Cannabinoid receptors and immunity. Immunol. Today 19, 373-381.
    • (1998) Immunol. Today , vol.19 , pp. 373-381
    • Klein, T.1    Newton, C.2    Friedman, H.3
  • 17
    • 0033661798 scopus 로고    scopus 로고
    • Cannabinoid receptors and the regulation of immune response
    • Berdyshev, E. V. (2000) Cannabinoid receptors and the regulation of immune response. Chem. Phys. Lipids 108, 169-190.
    • (2000) Chem. Phys. Lipids , vol.108 , pp. 169-190
    • Berdyshev, E.V.1
  • 18
    • 0037207092 scopus 로고    scopus 로고
    • Effects of delta-9-tetrahydrocannabinol on human immune function and host defense
    • Roth, M. D., Baldwin, G. C., Tashkin, D. P. (2002) Effects of delta-9-tetrahydrocannabinol on human immune function and host defense. Chem. Phys. Lipids 121, 229-239.
    • (2002) Chem. Phys. Lipids , vol.121 , pp. 229-239
    • Roth, M.D.1    Baldwin, G.C.2    Tashkin, D.P.3
  • 19
    • 33947489961 scopus 로고
    • Isolation, structure, and partial synthesis of an active constituent of hashish
    • Gaoni, Y., Mechoulam, R. (1964) Isolation, structure, and partial synthesis of an active constituent of hashish. J. Am. Chem. Soc. 86, 1646-1647.
    • (1964) J. Am. Chem. Soc. , vol.86 , pp. 1646-1647
    • Gaoni, Y.1    Mechoulam, R.2
  • 20
    • 0023914862 scopus 로고
    • Nonclassical cannabinoid analgetics inhibit adenylate cyclase: Development of a cannabinoid receptor model
    • Howlett, A. C., Johnson, M. R., Melvin, L. S., Milne, G. M. (1988) Nonclassical cannabinoid analgetics inhibit adenylate cyclase: development of a cannabinoid receptor model. Mol. Pharmacol. 33, 297-302.
    • (1988) Mol. Pharmacol. , vol.33 , pp. 297-302
    • Howlett, A.C.1    Johnson, M.R.2    Melvin, L.S.3    Milne, G.M.4
  • 24
    • 0030425575 scopus 로고    scopus 로고
    • Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands
    • Showalter, V. M., Compton, D. R., Martin, B. R., Abood, M. E. (1996) Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. J. Pharmacol. Exp. Ther. 278, 989-999.
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 989-999
    • Showalter, V.M.1    Compton, D.R.2    Martin, B.R.3    Abood, M.E.4
  • 32
    • 0032884257 scopus 로고    scopus 로고
    • Biosynthesis and turnover of anandamide and other N-acylethanolamines in peritoneal macrophages
    • Kuwae, T., Shiota, Y., Schmid, P. C., Krebsbach, R., Schmid, H. H. (1999) Biosynthesis and turnover of anandamide and other N-acylethanolamines in peritoneal macrophages. FEBS Lett. 459, 123-127.
    • (1999) FEBS Lett. , vol.459 , pp. 123-127
    • Kuwae, T.1    Shiota, Y.2    Schmid, P.C.3    Krebsbach, R.4    Schmid, H.H.5
  • 36
    • 0036019386 scopus 로고    scopus 로고
    • Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance
    • Sugiura, T., Kobayashi, Y., Oka, S., Waku, K. (2002) Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. Prostaglandins Leukot. Essent. Fatty Acids 66, 173-192.
    • (2002) Prostaglandins Leukot. Essent. Fatty Acids , vol.66 , pp. 173-192
    • Sugiura, T.1    Kobayashi, Y.2    Oka, S.3    Waku, K.4
  • 37
    • 0029904838 scopus 로고    scopus 로고
    • Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
    • Cravatt, B. E., Giang, D. K., Mayfield, S. P., Boger, D. L., Lerner, R. A., Gilula, N. B. (1996) Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature 384, 83-87.
    • (1996) Nature , vol.384 , pp. 83-87
    • Cravatt, B.E.1    Giang, D.K.2    Mayfield, S.P.3    Boger, D.L.4    Lerner, R.A.5    Gilula, N.B.6
  • 40
    • 0025325535 scopus 로고
    • Structure of cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda, L. A., Lolait, S. J., Brownstein, M. J., Young, A. C., Bonner, T. I. (1990) Structure of cannabinoid receptor and functional expression of the cloned cDNA. Nature 346, 561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 41
    • 0025878961 scopus 로고
    • Molecular cloning of a human canuabinoid receptor which is also expressed in testis
    • Gerard, C. M., Molhlereau, C., Vassart, G., Parmentier, M. (1991) Molecular cloning of a human canuabinoid receptor which is also expressed in testis. Biochem. J. 279, 129-134.
