Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice

Journal of Clinical Investigation

Volumn 120, Issue 9, 2010, Pages 3280-3295

  Biswas, Partha S ^a   Gupta, Sanjay ^a   Chang, Emily ^a   Song, Li ^a   Stirzaker, Roslynn A ^a   Liao, James K ^b   Bhagat, Govind ^a   Pernis, Alessandra B ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 17; INTERLEUKIN 21; PROTEIN SERINE THREONINE KINASE; RHO ASSOCIATED COILED CONTAINING PROTEIN KINASE 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; INFLAMMATION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE; TH17 CELL;

ANIMALS; AUTOIMMUNITY; CELL DIFFERENTIATION; INTERFERON REGULATORY FACTORS; INTERLEUKIN-17; INTERLEUKINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RHO-ASSOCIATED KINASES; T-LYMPHOCYTES;

EID: 77956361520     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI42856     Document Type: Article

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