TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1

Nature Medicine

Volumn 13, Issue 6, 2007, Pages 711-718

  Amadi Obi, Ahjoku ^a   Yu, Cheng Rong ^a   Liu, Xuebin ^a   Mahdi, Rashid M ^a   Clarke, Grace Levy ^a   Nussenblatt, Robert B ^a   Gery, Igal ^a   Lee, Yun Sang ^a   Egwuagu, Charles E ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FREUND ADJUVANT; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ANTIBODY; INTERLEUKIN 27; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; GROWTH INHIBITOR; IL27 PROTEIN, HUMAN; IL27 PROTEIN, MOUSE; INTERLEUKIN DERIVATIVE; STAT1 PROTEIN, HUMAN; STAT1 PROTEIN, MOUSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; HELPER CELL; IMMUNOPATHOGENESIS; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; SCLERITIS; TARGET ORGAN; UPREGULATION; UVEITIS; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; COCULTURE; COMPARATIVE STUDY; CYTOLOGY; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PHYSIOLOGY; VALIDATION STUDY;

RODENTIA;

ANIMALS; AUTOIMMUNE DISEASES; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; GROWTH INHIBITORS; HUMANS; INTERLEUKIN-2; INTERLEUKINS; MICE; MICE, INBRED C57BL; ORGAN CULTURE TECHNIQUES; SCLERITIS; STAT1 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, HELPER-INDUCER; UVEITIS;

EID: 34250005444     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1585     Document Type: Article

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