    • (1991) Biochem. J. , vol.279 , pp. 129-134
    • Gerard, C.M.1    Molhlereau, C.2    Vassart, G.3    Parmentier, M.4
  • 42
    • 0028813410 scopus 로고
    • Cloning and sequencing of a cDNA encoding the mouse brain-type cannabinoid receptor protein
    • Chakrabarti, A., Onaivi, E., Chaudhuri, G. (1995) Cloning and sequencing of a cDNA encoding the mouse brain-type cannabinoid receptor protein. DNA Seq. 5, 385-388.
    • (1995) DNA Seq. , vol.5 , pp. 385-388
    • Chakrabarti, A.1    Onaivi, E.2    Chaudhuri, G.3
  • 43
    • 0035829972 scopus 로고    scopus 로고
    • Schizophrenia and the cannabinoid receptor type 1 (CB1): Association study using a single-base polymorphism in coding exon 1
    • Leroy, S., Griffon, N., Bourdel, M. C., Olie, J. P., Poirier, M. F., Krebs, M. O. (2001) Schizophrenia and the cannabinoid receptor type 1 (CB1): association study using a single-base polymorphism in coding exon 1. Am. J. Med. Genet. 105, 749-752.
    • (2001) Am. J. Med. Genet. , vol.105 , pp. 749-752
    • Leroy, S.1    Griffon, N.2    Bourdel, M.C.3    Olie, J.P.4    Poirier, M.F.5    Krebs, M.O.6
  • 44
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro, S., Thomas, K. L., Abu-Shaar, M. (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature 365, 61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 46
    • 0037135209 scopus 로고    scopus 로고
    • Cloning and molecular characterization of the rat CB2 cannabinoid receptor
    • Brown, S. M., Wager-Miller, J., Mackie, K. (2002) Cloning and molecular characterization of the rat CB2 cannabinoid receptor. Biochim. Biophys. Acta 1576, 255-264.
    • (2002) Biochim. Biophys. Acta , vol.1576 , pp. 255-264
    • Brown, S.M.1    Wager-Miller, J.2    Mackie, K.3
  • 47
    • 0032504237 scopus 로고    scopus 로고
    • G protein-coupled receptors. I. Diversity of receptor-ligand interactions
    • Ji, T. H., Grossmann, M., Ji, I. (1998) G protein-coupled receptors. I. Diversity of receptor-ligand interactions. J. Biol. Chem. 273, 17299-17302.
    • (1998) J. Biol. Chem. , vol.273 , pp. 17299-17302
    • Ji, T.H.1    Grossmann, M.2    Ji, I.3
  • 48
    • 0032563291 scopus 로고    scopus 로고
    • G protein-coupled receptors
    • Lefkowitz, R. J. (1998) G protein-coupled receptors. J. Biol. Chem. 273, 18677-18680.
    • (1998) J. Biol. Chem. , vol.273 , pp. 18677-18680
    • Lefkowitz, R.J.1
  • 49
    • 0035089760 scopus 로고    scopus 로고
    • Regulation of interleukin-12 production by G-protein-coupled receptors
    • Braun, M. C., Kelsall, B. L. (2001) Regulation of interleukin-12 production by G-protein-coupled receptors. Microbes Infect. 3, 99-107.
    • (2001) Microbes Infect. , vol.3 , pp. 99-107
    • Braun, M.C.1    Kelsall, B.L.2
  • 50
    • 0031660109 scopus 로고    scopus 로고
    • Cannabinoid receptor activation differentially regulates the various adenylyl cyclase isozymes
    • Rhee, M. H., Bayewitch, M., Avidor-Reiss, T., Levy, R., Vogel, Z. (1998) Cannabinoid receptor activation differentially regulates the various adenylyl cyclase isozymes. J. Neurochem. 71, 1525-1534.
    • (1998) J. Neurochem. , vol.71 , pp. 1525-1534
    • Rhee, M.H.1    Bayewitch, M.2    Avidor-Reiss, T.3    Levy, R.4    Vogel, Z.5
  • 52
    • 0037014598 scopus 로고    scopus 로고
    • Role of intracellular loops of cannabinoid CB(1) receptor in functional interaction with G(alpha16)
    • Ho, B. Y., Current, L., Drewett, J. G. (2002) Role of intracellular loops of cannabinoid CB(1) receptor in functional interaction with G(alpha16). FEBS Lett. 522, 130-134.
    • (2002) FEBS Lett. , vol.522 , pp. 130-134
    • Ho, B.Y.1    Current, L.2    Drewett, J.G.3
  • 53
    • 0028823316 scopus 로고
    • Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor
    • Mackie, K., Lai, Y., Westenbrock, R., Mitchell, R. (1995) Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor. J. Neurosci. 15, 6552-6561.
