Signal transduction pathways and transcriptional regulation in Th17 cell differentiation

Cytokine and Growth Factor Reviews

Volumn 21, Issue 6, 2010, Pages 425-434

  Hirahara, Kiyoshi ^a   Ghoreschi, Kamran ^a   Laurence, Arian ^a   Yang, Xiang Ping ^a   Kanno, Yuka ^a   O'Shea, John J ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

Cytokines; Epigenetics; Signal transduction; T cell differentiation; Th17; Transcription factor

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; G PROTEIN COUPLED RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 27; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MYELOID DIFFERENTIATION FACTOR 88; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN E2; RETINOID X RECEPTOR ALPHA; RETINOID X RECEPTOR GAMMA; SMAD2 PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR RUNX; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; AUTOIMMUNITY; BINDING SITE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR IMMUNITY; CHROMATIN IMMUNOPRECIPITATION; CYTOKINE PRODUCTION; EPIGENETICS; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HYPER IGE SYNDROME; MOLECULAR INTERACTION; NONHUMAN; PHENOTYPE; PLASTICITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MODIFICATION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TH17 CELL; TRANSCRIPTION REGULATION;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL LINEAGE; CORE BINDING FACTOR ALPHA SUBUNITS; EPIGENOMICS; HUMANS; INTERLEUKIN-17; INTERLEUKIN-23; INTERLEUKIN-6; LYSOPHOSPHOLIPIDS; MICE; MICRORNAS; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; RETINOID X RECEPTORS; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SPHINGOSINE; STAT3 TRANSCRIPTION FACTOR; TH17 CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 78649689761     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cytogfr.2010.10.006     Document Type: Article

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