    • (1995) J. Neurosci. , vol.15 , pp. 6552-6561
    • Mackie, K.1    Lai, Y.2    Westenbrock, R.3    Mitchell, R.4
  • 54
    • 0032523019 scopus 로고    scopus 로고
    • Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor
    • Garcia, D. E., Brown, S., Hille, B., Mackie, K. (1998) Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor. J. Neurosci. 18, 2834-2841.
    • (1998) J. Neurosci. , vol.18 , pp. 2834-2841
    • Garcia, D.E.1    Brown, S.2    Hille, B.3    Mackie, K.4
  • 55
    • 0032550202 scopus 로고    scopus 로고
    • Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: Neurovascular regulation
    • Prevot, V., Rialas, C. M., Croix, D., Salzet, M., Dupouy, J. P., Poulain, P., Beauvillain, J. C., Stefano, G. B. (1998) Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: neurovascular regulation. Brain Res. 790, 236-244.
    • (1998) Brain Res. , vol.790 , pp. 236-244
    • Prevot, V.1    Rialas, C.M.2    Croix, D.3    Salzet, M.4    Dupouy, J.P.5    Poulain, P.6    Beauvillain, J.C.7    Stefano, G.B.8
  • 56
    • 0029989044 scopus 로고    scopus 로고
    • Signaling pathway associated with stimulation of CB2 peripheral cannabinoid receptor. Involvement of both mitogen-activated protein kinase and induction of Krox-24 expression
    • Bouaboula, M., Poinot-Chazel, C., Marchand, J., Canat, X., Bourrie, B., Rinaldi-Carmona, M., Calandra, B., Le Fur, G., Casellas, P. (1996) Signaling pathway associated with stimulation of CB2 peripheral cannabinoid receptor. Involvement of both mitogen-activated protein kinase and induction of Krox-24 expression. Eur. J. Biochem. 237, 704-711.
    • (1996) Eur. J. Biochem. , vol.237 , pp. 704-711
    • Bouaboula, M.1    Poinot-Chazel, C.2    Marchand, J.3    Canat, X.4    Bourrie, B.5    Rinaldi-Carmona, M.6    Calandra, B.7    Le Fur, G.8    Casellas, P.9
  • 57
    • 0029790065 scopus 로고    scopus 로고
    • 9-tetrahydrocannabinol is mediated through the inhibition of nuclear factor-κB/Rel activation
    • 9-tetrahydrocannabinol is mediated through the inhibition of nuclear factor-κB/Rel activation. Mol. Pharmacol. 50, 334-341.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 334-341
    • Jeon, Y.J.1    Yang, K.2    Pulaski, J.T.3    Kaminski, N.E.4
  • 58
    • 0030890230 scopus 로고    scopus 로고
    • 9-tetrahydrocannabinol is mediated by nuclear factor κB and CB1 cannabinoid receptor
    • 9-tetrahydrocannabinol is mediated by nuclear factor κB and CB1 cannabinoid receptor. DNA Cell Biol. 16, 301-309.
    • (1997) DNA Cell Biol. , vol.16 , pp. 301-309
    • Daaka, Y.1    Zhu, W.2    Friedman, H.3    Klein, T.W.4
  • 59
    • 0035967179 scopus 로고    scopus 로고
    • Neurobiology cannabinoids act backwards
    • Christie, M. J., Vaughan, C. W. (2001) Neurobiology cannabinoids act backwards. Nature 410, 527-530.
    • (2001) Nature , vol.410 , pp. 527-530
    • Christie, M.J.1    Vaughan, C.W.2
  • 60
    • 0035971102 scopus 로고    scopus 로고
    • Neurobiology. How cannabinoids work in the brain
    • Barinaga, M. (2001) Neurobiology. How cannabinoids work in the brain. Science 291, 2530-2531.
    • (2001) Science , vol.291 , pp. 2530-2531
    • Barinaga, M.1
  • 61
    • 0035499974 scopus 로고    scopus 로고
    • Modulation of transmitter release via presynaptic cannabinoid receptors
    • Schlicker, E., Kathmann, M. (2001) Modulation of transmitter release via presynaptic cannabinoid receptors. Trends Pharmacol. Sci. 22, 565-572.
    • (2001) Trends Pharmacol. Sci. , vol.22 , pp. 565-572
    • Schlicker, E.1    Kathmann, M.2
  • 62
    • 0035053627 scopus 로고    scopus 로고
    • Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells
    • Kreitzer, A. C., Regehr, W. G. (2001) Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells. Neuron 29, 717-727.
    • (2001) Neuron , vol.29 , pp. 717-727
    • Kreitzer, A.C.1    Regehr, W.G.2
  • 63
    • 0035050883 scopus 로고    scopus 로고
    • Endogenous cannabinoids mediate retrograde signals front depolarized postsynaptic neurons to presynaptic terminals
    • Ohno-Shosaku, T., Maejima, T., Kano, M. (2001) Endogenous cannabinoids mediate retrograde signals front depolarized postsynaptic neurons to presynaptic terminals. Neuron 29, 729-738.
    • (2001) Neuron , vol.29 , pp. 729-738
    • Ohno-Shosaku, T.1    Maejima, T.2    Kano, M.3
  • 64
    • 0035967145 scopus 로고    scopus 로고
    • Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses
    • Wilson. R. I., Nicoll, R. A. (2001) Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses. Nature 410, 588-592.
    • (2001) Nature , vol.410 , pp. 588-592
    • Wilson, R.I.1    Nicoll, R.A.2
  • 66
    • 0037442799 scopus 로고    scopus 로고
    • Impairment of antimicrobial activity and nitric oxide Production in alveolar macrophages from smokers of marijuana and cocaine
    • Shay, A. H., Choi, R., Whittaker K., Salehi, K., Kitchen, C. M., Tashkin, D. P., Roth, M. D., Baldwin, G. C. (2003) Impairment of antimicrobial activity and nitric oxide Production in alveolar macrophages from smokers of marijuana and cocaine. J. Infect. Dis. 187, 700-704.
    • (2003) J. Infect. Dis. , vol.187 , pp. 700-704
    • Shay, A.H.1    Choi, R.2    Whittaker, K.3    Salehi, K.4    Kitchen, C.M.5    Tashkin, D.P.6    Roth, M.D.7    Baldwin, G.C.8
  • 67
    • 0023901830 scopus 로고
    • The Sydney AIDS project: Development of acquired immunodeficieney syndrome in a group of HIV seropositive homosexual men
    • Tindall, B., Cooper, D. A., Donovan, B., Barnes, T., Philpot, C. R., Gold, J., Penny, R. (1988) The Sydney AIDS project: development of acquired immunodeficieney syndrome in a group of HIV seropositive homosexual men. Aust. N. Z. J. Med. 18, 8-15.
    • (1988) Aust. N. Z. J. Med. , vol.18 , pp. 8-15
    • Tindall, B.1    Cooper, D.A.2    Donovan, B.3    Barnes, T.4    Philpot, C.R.5    Gold, J.6    Penny, R.7
  • 69
    • 0022531578 scopus 로고
    • Marijuana smoking-possible cause of head and neck carcinoma in young patients
    • Donald, P. J. (1986) Marijuana smoking-possible cause of head and neck carcinoma in young patients. Otolaryngol. Head Neck Surg. 94, 517-521.
    • (1986) Otolaryngol. Head Neck Surg. , vol.94 , pp. 517-521
    • Donald, P.J.1
  • 71
    • 0036270406 scopus 로고    scopus 로고
    • Altered cannabinoid receptor mRNA expression in peripheral blood mononuclear cells from marijuana smokers
    • Nong, L., Newton, C., Cheng, Q., Friedman, H., Roth, M. D., Klein, T. W. (2002) Altered cannabinoid receptor mRNA expression in peripheral blood mononuclear cells from marijuana smokers. J. Neuroimmunol. 127, 169-176.
    • (2002) J. Neuroimmunol. , vol.127 , pp. 169-176
    • Nong, L.1    Newton, C.2    Cheng, Q.3    Friedman, H.4    Roth, M.D.5    Klein, T.W.6
  • 72
    • 0016827849 scopus 로고
    • The effect of chronic marijuana usage on the immunological status of rhesus monkeys
    • Daul, C. B., Heath, R. G. (1975) The effect of chronic marijuana usage on the immunological status of rhesus monkeys. Life Sci. 17, 875-882.
    • (1975) Life Sci. , vol.17 , pp. 875-882
    • Daul, C.B.1    Heath, R.G.2
  • 74
    • 0027103851 scopus 로고
    • Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation
    • Kaminski, N. E., Abood, M. E., Kessler, F. K., Martin, B. R., Schatz, A. R. (1992) Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation. Mol. Pharmacol. 42, 736-742.
    • (1992) Mol. Pharmacol. , vol.42 , pp. 736-742
    • Kaminski, N.E.1    Abood, M.E.2    Kessler, F.K.3    Martin, B.R.4    Schatz, A.R.5
  • 76
    • 0029066994 scopus 로고
    • Expression of cannabinoid receptor mRNA in murine and human leukocytes
    • (B. Sharp, T. K. Eisenstein, J. J. Madden, H. Friedman, eds.), New York, NY, Plenum
    • Daaka, Y., Klein, T. W., Friedman, H. (1995) Expression of cannabinoid receptor mRNA in murine and human leukocytes. In Advances in Experimental Medicine and Biology, vol. 373 (B. Sharp, T. K. Eisenstein, J. J. Madden, H. Friedman, eds.), New York, NY, Plenum, 91-96.
    • (1995) Advances in Experimental Medicine and Biology , vol.373 , pp. 91-96
    • Daaka, Y.1    Klein, T.W.2    Friedman, H.3
  • 77
    • 0031062297 scopus 로고    scopus 로고
    • Cannabinoid receptors CB1 and CB2: A characterization of expression and adenvlate cyclase modulation within the immune system
    • Schatz, A. R., Lee, M., Condie, R. B., Pulaski, J. T., Kaminski, N. E. (1997) Cannabinoid receptors CB1 and CB2: a characterization of expression and adenvlate cyclase modulation within the immune system. Toxicol. Appl. Pharmacol. 142, 278-287.
    • (1997) Toxicol. Appl. Pharmacol. , vol.142 , pp. 278-287
    • Schatz, A.R.1    Lee, M.2    Condie, R.B.3    Pulaski, J.T.4    Kaminski, N.E.5
  • 78
    • 0034597039 scopus 로고    scopus 로고
    • Anti-CD40, anti-CD3, and IL-2 stimulation induce contrasting changes in CB1 mRNA expression in mouse splenocytes
    • Noe, S. N., Newton, C., Widen, R., Friedman, H., Klein, T. W. (2000) Anti-CD40, anti-CD3, and IL-2 stimulation induce contrasting changes in CB1 mRNA expression in mouse splenocytes. J. Neuroimmunol. 110, 161-167.
    • (2000) J. Neuroimmunol. , vol.110 , pp. 161-167
    • Noe, S.N.1    Newton, C.2    Widen, R.3    Friedman, H.4    Klein, T.W.5
  • 79
    • 18544397160 scopus 로고    scopus 로고
    • Expression of the CB1 cannabinoid receptor in macrophage-like cells from brain tissue: Immunochemical characterization by fusion protein antibodies
    • Sinha, D., Bonner, T. I., Bhat, N. R., Matsuda, L. A. (1998) Expression of the CB1 cannabinoid receptor in macrophage-like cells from brain tissue: immunochemical characterization by fusion protein antibodies. J. Neuroimmunol. 82, 13-21.
    • (1998) J. Neuroimmunol. , vol.82 , pp. 13-21
    • Sinha, D.1    Bonner, T.I.2    Bhat, N.R.3    Matsuda, L.A.4
  • 80
    • 0036373102 scopus 로고    scopus 로고
    • Presence and regulation of the endocannabinoid system in human dendritic cells
    • Matias, I., Pochard, P., Orlando, P., Salzet, M., Pestel, J., Di Marzo, V. (2002) Presence and regulation of the endocannabinoid system in human dendritic cells. Eur. J. Biochem. 269, 3771-3778.
    • (2002) Eur. J. Biochem. , vol.269 , pp. 3771-3778
    • Matias, I.1    Pochard, P.2    Orlando, P.3    Salzet, M.4    Pestel, J.5    Di Marzo, V.6
  • 81
    • 0030087688 scopus 로고    scopus 로고
    • Cannabinoid receptor proteins are increased in Jurkat, human T-cell line after mitogen activation
    • Daaka, Y., Friedman, H., Klein, T. W. (1996) Cannabinoid receptor proteins are increased in Jurkat, human T-cell line after mitogen activation. J. Pharmacol. Exp. Ther. 276, 776-783.
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , pp. 776-783
    • Daaka, Y.1    Friedman, H.2    Klein, T.W.3
  • 82
    • 0033545866 scopus 로고    scopus 로고
    • Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
    • Zimmer, A., Zimmer, A. M., Hohmann, W. G., Herkenham, M., Bonner, T. I. (1999) Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc. Natl. Acad. Sci. USA 96, 5780-5785.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5780-5785
    • Zimmer, A.1    Zimmer, A.M.2    Hohmann, W.G.3    Herkenham, M.4    Bonner, T.I.5
  • 84
    • 0035816415 scopus 로고    scopus 로고
    • Differential expression of cannabinoid CB2 receptor mRNA in mouse immune cell subpopulations and following B cell stimulation
    • Lee, S. F., Newton, C., Widen, R., Friedman, H., Klein, T. W. (2001) Differential expression of cannabinoid CB2 receptor mRNA in mouse immune cell subpopulations and following B cell stimulation. Eur. J. Pharmacol. 423, 235-241.
    • (2001) Eur. J. Pharmacol. , vol.423 , pp. 235-241
    • Lee, S.F.1    Newton, C.2    Widen, R.3    Friedman, H.4    Klein, T.W.5
  • 85
    • 0035191240 scopus 로고    scopus 로고
    • Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation
    • Carlisle, S., Marciano-Cabral, F., Staab, A., Ludwick, C., Cabral, G. (2002) Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation. Int. Immunopharmacol. 2, 69-82.
    • (2002) Int. Immunopharmacol. , vol.2 , pp. 69-82
    • Carlisle, S.1    Marciano-Cabral, F.2    Staab, A.3    Ludwick, C.4    Cabral, G.5
  • 90
    • 0026611540 scopus 로고
    • 9-Tetrahydrocannabinol suppresses concanavalin A induced increase in cytoplasmic free calcium in mouse thymocytes
    • 9-Tetrahydrocannabinol suppresses concanavalin A induced increase in cytoplasmic free calcium in mouse thymocytes. Life Sci. 51, 151-160.
    • (1992) Life Sci. , vol.51 , pp. 151-160
    • Yebra, M.1    Klein, T.W.2    Friedman, H.3
  • 91
    • 0026636838 scopus 로고
    • Inhibition of adenylate cyclase by 9-tetrahydrocannabinol in mouse spleen cells: A potential mechanism for cannabinoid-mediated immunosuppression
    • Schatz, A. R., Kessler, F. K., Kaminski, N. E. (1992) Inhibition of adenylate cyclase by 9-tetrahydrocannabinol in mouse spleen cells: a potential mechanism for cannabinoid-mediated immunosuppression. Life Sci. 51, PL25-PL30.
    • (1992) Life Sci. , vol.51
    • Schatz, A.R.1    Kessler, F.K.2    Kaminski, N.E.3
  • 92
    • 0027998221 scopus 로고
    • Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G-protein coupled mechanism
    • Kaminski, N., Koh, W. S., Yang, K. H., Lee, M., Kessler, F. K. (1994) Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G-protein coupled mechanism. Biochem. Pharmacol. 48, 1899-1908.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1899-1908
    • Kaminski, N.1    Koh, W.S.2    Yang, K.H.3    Lee, M.4    Kessler, F.K.5
  • 93
    • 0019921627 scopus 로고
    • Effect of a clonal cell line with NK activity on bone marrow transplants, tumor development and metastasis in vivo
    • Warner, J. F., Dennert, G. (1982) Effect of a clonal cell line with NK activity on bone marrow transplants, tumor development and metastasis in vivo. Nature (Lond.) 300, 31-34.
    • (1982) Nature (Lond.) , vol.300 , pp. 31-34
    • Warner, J.F.1    Dennert, G.2
  • 94
    • 0007827240 scopus 로고    scopus 로고
    • Role of nuclear factor of activated T-cells and activator protein-1 in the inhibition of interleukin-2 gene transcription by cannabinol in EL4 T-cells
    • Yea, S. S., Yang, K. H., Kaminski, N. E. (2000) Role of nuclear factor of activated T-cells and activator protein-1 in the inhibition of interleukin-2 gene transcription by cannabinol in EL4 T-cells. J. Pharmacol. Exp. Ther. 292, 597-605.
    • (2000) J. Pharmacol. Exp. Ther. , vol.292 , pp. 597-605
    • Yea, S.S.1    Yang, K.H.2    Kaminski, N.E.3
  • 95
    • 17544371574 scopus 로고    scopus 로고
    • Cannabinoid induction of adenylate cyclase-mediated signal transduction and interleukin 2 (IL-2) expression in the murine T-cell line, EL4.IL-2
    • Condie, R., Herring, A., Koh, W. S., Lee, M., Kaminski, N. E. (1996) Cannabinoid induction of adenylate cyclase-mediated signal transduction and interleukin 2 (IL-2) expression in the murine T-cell line, EL4.IL-2. J. Biol. Chem. 271, 13175-13183.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13175-13183
    • Condie, R.1    Herring, A.2    Koh, W.S.3    Lee, M.4    Kaminski, N.E.5
  • 96
    • 0033800314 scopus 로고    scopus 로고
    • AP-1 activity is negatively regulated by cannabinol through inhibition of its protein components, c-fos and c-jun
    • Faubert, B. L., Kaminski, N. E. (2000) AP-1 activity is negatively regulated by cannabinol through inhibition of its protein components, c-fos and c-jun. J. Leukoc. Biol. 67, 259-266.
    • (2000) J. Leukoc. Biol. , vol.67 , pp. 259-266
    • Faubert, B.L.1    Kaminski, N.E.2
  • 97
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri, G. (2003) Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3, 133-146.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 98
    • 0037143111 scopus 로고    scopus 로고
    • Increased emotional distress in daughters of breast cancer patients is associated with decreased natural cytotoxic activity, elevated levels of stress hormones and decreased secretion of Th1 cytokines
    • Cohen, M., Klein, E., Kuten, A., Fried, G., Zinder, O., Pollack, S. (2002) Increased emotional distress in daughters of breast cancer patients is associated with decreased natural cytotoxic activity, elevated levels of stress hormones and decreased secretion of Th1 cytokines. Int. J. Cancer 100, 347-354.
    • (2002) Int. J. Cancer , vol.100 , pp. 347-354
    • Cohen, M.1    Klein, E.2    Kuten, A.3    Fried, G.4    Zinder, O.5    Pollack, S.6
  • 100
    • 0033666278 scopus 로고    scopus 로고
    • Norepinepbrine: A messenger from the brain to the immune system
    • Kohm, A. P., Sanders, V. M. (2000) Norepinepbrine: a messenger from the brain to the immune system. Immunol. Today, 21, 539-542.
    • (2000) Immunol. Today , vol.21 , pp. 539-542
    • Kohm, A.P.1    Sanders, V.M.2
  • 101
    • 0028065110 scopus 로고
    • Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection
    • Newton, C. A., Klein, T. W., Friedman, H. (1994) Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection. Infect. Immun. 62, 4015-4020.
    • (1994) Infect. Immun. , vol.62 , pp. 4015-4020
    • Newton, C.A.1    Klein, T.W.2    Friedman, H.3
  • 102
    • 0034660138 scopus 로고    scopus 로고
    • 9-Tetrahydrocannabinol treatment suppresses immunity and early IFN-γ, IL-12, and IL-12 receptor β2 responses to Legionella pneumophila infection
    • 9-Tetrahydrocannabinol treatment suppresses immunity and early IFN-γ, IL-12, and IL-12 receptor β2 responses to Legionella pneumophila infection. J. Immunol. 164, 6461-6466.
    • (2000) J. Immunol. , vol.164 , pp. 6461-6466
    • Klein, T.W.1    Newton, C.A.2    Nakachi, N.3    Friedman, H.4
  • 104
    • 0035800564 scopus 로고    scopus 로고
    • Modulation of cytokine responses in Corynebacterium parvum-primed endotoxemic mice by centrally administered cannabinoid ligands
    • Smith, S. R., Terminelli, C., Denhardt, G. (2001) Modulation of cytokine responses in Corynebacterium parvum-primed endotoxemic mice by centrally administered cannabinoid ligands. Eur. J. Pharmacol. 425, 73-83.
    • (2001) Eur. J. Pharmacol. , vol.425 , pp. 73-83
    • Smith, S.R.1    Terminelli, C.2    Denhardt, G.3
  • 105
    • 0034235808 scopus 로고    scopus 로고
    • Δ-9-Tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway
    • Zhu, L. X., Sharma, S., Stolina, M., Gardner, B., Roth, M. D., Tashkin, D. P., Dubinett, S. M. (2000) Δ-9-Tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway. J. Immunol. 165, 373-380.
    • (2000) J. Immunol. , vol.165 , pp. 373-380
    • Zhu, L.X.1    Sharma, S.2    Stolina, M.3    Gardner, B.4    Roth, M.D.5    Tashkin, D.P.6    Dubinett, S.M.7
  • 106
    • 0036889699 scopus 로고    scopus 로고
    • Δ9-Tetrahydrocannabinol regulates Th1/Th2 cytokine balance in activated human T cells
    • Yuan, M., Kiertscher, S. M., Cheng, Q., Zoumalan, R., Tashkin, D. P., Roth, M. D. (2002) Δ9-Tetrahydrocannabinol regulates Th1/Th2 cytokine balance in activated human T cells. J. Neuroimmunol. 133, 124-131.
    • (2002) J. Neuroimmunol. , vol.133 , pp. 124-131
    • Yuan, M.1    Kiertscher, S.M.2    Cheng, Q.3    Zoumalan, R.4    Tashkin, D.P.5    Roth, M.D.6
  • 107
    • 0036679172 scopus 로고    scopus 로고
    • Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain
    • Szabo, I., Chen, X. H., Xin, L., Adler, M. W., Howard, O. M., Oppenheim, J. J., Rogers, T. J. (2002) Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain. Proc. Natl. Acad. Sci. USA 99, 10276-10281.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 10276-10281
    • Szabo, I.1    Chen, X.H.2    Xin, L.3    Adler, M.W.4    Howard, O.M.5    Oppenheim, J.J.6    Rogers, T.J.7
  • 108
    • 0034717138 scopus 로고    scopus 로고
    • Genomic and functional changes induced by the activation of the peripheral cannabinoid receptor CB2 in the promyelocytic cells HL-60. Possible involvement of the CB2 receptor in cell differentiation
    • Derocq, J. M., Jbilo, O., Bouaboula, M., Segui, M., Clere, C., Casellas, P. (2000) Genomic and functional changes induced by the activation of the peripheral cannabinoid receptor CB2 in the promyelocytic cells HL-60. Possible involvement of the CB2 receptor in cell differentiation. J. Biol. Chem. 275, 15621-15628.
    • (2000) J. Biol. Chem. , vol.275 , pp. 15621-15628
    • Derocq, J.M.1    Jbilo, O.2    Bouaboula, M.3    Segui, M.4    Clere, C.5    Casellas, P.6
  • 109
    • 0037089221 scopus 로고    scopus 로고
    • Hematopoietic cells expressing the peripheral cannabinoid receptor migrate in response to the endocannabinoid 2-arachidonoylglycerol
    • Jorda, M. A., Verbakel, S. E., Valk, P. J., Vankan-Berkhoudt, Y. V., Maccarrone, M., Finazzi-Agro, A., Lowenberg, B., Delwel, R. (2002) Hematopoietic cells expressing the peripheral cannabinoid receptor migrate in response to the endocannabinoid 2-arachidonoylglycerol. Blood 99, 2786-2793.
    • (2002) Blood , vol.99 , pp. 2786-2793
    • Jorda, M.A.1    Verbakel, S.E.2    Valk, P.J.3    Vankan-Berkhoudt, Y.V.4    Maccarrone, M.5    Finazzi-Agro, A.6    Lowenberg, B.7    Delwel, R.8
  • 112
    • 0027999501 scopus 로고
    • Anandamide, an endogenous cannabinoid receptor agonist, inhibits lymphocyte proliferation and induces apoptosis
    • Schwarz, H., Blanco, F. J., Lotz, M. (1994) Anandamide, an endogenous cannabinoid receptor agonist, inhibits lymphocyte proliferation and induces apoptosis. J. Neuroimmunol. 55, 107-115.
    • (1994) J. Neuroimmunol. , vol.55 , pp. 107-115
    • Schwarz, H.1    Blanco, F.J.2    Lotz, M.3
  • 113
    • 0032219623 scopus 로고    scopus 로고
    • 9-Tetrahydrocannabinol induces apoptosis in macrophages and lymphocytes: Involvement of Bcl-2 and caspase-1
    • 9-Tetrahydrocannabinol induces apoptosis in macrophages and lymphocytes: involvement of Bcl-2 and caspase-1. J. Pharmacol. Exp. Ther. 286, 1103-1109.
    • (1998) J. Pharmacol. Exp. Ther. , vol.286 , pp. 1103-1109
    • Zhu, W.1    Friedman, H.2    Klein, T.W.3
  • 114
    • 17344380844 scopus 로고    scopus 로고
    • Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
    • Galve-Roperh, I., Sanchez, C., Cortes, M. L., del Pulgar, T. G., Izquierdo, M., Guzman, M. (2000) Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat. Med. 6, 313-319.
    • (2000) Nat. Med. , vol.6 , pp. 313-319
    • Galve-Roperh, I.1    Sanchez, C.2    Cortes, M.L.3    Del Pulgar, T.G.4    Izquierdo, M.5    Guzman, M.6
  • 116
    • 0035200613 scopus 로고    scopus 로고
    • Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors
    • Jacobsson, S. O., Wallin, T., Fowler, C. J. (2001) Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors. J. Pharmacol. Exp. Ther. 299, 951-959.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 951-959
    • Jacobsson, S.O.1    Wallin, T.2    Fowler, C.J.3
  • 119
    • 0033405883 scopus 로고    scopus 로고
    • Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells
    • Melck, D., Rueda, D., Galve-Roperh, I., De Petrocellis, L., Guzman, M., Di Marzo, V. (1999) Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. FEBS Lett. 463, 235-240.
    • (1999) FEBS Lett. , vol.463 , pp. 235-240
    • Melck, D.1    Rueda, D.2    Galve-Roperh, I.3    De Petrocellis, L.4    Guzman, M.5    Di Marzo, V.6
  • 120
    • 0034465259 scopus 로고    scopus 로고
    • Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation
    • Melck, D., De Petrocellis, L., Orlando, P., Bisogno, T., Laezza, C., Bifulco, M., Di Marzo, V. (2000) Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation. Endocrinology 141, 118-126.
    • (2000) Endocrinology , vol.141 , pp. 118-126
    • Melck, D.1    De Petrocellis, L.2    Orlando, P.3    Bisogno, T.4    Laezza, C.5    Bifulco, M.6    Di Marzo, V.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.